• 제어로봇시스템학회논문지
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• 제7권8호
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• pp.689-696
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• 2001

Large-scale Multi-disciplinary Systems(LMS) such as transportation, aerospace, defense etc. are complex systems in which there are many subsystems, interfaces, functions and demanding performance requirements. Because many contractors participate in the development, it is necessary to apply methods of sharing common objectives and communicating design status effectively among all of the stakeholders. The processes and methods of systems engineering which includes system requirement analysis; functional analysis; architecting; system analysis; interface control; and system specification development provide a success-oriented disciplined approach to the project. This paper shows not only the methodology and the results of model-based systems engineering to Automated Guided Transit(AGT) system as one of LMS systems, but also propose the extension of the model-based tool to help manage a project by linking WBS (Work Breakdown Structure), work organization, and PBS (Product Breakdown Structure). In performing the model-based functional analysis, the focus was on the operation concept of an example rail system at the top-level and the propulsion/braking function, a key function of the modern automated rail system. The model-based behavior analysis approach that applies a discrete-event simulation method facilitates the system functional definition and the test and verification activities. The first application of computer-aided tool, RDD-100, in the railway industry demonstrates the capability to model product design knowledge and decisions concerning key issues such as the rationale for architecting the top-level system. The model-based product design knowledge will be essential in integrating the follow-on life-cycle phase activities. production through operation and support, over the life of the AGT system. Additionally, when a new generation train system is required, the reuse of the model-based database can increase the system design productivity and effectiveness significantly.

• 턱관절균형의학회지
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• 제5권sup호
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• pp.1-5
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• 2015

Objectives: The aim of this study was to review main symptoms of outpatient in Lee young Jun clinics who developed the functional cerebrospinal therapy and to investigate the therapeutic effects on one time application of functional cerebrospinal therapy (FCST). Methods: Patients who visited at least twice at an oriental medical clinic and treated with FCST were included. They were asked to write 216 numeric rating scale (NRS)-based questionnaire about degree of various symptoms at each visit. Prevalence and degree decrease of all reported symptoms were analyzed. Results: Total of 744 outpatients were included. There were fourteen symptoms of which more than half of all patients commonly complained. All symptoms were significantly reduced after one administration of FCST. About four to seven percent of patients reported at least five-point reduction on NRS in each symptom after FCST. Conclusions: FCST might have potential immediate effect on not only TMJ related symptoms, but also diverse kinds of pain, psychological symptoms, and fatigue-related symptoms.

• 대한통합의학회지
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• 제9권2호
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• pp.93-103
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• 2021

Purpose : This study aimed to investigate the effect of trunk postural stability maintained wearing a spiral elastic band on the upper extremity function of patients with stroke who undertook a functional activity program and to provide fundamental data useful for the application of therapeutic interventions in the clinical environment of occupational therapy. Methods : The research subjects included 16 patients with stroke who were evenly divided into an experimental group and a control group. The eight-week intervention consisted of a functional activity program aimed at improving the function of the affected-side upper extremity. The experimental group performed the functional activity program while maintaining a stable trunk posture by wearing a spiral elastic band. The control group followed the program without wearing the band. Upper extremity function was assessed before and after the intervention using a manual function test (MFT) and a motor activity log (MAL), and the effectiveness on the upper extremity function of the affected side was confirmed. Results : First, in the within-group comparison of the upper extremity function scores before and after the intervention, the experimental group showed a statistically significant difference in the MFT and MAL assessment(p<.05). The control group showed a statistically significant difference in the MAL assessment(p<.05). Second, in the between-group comparison of the change in scores after the intervention, a statistically significant difference was observed between the two groups in all assessments(p<.05). Conclusion : This study confirmed the positive effect on upper extremity function of trunk stabilization posture using a spiral elastic band. The results could be useful when implementing a task-oriented training program in the clinical environment of occupational therapy in the future, as application of the training while maintaining trunk postural stability by wearing a spiral elastic band could be more effective for improving the upper extremity function of patients with stroke.

