Comparison of Fusion Rate between Demineralized Bone Matrix versus Autograft in Lumbar Fusion : Meta-Analysis |
Han, Sanghyun
(Department of Neurosurgery, Chungnam National University Hospital, Chungnam National University College of Medicine)
Park, Bumsoo (Department of Neurosurgery, Chungnam National University Hospital, Chungnam National University College of Medicine) Lim, Jeong-Wook (Department of Neurosurgery, Chungnam National University Hospital, Chungnam National University College of Medicine) Youm, Jin-Young (Department of Neurosurgery, Chungnam National University Hospital, Chungnam National University College of Medicine) Choi, Seoung-Won (Department of Neurosurgery, Chungnam National University Hospital, Chungnam National University College of Medicine) Kim, Dae Hwan (Department of Neurosurgery, Yonsei University College of Medicine) Ahn, Dong Ki (Department of Orthopedic Surgery, Seoul Sacred Heart General Hospital) |
1 | Bae HW, Zhao L, Kanim LE, Wong P, Delamarter RB, Dawson EG : Intervariability and intravariability of bone morphogenetic proteins in commercially available demineralized bone matrix products. Spine (Phila Pa 1976) 31 : 1299-1306; discussion 1307-1308, 2006 DOI |
2 | Cammisa FP Jr, Lowery G, Garfin SR, Geisler FH, Klara PM, McGuire RA, et al. : Two-year fusion rate equivalency between Grafton DBM gel and autograft in posterolateral spine fusion: a prospective controlled trial employing a side-by-side comparison in the same patient. Spine (Phila Pa 1976) 29 : 660-666, 2004 DOI |
3 | Chen WJ, Tsai TT, Chen LH, Niu CC, Lai PL, Fu TS, et al. : The fusion rate of calcium sulfate with local autograft bone compared with autologous iliac bone graft for instrumented short-segment spinal fusion. Spine (Phila Pa 1976) 30 : 2293-2297, 2005 DOI |
4 | Choi DJ, Ahn DK, Lee S, Park HS, Jeon YW, Yang SJ, et al. : The effect of demineralized bone matrix as a graft enhancer in posterior lumbar interbody fusion using cage and local bone chips. J Korean Soc Spine Surg 15 : 157-164, 2008 DOI |
5 | Fay LY, Chang CC, Chang HK, Tu TH, Tsai TY, Wu CL, et al. : A Hybrid dynamic stabilization and fusion system in multilevel lumbar spondylosis. Neurospine 15 : 231-241, 2018 DOI |
6 | Fischgrund JS, Mackay M, Herkowitz HN, Brower R, Montgomery DM, Kurz LT : 1997 Volvo Award winner in clinical studies. Degenerative lumbar spondylolisthesis with spinal stenosis: a prospective, randomized study comparing decompressive laminectomy and arthrodesis with and without spinal instrumentation. Spine (Phila Pa 1976) 22 : 2807-2812, 1997 DOI |
7 | France JC, Yaszemski MJ, Lauerman WC, Cain JE, Glover JM, Lawson KJ, et al. : A randomized prospective study of posterolateral lumbar fusion. Outcomes with and without pedicle screw instrumentation. Spine (Phila Pa 1976) 24 : 553-560, 1999 DOI |
8 | Kadam A, Millhouse PW, Kepler CK, Radcliff KE, Fehlings MG, Janssen ME, et al. : Bone substitutes and expanders in spine surgery: a review of their fusion efficacies. Int J Spine Surg 10 : 33, 2016 DOI |
9 | Fu TS, Wang IC, Lu ML, Hsieh MK, Chen LH, Chen WJ : The fusion rate of demineralized bone matrix compared with autogenous iliac bone graft for long multi-segment posterolateral spinal fusion Orthopedics and biomechanics. BMC Musculoskelet Disord 17 : 3, 2016 DOI |
10 | Higgins JP, Green S : Cochrane handbook for systematic reviews for interventions, ed 4. West Sussex : John Wiley & Sons Ltd, 2011 |
11 | Lin L, Chow KL, Leng Y : Study of hydroxyapatite osteoinductivity with an osteogenic differentiation of mesenchymal stem cells. J Biomed Mater Res A 89 : 326-335, 2009 |
12 | Kang J, An H, Hilibrand A, Yoon ST, Kavanagh E, Boden S : Grafton and local bone have comparable outcomes to iliac crest bone in instrumented single-level lumbar fusions. Spine (Phila Pa 1976) 37 : 1083-1091, 2012 DOI |
13 | Kornblum MB, Fischgrund JS, Herkowitz HN, Abraham DA, Berkower DL, Ditkoff JS : Degenerative lumbar spondylolisthesis with spinal stenosis: a prospective long-term study comparing fusion and pseudarthrosis. Spine (Phila Pa 1976) 29 : 726-733; discussion 733-734, 2004 DOI |
14 | Lee JH : Development of osteoconductive and osteoinductive bone healing materials. Bone Abstracts 5 : SS4.3, 2016 |
15 | Louis-Ugbo J, Murakami H, Kim HS, Minamide A, Boden SD : Evidence of osteoinduction by Grafton demineralized bone matrix in nonhuman primate spinal fusion. Spine (Phila Pa 1976) 29 : 360-366; discussion Z1, 2004 DOI |
