• Title/Summary/Keyword: Future Projections

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The Korea Cohort Consortium: The Future of Pooling Cohort Studies

  • Lee, Sangjun;Ko, Kwang-Pil;Lee, Jung Eun;Kim, Inah;Jee, Sun Ha;Shin, Aesun;Kweon, Sun-Seog;Shin, Min-Ho;Park, Sangmin;Ryu, Seungho;Yang, Sun Young;Choi, Seung Ho;Kim, Jeongseon;Yi, Sang-Wook;Kang, Daehee;Yoo, Keun-Young;Park, Sue K.
    • Journal of Preventive Medicine and Public Health
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    • v.55 no.5
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    • pp.464-474
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    • 2022
  • Objectives: We introduced the cohort studies included in the Korean Cohort Consortium (KCC), focusing on large-scale cohort studies established in Korea with a prolonged follow-up period. Moreover, we also provided projections of the follow-up and estimates of the sample size that would be necessary for big-data analyses based on pooling established cohort studies, including population-based genomic studies. Methods: We mainly focused on the characteristics of individual cohort studies from the KCC. We developed "PROFAN", a Shiny application for projecting the follow-up period to achieve a certain number of cases when pooling established cohort studies. As examples, we projected the follow-up periods for 5000 cases of gastric cancer, 2500 cases of prostate and breast cancer, and 500 cases of non-Hodgkin lymphoma. The sample sizes for sequencing-based analyses based on a 1:1 case-control study were also calculated. Results: The KCC consisted of 8 individual cohort studies, of which 3 were community-based and 5 were health screening-based cohorts. The population-based cohort studies were mainly organized by Korean government agencies and research institutes. The projected follow-up period was at least 10 years to achieve 5000 cases based on a cohort of 0.5 million participants. The mean of the minimum to maximum sample sizes for performing sequencing analyses was 5917-72 102. Conclusions: We propose an approach to establish a large-scale consortium based on the standardization and harmonization of existing cohort studies to obtain adequate statistical power with a sufficient sample size to analyze high-risk groups or rare cancer subtypes.

Estimation of Economic Benefits Based on Appropriate Allocation of Emergency Medical Beds by Region in South Korea (지역별 응급의료병상 적정 분배에 따른 경제적 편익 추정)

  • Jeong Min Yang;Min Soo Kim;Jae Hyun Kim
    • Health Policy and Management
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    • v.34 no.1
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    • pp.17-25
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    • 2024
  • Background: This study aimed to assess the appropriate allocation of emergency medical beds across 17 provinces and presume the economic benefits associated with such allocation. Methods: To estimate the optimal allocation of emergency medical beds by province, data from the Statistics Korea's "cause of death statistics (2014-2021)," regional statistics on "area, population, gender, age," and "population projections" were utilized. The "number of emergency beds by city and district" provided by the Health Insurance Review and Assessment Service was also used. In estimating the economic benefits of preventing avoidable emergency deaths due to the expansion of emergency medical facilities, guidelines from the Korea Development Institute and the Korea Transport Institute were referenced to calculate the wage loss costs associated with emergency deaths and estimate the economic benefits. Results: The optimal ratio of emergency medical beds allocation by region was highest in Gyeonggi, Seoul, Gyeongnam, Gyeongbuk, and Busan, while Daejeon, Jeju, and Sejong showed lower ratios. Additionally, the prevention of avoidable deaths and economic benefits resulting from the increase in emergency medical facilities were highest in Gyeonggi, Seoul, Gyeongbuk, Gyeongnam, and Busan. However, when standardized by population, the prevention of avoidable deaths and economic benefits were analyzed to be highest in Gyeongbuk, Chungnam, Jeonnam, Gyeongnam, and Busan. Conclusion: The results of this study can serve as foundational data for future policy measures aimed at addressing the imbalance in the supply of emergency medical facilities across regions. Considering regional characteristics in the distribution of emergency medical facilities is expected to ultimately increase the efficiency of national finances and yield economic benefits.

