• Title/Summary/Keyword: G.711

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Antimicrobial Characteristics of Paeonia lactiflora Pall. Extract Tested against Food-putrefactive Microorganisms (작약추출물의 식품변패미생물에 대한 항균특성)

  • Park, Ki-Duck;Cho, Sung-Hwan
    • Food Science and Preservation
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    • v.17 no.5
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    • pp.706-711
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    • 2010
  • Paeonia lactiflora Pall. was extracted with water and the Paeonia lactiflora Pall. extract (PLE) was tested for antimicrobial activities against Corynebacterium xerosis, Candida albicans, Listeria monocytogenes and Pseudomonas syringae. PLE showed pronounced antimicrobial effects at concentrations at or above 50 ${\mu}g$/mL. The activities were stable at $100^{\circ}C$ and over the pH range of 3-11. PLE may serve as a natural antimicrobial agent in food preservation. It is suggested that hydrophillic components in the extract synergistically perturb microbial membrane functions.

The influence of MgO on the radiation protection and mechanical properties of tellurite glasses

  • Hanfi, M.Y.;Sayyed, M.I.;Lacomme, E.;Akkurt, I.;Mahmoud, K.A.
    • Nuclear Engineering and Technology
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    • v.53 no.6
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    • pp.2000-2010
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    • 2021
  • Mechanical moduli, such as Young's modulus (E), Bulks modulus (B), Shear modulus (S), longitudinal modulus (L), Poisson's ratio (σ) and micro Hardness (H) were theoretically calculated for (100-x)TeO2+x MgO glasses, where x = 10, 20, 30, 40 and 45 mol%, based on the Makishima-Mackenzie model. The estimated results showed that the mechanical moduli and the microhardness of the glasses were improved with the increase of the MgO contents in the TM glasses, while Poisson's ratio decreased with the increase in MgO content. Moreover, the radiation shielding capacity was evaluated for the studied TM glasses. Thus, the linear attenuation coefficient (LAC), mass attenuation coefficient (MAC), transmission factor (TF) and half-value thickness (𝚫0.5) were simulated for gamma photon energies between 0.344 and 1.406 MeV. The simulated results showed that glass TM10 with 10 mol % MgO possess the highest LAC and varied in the range between 0.259 and 0.711 cm-1, while TM45 glass with 45 mol % MgO possess the lowest LAC and vary in the range between 0.223 and 0.587 cm-1 at gamma photon energies between 0.344 and 1.406 MeV. Furthermore, the BXCOM program was applied to calculate the effective atomic number (Zeff), equivalent atomic number (Zeq) and buildup factors (EBF and EABF) of the glasses. The effective removal cross-section for the fast neutrons (ERCSFN, ∑R) was also calculated theoretically. The received data depicts that the lowest ∑R was achieved for TM10 glasses, where ∑R = 0.0193 cm2 g-1, while TM45 possesses the highest ERCSFN where ∑R = 0.0215 cm2 g-1.

Establishment of an Allo-Transplantable Hamster Cholangiocarcinoma Cell Line and Its Application for In Vivo Screening of Anti-cancer Drugs

  • Puthdee, Nattapong;Vaeteewoottacharn, Kulthida;Seubwai, Wunchana;Wonkchalee, Orasa;Keawkong, Worasak;Juasook, Amornrat;Pinloar, Somchai;Pairojkul, Chawalit;Wongkham, Chaisiri;Okada, Seiji;Boonmars, Thidarut;Wongkham, Sopit
    • Parasites, Hosts and Diseases
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    • v.51 no.6
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    • pp.711-717
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    • 2013
  • Opisthorchis viverrini (O. viverrini) is a well-known causative agent of cholangiocarcinoma (CCA) in humans. CCA is very resistant to chemotherapy and is frequently fatal. To understand the pathogenesis of CCA in humans, a rodent model was developed. However, the development of CCA in rodents is time-consuming and the xenograft-transplantation model of human CCA in immunodeficient mice is costly. Therefore, the establishment of an in vivo screening model for O. viverrini-associated CCA treatment was of interest. We developed a hamster CCA cell line, Ham-1, derived from the CCA tissue of O. viverrini-infected and N-nitrosodimethylamine-treated Syrian golden hamsters. Ham-1 has been maintained in Dulbecco's Modified Essential Medium supplemented with 10% fetal bovine serum for more than 30 subcultures. These cells are mostly diploid (2n=44) with some being polyploid. Tumorigenic properties of Ham-1 were demonstrated by allograft transplantation in hamsters. The transplanted tissues were highly proliferative and exhibited a glandular-like structure retaining a bile duct marker, cytokeratin 19. The usefulness of this for in vivo model was demonstrated by berberine treatment, a traditional medicine that is active against various cancers. Growth inhibitory effects of berberine, mainly by an induction of G1 cell cycle arrest, were observed in vitro and in vivo. In summary, we developed the allo-transplantable hamster CCA cell line, which can be used for chemotherapeutic drug testing in vitro and in vivo.

