• 한국습지학회지
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• 제25권4호
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• pp.386-393
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• 2023

최근 들어서 국내의 해양치유산업 활성화를 위한 해양치유자원의 효능·효과에 관한 연구개발이 진행 중에 있다. 본 연구는 해양치유자원으로서 잘 알려진 머드 물질에 대한 효능성분 분석을 통해 활용·관리 기준을 제시하였다. 머드물질 시료는 국내 갯벌에서 채취되었으며, 모래질, 실트질 및 점토질 함량은 각각 평균 7.87%, 74.95% 및 17.17%로 머드(실트+점토)의 평균 함량이 90% 이상이었다. 효능성분은 SiO2(68.4%)성분이 가장 높으며, 다음으로 Al₂O₃(13.3%)>Fe₂O₃(4.0%)>K₂O(2.9%)>Na₂O(2.3%)>MgO(1.6%)>CaO(1.0%)>TiO₂(0.7%) 순으로 평균함량이 높았다. 효능성분 분석을 바탕으로 기능성을 나타내는 성분(기능 성분)을 Si, Al, Fe, K, Na, Mg, Ca를 선정하였으며, 또한 품질관리를 목적으로 정하는 성분(지표 성분)은 효능을 가진 성분 중 함량이 높은 K, Mg, Ca로 결정하였다. 결과적으로 기존 문헌을 참고하여 국내 갯벌머드자원이 해양치유자원으로서 활용·관리되기 위해서는 원재료의 머드함량이 70.0% 이상 그리고 지표 성분인 K₂O+MgO+CaO의 합이 5.0% 이상을 기준으로 제시하였다.

• 대한통합의학회지
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• 제9권3호
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• pp.19-35
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• 2021

Purpose : Recently, there has been a growing social interest in aging well. Consequently, wellness tourism has begun to attract attention. However, no studies on whether wellness tourism has any objective health benefits have been carried out yet. In this study, we assess the health benefits as well as the degree of improvement in health of a wellness tourism program. Methods : The study involved 30 adults over the age of 19 who live in the Gyeongsangnam-do region. Participants were evaluated on health indicator before and after participating in wellness tourism program. Participants took heart rate variability (HRV) test, and LFT, RFT, CBC, FBS HbA1C, and CRP test were conducted before and after the tour. Additionally, a survey was conducted before and after the program, and participant satisfaction was evaluated. Statistical differences in the tests conducted before and after the program were analyzed using a design t-test, a Wilcoxon signed-rank test, and McNemar's test. Results : The study showed that participants were very satisfied with and had significant health improvements after the wellness tourism program. The program was also found to be beneficial in improving participants' emotions as follows: BDI (p<.001), fatigue recovery (p=.006), stress relief (p=.003), improved quality of life (p<.05), and improved sleep quality (p<.001). Conclusion : Wellness tourism programs are specifically beneficial for improving participants' emotions (depression, anxiety), fatigue, stress levels, quality of life, and sleep. Therefore, they are beneficial to the overall health. Further research in the future by way of a follow-up study on the long-term effects on health after short-term interventions will provide more validation data.

• Mycobiology
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• 제43권4호
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• pp.435-443
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• 2015

Sixty-one endophytic fungus strains with different colony morphologies were isolated from the leaves, stems and roots of Tephrosia purpurea with colonization rates of 66.95%, 37.50%, and 26.92%, respectively. Based on internal transcribed spacer sequence analysis, 61 isolates were classified into 16 genera belonging to 3 classes under the phylum Ascomycota. Of the 61 isolates, 6 (9.84%) exhibited antifungal activity against one or more indicator plant pathogenic fungi according to the dual culture test. Isolate TPL25 had the broadest antifungal spectrum of activity, and isolate TPL35 was active against 5 plant pathogenic fungi. Furthermore, culture filtrates of TPL25 and TPL35 exhibited greater than 80% growth inhibition against Sclerotinia sclerotiorum. We conclude that the endophytic fungal strains TPL25 and TPL35 are promising sources of bioactive compounds.

• 한국식품영양학회지
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• 제34권5호
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• pp.477-486
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• 2021

To utilize Malus pruniforia Borkh. as a functional material, cold-water (CW), hot-water (HW), and 70% ethanol (EtOH) extracts were prepared, and their antioxidant and anti-inflammatory activities were compared. The antioxidant activity of the HW extract evaluated by ABTS and DPPH radical scavenging and FRAP activity was significantly effective. The total polyphenol content of the HW extract was also higher by 15.5±0.7 mg GAE/g extract compared to other extracts. The EtOH extract showed significantly decreased TNF-α (39.8%), IL-6 (65.5%), and NO (34.9%) levels in RAW 264.7 cells compared to the LPS-induced control group. The levels of IL-6 (21.1%) and IL-8 (19.3%) were significantly decreased by treatment of EtOH extract in HaCaT keratinocytes induced with TNF-α and IFN-γ. The UHPLC-MS results indicated that the EtOH extract might have chlorogenic acid and phlorizin as the major compounds. This was validated using HPLC-DAD, which showed that the EtOH extract had higher levels of chlorogenic acid and phlorizin (1,185±58 and 470±10 ㎍/g extract, respectively). In conclusion, the present study suggested that the anti-inflammatory activity of the EtOH extract was more effective than the CW and HW extracts, and chlorogenic acid and phlorizin could be used as indicator compounds and functional substances.