Prospects of Fertilizer Demand based on Recent Consumption (최근(最近)의 비료소비면(肥料消費面)에서 본 비료수요전망(肥料需要展望))

  • Park, Young-Dae
    • Korean Journal of Soil Science and Fertilizer
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    • v.9 no.3
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    • pp.149-163
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    • 1976
  • In Korea, the ever-increasing population has become a serious problem and the decreasing of cultivated lard area per person has become a major concern. Therefore, today we are implementing a green revolution using miracle varieties which require more fertilizer. The increased use of fertilizer along with development and adoption of high yielding varieties is the key to carrying out this green revolution. Fertilizer consumption in Korea is mainly influenced by agricultural techniques, fertilizer prices and government policies for increasing food production. If there are no special change, such as a cataclysm or an exhaustion of resources, it is quite clear that the fertilizer demand will increase to the near maximum ceiling point of optimum levels for crops in the year 2000. Fertilizer demand is not the amount of fertilizer that will be used by the farmer, but the actual optimum amount of plant nutrients required for maximum production. In this report, two alternative strategies are consideded in forecasting the future feitilizer demands. Alternative I is projected by reviewing consumption amounts over the last 10 years (1966~75) in Korea. The annual rate of increase in fertilizer consumption for the last 10 years was approximately 8.7% (table 1). Plant nutrient consumption rates in later years have been more balanced, and also fertilizer consumption per total acreage is considerably higher in Korea than in other countries (table 11), consequently the rate of increase in the future is expected to decline. Looking at the long term projections, the average annual rate of increase is expected to be 7% for 1976~80, 2.5% for 1981~90, 1.5% for 1991~2000. Thus, total projected fertilizer demands are estimated at 1,208,000M/T by 1980, 1,547,000M/T by 1990, 1,795,000M/T by 2000 (table 16). Alternative II is based on projected optimum fertilizer levels for crops and on increased crop acreage. The government recommended fertilizer rate has increased by a factor of 0.99 to 5.49 over the past twelve years depending on the specific crops (table 4). Levels of fertilizer demand recommended by government (table 7) in 1976 are still low compared with actual optimum fertilizer demands for crops (table 5). Therefore, future incaeases in fertilizer usage are anticipated. Thus, total projected fertilizer demands are estimated at 1,229,000M/T by 1980, 1,493,000M/T by 1990 and 1,898,000M/T by 2000(table 16).

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SSP Climate Change Scenarios with 1km Resolution Over Korean Peninsula for Agricultural Uses (농업분야 활용을 위한 한반도 1km 격자형 SSP 기후변화 시나리오)

  • Jina Hur;Jae-Pil Cho;Sera Jo;Kyo-Moon Shim;Yong-Seok Kim;Min-Gu Kang;Chan-Sung Oh;Seung-Beom Seo;Eung-Sup Kim
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.26 no.1
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    • pp.1-30
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    • 2024
  • The international community adopts the SSP (Shared Socioeconomic Pathways) scenario as a new greenhouse gas emission pathway. As part of efforts to reflect these international trends and support for climate change adaptation measure in the agricultural sector, the National Institute of Agricultural Sciences (NAS) produced high-resolution (1 km) climate change scenarios for the Korean Peninsula based on SSP scenarios, certified as a "National Climate Change Standard Scenario" in 2022. This paper introduces SSP climate change scenario of the NAS and shows the results of the climate change projections. In order to produce future climate change scenarios, global climate data produced from 18 GCM models participating in CMIP6 were collected for the past (1985-2014) and future (2015-2100) periods, and were statistically downscaled for the Korean Peninsula using the digital climate maps with 1km resolution and the SQM method. In the end of the 21st century (2071-2100), the average annual maximum/minimum temperature of the Korean Peninsula is projected to increase by 2.6~6.1℃/2.5~6.3℃ and annual precipitation by 21.5~38.7% depending on scenarios. The increases in temperature and precipitation under the low-carbon scenario were smaller than those under high-carbon scenario. It is projected that the average wind speed and solar radiation over the analysis region will not change significantly in the end of the 21st century compared to the present. This data is expected to contribute to understanding future uncertainties due to climate change and contributing to rational decision-making for climate change adaptation.

