• The Journal of Health Technology Assessment
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• v.1 no.1
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• pp.22-26
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• 2013

Objectives: Balancing benefits and risks through the drug life cycle has been discussed for many decades. The objective of this study was to review the processes and tools currently proposed for benefit-risk assessment of medicinal drugs. It aimed to establish scientific and efficient drug safety management system based on the synthetic analysis of benefit-risk evidence. Methods: We conducted a review of exiting literatures published by regulatory agencies or initiatives. Not only quantitative methodologies but also qualitative method were compared to understand their key characteristics for the benefit and risk assessment of drugs. Results: Recently, benefit-risk assessments have more structured approaches to decision making as part of regulatory science. Regulatory agencies such as European Medicines Agency, FDA have prepared plans to apply benefit-risk assessment to regulatory decision making. Also many initiatives such as IMI (Innovative Medicine Initiative) have conducted research and published reports about benefit-risk assessment. For benefit-risk assessment, four kinds of methods are necessary. Frameworks such as BRAT (Benefit Risk Action Team) framework, PrOACT-URL provide guidance for the whole process of decision-making. Metrics are measurements of risk benefit. The estimation techniques are methods to synthesis and combine evidences from various sources. The utility survey techniques are necessary to explicit preferences of various outcome from stakeholders. Conclusion: There is the lack of widely accepted, validated model for benefit-risk assessment. Nor there is an agreement among academia, industry, and government on methods for the quantitative valuation. It is also limited by available evidence and underlying assumptions. Nevertheless, benefit-risk assessment is fundamental to improve transparency, consistency and predictability for decision making through the structured systematic approaches.

• 한국벤처창업학회:학술대회논문집
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• 2010.08a
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• pp.93-112
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• 2010

Consumers show higher interest in fishery products processed food that are effective for the personal health and good for convenience, nourishment and taste. But current domestic research for fishery products processed food is marginal. In this respect, this research systematically analyzes consumers' consumption patterns and relationship to comsumer's pursuable benefit, reference for selection, satisfaction level and purpose of purchase. This research shows results as following. Consumers consider product information the most important in reference for selection, and convinience the highest in pursuable benefit. And this research analyze influence of reference for selection and pursuable benefit on satisfaction level and purpose of purchase using demographic properties as control variables. The variables which affect satisfaction level are residential district(region), recipe, nutrient, convenience, economy and the variables affect purpose of purchase are nutrient, convenienct, satisfaction level. If this result is used to develop new products and industrialize fishery products processed food, consumer market of fishery products processed food can be expanded. And this result can be utilized as fundamental reference for sales promotion.

• Journal of Information Technology Services
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• v.13 no.2
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• pp.35-53
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• 2014

Company Social Networks (CSN) has emerged as a commonly used marketing channel. One of the most important advantages in CSN is the user's voluntary behavior as a relational performance. We classified level of voluntary behavior, as 'consumption', 'active participation', and 'creative contribution' to comprehend different relational performance of CSN. Moreover, we proposed research model to compare positive attitude and negative attitude. This study aims to investigate 'the process of user's voluntary behavior in CSN' which is causal relationship between benefits of CSN, user's attitude and voluntary behavior. Empirical results with 175 valid questionnaire data revealed that CSN benefit factors played a significant role in trust and distrust. Based on these effects, trust and distrust have different influences as level of voluntary behavior, just as proposed. For practitioners, it is crucial finding that users are more active behavior based on strong trust.

• Korean Journal of Cognitive Science
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• v.31 no.2
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• pp.25-54
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• 2020

While there is no evidence for parafoveal processing in alphabetic languages such as English and Finnish, there is some evidence that morphological information is processed in syllabic languages like Chinese. Korean writing system, Hangul, would be able to provide morphological preview benefit effects since it is an "alphabetic syllabary" which contains both alphabetic and syllabic features. This study explored morphological parafoveal preview benefit effects during reading Korean using irregular verbs, which have phonological and orthographical differences between fundamental and conjugated forms. In the Experiment, the target word was irregular conjugated form, and there were four preview conditions: identical (e.g. 구워), fundamental form (e.g. 굽다), orthographically related (e.g. 굼다), and unrelated control (e.g. 죨어). In the result of study, identical was shortest and morphological, orthographical, unrelated preview were followed. Moreover, measures of first-pass reading of morphological preview were significantly shorter than those of unrelated control preview. This results support the hypothesis of morphological preview benefit effects in Korean. The implications of the results are discussed.

• Proceedings of the KSR Conference
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• 2008.06a
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• pp.796-805
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• 2008

Safety Management of Korean railway industry has been rapidly changed into a risk-based approach adopted by developed countries since Railway Safety Act 2004, Rolling Stock Risk Assessment Guidance and its following regulations came into force. The fundamental requirements for the risk-based safety management is to carry out a systematic hazard identification and quantified risk analyses including cost-benefit analyses, but there has been rare a serious discussion over risk acceptance criteria and value of life in order to be able to judge the results of risk analyses and carry out cost-benefit analyses. This study presents the results of a review of risk acceptance criteria and value of life which may be adoped to Korean railway industry through the analyses with comparison of risk accepatnce principles and risk accepatnce criteria which have been already applied to other countries or other railway operators.

