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Correlation between Peripheral Neuropathy and Cognitive Factors in Type 2 Diabetic Patients (제2형 당뇨병환자에서 말초신경병증과 인지기능항목의 상관관계)

  • Yang, Wonyul;Kim, Jong Kuk;Park, Kyung Won;Suh, Sunghwan;Lee, Hye-Jeong;Park, Mi-Kyoung
    • Journal of Life Science
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    • v.30 no.3
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    • pp.250-259
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    • 2020
  • Diabetes is a well-known risk factor for dementia and cognitive impairment. Diabetic polyneuropathy (DPN) is the most prevalent microvascular complication in type 2 diabetes mellitus (T2DM) patients. The purpose of this study was to evaluate the relation between diabetic peripheral polyneuropathy and cognitive factors in T2DM patients. Retrospective chart review of type 2 diabetic patients with results of a nerve conduction study (NCS) and a neurocognitive study. A total of 19 patients were included. DPN was defined using data from a nerve conduction study: a score of less than 24 in the Korean version of the Mini-Mental State Examination (K-MMSE) was considered as an indicator of cognitive impairment (CI). The mean age of the 19 patients was 71.6±5.0 years. The mean duration of diabetes was 8.4±9.1 years, and the mean HbA1c level was 8.1±1.8%. DPN was present in 7 of the 19 patients. Based on the K-MMSE score, CI was diagnosed in eight patients. The mean K-MMSE scores and the prevalence of CI was not different between the groups with and without DPN. There was no significant difference in DPN prevalence between the groups with and without CI. Education was significantly correlated with cognitive factors. Only the digit span-forward among the cognitive factors showed a significant negative correlation with nerve conduction velocity. In conclusion, the longer education period was associated with higher cognitive function and no significant correlation was observed between diabetic peripheral neuropathy and cognitive dysfunction in type 2 diabetic patients. Further prospective research is needed in the future.

A Study on the Conservation and Management of the Village Forest in Gyeonggi-do (경기도 마을숲의 보전 및 관리에 관한 연구)

  • Hwang, Dong-Kyu;Kim, Dong-Yeob
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.33 no.4
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    • pp.99-111
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    • 2015
  • The objectives of this study were to investigate the location, shape, environment, and vegetation of the Village Forest in Gyeonggi-do and to evaluate the ecological integration and changes of the Village Forests to figure out the measures for conservation and management. There were 23 Village Forests remain in Gyeonggi-do. Ten Village Forests were established based on Feng-shui background. Many of them were found in Yongin area and southeast of Icheon. The Village Forests were owned by local community at 9 village and privately owned at 8 villages. Most Village Forests were managed by local communities except for the two managed by private person. Fifty-two percent of the Village Forests were in strip shape, and most of them were established by Feng-shui background or for the prevention of disasters. The average size of the Village Forests was relatively small at 3,046m2. The most frequent tree species found at the Village Forest were Zelkova serrata and Pinus densiflora. Over half of the number of Village Forests showed vertical structure of overstory trees only or overstory-sub overstory combination, which seemed to be resulted from the loss of understory plants by the activities of local residents. The Village Forests that had over 30% of damaged trees were found at 7 villages. The damages were caused by the road construction close to the groves, soil compaction, and tree death by covering lower stem with soil. The vitality of the damaged trees seemed to be significantly low compared to that of the undamaged. There were factors that determined the changes in the Village Forests: community ritual, institutional protection, designation as a water resource protection district, road construction, land use change, windstorm hazards, and development of forest areas. In order to conserve and manage the Village Forests appropriately, it is necessary to limit excessive use of the grove areas and maintain proper tree growing conditions by improving the soil environment. The development of neighborhood areas need to be controlled and community activities should be encouraged to maintain or restore the original landscape of the groves. Protection measures and supporting policies need to be enforced to keep the Village Forests from disappearing in near future.

Mapping Precise Two-dimensional Surface Deformation on Kilauea Volcano, Hawaii using ALOS2 PALSAR2 Spotlight SAR Interferometry (ALOS-2 PALSAR-2 Spotlight 영상의 위성레이더 간섭기법을 활용한 킬라우에아 화산의 정밀 2차원 지표변위 매핑)