Comparison of Digital Mammography and Digital Breast Tomosynthesis (디지털 유방촬영기기와 3차원 디지털 유방단층영상합성기기의 비교연구)

  • Kim, Ye-Seul;Park, Hye-Suk;Choi, Jae-Gu;Choi, Young-Wook;Park, Jun-Ho;Lee, Jae-Jun;Kwak, Su-Bin;Kim, Eun-Hye;Kim, Ju-Yeon;Jung, Hyun-Jung;Lee, Haeng-Hwa;Bae, Gyu-Won;Lee, Mi-Young;Kim, Hee-Joung
    • Progress in Medical Physics
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    • v.23 no.4
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    • pp.261-268
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    • 2012
  • Breast cancer is the second leading cause of women cancer death in Korea. The key for reducing disease mortality is early detection. Although digital mammography (DM) has been credited as one of the major reasons for the early detection to decrease in breast cancer mortality observed in the last 20 years, DM is far from perfect for several limitations. Digital breast tomosynthesis (DBT) is expected to overcome some inherent limitations of conventional mammography caused by overlapping of normal tissue and pathological tissue during the standard 2D projections for the improved lesion margin visibility and early breast cancer detection. In this study, we compared a DM system and DBT system acquired with different thickness of breast phantom. We acquired breast phantom data with same average glandular dose (AGD) from 1 mGy to 4 mGy under same experimental condition. The contrast, micro-calcification measurement accuracy and observer study were conducted with breast phantom images. As a result, the higher accuracy of lesion detection with DBT system compared to DM system was demonstrated in this study. Furthermore, the pain of patients caused by severe compression can be reduced with DBT system. In conclusion, the results indicated that DBT system play an important role in breast cancer detection.

Suggestions on Expanding Admission Number of Medical School (의과대학 정원 확대에 대한 제언)

  • Eun-Cheol Park
    • Health Policy and Management
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    • v.34 no.2
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    • pp.120-128
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    • 2024
  • From February to now 2024, there continues to be controversy over the expansion of admission number to medical school. Some of the controversy arises from a mix of present and future time points. In the present time point, the controversy over whether physicians are some shortages or not has various aspects. Some aspects are presented as evidence of the physician shortage and others as non-shortage. Also, the presenting evidence of shortage is being disputed, and so is the evidence of the contrary. This controversy over whether there is a shortage or not in the present time point makes it difficult to reach a consensus. In 10 years, the shortage of doctors will increase due to the rapid increase in the elderly population, so the admission number of medical schools will need to be increased. However, the increase must be such that there is minimal deterioration in the quality of medical education. More admission numbers should be allocated to medical schools with a high quality of medical education. This study suggests that large-scale medical schools increase the admission number by 20%-30%, and small-scale medical schools increase the admission number by 40%-50%, if so, the total increasing number is 760 to 1,066. If the 2,000-person increase is enforced, the quality of medical education must be carefully evaluated and the results should be reflected in adjusting the admission number of medical schools. In 20 years later, the admission number of medical schools will have to be reduced. This is because the physician supply is changing to a linear function and the physician demand (medical care demand) is changing to a quadratic function. Even if the current number is maintained, there will be an excess of doctors from 2048, so the medical school admission number must be reduced and its size will be reduced to about 2,000, a 30% reduction from the current number. Because the same reduction rate for all medical schools will result in many small-scale medical schools, the M&A (mergers and acquisitions) strategy should be considered with 40 medical schools and 12 Korean medical schools. In Korea, the main contributor to estimating physician demand is the change in population structure. Due to the rapid decrease in the total fertility rate, future population projections are uncertain. The recent rapid increase in healthcare utilization should be reexamined in the forecasting of physician demand. Since the various factors that affect the estimate of doctor supply and demand are unclear, the estimate of physician supply and demand must be continuously conducted every five years, and the Health Care Workforce Committee must be established and operated. The effects of increasing the admission number of medical schools should be evaluated and adjusted annually.