16 | Madan S, Boeree NR : Outcome of posterior lumbar interbody fusion versus posterolateral fusion for spondylolytic spondylolisthesis. Spine (Phila Pa 1976) 27 : 1536-1542, 2002 DOI |
17 | Nam WD, Yi J : Bone union rate following instrumented posterolateral lumbar fusion: comparison between demineralized bone matrix versus hydroxyapatite. Asian Spine J 10 : 1149-1156, 2016 DOI |
18 | Martin GJ Jr, Boden SD, Titus L, Scarborough NL : New formulations of demineralized bone matrix as a more effective graft alternative in experimental posterolateral lumbar spine arthrodesis. Spine (Phila Pa 1976) 24 : 637-645, 1999 DOI |
19 | Mayo BC, Haws BE, Bohl DD, Louie PK, Hijji FY, Narain AS, et al. : Postoperative fever evaluation following lumbar fusion procedures. Neurospine 15 : 154-162, 2018 DOI |
20 | Morone MA, Boden SD : Experimental posterolateral lumbar spinal fusion with a demineralized bone matrix gel. Spine (Phila Pa 1976) 23 : 159-167, 1998 DOI |
21 | Navarro SM, Frankel WC, Haeberle HS, Ramkumar PN : Fixed and variable relationship models to define the volume-value relationship in spinal fusion surgery: a macroeconomic analysis using evidence-based thresholds. Neurospine 15 : 249-260, 2018 DOI |
22 | Oikarinen J : Experimental spinal fusion with decalcified bone matrix and deep-frozen allogeneic bone in rabbits. Clin Orthop Relat Res (162) : 210-218, 1982 |
23 | Parajon A, Alimi M, Navarro-Ramirez R, Christos P, Torres-Campa JM, Moriguchi Y, et al. : Minimally invasive transforaminal lumbar interbody fusion: meta-analysis of the fusion rates. What is the optimal graft material? Neurosurgery 81 : 958-971, 2017 DOI |
24 | Rahaman MN, Xiao W, Liu Y, Bal BS : Osteoconductive and Osteoinductive Implants Composed of Hollow Hydroxyapatite Microspheres in Narayan R, Colombo P (eds) : Advances in Bioceramics and Porous Ceramics VII: A Collection of Papers Presented at the 38th International Conference on Advanced Ceramics and Composites January 27-31, 2014 Daytona Beach, Florida. Hoboken : John Wiley & Sons, 2015, Vol 35, p65 |
25 | Schizas C, Triantafyllopoulos D, Kosmopoulos V, Tzinieris N, Stafylas K : Posterolateral lumbar spine fusion using a novel demineralized bone matrix: a controlled case pilot study. Arch Orthop Trauma Surg 128 : 621-625, 2008 DOI |
26 | Aghdasi B, Montgomery SR, Daubs MD, Wang JC : A review of demineralized bone matrices for spinal fusion: the evidence for efficacy. Surgeon 11 : 39-48, 2013 DOI |
27 | Ahn DK, Moon SH, Kim TW, Boo KH, Hong SW : Demineralized bone matrix, as a graft enhancer of auto-local bone in posterior lumbar interbody fusion. Asian Spine J 8 : 129-137, 2014 DOI |
28 | Arrington ED, Smith WJ, Chambers HG, Bucknell AL, Davino NA : Complications of iliac crest bone graft harvesting. Clin Orthop Relat Res 329 : 300-309, 1996 DOI |
29 | Bae H, Zhao L, Zhu D, Kanim LE, Wang JC, Delamarter RB : Variability across ten production lots of a single demineralized bone matrix product. J Bone Joint Surg Am 92 : 427-435, 2010 DOI |
30 | Sassard WR, Eidman DK, Gray PM, Block JE, Russo R, Russell JL, et al. : Augmenting local bone with grafton demineralized bone matrix for posterolateral spine fusion: avoiding second site autologous bone harvest. Orthopedics 23 : 1059-1065; discussion 1064-1065, 2000 DOI |
31 | St John TA, Vaccaro AR, Sah AP, Schaefer M, Berta SC, Albert T, et al. : Physical and monetary costs associated with autogenous bone graft harvesting. Am J Orthop (Belle Mead NJ) 32 : 18-23, 2003 DOI |
32 | Thalgott JS, Giuffre JM, Fritts K, Timlin M, Klezl Z : Instrumented posterolateral lumbar fusion using coralline hydroxyapatite with or without demineralized bone matrix, as an adjunct to autologous bone. Spine J 1 : 131-137, 2001 DOI |
33 | Tsutsumimoto T, Shimogata M, Yoshimura Y, Misawa H : Union versus nonunion after posterolateral lumbar fusion: a comparison of long-term surgical outcomes in patients with degenerative lumbar spondylolisthesis. Eur Spine J 17 : 1107-1112, 2008 DOI |
34 | Vaccaro AR, Stubbs HA, Block JE : Demineralized bone matrix composite grafting for posterolateral spinal fusion. Orthopedics 30 : 567-570, 2007 DOI |
35 | Ungureanu G, Chitu A, Iancu I, Kakucs C, Maior T, Florian IS : Gender differences in the self-assessment of quality of life and disability after spinal fusion for chronic low back pain at a neurosurgical center in Eastern Europe. Neurospine 15 : 261-268, 2018 DOI |
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