  • Hong, Seong-Jae;Baek, Won-Kyung;Jung, Hyung-Sup
    • Korean Journal of Remote Sensing
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    • v.35 no.6_3
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    • pp.1235-1249
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    • 2019
  • Kilauea Volcano is one of the most active volcano in the world. In this study, we used the ALOS-2 PALSAR-2 satellite imagery to measure the surface deformation occurring near the summit of the Kilauea volcano from 2015 to 2017. In order to measure two-dimensional surface deformation, interferometric synthetic aperture radar (InSAR) and multiple aperture SAR interferometry (MAI) methods were performed using two interferometric pairs. To improve the precision of 2D measurement, we compared root-mean-squared deviation (RMSD) of the difference of measurement value as we change the effective antenna length and normalized squint value, which are factors that can affect the measurement performance of the MAI method. Through the compare, the values of the factors, which can measure deformation most precisely, were selected. After select optimal values of the factors, the RMSD values of the difference of the MAI measurement were decreased from 4.07 cm to 2.05 cm. In each interferograms, the maximum deformation in line-of-sight direction is -28.6 cm and -27.3 cm, respectively, and the maximum deformation in the along-track direction is 20.2 cm and 20.8 cm, in the opposite direction is -24.9 cm and -24.3 cm, respectively. After stacking the two interferograms, two-dimensional surface deformation mapping was performed, and a maximum surface deformation of approximately 30.4 cm was measured in the northwest direction. In addition, large deformation of more than 20 cm were measured in all directions. The measurement results show that the risk of eruption activity is increasing in Kilauea Volcano. The measurements of the surface deformation of Kilauea volcano from 2015 to 2017 are expected to be helpful for the study of the eruption activity of Kilauea volcano in the future.

A Study on Integrated Logistic Support (통합병참지원에 관한 연구)

  • 나명환;김종걸;이낙영;권영일;홍연웅;전영록
    • Proceedings of the Korean Reliability Society Conference
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    • 2001.06a
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    • pp.277-278
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    • 2001
  • The successful operation of a product In service depends upon the effective provision of logistic support in order to achieve and maintain the required levels of performance and customer satisfaction. Logistic support encompasses the activities and facilities required to maintain a product (hardware and software) in service. Logistic support covers maintenance, manpower and personnel, training, spares, technical documentation and packaging handling, storage and transportation and support facilities.The cost of logistic support is often a major contributor to the Life Cycle Cost (LCC) of a product and increasingly customers are making purchase decisions based on lifecycle cost rather than initial purchase price alone. Logistic support considerations can therefore have a major impact on product sales by ensuring that the product can be easily maintained at a reasonable cost and that all the necessary facilities have been provided to fully support the product in the field so that it meets the required availability. Quantification of support costs allows the manufacturer to estimate the support cost elements and evaluate possible warranty costs. This reduces risk and allows support costs to be set at competitive rates.Integrated Logistic Support (ILS) is a management method by which all the logistic support services required by a customer can be brought together in a structured way and In harmony with a product. In essence the application of ILS:- causes logistic support considerations to be integrated into product design;- develops logistic support arrangements that are consistently related to the design and to each other;- provides the necessary logistic support at the beginning and during customer use at optimum cost.The method by which ILS achieves much of the above is through the application of Logistic Support Analysis (LSA). This is a series of support analysis tasks that are performed throughout the design process in order to ensure that the product can be supported efficiently In accordance with the requirements of the customer.The successful application of ILS will result in a number of customer and supplier benefits. These should include some or all of the following:- greater product uptime;- fewer product modifications due to supportability deficiencies and hence less supplier rework;- better adherence to production schedules in process plants through reduced maintenance, better support;- lower supplier product costs;- Bower customer support costs;- better visibility of support costs;- reduced product LCC;- a better and more saleable product;- Improved safety;- increased overall customer satisfaction;- increased product purchases;- potential for purchase or upgrade of the product sooner through customer savings on support of current product.ILS should be an integral part of the total management process with an on-going improvement activity using monitoring of achieved performance to tailor existing support and influence future design activities. For many years, ILS was predominantly applied to military procurement, primarily using standards generated by the US Government Department of Defense (DoD). The military standards refer to specialized government infrastructures and are too complex for commercial application. The methods and benefits of ILS, however, have potential for much wider application in commercial and civilian use. The concept of ILS is simple and depends on a structured procedure that assures that logistic aspects are fully considered throughout the design and development phases of a product, in close cooperation with the designers. The ability to effectively support the product is given equal weight to performance and is fully considered in relation to its cost.The application of ILS provides improvements in availability, maintenance support and longterm 3ogistic cost savings. Logistic costs are significant through the life of a system and can often amount to many times the initial purchase cost of the system.This study provides guidance on the minimum activities necessary to Implement effective ILS for a wide range of commercial suppliers. The guide supplements IEC60106-4, Guide on maintainability of equipment Part 4: Section Eight maintenance and maintenance support planning, which emphasizes the maintenance aspects of the support requirements and refers to other existing standards where appropriate. The use of Reliability and Maintainability studies is also mentioned in this study, as R&M is an important interface area to ILS.