Electromagnetic Wave and EMF Attenuation by Shielding Materials in home appliances (가전제품 전자파 현황 및 차폐재에 의한 감쇄 효과)

  • Cho, Jae-Cheol;Park, Jae-Hwan
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.9 no.6
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    • pp.711-718
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    • 2019
  • Spectrum analyzer and electromagnetic field meter were used to investigate the EM generation behaviour in different types of home electrical appliances. During microwave oven operation, the EM power measured at a point 30cm apart was measured in the range of 8~11mW/㎡, the strength of the low frequency magnetic field was 60~80mG and the electric field strength was measured at 150~160V/m. For smart phone wireless charging pad, it was measured at an electromagnetic power of 0.4mW/㎡, an electric field of 160 V/m and a magnetic field of 1mG at a point 10cm away. For microwave oven and wireless charging pad, if used within 10cm, the size of the electric field has been measured at a large value that exceeds the human body protection standard and may be hazardous to humans. On the other hand, home appliances such as TVs, hairdryers and refrigerators all showed very low levels of electromagnetic waves, electric fields and magnetic fields, with no harmful effects seen. For electromagnetic shielding, the metal Cu fabric and metal foil had a high level of EM shielding, while polymer films had a low EM shielding characteristic.

Effects of dietary humic acid and enzymes on meat quality and fatty acid profiles of broiler chickens fed canola-based diets

  • Disetlhe, Amogelang R.P.;Marume, Upenyu;Mlambo, Victor;Hugo, Arno
    • Asian-Australasian Journal of Animal Sciences
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    • v.32 no.5
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    • pp.711-720
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    • 2019
  • Objective: This study was conducted to assess the effect of potassium humate and enzymes (Xylanase+Amylase+Protease) inclusion in diets on carcass characteristics, meat quality and fatty acid profiles of broilers fed canola-based diets. Methods: Two hundred and twenty broilers randomly allotted to 5 dietary treatments: the control (commercial broiler diet); CM (17.5% canola meal inclusion); CMEnz (17.5% CM inclusion+0.3 g/kg Axtra XAP); CMPh (17.5% CM inclusion+1.5% Potassium Humate, PH); and CMEnzPh (17.5% CM inclusion+1.5% PH+0.3 g/kg Axtra XAP) were slaughtered at day 42 for assessment of carcass and meat quality parameters. Results: Diet had no effect on carcass traits apart from breast muscle weight and breast muscle index. The highest breast muscle weight was observed in broilers fed CMEnz ($487.6{\pm}17.5g$) followed by those fed the control diet ($474.37{\pm}17.5g$). Diet also had no significant dietary effect on pH, temperature, drip loss and shear force values of the breast muscle. However, diet significantly affected meat colour and water-holding capacity. Broilers in the control and CMPh groups ($52.94{\pm}0.67$ and $52.91{\pm}0.67$) had the highest (p<0.05) values for lightness ($L^*$), whilst those fed CMEnzPh had the lowest value ($47.94{\pm}0.67$). In contrast, CM group had the lowest (p<0.05) value for redness ($a^*$) with CMEnzPh group having the highest values. The proportion of polyunsaturated fatty acids (PUFAs), n-6 and n-3 fatty acids and the PUFA/saturated fatty acid ratio were increased in CM-based diets containing enzymes and humic acid. Conclusion: It can, therefore, be concluded that CM can be included in broiler diets in the presence of enzymes and humic acid with positive effects on meat quality and important fatty acids that are beneficial to the health of consumers.

