• Asian Pacific Journal of Cancer Prevention
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• 제16권16호
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• pp.6997-7002
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• 2015

Background: In cervical cancer patients it has been reported that there in a significant Ki-67/MIB-1 expression is correlated with survival in cervical cancer patients. However, the prognostic value is still not well understood. Materials and Methods: In the present meta-analysis the prognostic value of Ki-67/MIB-1 with regard to overall survival (OS) and disease-free survival (DFS) in cervical cancer was investigated. The databases of PubMed, ISI Web of Science, Cochrane Central Register of Controlled Trials, EMBASE, Science Direct and Wiley Online Library were used to identify appropriate literature. Results: In order to explore the relationship between Ki-67/MIB-1 and cervical cancer, we have included 13 studies covering 894 patients in the current meta-analysis. The effect of Ki-67/MIB-1 on OS for pooled random effects HR estimate was 1.63 (95%confidence interval (CI) 1.09-2.45; P<0.05). The pooled HR for DFS was 1.26 (95%CI 0.58-2.73; P>0.05) and the subgroup analysis indicated Ki-67/MIB1 was associated with DFS (HR=3.67, 95%CI 2.65-5.09) in Asians. Conclusions: According to this meta-analysis, Ki-67/MIB-1 has prognostic value for OS in patients suffering from cervical cancer. For better evaluation of the prognostic role of Ki-67/MIB-1 on DFS, studies with larger numbers of patients are needed to validate present findings in the future.

• Asian Pacific Journal of Cancer Prevention
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• 제13권9호
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• pp.4465-4468
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• 2012

Objective: The conclusions of published reports on the relationship between the glutathione S-transferase M3 (GSTM3) A/B gene polymorphism and the risk of lung cancer are still debated. This meta-analysis was performed to evaluate the association between GSTM3 and the risk of lung cancer. Methods: Association investigations were identified from PubMed, Embase, and Cochrane Library, and eligible studies were included and synthesized using a meta-analysis method. Results: Eight reports were included into this meta-analysis for the association of GSTM3 A/B gene polymorphism and lung cancer susceptibility, covering 1,854 patients with lung cancer and 1,926 controls. No association between the GSTM3 A/B gene polymorphism and lung cancer was found in this meta-analysis (B allele: OR = 1.25, 95% CI: 0.89-1.76, P = 0.20; BB genotype: OR = 1.53, 95% CI: 0.71-3.32, P = 0.28; AA genotype: OR = 0.85, 95% CI: 0.59-1.23, P = 0.39). Conclusions: The GSTM3 A/B gene polymorphism is not associated with lung cancer susceptibility. However, more studies on the relationship between GSTM3 A/B gene polymorphism and the risk of lung cancer should be performed in the future.

• Asian Pacific Journal of Cancer Prevention
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• 제15권19호
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• pp.8361-8366
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• 2014

This meta-analysis was performed to assess the implementation effects of clinical pathways in patients with gastrointestinal cancer. A comprehensive search was conducted in the Cochrane Library, PubMed, EMBASE, Web of Science and Chinese Biomedical Literature Database (from inception to May 2014). Selection of studies, assessing risk of bias and extracting data were performed by two reviewers independently. Outcomes were analyzed by fixed-effects and random-effects model meta-analysis and reported as mean difference (MD), standardized mean difference (SMD) and odds ratio (OR) with 95% confidence intervals (CI). The Jadad methodological approach was used to assess the quality of included studies and the meta-analysis was conducted with RevMan 5.1 software. Nine citations (eight trials) involving 642 patients were included. The aggregate results showed that a shorter average length of stay [MD = -4.0; 95% CI (-5.1, -2.8); P < 0.00001] was observed with the clinical pathways as compared with the usual care. A reduction in inpatient expenditure [SMD = -1.5; 95% CI (-2.3, -0.7); P = 0.0001] was also associated with clinical pathways, along with higher patient satisfaction [OR = 4.9; 95% CI (2.2, 10.6); P < 0.0001]. Clinical pathways could improve the quality of care in patients with gastrointestinal cancer, as evidenced by a significant reduction in average length of stay, a decrease in inpatient expenditure and an improvement in patient satisfaction. Therefore, indicators and mechanisms within clinical pathways should be a focus in the future.