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The Significance of Registration Convention and its Future Challenges in Space Law (등록협약의 우주법상 의의와 미래과제에 관한 연구)

  • Kim, Han-Taek
    • The Korean Journal of Air & Space Law and Policy
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    • v.35 no.2
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    • pp.375-402
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    • 2020
  • The adoption and entering into force of the Registration Convention was another achievement in expanding and strengthening the corpus iuris spatialis. It was the fourth treaty negotiated by the member states of the UNCOPUOS and it elaborates further Articles 5 and 8 of the Outer Space Treaty(OST). The Registration Convention also complements and strengthens the Article 11 of the OST, which stipulates an obligation of state parties to inform the UN Secretary-General of the nature, conduct, locations, and results of their space activities in order to promote international cooperation. The prevailing purposes of the Registration Convention is the clarification of "jurisdiction and control" as a comprehensive concept mentioned in Article 5 8 of the OST. In addition to its overriding objective, the Registration Convention also contributes to the promotion and the exploration and use of outer space for peaceful purposes. Establishing and maintaining a public register reduces the possibility of the existence of unidentified space objects and thereby lowers the risk such as, for example, putting the weapons of mass destruction secretly into orbit. And furthermore it could serve for a better space traffic management. The Registration Convention is a treaty established to implement Article 5 of OST for the rescue and return of astronaut in more detail. In this respect, if OST is a general law, the Registration Convention would be said to be in a special law. If two laws conflict the principle of lex specialis will be applied. Countries that have not joined the Registration Convention will have to follow the rules concerning the registration of paragraph 7 of the Declaration by the United Nations General Assembly resolution 1721 (X V I) in 1961. UN Resolution 1721 (XVI) is essentially non-binding, but appears to have evolved into the norm of customary international law requiring all States launching space objects into orbit or beyond to promptly provide information about their launchings for registration to the United Nations. However, the nature and scope of the information to be supplied is left to the discretion of the notifying State. The Registration Convention is a treaty created for compulsory registration of space objects by nations, but in reality it is a treaty that does not deviate from existing practice because it is based on voluntary registration. With the situation of dealing with new problems due to the commercialization and privatization of the space market, issues related to the definition of a 'space object', including matter of the registry state of new state that purchased space objects and space debris matter caused by the suspension of space objects launched by the registry state should be considered as matters when amendments, additional protocols or new Registration Convention are established. Also the question of registration of a flight vehicle in the commercial space market using a space vehicle traveling in a sub-orbital in a short time should be considered.

Suggestion on the Optimal Length of Long Tunnels Considering Traffic Safety Characteristics (교통안전 특성을 고려한 장대터널 적정길이 제시)

  • Kim, Joong-Hyo;Lee, Jeong-Hwan;Kwon, Sung Dae;Ha, Dong Ik
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.34 no.1
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    • pp.203-211
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    • 2014
  • Tunnel reduces travel time as and it is essential facilities for the eco-friendly road construction. In recent years, It has been accelerating the tunnel construction to provide a higher level of traffic service but a driver driving in the narrow and dark tunnel takes characteristically psychological anxiety and the restriction of the sight. Moreover, A driver passing through more than 1,000m long tunnel, as to pass inside the monotonous form of the tunnel for a long time can cause drowsiness and increase the driver load. This driver load can degrade road-holding of the inside of the long tunnel highly and pose a high risk of accidents. Accordingly, In this study is to present the proper length of the Tunnel, considering the characteristics of traffic accident. For this, this study is that the long tunnel that affects traffic safety traffic safety variables are selected and classified. Traffic safety variables are classified in detail as a variable of the traffic accident and velocity one, the applicable variables the number of the traffic accident, the ratio of the traffic accident, driving velocity, the individual vehicle velocity etc. Traffic safety variables are categorized as more than a pole length of the tunnel in order to examine its impact on correlation analysis. The results indicate significant results in traffic accidents in accordance with traffic accidents, traffic safety, selects the variable was Variable depending on the length of the tunnel traffic safety point of significantly increasing the possibility of an accident can be seen as a high point. And the point of the Distribution of selected variables in order to create a traffic safety was a significant increase in traffic safety variables was set at critical intervals. Before reaching the critical point and the corresponding length of the long tunnel was set at the proper length. In this study, the optimum length of the proposed long tunnel through the long tunnel that occur in the future to contribute to reducing traffic accidents would be able to be determined.