A Review of Recent Climate Trends and Causes over the Korean Peninsula (한반도 기후변화의 추세와 원인 고찰)

  • An, Soon-Il;Ha, Kyung-Ja;Seo, Kyong-Hwan;Yeh, Sang-Wook;Min, Seung-Ki;Ho, Chang-Hoi
    • Journal of Climate Change Research
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    • v.2 no.4
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    • pp.237-251
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    • 2011
  • This study presents a review on the recent climate change over the Korean peninsula, which has experienced a significant change due to the human-induced global warming more strongly than other regions. The recent measurement of carbon dioxide concentrations over the Korean peninsula shows a faster rise than the global average, and the increasing trend in surface temperature over this region is much larger than the global mean trend. Recent observational studies reporting the weakened cold extremes and intensified warm extremes over the region support consistently the increase of mean temperature. Surface vegetation greenness in spring has also progressed relatively more quickly. Summer precipitation over the Korean peninsula has increased by about 15% since 1990 compared to the previous period. This was mainly due to an increase in August. On the other hand, a slight decrease in the precipitation (about 5%) during Changma period (rainy season of the East Asian summer monsoon), was observed. The heavy rainfall amounts exhibit an increasing trend particularly since the late 1970s, and a consecutive dry-day has also increased primarily over the southern area. This indicates that the duration of precipitation events has shortened, while their intensity became stronger. During the past decades, there have been more stronger typhoons affecting the Korean peninsula with landing more preferentially over the southeastern area. Meanwhile, the urbanization effect is likely to contribute to the rapid warming, explaining about 28% of total temperature increase during the past 55 years. The impact of El Nino on seasonal climate over the Korean peninsula has been well established - winter [summer] temperatures was generally higher [lower] than normal, and summer rainfall tends to increase during El-Nino years. It is suggested that more frequent occurrence of the 'central-Pacific El-Nino' during recent decades may have induced warmer summer and fall over the Korean peninsula. In short, detection and attribution studies provided fundamental information that needed to construct more reliable projections of future climate changes, and therefore more comprehensive researches are required for better understanding of past climate variations.

On the Secret Scripture of Dragon and Tiger (Yong-Ho-Bi-Gyeol)-a Jungian Commentary (용호비결 연단술의 분석심리학적 의미)

  • Yong-Wook Shin
    • Sim-seong Yeon-gu
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    • v.33 no.2
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    • pp.141-194
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    • 2018
  • The article is about Yong-Ho-Bi-Gyeol(龍虎秘訣), which is one of the most important Taoist text in Korea written by Jeong-Ryum, a Taoist and alchemist in the Chosun Dynasty. The article deals with the alchemical and psychological meanings of Yong-Ho (龍虎, Dragon-Tiger), the way of nurturing cinnabar (修丹之道), the closing of the qi (閉氣), the method of alchemical breathing, the Dantian (丹田, cinnabar-field), and the Mysterious Female's One Opening (玄牝一竅), in addition to the brief introduction of the life of Jeong-Ryum and the bibliography of the book. The Yong-Ho (龍虎) meaning the dragon and tiger is the archetype of transformation in the form of their opposites, rooted in the psychoid system of the human psyche. The unified Yong-Ho makes Dan and the Dan, literally indicating cinnabar, has many alchemical connotations such as Mercurius, the rubedo state of the alchemical process, and the philosopher's stone. In the book, Jeong-Ryum emphasized the slow and subtle way of breathing in and out of Dantian to develop neidan (内丹, inner cinnabar or inner alchemy). The refining of neidan begins by the closing of the qi, which symbolizes the radical introversion and withdrawal of all the projections on the outer objects. The Dantian located at the lower part of the abdomen has been known to preserve jing (精), the vital essence of life, which can be refined into qi and spirit (神). In Jungian perspective, the Dantian is a mandala where an individual's mind can stay and focus at the center of psyche detached from ego and related to the Self. The long-nurtured introverted energy makes the Mysterious Female's One Opening (玄牝一竅), a pit or cavity in the transcendental space, through which the meditator can have a relationship with the great female principle of the universe. The current article has introduced the contents of the Yong-Ho-Bi-Gyeol in the perspective of analytical psychology. However, it has not dealth with the remaining topics including Taesik (胎息, embryonic breathing) and Juchenhwahu (周天火候, the great Celestial circuit firing), due to the lack of author's sufficient knowledge and experience. The unexplored areas of Yong-Ho-Bi-Gyeol will be studied in the future.