• 제목/요약/키워드: Functions of Archives

검색결과 270건 처리시간 0.03초

후기 산업주의 디자인과 그 트렌드에 관한 연구 (A Study on the Post-Industrial Design and the Trends)

  • 윤영화
    • 디자인학연구
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    • 제17권1호
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    • pp.191-200
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    • 2004
  • After the Industrialism, long-lasting issues about Post-Industrialism have closely been associated with our daily lives. The keyword of Post-Industrialism could be regarded as Immateriality, which is represented by service, Information and knowledge. In the Post-Industrial society, the major role of Post-Industrial design trend is a mediator to deliver the immateriality to users. Additionally, the maturity of technologies and product life cycle have leaded users to the design trend that is free from the technologies and functions of products. In this context, the most powerful trend of the Post-Industrial design could be "metaphor design" and "poetic dimension". The similarity of these two styles is situated in the romanticism -reflection of symbol and metaphor. However, the appearance of Apple's iMac in 1998, poetic dimension, which uses transparent plastic and colourful, pleasurable 'blobjects' has dominated the post-industrial design trend.

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Antineoplastic Natural Productx and Analogues VIII Synthesis of some Coumarins and Their cytotoxic Activities on L1210 Cell

  • Kang, K.S.;Ahn, B.Z.
    • Archives of Pharmacal Research
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    • 제9권2호
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    • pp.115-117
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    • 1986
  • Some coumarins were sythesized for the screening of their cytotoxic activities against L1210 cell. Of the conmarins sythesized, 6, 7-dihydroxycoumarin (esculetin) and 7, 8-dihydroxycoumain (dephnetin) as coumarins with dioxygenated A-ring, and 6-acetoxy-5, 7-dimethoxycoumarin and5, 7-dimethoxy-6-hydroxycoumarin as trioxygenated ones, show considerable cytotoxic activities, ED 50 being 4. 3, 8. 8, 17.2 and 5.5 $\mu$g/ml in the same other as the substances. THe extent oxygenation of the A-ring and the positions of the oxygen functions eventually play an important role for the cytotoxic activity.

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표지로서 웹에 활용하는 아이콘 디자인 분석 (Analysis of Icon Design Used in Web as a Mark)

  • 김경조;신수길
    • 디자인학연구
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    • 제16권3호
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    • pp.143-150
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    • 2003
  • 방향이나 목적, 기준 따위를 나타내는 표지의 역할로 웹 사이트에서 활용되는 아이콘은 사용자가 정보 분류에 따른 정보, 이른바 콘텐츠를 찾는데 가장 중요한 수단이 되고 있다. 사용자는 아이콘의 시각화가 콘텐츠의 내용을 정확히 담고 있을 때 인터넷 사용의 만족을 얻게 된다. 따라서 보다 사용자가 원하는 콘텐츠를 찾는데 있어서 빠르고 편리한 기능을 수행하게 되는 아이콘의 시각화는 그 중요성이 매우 높다. 이에 본 논문은 웹 사이트에서 공통의 콘텐츠를 지칭하고 있는 아이콘의 표현방식을 조사하여 무형의 콘텐츠와 유형의 콘텐츠로 나누고 그 사례를 기호적 입장에서 분석, 유형별로 가장 적합한 시각화의 방법을 제시하였다

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Structure-Activity Relationship of Fluoroquinolone in Escherichia coli

  • Lee, Soon-Deuk;Park, Tae-Ho;Lee, Yeon-Hee
    • Archives of Pharmacal Research
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    • 제21권2호
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    • pp.106-112
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    • 1998
  • Structure-activity relationship of 20 fluoroquinolones was studied using the susceptible and 4 resistant Escherichia coli which were developed against 4 fluoroquinolones [ciprofloxacin (1), KR-10755 (6), norfloxacin (2), and ofloxacin (3)] in our laboratory. The C-7 and C-8 substituents of fluoroquinolone were important in various functions such as the inhibitory activity on DNA gyrase, permeability, and efflux. Among 20 fluoroquinolones, compounds with a 3-methyl-3,7-diazabicyclo[3.3.0]octan-1(5)-ene-7-yl substituent at the C-7 position or a chlorine substituent at the C-8 position showed a good inhibitory activity on DNA gyrase (especially a mutated DNA gyrase). Compounds with a 3,7-diazabicyclo [3.3.0]octan-1(5)-ene-7-yl substituent at the C-7 position showed good permeability in the susceptible and resistant strains, while compounds with a fluorine substituent at the C-8 position were less eff luxed from cells.

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Mixed Use Complex 디자인에 관한 연구 -업무/상업/문화오락/주거기능 복합의 사례분석을 중심으로- (A Study on the Mixed Use Complex Design)

  • 이혜진
    • 디자인학연구
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    • 제21권
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    • pp.207-217
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    • 1997
  • Mixed Use Area (Multifaceted Integration) is getting increasingly demanded since it has several merits such as preventing CBD from being emptied during night time, making daily life comfortable and utilizing the land more efficiently. However, the characteristic of Mixed Use Area -as advantages of it-, which is that it combines residence, retail, office, cultural, entertainment facilities altogether could be regarded as a weakness when it is viewed from each functions' original purposes such as residential and retail areas'. Accordingly, it is needed to do basic research and develop design guidelines of the Mixed Use Area to prepare its another take-off. The purpose of this research is to study theoretical background of Mixed Use Area's birth, understand its status quo by examining examples overseas and presented possible standardized ways of developing it.