Concerning the Constitution Court's constitutional decision and the direction of supplemental legislation concerning Article 33 paragraph 8 of the Medical Service Act - With a focus on legitimacy of a system that prohibits multiple opening of medical instituion, in the content of 2014Hun-Ba212, August 29, 2019, 2014Hun-Ga15, 2015Hun-Ma561, 2016Hun-Ba21(amalgamation), Constitutional Court of Korea - ('의료법 제33조 제8항 관련 헌법재판소의 합헌결정'에 대한 평가 및 보완 입법 방향에 대하여 -헌법재판소 2019. 8. 29. 2014헌바212, 2014헌가15, 2015헌마561, 2016헌바21(병합) 결정의 내용 중 의료기관 복수 개설금지 제도의 당위성 및 필요성을 중심으로-)

  • KIM, JOON RAE
    • The Korean Society of Law and Medicine
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    • v.20 no.3
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    • pp.143-174
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    • 2019
  • Our Constitution obliges the state to protect the health of the people, and the Medical Law, which embodied Constitution, sets out in detail the matters related to open the medical institution, and one of them is to prohibit the operation of multiple medical institutions. By the way, virtually multiple medical institutions could be opened and operated because the Supreme Court had interpreted that several medical institutions could be opened if medical activities were not performed directly at the additional medical institution which was opened under the another doctor's license. However, some health care providers opened the several medical institutions with another doctor's license for the purpose of the maximization of profit, and did illegal medical cares like the unfair luring of patients, over-treatment, and commission treatment. Also, realistic problems such as the infringed health rights have arisen. Accordingly, lawmakers had come to amend the Medical Law to readjust the system of opening for medical institution so that medical personnel could not open or operate more than one medical institution for any reason. For this reason, the Constitutional Court recently declared a constitutional decision through a long period of in-depth deliberation because the constitutional petition and the adjudication on the constitutionality of statutes had been filed on whether Article 33 paragraph 8 of the revised medical law is unconstitutional. The Constitutional Court acknowledged the "justice of purpose" in view of the importance of public medical institutions, of the prevention from seduction of for-profit patients and from over-treatment, and of the fact that health care should not be the object of commercial transactions. Given the risk that medical personnel might be subject to outside capital, the concern that the holder of the medical institution's opening certificate and the actual operator may be separated, the principle that the human body and life should not be just a means, and the current system's inability to identify over-treatment, it also acknowledged the 'minimum infringement'. Furthermore, The Constitutional Court judged it is constitutional in compliance with the principle of restricting fundamental rights, such as 'balance of legal interests'. In this regard, legislative complements are needed in order to effectively prevent the for-profit management and the over-treatment the Constitutional Court is concerned about. In this regard, consumer groups actively support the need for legislation, and health care providers groups also agree on the need for legislation. Therefore, the legislators should respect the recent Constitutional Court's decision and in the near future complete the complementary legislation to reflect the people's interests.

A Descriptive Study Of School Children's Knowledge, Attitudes And Practices Regarding Smoking (중학생들의 흡연에 대한 지식, 태도, 그리고 행동에 관한 기술적 연구)

  • Park, In-Hyae
    • Research in Community and Public Health Nursing
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    • v.7 no.2
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    • pp.420-436
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    • 1996
  • The goal of this study is to explore different risk factors for smoking and look at the relationships between knowledge, attitudes, and behavioral intentions regarding smoking among schoolchildren, in order to reduce teenage smoking. To achieve this goal a self-administered questionaire regarding smoking was provided to schoolchildren in the 7th and 8th grades in one junior high school in Jerusalem. The schoolchildren were exposed to 10-12 hours of a smoking prevention intervention program. The questionaire focused primarily on the personal characteristics, social environment, knowledge, attitudes, practices, and behavioral intentions of the children. Crosstabs were performed on each variable to determine if significant associations exist among the different variables. The statistical computer, package, SPSS PC, was used to manipulate the data along with Chi-square test. The findings were as follows : About 11% of the children aged 12-14 have ever smoked or are smoking currently, and about 24.0% of those who ever smoked started smoking at the age of 10. Boys smoke more(p<.01), poorer students(by self-perception of school performance) smoke more, and those who had peers who were smokers were more likely to smoke(p<.05). The percentage of the children who reported that either father or mother smoked was about 30%, but no statistical association was found between parental smoking and children's smoking, although trends were noted in the expected direction, i.e. more smokers among children of smokers. Only 1.1% of the children intended to smoke in the future, and 98.0% of the children indicated that they can or they might be able to withstand social pressure. Seventy percent of the children demonstrated medium to high knowledge about smoking, Males, 8th graders, better students, and those without friends who smoke had higher social pressure showed more negative attitudes(p<.01). Those with non-smoking siblings showed more negative behavioral intentions regarding smoking(p<.01), and better students showed more negative behavioral intentions. Those who had higher knowledge scores showed more negative attitudes towards smoking, but not significantly so. Those who had very negative behavioral intentions showed highly significant negative attitudes towards smoking(p<.01).

