• Korean Journal of Acupuncture
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• 제27권3호
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• pp.129-142
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• 2010

Background : The Bonghan theory is a hypothesis on the anatomical structure of the acupuncture point and meridian system. It has been regarded as a misunderstanding of the lymphatic system, or as a made-up story, for the past 40 years. Since 2002, Many studies have been published either to support the theory or to refute the old viewpoint. Objective : The purpose of this study was to find out the validity of the refutation by reviewing the publications. Methods : Searches were made from online databases (Riss4u.net, Google.com, Sciencedirect.com, Pubmed.com, baidu.com, and ci.nii.ac.jp) from 1960 to 2009. The search terms that were used were "Bonghan," "Bong han," "봉한," "thread-like structure," "KИM БOH XaHOM", "CИCTEMA KEHPAK," "鳳漢," "鳳漢管," and "鳳漢学說." References from the searched publications were also used. Results : Since the 1960s, 107 publications were identified as related works, but only 11 publications sought to refute the Bonghan theory. Two publications were researches, and nine were reviews. In the analysis of the correlation of the arguments with the publication contents, it was found that the research of G. Kellner reviewed the Bonghan system properly but that V. V. Kosmatov did not classify the ear-reflex zone as a traditional acupuncture point. For the review publications, only two reviews contained proper arguments, but seven publications were identified as broad interpretations, wrong translations, etc. Moreover, the two proper reviews were grounded on the research of G. Kellner. Conclusions : We found that the scientific origin of the refutation of the Bonghan theory is only one research by G. Kellner. This result suggest that Bonghan theory was not discussed enough to determine the invention.

• Journal of Microbiology and Biotechnology
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• 제31권10호
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• pp.1438-1445
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• 2021

A bifunctional glycoside hydrolase GH78 from the ascomycete Xylaria polymorpha (XpoGH78) possesses catalytic versatility towards both glycosides and esters, which may be advantageous for the efficient degradation of the plant cell-wall complex that contains both diverse sugar residues and esterified structures. The contribution of XpoGH78 to the conversion of lignocellulosic materials without any chemical pretreatment to release the water-soluble aromatic fragments, carbohydrates, and methanol was studied. The disintegrating effect of enzymatic lignocellulose treatment can be significantly improved by using different kinds of hydrolases and phenoloxidases. The considerable changes in low (3 kDa), medium (30 kDa), and high (> 200 kDa) aromatic fragments were observed after the treatment with XpoGH78 alone or with this potent cocktail. Synergistic conversion of rape straw also resulted in a release of 17.3 mg of total carbohydrates (e.g., arabinose, galactose, glucose, mannose, xylose) per gram of substrate after incubating for 72 h. Moreover, the treatment of rape straw with XpoGH78 led to a marginal methanol release of approximately 17 ㎍/g and improved to 270 ㎍/g by cooperation with the above accessory enzymes. In the case of beech wood conversion, the combined catalysis by XpoGH78 and laccase caused an effect comparable with that of fungal strain X. polymorpha in woody cultures concerning the liberation of aromatic lignocellulose fragments.