Induction of Quinone Reductase Activity in Hepatoma Cells by Paprika (Capsicum annuum L.) (파프리카 추출물이 quinone reductase 유도활성에 미치는 영향)

  • Yu, Mi-Hee;Lee, Hyo-Jung;Im, Hyo-Gwon;Lee, Syng-Ook;Lee, In-Seon
    • Korean Journal of Food Science and Technology
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    • v.38 no.5
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    • pp.707-711
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    • 2006
  • Phase 2 enzymes are transcriptionally induced by a wide variety of chemical agents and natural products, and their induction plays a critical role in protection against chemical carcinogens and other toxic xenobiotics. The activity of the methanol extract and fractions of paprika (Capsicum annuum L.) was examined in murine Hepa1c1c7 cells for the induction of nicotinamide adenine dinucleotide (phosphate) NAD(P)H/quinone reductase (QR). The ethyl acetate (EtOAc) fraction induced QR activity in a dose-dependent manner in the concentration range of 10 to $500\;{\mu}g/mL$ with a maximum of a 3.3-fold increase in induction. The EtOAc fraction also showed high QR induction potency in Ah-receptor-defective mutant of Hepa 1c1c7 cells ($BP^rcl$ cells), which indicates that this fraction is a monofunctional inducer of QR. These results suggest that useful cancer chemopreventive materials could be isolated from EtOAc fraction of Paprika.

Comparison of Physicochemical Properties between Extracts and Soaked Liquor of Lespedeza cuneata G.Don (비수리(Lespedeza cuneata G.Don) 추출물과 담금주의 이화학적 특성비교)

  • Jeong, Kap-Seop
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.12
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    • pp.705-711
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    • 2017
  • Lespedeza cuneata (LC) is a herbaceous plant that grows throughout Korea. To investigate the physicochemical properties and the antioxidant activities of LC extracts and LC-soaked liquor (s. liquor), extraction with distilled water (DW) and ethanol was conducted and the extracts were compared with s. liquor. A total of 22 free amino acids from LC extract were detected, with the main ones being phosphoethanolamine 20.36>L-proline 18.02>ammonia 14.48>L-aspartic acid 12.96>${\gamma}$-amino-n-butyric acid 10.67%. The total flavonoid contents (TFC) and total phenolics contents (TPC) were in the order of s. liquor>DW>ethanol extract. The electron donating ability based on DPPH radical scavenging ability was highest for s.liquor, which equivalents 81.4% ascorbic acid in the order of s. liquor>ethanol>DW extract. The orders of ferric reducing antioxidant power and ABTS radical scavenging ability were proportional to the TFC and TPC of extracts, and in the order of s. liquor>ethanol>DW extract. The nitrite scavenging ability of s. liquor was highest among the three extracts (96.6% at pH 1.2), which was 2.6 times greater than that of DW extract.

Nutritional Environment Influences Hypertension in the Middle-aged Korean Adults - based on 1998 & 2001 National Health and Nutrition Survey - (한국 중년성인의 고혈압과 영양환경요인의 관련성 - 1998년과 2001년 국민건강.영양조사 결과에 근거하여 -)

  • Lee, Hae-Jeung;Lee, Haeng-Shin;Lee, Yoon-Na;Jang, Young-Ai;Moon, Jae-Jin;Kim, Cho-Il
    • Korean Journal of Community Nutrition
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    • v.12 no.3
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    • pp.272-283
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    • 2007
  • This study was performed to delineate the relationship between lifestyle and nutritional risk factors associated with hypertension in representative middle-aged Korean population. Hypertension in this study is defined as hypertensive ($SBP{\geq}140mmHg\;or\;DBP{\geq}90mmHg$) adults without recognition of a disease state before a health exam. With data from the 1998 and 2001 National Health and Nutritional Survey, nutrient intakes of 6,112 adults, 40-64 years of age were calculated using food composition database and matched with health examination records by individual ID. After excluding those with extreme intake values, the number of final subjects included in the analysis was 5,200 (male 2,458, female 2,742). Using logistic regression method, socio-demographic data, lifestyle factors, and nutrient intakes were analyzed. Risky factors for hypertension revealed in this study were age, sex, BMI over 23, waist circumference, alcohol intake of more than 16g (male) or 8g (female). Regarding nutrient intakes, the intakes of highest quartile for energy (${\geq}2363.0kcal$) and protein (${\geq}90.2g$) were significantly associated with higher risk of hypertension after adjusting for age, sex, and other socio-demographic factors (OR=1.312(1.046-1.711), OR=1.488(1.194-1.854), respectively)). Although high intakes of sodium (${\geq}6604.0mg$) and phosphorus seemed to be risk factors of hypertension also before energy adjustment (OR=1.278(1.034-1.581), OR=1.280(1.024-1.600), respectively), only high intakes of energy and protein remained significant after adjustment. This study revealed that modifying risky lifestyles and dietary patterns, especially high energy intake, high protein intake, and high alcohol drinking, in middle-aged Korean adults could result in a prevalence decrease and/or prevention of hypertension.