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Design Strategies and Processes through the Concept of Resilience (리질리언스 개념을 통해서 본 설계 전략과 과정)

  • Choi, Hyeyoung;Seo, Young-Ai
    • Journal of the Korean Institute of Landscape Architecture
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    • v.46 no.5
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    • pp.44-58
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    • 2018
  • Cities face new challenges not only in natural disasters by climate change but also in social and economic fluctuations. With the existing simple reconstruction method, it is difficult to solve the overall problems that a city or region may face. As a new approach to cope with various changes, the concept of resilience is emerging. Resilience is also one of the themes of recent major urban design projects. Design with the concept of resilience is a new strategy that can deal with various changes of urban space, rather than a temporary trend. The purpose of this paper is to explore the design method by analyzing cases where the concept of resilience is employed. We aim to examine what kind of design strategies are needed for the resilience design and how this design process differ in character, as compared to general design projects. Cases for this study include the "Rebuild by Design" competition held in 2013 and the "Resilient by Design/Bay Area Challenge" competition held in 2017. This paper consists of literature reviews and case studies. The latter is divided into two aspects: content analysis based on the theory of resilience and characteristics of the design process. Cases are analyzed through literature reviews and process characteristics of resilience design in response to the general design process. The main categories for urban resilience used as the framework for analysis include: Urban Infrastructure, Social Dynamics, Economic Dynamics, Health and Wellbeing, Governance Networks, and Planning and Institutions. As a result, the aspects of resilience concepts considered and design strategies undertaken by each team were identified. Each team tried to connect all 6 categories to their design strategies, placing special value on the role of governance, a system that enables collaborative design and project persistency. In terms of the design process, the following characteristics were found: planning the whole project process in the pre-project phase, analyzing predictable socioeconomic risk factors in addition to physical vulnerabilities, aiming for landscape-oriented integrated design, and sustainable implementation strategies with specific operations and budget plans. This paper is meaningful to connect the concept of resilience, which has been discussed in various articles, to design strategy, and to explore the possibility of constructing a practical methodology by deriving the characteristics of the resilience design process. It remains a future task to research design strategies that apply the concept of resilience to various types of urban spaces, in addition to areas that are vulnerable to disasters.

Serum high sensitivity C-reactive protein levels in obese middle school boys (남자 중학생에서 비만과 high sensitiviy C-reactive protein의 관계)

  • Jeong, Jae-Ho;Lim, Jae-Woo;Cheon, Eun-Jeong;Ko, Kyong-Og;Lee, Young-Hyuk
    • Clinical and Experimental Pediatrics
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    • v.49 no.6
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    • pp.617-622
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    • 2006
  • Purpose : High-Sensitivity C-reactive protein(hs-CRP) has been recognized as a very useful and sensitive predictor of the future risk of myocardial infarction. But the clinical significance of hs-CRP in children remains uncertain. To confirm the existence of obesity-induced vascular inflammation and the association between metabolic syndromes and elevation of CRP in children, we investigated the relationship among CRP, obesity, blood pressure(BP), and serum lipids in schoolboys. Methods : Twenty-eight obese(BMI $29.61{\pm}3.29kg/m^2$) and 93 non-obese(BMI $18.99{\pm}2.21kg/m^2$) boys aged 14 years were examined. Serum CRP levels was measured by the high sensitive latex turbidimetric immunoassay and subjects with CRP levels below 0.3 mg/dL were adopted to avoid the influence of acute infection. Results : Obese children had significantly higher hs-CRP levels than their non-obese group($0.104{\pm}0.075$ vs. $0.054{\pm}0.005mg/dL$). In the obese group, BMI, systolic blood pressure, diastolic blood pressure, apolipoprotein B, atherogenic index, and triglyceride were significantly higher than in nonobese. The BMI, diastolic blood pressure, apolipoprotein E, atherognic index, and triglyceride showed positive correlation with log CRP by simple regression. Multiple regression analysis indicated that BMI and apolipoprotein E were strongly related to CRP. Conclusion : This study revealed that obese children tended to have higher levels of serum hsCRP, BP elevation and dyslipidemia than the control group and that BMI and apolipoprotein E were strongly related to CRP. These results indicate that obesity related metabolic syndrome can be developed in children.