• Food Science and Industry
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• v.51 no.4
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• pp.325-333
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• 2018

If private discipline replace the strict administrative regulation, fundamental rights of protective essence can be relativized while if may be beneficial for the individual freedom. Assigning the state power to the private organization is equivalent to giving up the practice of individual liberty to the organized authority. It is important to make use of public law mechanism, particularly under the imperfect juristic system. Regarding the prohibition of prior censorship, it is necessary to consider whether it is desirable to prioritize the freedom of speech over the rest of the legal benefit. Apart from this necessity, new advertisement screening mechanism was irreversibly - and controversially - introduced for the health functional food since the unconstitutional verdict of the prior screening of advertisements. With this, the state must secure the broad order through legal regulations and norms in order to freedom of speech and other legal benefit can be harmoniously and practically guaranteed.

• IEIE Transactions on Smart Processing and Computing
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• v.4 no.2
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• pp.89-96
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• 2015

In this paper, time-frequency analysis algorithms, empirical mode decomposition and local mean decomposition, are reviewed and their applications to nonlinear and nonstationary real-world data are discussed. In addition, their generic extensions to complex domain are addressed for the analysis of multichannel data. Simulations of these algorithms on synthetic data illustrate the fundamental structure of the algorithms and how they are designed for the analysis of nonlinear and nonstationary data. Applications of the complex version of the algorithms to the synthetic data also demonstrate the benefit of the algorithms for the accurate frequency decomposition of multichannel data.

• Asia-Pacific Journal of Business
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• v.11 no.3
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• pp.273-290
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• 2020

Purpose - The purpose of this paper is to examine the buyer's right to avoid the contract under SGA and CISG. Design/methodology/approach - This paper has conducted literature reviews to analyze the right to avoid the contract of the buyer based on the comparative study. Findings - Under s. 11(3) of SGA, the breach of a condition and an intermediate which deprives the buyer substantially of the whole benefit of the contract may give rise to a right to treat the contract as repudiated. But under Art. 49 of CISG, the buyer has the right to terminate the contract where the seller's failure to performance amounts to a fundamental breach of contract. Regarding the breach of an intermediate and the breach under CISG, the buyer should take into account where the seller's breach is fundamental or not. Moreover, an anticipatory breach can give rise to a right to avoid the contract. The anticipatory breach of a condition justifies termination. The breach of an intermediate and the breach under CISG require an anticipatory fundamental breach of the contract. Under SGA, the buyer has to prove an anticipatory breach in fact but CISG does not require virtual certainty, which SGA has stricter criteria to assess an anticipatory breach. Research implications or Originality - Comparative study helps to understand the nature of provisions under SGA and CISG and suggests practical advice to choose applicable laws. SGA gives more certainty to classify a contractual term. In case of the breach of a condition including the anticipatory breach under SGA, the buyer does not have to ask how much serious the breach is. But CISG requires the fundamental breach of the contract, which means that the buyer has the more burden of proof compared with SGA.

• Korean Journal of Social Welfare
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• v.59 no.3
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• pp.75-97
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• 2007

The purpose of this article is to explore French 'minima sociaux', focusing its scheme, benefit determination rule and its level appreciation. First, on the its structure domain, French 'minima sociaux' presents the plural system in which there is eight categorical benefits and one general benefit. Il is the representation of the intention to guarantee minimum income for the dead zone people out of the social insurance application and also a historical product in different period, by different logic of benefits implementation. Second, comparing nine benefits based on the benefit determination rule, level of benefits for the poor without work ability is higher than one for the poor with work ability. Il represents one polarized perception toward for the poor according to have or not its work ability. Third, comparing level of 'minima sociaux' with relative poverty line, the level of the most 'minima sociaux' is placed under the poverty line. Nevertheless, it must not forget that 'minima sociaux' plays its role as the fundamental alternative for poverty alleviation, but not the only alternative. Fourth and finally, comparing with minimum income guarantee(SMIC in french), level of RMI benefit is estimated merely on the 50% of SMIC. We can consider that it is the result of the interaction of the complex factors, as the limited role of the state toward the minimum income guarantee for the RMI beneficiary and the intervention the logic of status instead of the logic of need, etc..

• Journal of the Korea Society of Computer and Information
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• v.4 no.2
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• pp.147-154
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• 1999

Research and Development (R&D) departments concentrate their efforts on one of two key types of research: fundamental research to discover new technology, and product development research to determine ways to use new technology or to improve upon already existing technology. Of these two types of research, the first, fundamental research, does not guarantee that successful products will develop. This type of research generally requires the investment of large sums of money without the surety of financial gain. It can, however, greatly enhance a company's image and profit potential if it can then develop a successful product from the fundamental research their scientists and engineers have done. Also, through this type of research, companies can register patents which can result in income from the sale or license of the patented technology or process to other companies. Companies place themselves at financial risk when they delve into fundamental research. For that reason, most companies concentrate their research funds and efforts on the second type of research, product development. For a product to be considered successful the company must realize some sort of benefit such as profit, increased marketshare, market recognition, or any other company-defined benefits. Both types of research require a company's consistent financial investment and planning. As the world market becomes more competitive, only those companies that can produce a product with good quality, competitive pricing, and in a timely manner will thrive. This thesis focuses on issues for developing a successful product through examining a product life cycle, a product portfolio matrix, and reactive and proactive marketing strategies.