• 대한정형도수물리치료학회지
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• 제28권1호
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• pp.19-27
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• 2022

Background: This study investigated the effects of a single-leg hopping test and Q-angle when applying Mulligan taping, flossing bands, and a combination of Mulligan taping and flossing bands to chronic ankle instability (CAI) patients. Methods: The subjects of the study were 68 patients with chronic ankle instability, randomly divided into three groups receiving the following treatments: Mulligan taping (n=22), flossing bands (n=23), and a combination of Mulligan taping and flossing bands (n=23). The immediate effects of the treatments were evaluated using the single-leg hopping test and Q-angle measurement for functional movement before and after the intervention. Results: All three groups showed significant improvements in the single-leg hopping test after the intervention, and there was a significant difference between the performance of the simultaneous application group and the Mulligan taping group (p<.01). As a result of the post-hoc test, there was a significant difference in the simultaneous application group than in the mulligan taping group (p<.01). When measuring the Q-angle change during the activity of descending stairs, there was also a significant effect in all three groups, with no significant differences when comparing the changes between groups (p>.05). Conclusions: In conclusion, Mulligan taping and flossing bands were confirmed as effective interventions for the functional movement of the lower extremities in patients with CAI. This study can provide basic data on the effectiveness of interventions in patients with CAI.

• 대한한방내과학회지
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• 제32권4호
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• pp.584-598
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• 2011

Objectives : Functional dyspepsia is a type of disease characterized by bothersome postprandial fullness, early satiation, epigastric pain and burning without structural gastrointestinal disease. The aim of this study was to analyze the characteristics of functional dyspepsia patients and evaluate changes in symptoms, quality of life, and electrogastrography parameters before and after oriental medical interventions. Methods : We recruited forty-six functional dyspepsia patients who visited gastroenterology clinic in the oriental medicine hospital of Kyung Hee University between November 2009 and February 2011. Patients were assessed for their frequency of dyspepsia (based on short form-Leeds Dyspepsia Questionnaire: SF-LDQ), quality of life (based on functional dyspepsia-related quality of life questionnaire: FD-QoL), gastric motility (based on electrogastrography: EGG) on the first visit. Then, the effect of oriental medical interventions was evaluated using EGG on the second visit. Results : The majority of patients had symptoms of nausea and indigestion. The largest decrease in EGG parameters was found in the indigestion group. The frequency of regurgitation and postprandial EGG power % bradygastria showed a significant correlation. Also, significant correlations were found between some items of FD-QoL and some EGG parameters. Compared to the EGG parameters before oriental medical interventions, some parameters after treatment had positive results, implying the improvement of gastric motility disorder. We also found improvement of EGG parameters in both digestant medicinal group and digestant combined with qi-tonifying medicinal group. Conclusions : The results of this study suggest that clinical application of EGG can be an objective diagnostic tool in functional dyspepsia patients visiting oriental medical hospital.

• BMB Reports
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• 제31권5호
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• pp.459-467
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• 1998

A new set of functional group interaction energy descriptors relevant to the ACE (Angiotensin-Converting Enzyme) inhibitory peptide, QSAR (Quantitative Structure Activity Relationships), is presented. The functional group interaction energies approximate the charged interactions and distances between functional groups in molecules. The effective energies of the computationally derived geometries are useful parameters for deriving 3D-QSAR models, especially in the absence of experimentally known active site conformation. ACE is a regulatory zinc protease in the renin-angiotensin system. Therapeutic inhibition of this enzyme has proven to be a very effective treatment for the management of hypertension. The non bond interaction energy values among functional groups of six-feature of ACE inhibitory peptides were used as descriptor terms and analyzed for multivariate correlation with ACE inhibition activity. The functional group interaction energy descriptors used in the regression analysis were obtained by a series of inhibitor structures derived from molecular mechanics and semi-empirical calculations. The descriptors calculated using electrostatic and steric fields from the precisely defined functional group were sufficient to explain the biological activity of inhibitor. Application of the descriptors to the inhibition of ACE indicates that the derived QSAR has good predicting ability and provides insight into the mechanism of enzyme inhibition. The method, functional group interaction energy analysis, is expected to be applicable to predict enzyme inhibitory activity of the rationally designed inhibitors.