• 한국CDE학회논문집
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• 제15권3호
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• pp.212-221
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• 2010

Proposed in the paper is a methodology to generate kinematic template for 3D JIG models. Recently, according to increase of the rate of automatic facility in manufacturing system, the 3D manufacturing and verification research and development have been issued. So, unlike in the past, moving 3D facilities are very various like JIGs, turn table, AS/RS worked in the automated manufacturing industry. Because 3D mesh models are used in these kinds of 3D simulation, users have to define the kinematic information manually. This 3D mesh data doesn't have parametric information and design history of the 3D model unlike the design level data. So, it is lighter than 3D design level data and more efficient to render on the 3D virtual manufacturing environment. But, when user wants to find a common axis located between the links, the parameter information of the model has to reconstruct for defining kinematic construction. It takes a long time and very repetitive to define an axis and makes a joint using 3D mesh data and it is non-intuitive task for user. This paper proposed template model that provides kinematic information of the JIG. This model is kinds of a state diagram to describe a relation between links. So, this model can be used for a kinematic template to the JIG which has a same mechanism. The template model has to be registered in the template library to use in the future, after user made the model of the specific type of the 3D JIG model.

• 교육녹색환경연구
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• 제9권3호
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• pp.49-58
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• 2010

The Ministry of educational science and technology is about to conduct its 7th &8th curriculum. However, there are some problems in achieving its goals under the current class model system in both educational and architectural. This study finds the characteristics of the arrangements and architectural planning in the departmental system - designed high schools. As a result, the arrangement was tend to be 'overall type' or 'central type' depending on the teaching-learning efficiency. Liberal arts and science&technology groups were placed close, and foreign languages and general cultural studies were arranged close as well. Importantly, there were supporting facilities such as a gymnasium, a cafeteria, a library, a computer lab, and an all-purpose-room, and this arrangement provided convenience. It is for the better learning effect and the high efficiency. It is worthy noticing that the placement and formation of individual or study space is regarded importantly. In flow planning, it seemed that it was designed to reduce the users' movement to a minimum. However, there are still some problems compared to Japan or the States, who already has an established departmental system. I think that the government should enforce its necessity of planning to schools, relevant divisions, or architects to bring it up. Furthermore, it is urgently needed a practical and future-oriented study that can forecast any changes in architectural spaces within the ever-changing teaching and learning environment in the information-oriented society.

• 정보관리학회지
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• 제22권4호통권58호
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• pp.111-128
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• 2005

최근 대학도서관은 물리적 장소로서 전통적인 도서관의 역할과 전자자원을 효율적으로 서비스 할 수 있는 가상도서관의 역할을 모두 수행해야 할 도전에 직면해 있다. 이에 대학도서관은 위기와 기회를 동시에 내포하고 있는 대학도서관의 미래를 적극적으로 설계하는 도구로서 전략적 계획을 수립하는 것이 필요하다. 본 연구는 미국, 영국, 캐나다, 호주 대학도서관의 전략적 계획의 실행 문서를 비교, 분석하여 그 내용을 형식적 요소와 내용적 요소로 구분하고 전략적 계획 문서에 포함되어야 할 최소한의 요소를 권고하였다. 아울러 UMI, OULS, UBCL, USL 등 선진 대학도서관의 최근 전략적 계획 문서의 사례를 통하여 사명과 비전, 전략 등의 내용을 구체적으로 제시하였다. 궁극적으로 본 연구는 아직 전략적 계획의 작성이 일반화되지 않은 우리나라 대학도서관에 전략적 계획 수립을 위한 방향 제시와 기초 자료를 제공하고자 하였다.