The Meteorological, Physical, and Chemical Characteristics of Aerosol during Haze Event in May 2003 (2003년 5월의 연무 관측시 에어로졸의 기상 · 물리 · 화학 특성)

  • Lim, Ju-Yeon;Chun, Young-Sin;Cho, Kyoung-Mi;Lee, Sang-Sam;Shin, Hye-Jung
    • Journal of Korean Society for Atmospheric Environment
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    • v.20 no.5
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    • pp.697-711
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    • 2004
  • Severe haze, mist, and fog phenomena occurred in the central part of Korea during 15~25 May 2003 resulted in poor visibility and air quality. When these phenomena occurred, Korean peninsula was under the effects of anticyclone. The atmosphere was stable, and wind speed was so weak. Under this meteorological conditions, air quality was worse and worse. The characteristics of aerosol in Seoul, Incheon, and Gosan (Jeju) during this period are investigated from the $PM_{10}$. TSP concentrations and aerosol number concentrations. Concentrations of $PM_{10}$ and TSP measured at KMA increased upto 176 and 230 J.${\mu}g/m^3$ on 22 May 2003, respectively. Aerosol number concentrations of size range from 0.82 to 6.06 ${\mu}m$ increased in Seoul on 17, 19, and 21~24 May 2003, and the concentrations of $NO_2$ and $SO_2$had maximum value of 0.165 ppm at Gwanak Mt. and 0.036 ppm at Guro-dong on 23 May 2003, respectively. Result from analysis on heavy metal elements showed high concentrations of Zn, Pb, Cr, Ni, Cu, and Cd during 20~24 May 2003. This event is examined by comprehensive analyses of synoptic weather conditions, satellite images, concentrations of suspended particles and air pollutants, and heavy metal elements.

The Effect of BuOH Fraction of Polygonatum odoratum with Selenium on Blood Glucose Level and Lipid Peroxidation in Streptozotocin Induced Diabetic Rats (둥굴레 분획물과 Selenium이 Streptozotocin 유발 당뇨 흰쥐의 혈당수준과 지질과산화에 미치는 영향)

  • 임숙자
    • Journal of Nutrition and Health
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    • v.33 no.7
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    • pp.703-711
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    • 2000
  • The purpose of this study was to investigate the effect of butanol(BuOH) fraction of Polygonatum odoratum with selenium tr-eatment on blood glucose levels and lipid peroxidations in streptozotocin(STZ) induced diabetric rats. Male Sprague-Dawly rats weighing(180-200g) were divided into five groups : normal STZ-control and three expreimental groups(P, odoratum group P, odo-Se group and Se group) Diabetes mellitus was induced by injection STZ in the tail vein at the dose of 45mg/kg B.W The BuOH fraction of Polygonatum odoratum(500mg/kg. B,W) given orally administered for 14 days. The Se treated group were fed a AIN-76 recommendation diet mixed with Na2Seo3(2mg/kg diet). Diabetic rats showed the lower weight gain compared to the normal rats. the plasma glucose levels of the P. odo-Se group were significantly lower than the other experimental groups. The plasma cholesterol levels were higher in STZ-control and Se groups compared toP.odoratum and P. odo-Se groups and HDL-cholesterol levels were increased in the diabetic experimental groups fed on BuOH fraction of P. odoratum with Se supplementation. The liver and muscle glycogen levels were not significantly differ among all groups. The plasma free fatty acid levels were lower in diabetic experimental groups fed on BuOh fraction of P. odoratum or Se sup-plementation than STZ-control and Se groups. Diabetics rats showed the higher levels of triglyceride in plasma andlower levels in liver compared with the normal group. Supplementation with Se decreased significantly the liver triglyceride level. The MDA levels in liver and kidney were significantly reduced in all the experimental groups. In conclusion administration of BuOH fraction of Polygonatuum odoratum with selenium supplementation reduced blood glucose levels and peroxdative tissue damage in STZ induced diabetic rats showing the possibility of preventiave and therapeutic use of the wild edible plant to the diabetes mellitus.

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