• 소프트웨어공학소사이어티 논문지
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• 제29권1호
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• pp.7-12
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• 2020

최근 기능 안전에 대한 관심이 높아짐에 따라 다양한 산업 분야에서 기능 안전 표준의 적용이 요구되고 있다. 기능 안전 표준은 시스템의 오작동을 방지하기 위해 필요한 기능 안전 관련 활동들을 정의한 문서이다. 이 표준에 정의된 모든 활동들은 시스템의 위험 분석 및 평가를 통해 산출된 등급 분류 결과에 따라 차등적으로 요구된다. 국내 무기체계 분야에는 방위사업청에서 발간한 무기체계 소프트웨어 개발 및 관리 매뉴얼이 존재한다. 이 매뉴얼은 기능 안전 관련 활동으로 소프트웨어 정적 및 동적 분석 활동을 요구한다. 하지만 해당 매뉴얼에는 선행 활동으로 요구되는 위험 분석 및 평가를 통한 등급 분류 활동 관련 내용이 구체적으로 언급되고 있지 않다. 따라서 본 연구에서는 대표적인 기능 안전 표준들을 기반으로 무기체계 소프트웨어 개발 및 관리 매뉴얼의 문제점을 분석하고 이에 대한 개선 방안을 제시하도록 한다.

• Bulletin of the Korean Chemical Society
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• 제27권11호
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• pp.1769-1774
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• 2006

A new liquid chromatographic chiral stationary phase based on (2S,3S)-O,O'-bis-(10-undecenoyl)-N,N'-bis-(3,5-dinitrobenzoyl)-2,3-diamino-1,4-butandiol was prepared starting from (2R,3R)-1,4-bis(benzyloxy)-2,3-butanediol. The new chiral stationary phase was applied to the resolution of racemic anilide derivatives of N-acetyl-a-amino acids, 1,1'-bi-2-naphthol and 3,3'-diaryl-1,1'-bi-2-naphthols. The CSP was also applied to the resolution of some chiral drugs including a diuretic, bendroflumethiazide, and non-steroidal anti-inflammatory agents such naproxen and alminoprofen. In every case, the chiral recognition efficiency of the new CSP was quite excellent.

• 대한정형도수물리치료학회지
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• 제28권1호
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• pp.9-17
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• 2022

Background: Functional massage is a therapeutic massage that incorporates joint motion in non-end-range to reduce pain and improve range of motion (ROM) in patients. This study was aimed at investigating the immediate effect of functional massage on pain, range of motion, balance ability and, gait speed of patients having undergone total hip replacement. Methods: Twenty patients were treated by one participating orthopedic manual physical therapist and randomly assigned to the control group (n=10) or the experimental group (n=10). To treat patients of each group, functional massage and range of motion exercises were used. The experimental group received a functional massage and the control group received range of motion exercise for minutes for one session. The visual analog scale was used for pain assessment. Balance ability was measured using a timed up and go test and a one-leg standing test for patients. The 10-meter walk test was used for the measurement of gait speed assessment of patients. Results: Significant improvements were observed in terms of balance ability (p<.05), gait speed (p<.05), and ROM (p<.05) after functional massage. There was no significant inter-group difference (p>.05). Conclusion: Application of the functional massage showed that statistically significant improvements in ROM, gait speed, and balance ability after a single treatment session. This technique may be a useful treatment in patients having undergone total hip replacement.

• 대한물리치료과학회지
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• 제31권1호
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• pp.1-15
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• 2024

Background: This study was conducted to apply active release techniques to male youth basketball players to help improve physical development and damage prevention and improve performance through improved balance and functional movement. Design: Randomized control trial. Methods: The subjects included 33 youth basketball players who were randomly assigned to the experimental group (n=17) and the control group (n=16). For the experimental group, the active release technique was applied to the hip muscles, calf muscles, posterior thigh muscles based on the distribution of injuries surveyed in youth basketball players in the Korean Basksetball League. The Y-balance test and the functional reach test (FRT) were used to assess balance and the Functional Movement Screen (FMS) was used to assess functional movement. Interventions were conducted twice a week for 4 weeks at 40 minutes per session. The experimental group was the active release technique group, and static stretching, a common exercise therapy technique, and self-myofascial release using a foam roller were applied for 20 minutes. The control group received general exercise therapy and placebo active release technique. The placebo active release technique applies pressure only. results:The experimental group showed a greater improvement in balance, as evidenced by the FRT, compared to the control group, which received general exercise treatment. However, there was no statistically significant difference in improvement between the 2 groups. In the case of the experimental group, the difference in the Y balance test before and after the intervention was larger than that of the control group, but there was no statistically significant difference. Significant improvement was found in functional movement, as evidence by the FMS, for the trunk stability test (p < 0.05), in-line lunge test (p < 0.05), rotational stability test (p < 0.05), total score (p < 0.05). Conclusion: In this study, the active release technique improved the balance and functional movement of young basketball players more than general exercise therapy. The application of the active release technique is therefore expected to assist in physical development, prevent damage, and improve the performance of youth basketball players.