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A Color Coordination Support System based on Color Image

  • Lee Ji-Hyun;Qian Wei
    • 디자인학연구
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    • 제19권3호
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    • pp.155-166
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    • 2006
  • Color selection plays a vitally important role in creating impressions of individuals or companies. This is largely because colors have sensibility aspects, which relate, in part, to images and, in part, to associations. Based on theories of color harmony and sensibility ergonomics, we have developed quantitative and systematic metrics for color images. In this paper, we suggest a color coordinate system that supports color analysis and color harmony functions using color images, which can be captured by corresponding adjectival words. We focus on a prototype system for graphical logo design to exemplify our concepts. The system can be applied to a wide variety of design domains.

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Malar Relocation with Reverse-L Osteotomy and Autogenous Bone Graft

  • Yoon, Se Hoon;Jeong, Euicheol;Chung, Jee Hyeok
    • 대한두개안면성형외과학회지
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    • 제18권4호
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    • pp.264-268
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    • 2017
  • The zygomaticomaxillary complex (ZMC) functions as a buttress for the face and is the cornerstone to a person's aesthetic appearance, by both setting the midfacial width and providing prominence to the cheek. Malar deficiency is often acquired by blunt injury incurred in a traumatic accident, resulting in ZMC fracture. A 48-year-old male patient presented a right ZMC fracture after contusion injury by a baseball. He only received conservative management and later he suffered discomfort during mouth opening at the moment of mastication, due to trismus involving the temporomandibular joint. In the current case, we describe a surgical technique, by which the malar body is shifted anteriorly and laterally after combined oblique-vertical osteotomy. The technique presented, eventually restored the former aesthetic position of the malar complex and symmetry, and, moreover, improved mastication function.

Pharmacological Activities of a New Glycosaminoglycan, Acharan Sulfate Isolated from the Giant African Snail Achatina fulica

  • Shim, Jin-Young;Lee, Yeon-Sil;Jung, Sang-Hoon;Choi, Hyung-Seok;Shin, Kuk-Hyun;Kim, Yeong-Shik
    • Archives of Pharmacal Research
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    • 제25권6호
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    • pp.889-894
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    • 2002
  • Acharan sulfate (AS) is a glycosaminoglycan (GAG) prepared from the giant African snail, Achatina fulica. In this study, some biological activities of AS were evaluated on the basis of structural similarities to heparin/heparan sulfate and the biological functions of GAGs. We demonstrated that it exhibited strong immunostimulating activities as measured by carbon clearance test in mice and in vivo phagocytosis. It also exhibited a significant hypoglycemic activity in epinephrine (EP)-induced hyperglycemia as well as antifatigue effects by weight-loaded forced swimming test. And it showed hypolipidemic activities in cholesterol-rich mixture induced hyperlipidemia in rats. The above results indicate that AS has diverse biological activities and suggest therapeutically important target molecules.

P62 and the Sequestosome, a Novel Mechanism for Protein Metabolism

  • Shin, Jae-Kyoon
    • Archives of Pharmacal Research
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    • 제21권6호
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    • pp.629-633
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    • 1998
  • In addition to selecting proteins for degradation by the 26S proteasome, ubiqitination appears to serve other regulatory functions, including for endosomal/lysosomal targeting, protein translocation, and enzyme modification. Currently, little is known how multiubiquitin chains are recognized by these cellular mechanisms. Within the 26S proteasome, one subunit (Mcb1/S5a) has been identified that has affinity for multiubiquitin chains and may function as a ubiquitin receptor. We recently found that a non-proteasomal protein p62 also preferentially binds multiubiquitin chains and forms a novel cytoplasmic structure "sequestosome" which serves as a storage place for ubiquitinated proteins. In the present manuscript, the role and regulation of p62 in relation to the sequestosomal function will be reviewed.

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함평사건희생자유족회의 소장 기록물 분류표 개발에 관한 연구 (A Study on the Development of the Classification Table of the Records of the Association for the Bereaved Families of the Hampyeong Massacre Victims)

  • 김유선;이명규
    • 한국기록관리학회지
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    • 제18권1호
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    • pp.155-175
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    • 2018
  • 이 연구의 목적은 함평사건희생자유족회의 소장 기록물에 대한 분류체계를 마련하는 데에 있다. 이에 따라 기록물의 맥락을 기능적 출처주의를 통해 구현하며, 기록물을 효과적으로 활용할 수 있도록 유형별 특성과 생산시기별 특성을 반영한 분류표를 제시하였다. 기능분류체계 개발 방법론인 DIRKS를 사용하여 함평사건희생자유족회의 업무분석을 수행함으로써, 업무기능-업무활동-처리행위로 이어지는 업무분류표를 도출한다. 함평사건희생자유족회 소장 기록물을 유형과 생산시기별 특성을 고려하여 그 범주를 결정한다. 기록물 맵핑은 업무분류표에 해당하는 업무분류체계에 1차적으로 실행하고, 2차적으로는 업무분류에 유형분류와 시대분류를 접목한 다중분류체계에 맵핑한다. 업무주제-업무활동-처리행위-유형-시대의 형태로 이어지는 기록물 분류표를 도출한다.