• Title/Summary/Keyword: Functional levels

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Characteristics of Pinitol as a Functional Food Biomaterial (건강기능성 식품소재로서 pinitol의 특성)

  • Son, Min-Sik;Seo, Myung-Seon;Lee, Sang-Han
    • Journal of Life Science
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    • v.19 no.1
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    • pp.147-151
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    • 2009
  • D-pinitol, another chemical structure of 3-O-methyl-D-chiro-inositol, is an important insulin-sensitizer. The purpose of this review is to examine the characteristics of pinitol and other analogs as functional food biomaterials which were well known to reduce blood glucose levels. Pinitol can be converted to chiro-inositol in normal humans, while diabetic patients can not use the molecule, resulting in exhibiting low level of chiro-inositol in their urine. Recently, it is reported that pinitol can trigger phospholipase C/D, thus the rate of glucose metabolism accelerates to use as fuel for human body. To not only reduce insulin resistance of diabetic patients, but also alleviate the symptoms of diabetes, obesity, and muscle contraction, pinitol and its dietary supplementation is needed.

Manufacture of Hanji Using Tencel Fiber (텐셀섬유를 활용한 한지의 제조)

  • 민춘기;조중연;신준섭;류운형
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.33 no.4
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    • pp.35-41
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    • 2001
  • A newly developed functional fiber for textile, Tencel, which is known to have some advantages over wood fiber such as fibrillation, absorbency and so on, was examined to see the possibility of a raw material for hanji. Hanji was manufactured by the conventional handmade method using Tencel of three different fiber lengths with three different levels of mixing ratio of Tencel and paper mullberry fiber, and their physical and calligraphic properties were evaluated and compared with one another. It was needed to develop more efficient beating methods than conventional one such as valley beating for Tencel to be used effectively as a raw material for hanji. It was found out by image analysis that the calligraphic properties of hanji could be improved by mixing of 10 to 20% of Tencel of relatively short-length fiber with paper mulberry.

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Effects of Hot Water Extract of Chaga Mushroom on the Proliferation and Cytokines Production of Mouse Splenocytes In Vitro (차가버섯 열수 추출물이 비장세포 증식능과 Cytokine 생성능에 미치는 영향)

  • Kim, Po-Ra;Ko, Suk-Kyung;Pyo, Myoung-Yun
    • YAKHAK HOEJI
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    • v.54 no.3
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    • pp.187-191
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    • 2010
  • Chaga mushroom (Inonotus obliquus) has been identified to have various biological activities. This study was performed to investigate the potential of chaga mushroom as a immunomodulating functional food. When mouse splenocytes were exposed to various concentration of hot water extracts of chaga mushroom (IOE) with mitogens (Con A, LPS), splenocytes proliferation was significantly increased. Also, IFN-$\gamma$ and IL-4 levels were significantly enhanced. Therefore, our results suggest that chaga mushroom may have the potential of being an immunomodulating functional food.

Computational Study of the Molecular Structure, Vibrational Spectra and Energetics of the OIO Cation

  • Lee, Sang-Yeon
    • Bulletin of the Korean Chemical Society
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    • v.25 no.12
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    • pp.1855-1858
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    • 2004
  • Molecular geometries for the cationic and neutral species of OXO (X=Cl, Br, and I) are optimized using the Hartree-Fock (HF) theory, the second order Moller-Plesset perturbation theory (MP2), the density functional theory with the B3LYP hybrid functional (B3LYP), and the coupled cluster theory using single and double excitation with a perturbational treatment of triplet excitation (CCSD[T]) methods, with two basis sets of triple zeta plus polarization quality. The single point calculations for these species are performed at the CCSD(T,Full) level. The harmonic vibrational frequencies for these species are calculated at the HF, MP2, B3LYP and CCSD(T) levels. The adiabatic ionization potential for OIO is calculated to be 936.7 kJ/mol at the CCSD(T,Full) level and the correct value is estimated to be around 945.4 kJ/mol.

Effect of Basis Set Superposition Error on the MP2 Relative Energies of Gold Cluster Au6

  • Kim, Kyoung-Hoon;Kim, Jong-Chan;Han, Young-Kyu
    • Bulletin of the Korean Chemical Society
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    • v.30 no.4
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    • pp.794-796
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    • 2009
  • We have studied the structures and stabilities of Au6 to explore the origin of the large discrepancy between relative energies obtained from the density functional theory (DFT) and ab initio correlated levels of theory. The MP2 methods significantly overestimate the stability of the non-planar isomer when the double-$\zeta$ polarization quality of basis sets, such as LANL2DZ+1f and CEP31G+1f, are used. However, we show that such preference for the non-planar structure at the MP2 level mainly originates from the large basis set superposition error.

