• Journal of Korean Neurosurgical Society
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• 제63권6호
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• pp.673-680
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• 2020

The demineralized bone matrix (DBM) as the bone graft material to increase the fusion rate was widely used in spinal fusion. The current study aimed to compare the fusion rate of DBM to the fusion rate of autograft in lumbar spine fusion via meta-analysis of published literature. After systematic search, comparative studies were selected according to eligibility criteria. Checklist (risk of bias assessment tool for non-randomized study) was used to evaluate the risk of bias of the included nonrandomized controlled studies. The corresponding 95% confidence interval (95% CI) were calculated. We also used subgroup analysis to analyze the fusion rate of posterolateral lumbar fusion and lumbar interbody fusion. Eight studies were finally included in this meta-analysis. These eight studies included 581 patients. Among them, 337 patients underwent spinal fusion surgery using DBM (DBM group) and 204 patients underwent spinal fusion surgery with mainly autologous bone and without using DBM (control group). There was no significant differences of fusion rate between the two groups in posterolateral fusion analysis (risk ratio [RR], 1.03; 95% CI, 0.90-1.17; p=0.66) and interbody fusion analysis (RR, 1.13; 95% CI, 0.91-1.39; p=0.27). Based on the available evidence, the use of DBM with autograft in posterolateral lumbar spine fusion and lumbar interbody fusion showed a slightly higher fusion rate than that of autograft alone; however, there was no statistically different between two groups.

• 정보보호학회논문지
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• 제29권5호
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• pp.1007-1017
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• 2019

현재 대부분의 생체인증 시스템은 단일 생체정보를 이용하여 사용자를 인증하고 있는데, 이러한 방식은 노이즈로 인한 문제, 데이터에 대한 민감성 문제, 스푸핑, 인식률의 한계 등 많은 문제점들을 가지고 있다. 이를 해결하기 위한 방법 중 하나로 다중 생체정보를 이용하는 방법이 제시되고 있다. 다중 생체인증 시스템은 각각의 생체정보에 대해서 information fusion을 수행하여 새로운 정보를 생성한 뒤, 그 정보를 활용하여 사용자를 인증하는 방식이다. Information fusion 방법들 중에서 score-level fusion 방법을 보편적으로 많이 사용한다. 하지만 정규화 작업이 필요하다는 문제점을 갖고 있고, 데이터가 같아도 정규화 방법에 따라 인식률이 달라진다는 문제점을 갖고 있다. 이에 대한 대안으로 정규화 작업이 필요 없는 rank-level fusion 방법이 제시되고 있다. 하지만 기존의 rank-level fusion 방법들은 score-level fusion 방법보다 인식률이 낮다. 이러한 문제점을 해결하기 위해 상관계수를 이용하여 score-level fusion 방법보다 인식률이 높은 rank-level fusion 방법을 제안한다. 실험은 홍채정보(CASIA V3)와 얼굴정보(FERET V1)를 이용하여 기존의 존재하는 rank-level fusion 방법들의 인식률과 본 논문에서 제안하는 fusion 방법의 인식률을 비교하였다. 또한 score-level fusion 방법들과도 인식률을 비교하였다. 그 결과로 인식률이 약 0.3%에서 3.3%까지 향상되었다.

• Journal of Korean Neurosurgical Society
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• 제30권2호
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• pp.180-185
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• 2001

Objectives : We retrospectively studied the efficacy of anterior cervical discectomy and interbody fusion without plate fixation in degenerative cervical disease. Methods : Thirty two consecutive patients with degenerative cervical disease treated by decompression and interbody fusion(Smith-Robinson technique) without anterior cervical plating were studied for postoperative complication rate as well as the clinical and radiologic outcomes and were compared the result of ours with other reported series where the anterior cervical plating was used. Results : All cases were reviewed after average period of 13 months for the purpose of this study. There were 4 postoperative complications related to grafting. A solid fusion was obtained in all cases with single-level fusion(n=21) and 81.8 % of the cases with a two-level fusion(n=11). The overall fusion rate was 93.8 % and fusion rate per level fused was 95.3%. The clinical outcome of the patients was comparable with that in the literature, with one patient having a poor result. Comparing the result of this study with others of the anterior cervical plating, clinical outcome and fusion rate were not superior in plate fixation group in single-level fusion, but increased fusion rate and decreased graft-related complication rate were noted in multilevel fusion with plate fixation. However, the clinical outcome was not superior to noninstrumented fusion group of this study. Conclusion : These results demonstrate that anterior cervical discectomy and interbody fusion(Smith-Robinson technique) without instrumentation is safe and reliable method of single-level fusion in degenerative cervical disease. Plate fixation system doesn't seem necessary in single level fusion in degenerative cervical disease.