• 정보관리학회지
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• 제23권1호
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• pp.5-39
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• 2006

디자인분야 대학생들이 학업능력을 향상시키고 독립적인 전문가로 성장하기 위해서는 일반적 정보문해 교육에서 추구하는 일반적인 정보문해능력 이외에 보다 복잡하고 전문적인 정보문해능력이 요구된다. 따라서 본 연구는 국내 4개 대학교의 디자인분야 교육목표와 교육과정, 그리고 미국 디자인분야 교육 인증기관인 국립미술디자인학교협회의 디자인분야 학사학위 프로그램 기준과 지침에 대한 문헌조사를 실시하고, 문헌조사를 통해 분석된 디자인분야의 핵심 정보문해능력에 대한 검증을 위하여 디자인분야 전 문가를 대상으로 한 델파이 조사를 실시하였다. 연구결과 디자인분야는 7개 범주 26개의 핵심 정보문해능력을 공통적으로 필요로 하며, 이러한 정보문해능력들은 정보문해 교육의 시기와도 관련이 있는 것으로 분석되었다. 또한 제품디자인 등 세부전공분야별로는 보다 더 전문적인 특정 정보문해능력이 추가적으로 필요하며, 이러한 디자인분야 특정 핵심 정보문해능력 이외에 디자인분야에는 일반영역/기초능력관련 일반학문분야에 대한 정보문해능력도 필요한 것으로 분석되었다.

• 한국주거학회논문집
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• 제23권6호
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• pp.49-59
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• 2012

This study suggested a new model in consideration of long life and constructability of apartment house suggested in the former part. New model suggested the possibility of cost saving based on the idea that people trend to reject because of the recognition that the new model would cost a lot of expense which work as the barrier for the expansion and distribution at the local market so as to prepare the ground for its activation. The Study was aimed at verifying the possibility of cost saving through comparing it with the existing standard apartment house system centered on the skeleton and cladding system among the new structural design models suggested in the former part. Assuming that these existing standard both models should be changed structural design into new model system, the quantity volume, cost and construction period along with the alteration of finished materials between two models were compared altogether. Simultaneously BIM library was built for easy taking-off bill of quantity and consideration of working methodology for construction working cycle, which was translated into construction cost so as to derive the cost of the two subject systems to be counted. Through the analysis, it was concluded that new model would secure variability in the future and constructability along with shortening the construction period (29%) and achieve cost saving (13%) of construction against the those of existing model.

• 한방재활의학과학회지
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• 제28권3호
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• pp.27-38
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• 2018

Objectives The aim of this research is to analyze research trends on fracture animal experimental study in Korea. Methods For reviewing research, we constructed a key question as the effect of herbal medicine on fracture healing and selected fracture animal experimental research. We searched the following 6 databases: KoreaMed, Kmbase, Koreanstudies Information Service System (KISS), National Digital Science Library (NDSL), Korea Institute of Science and Technology Information (KISTI), Oriental Medicine Advanced Searching Integrated System (OASIS). Results A total of 283 potentially relevant studies were identified; only 12 studies were selected for reviewing research. Almost studies showed that herbal medicine had significant effect on fracture healing. Conclusions The research showed that herbal medicine could significantly stimulate fracture healing and reduced inflammation. In the future, more fracture animal experimental study should be actively conducted.

• Child Health Nursing Research
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• 제26권2호
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• pp.286-295
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• 2020

Purpose: The purpose of this study was to review studies investigating the effect of bereavement care provided for parents in the neonatal intensive care unit. Methods: We conducted a literature review of databases (MEDLINE, Embase, Cochrane Library, and CINAHL) for studies published in English and four databases (RISS, KISS, NANET, and KoreaMed) for Korean studies. The selection criteria included original articles that evaluated the parents' perceptions or responses to bereavement care provided in the neonatal intensive care unit. Of 889 articles from the initial screening, 66 articles underwent full-text review and five articles were finally selected for analysis. Results: None of the studies was conducted in Korea. Only one study used a randomized control trial design. The forms of bereavement care reviewed included a provision of a memory package, grief information, and emotional and/or social support from peers or health care providers. The effectiveness of bereavement care was measured by including grief, social support, and depression. Conclusion: Bereavement care can be considered to be beneficial for relieving grief reactions and enhancing the personal growth of bereaved parents. Future research should assess the needs of bereaved parents in Korea. Nurses may play a role in developing the bereavement care for parents.