Efficacy of Korean Red Ginseng in the Treatment of Atopic Dermatitis

  • Lee, Kyung-Goo;Son, Sang-Wook
    • Journal of Ginseng Research
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    • v.35 no.2
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    • pp.149-154
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    • 2011
  • In order to determine the efficacy of functional foods, objective measurement of the severity of atopic dermatitis (AD) after taking foods is important. The aim of this study was to conduct an objective evaluation of whether Korean red ginseng (KRG) might be helpful for improvement of skin condition and serum IgE in patients with AD. Thirty atopic patients (18 females and 12 males) participated in this study. Patients took KRG for 16 weeks. Bioengineering methods, including the corneometer and evaporimeter, were used at the start of the study and after 8 weeks and 16 weeks. In addition, we assessed serum IgE levels and the severity scoring of the atopic dermatitis (SCORAD) index. Transepidermal water loss and skin hydration showed significant improvement after 16 weeks. A significant decrease in the SCORAD index, as well as in serum IgE level, was observed after 16 weeks. Our results demonstrated that KRG may be helpful as a functional food for patients with AD.

Effects of Pear (Pyrus pyrifolia) Methanol Extracts on the Proliferation and the Cytokines Production of Mouse Splenocytes (배(梨)의 메탄올 추출물이 마우스의 비장세포 증식능과 Cytokine 생성능에 미치는 영향)

  • Hwang Yoo-Kyung;Pyo Myoung-Yun
    • YAKHAK HOEJI
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    • v.49 no.1
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    • pp.25-29
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    • 2005
  • This study was performed to investigate the potential of pear (Pyrus pyrifolia) as a immune-modulating functional food by assay of splenocytes proliferation and induction of cytokines (IFN-${\gamma}$, IL-4) in vitro. When mouse splenocytes were exposed to various concentration (0.16, 0.31, 0.63, 1.25, 2.50 mg/ml) of pear methanol extracts (P-M) without mitogens, splenocytes proliferation (SP) was significantly increased. Also, SP to mitogens, concanavalin A (Con A) and lipopolysaccharide (LPS) were significantly increased by P-M when compared with controls. When splenocytes were cultured with P-M in the presence of Con A, cytokine (IFN-${\gamma}$, IL-4) levels in culture supernatant were significantly enhanced in a dose-dependent manner except 2.5 mg/ml when compared with control group. Therefore, our study suggest that the pear has the potential of being an immune-modulating functional food.

Safety Levels Apportionment in Railway System

  • Rafrafi, Meriem;El Koursi, El Miloudi;Bourdeaud'Huy, Thomas
    • International Journal of Railway
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    • v.1 no.4
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    • pp.157-168
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    • 2008
  • The creation of a single European rail transport market it is important to increase confidence between the actors on the market and between member states who shall ensure that railway safety is generally maintained and, where reasonably practicable, continuously improved. For this purpose the European railway safety directive introduces a mechanism to adopt a Common Safety Targets (CST) expressed in risk acceptance criteria for individuals and for society. This paper focuses on the apportionment of safety targets for European railway system. We develop a generic approach based on the Functional Hazard Analysis (FHA), to analyse the safety of railway systems for a unified European network and to comply with the CSTs required by the European railway Safety Directive. We suggest to combine the FHA technique with the functional railway architecture to allocate the safety targets to the railway functions.

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Vibrational Analysis of Dopamine Neutral Bae based on Density Functional Force Field

  • Park, Seon Gyeong;Lee, Nam Su;Lee, Sang Ho
    • Bulletin of the Korean Chemical Society
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    • v.21 no.10
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    • pp.1035-1038
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    • 2000
  • Vibrational properties of dopamine neutral species in powder state have been studied by means of the normal mode analysis based on the force constants obtained from the density functional calculation at B3LYP level and the results of Fourier trans form Raman and infrared spectroscopic measurements. Ab initio calculation at MP2 level shows that the trans conformer of dopamine has higher electronic energy about 1.4 kcal/mol than those of the gauche+ and the gauche-conformers, and two gauche conformers have almost the same energies. Free energies calculated at HF and B3LYP levels show very similar values for three conformers within 0.3 kcal/mol. Empirical force field has been constructed from force constants of three conformers, and refined upon ex-perimental Raman spectrum of dopamine to rigorous values. The major species of dopamine neutral base in the powder state is considered a trans conformer as shown in the crystallographic study of dopamine cationic salt.

Security Evaluation Criteria for Firewalls in Kirea

  • Lee, Cheol-Won;Hong, Ki-Yoong;Kim, Hak-Beom;Oh, Kyeong-Hee;Kwon, Hyun-Jo;Sim, Joo-Geol
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.8 no.3
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    • pp.63-78
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    • 1998
  • Recently, to use the evaluated firewall is recognized as a solution to achieve the security and reliability for government and organizarions in Korea. Results of firewall evaluation using ITSEC(Information Technology Security Evaluation Criteria) and CCPP(Common Criteria Protection Peofile)have been announced. Because there are problems to apply ITSECor CCPP for the firewall evaluation in korea environment, korea government and korea Information security Agency (KISA) decided to develop our own security dvaluation critrtia fir firewalls.As a result of the efforts, Korea firewall security evaluation criteria has been published on Feb. 1998. In this paper, we introduce Korea security evaluation criteria for firewalls. The ceiteria consists of functional and assurance requirements that are compatible with CC Evaluation Assurance Levels(EALs)