• Journal of Korean Neurosurgical Society
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• 제54권6호
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• pp.496-500
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• 2013

Objective : To evaluate the successful fusion rate in postmenopausal women with single-level anterior cervical discectomy and successful fusion (ACDF) and identify the significant factors related to bone successful fusion in pre- and postmenopausal women. Methods : From July 2004 to December 2010, 108 consecutive patients who underwent single-level ACDF were prospectively selected as candidates. Among these, the charts and radiological data of 39 women were reviewed retrospectively. These 39 women were divided into two groups : a premenopausal group (n=11) and a postmenopausal group (n=28). To evaluate the significant factors affecting the successful fusion rate, the following were analyzed : the presence of successful fusion, successful fusion type, age, operated level, bone mineral density, graft materials, stand-alone cage or plating with autologous iliac bone, subsidence, adjacent segment degeneration, smoking, diabetes mellitus, and renal disease. Results : The successful fusion rates of the pre- and postmenopausal groups were 90.9% and 89.2%, respectively. There was no significant difference in the successful fusion rate or successful fusion type between the two groups. In the postmenopausal group, three patients (10.8%) had successful fusion failure. In the postmenopausal group, age and subsidence significantly affected the successful fusion rate (p=0.016 and 0.011, respectively), and the incidence of subsidence in patients with a cage was higher than that in patients with a plate (p=0.030). Conclusion : Menopausal status did not significantly affect bone successful fusion in patients with single-level ACDF. However, in older women with single-level ACDF, the combination of use of a cage and subsidence may unfavorably affect successful fusion.

• Journal of Pharmaceutical Investigation
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• 제41권6호
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• pp.363-369
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• 2011

In this study, we demonstrated the release behavior of carvedilol with the content of polyvinylpyrrolidone K-30 (PVP K-30) and the effect of citric acid and fumaric acid as acidifiers on the release behavior of drug. In addition, it tries to inquire into the release behavior difference of the carvedilol according to the manufacturing method. The release behavior of the tablets was compared with Dilatrand$^{(R)}$ in the simulated gastric fluid (pH1.2). Differential scanning calorimeter (DSC), X-ray diffraction (XRD) and Fourier-transform infrared spectroscopy (FT-IR) were characterized for the physicochemical properties of the tablets. In case of mixing the carvedilol and PVP K-30, in case the ratio of the carvedilol and PVP K-30 was 1:5, the release behavior was the highest among. As well as the dissolution rate of tablets manufactured by lyophilization and rotary evaporator was higher than physical mixture. The dissolution rate of containing acidifiers was more improved. But, rather the excessive amount of the acidifier addition reduced the dissolution rate.

• Journal of Korean Neurosurgical Society
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• 제60권3호
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• pp.348-354
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• 2017

Objective : To identify and investigate differences in spinal fusion between the normal and osteopenic spine in a rat model. Methods : Female Sprague Dawley rats underwent either an ovariectomy (OVX) or sham operation and were randomized into two groups: non-OVX group and OVX group. Eight weeks after OVX, unilateral lumbar spinal fusion was performed using autologous iliac bone. Bone density (BD) was measured 2 days and 8 weeks after fusion surgery. Microcomputed tomography was used to evaluate the process of bone fusion every two weeks for 8 weeks after fusion surgery. The fusion rate, fusion process, and bone volume parameters of fusion bed were compared between the two groups. Results : BD was significantly higher in the non-OVX group than in the OVX group 2 days and 8 weeks after fusion surgery. The fusion rate in the non-OVX group was higher than that in the OVX group 8 weeks after surgery (p=0.044). The bony connection of bone fragments with transverse processes and bone formation between transverse processes in non-OVX group were significantly superior to those of OVX group from 6 weeks after fusion surgery. The compactness and bone maturation of fusion bed in non-OVX were prominent compared with the non-OVX group. Conclusion : The fusion rate in OVX group was inferior to non-OVX group at late stage after fusion surgery. Bone maturation of fusion bed in the OVX group was inferior compared with the non-OVX group. Fusion enhancement strategies at early stage may be needed to patients with osteoporosis who need spine fusion surgery.

• 정보처리학회논문지C
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• 제16C권1호
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• pp.83-90
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• 2009

무선 센서 네트워크(Wireless Sensor Network : WSN)는 자율적으로 라우팅 경로를 구성하여 물리적으로 떨어진 지역의 데이터를 수집하는 무선망이다. 본 논문은 주기적으로 수집한 모든 데이터를 하나의 기지 노드로 전달하는 convergecast 환경에서 퓨전(fusion)을 반영한 라우팅 방법을 제안한다. 지금까지 대부분의 연구는 무퓨전(no-fusion)과 전퓨전(full-fusion)의 두 경우만을 다루었다. 제안하는 Fusion rate based Spanning Tree(FST)는 임의의 퓨전율 f ($0{\leq}f{\leq}1$)에서 총 전송 에너지 비용을 줄이는 라우팅 경로를 제공 한다. FST는 무퓨전(f = 0)과 전퓨전(f = 1)의 convergecast에서 각각 최적의 토폴로지인 최소 경로 트리(Shortest Path spanning Tree : SPT)와 최소 스패닝 트리(Minimum Spanning Tree : MST)를 제공하며, 임의의 f (0 < f < 1)에 대해서도 SPT나 MST보다 우수한 토폴로지를 제공한다. 시뮬레이션은 100-노드 WSN에서 모든 f ($0{\leq}f{\leq}1$)에 대해 FST의 총 길이가 평균적으로 MST보다 약 31%, SPT보다 약 8% 절약 됨을 보여준다. 따라서 우리는 FST가 WSN에서 매우 유용한 토폴로지임을 확인하였다.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2001년도 ICCAS
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• pp.91.4-91
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• 2001

In this paper, a development of the sensor fusion algorithm for a visual control of mobile robot is presented. The output data from the visual sensor include a time-lag due to the image processing computation. The sampling rate of the visual sensor is considerably low so that it should be used with other sensors to control fast motion. The main purpose of this paper is to develop a method which constitutes a sensor fusion system to give the optimal state estimates. The proposed sensor fusion system combines the visual sensor and inertial sensor using a modified Kalman filter. A kind of multi-rate Kalman filter which treats the slow sampling rate ...

• Journal of Korean Neurosurgical Society
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• 제63권6호
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• pp.723-729
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• 2020

Objective : The use of oblique lateral interbody fusion at the L5-S1 level (OLIF51) is increasing, but no study has directly compared OLIF51 and transforaminal lumbar interbody fusion (TLIF) at the L5-S1 level. We evaluated the usefulness of OLIF51 by comparing clinical and radiologic outcomes with those of TLIF at the same L5-S1 level. Methods : We retrospectively reviewed and compared 74 patients who underwent OLIF51 (OLIF51 group) and 74 who underwent TLIF at the L5-S1 level (TLIF51 group). Clinical outcomes were assessed with the visual analogue scale for back pain and leg pain and the Oswestry Disability Index. Mean disc height (MDH), foraminal height (FH), disc angle (DA), fusion rate, and subsidence rate were measured for radiologic outcomes. Results : The OLIF51 group used significantly higher, wider, and larger-angled cages than the TLIF51 group (p<0.001). The postoperative MDH and FH were significantly greater in the OLIF51 group than in the TLIF51 group (p<0.001). The postoperative DA was significantly larger in the OLIF51 group than in the TLIF51 group by more than 10º (p<0.001). The fusion rate was 81.1% and 87.8% at postoperative 6 months in the OLIF51 and TLIF51 groups, respectively, and the TLIF51 group showed a higher fusion rate (p<0.05). The subsidence rate was 16.2% and 25.3% in the OLIF51 and TLIF51 groups, respectively, and the OLIF51 group showed a lower subsidence rate (p<0.05). Conclusion : OLIF51 was more effective for the indirect decompression of foraminal stenosis, providing strong mechanical support with a larger cage, and making a greater lordotic angle with a high-angle cage than with TLIF.

• Journal of Korean Neurosurgical Society
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• 제30권sup2호
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• pp.247-253
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• 2001

Objective : In general, to perform posterior lumbar interbody fusion(PLIF), it has been used more invasive procedure than simple discectomy. However we try to perform PLIF with TFC with smaller invasion almost same as in simple discectomy. This study is about its procedure and clinical results. Materials and Methods : The authors retrospectively analyzed 43 cases of minimally invasive PLIF with TFC from July 1998 to May 2000. Operative procedure, operative complication, change of disc height, blood loss, ambulation time, hospitalization period, clinical success rate, and bony fusion rate were analyzed. Results : 40 patients were capable to walk on the 2nd day of the post-operation. The average hospitalization period is 5.6 days. The average blood loss was 0.19L/level with no transfusion or wound drainage. The height of disc changed from 8.84mm to 13.54mm. Clinical success rate is 95% when evaluated by the Prolo's scale. The complication was delayed wound infection(2) and transient paresthesis(1). The bony fusion was shown in 17 patients (94.4%) out of 18 patients who passed one year. Conclusion : As a result of minimally invasive PLIF, pain was decreased and early ambulation and short hospitalization was possible. Complication was similar or lower than other studies, and the bony fusion rate and clinical success rate were also similar during follow-up.