• Title/Summary/Keyword: Functional Prototype

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Molecular divergence of the fish somatomedins: the single family of insulin­like growth factor (IGF)-I and -II from the teleost, flounder

  • Kim Dong Soo;Kim Young Tae
    • Fisheries and Aquatic Sciences
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    • v.1 no.2
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    • pp.227-231
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    • 1998
  • The teleosts represent ancient real-bony vertebrates in phylogeny and resemble major genetic patterns to higher vertebrates. In the present study, we have defined the single family of insulin-like growth factors (IGFs) from flounder (Paralichthys olivaceus), compared to the prototype of IGFs observed in the Agnathan hagfish. In flounder, IGFs are clearly diverged into two major types including type I and II, and they are structurally similar by displaying a multidomain structure consisting of five functional regions as previously found in other vertebrates. However, flIGF-I appears to be more basic (pI 8.03) than the flIGF-II (pI 5.34) in the fully processed form for the B to D domain region. The flIGF-I seems to contain an evolutionary conserved Asn-linked glycosylation in E domain, which is not found in flIGF­II. The most interesting feature is that flIGF-II appeared to be structurally close to hagfish IGF in secondary structures, particularly in Band D domains. This could tell us an idea on the molecular divergence of IGFs from the Agnatha to teleosts during the vertebrate phylogeny. It also support, in part, a notion regarding on how IGF-II is appeared as more embryonic during development. Nonetheless, the biologically active B to D domain region of flIGF-II shows significant sequence homology of $65.6\%$ to flIGF-Is and contains the evolutionary conserved insulin-family signature, as well as a reserved recognition site (Lys) in D domain, necessary to generate proteolytic cleavage for E-peptide. A significant structural difference was found in E domain in which flIGF-I possesses two potential alternative splicing donor site at $Val^{17,\;24}$ of E domain. Therefore, it seems so far that IGF-I sorely produces spliced variants due to the spliced E-peptide moiety while IGF-II appears to be maintained in a single type during evolution. IGF-II, however, may be also possible to transcribe unidentified variants, depending on the physiological conditions of tissues in vertebrates in vivo.

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A Functional Review and Prototype for Ship PDM implementation (조선 PDM구축을 위한 기능 연구 및 시험 구현 사례)

  • Lee, Jang-Hyun;Kim, Yong-Gyun;Oh, Dae-Kyun;Shin, Jong-Gye
    • Journal of the Society of Naval Architects of Korea
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    • v.42 no.6 s.144
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    • pp.686-697
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    • 2005
  • The current challenge with which most shipyards are faced is to reduce the design time and the time-to-delivery benefits of new information technologies such as ERP, APS, and SCM system. These technologies should integrate the information that flows in the enterprise wide activities. First of all we should maintain control of ship design and product data such as bill of material, product structure, drawing, 30 modeling and manufacturing information for the integration. The product data management (POM) system copes with these requirements. All the product data is stored in POM database and vaults in a structured manner and all the changes of product data are monitored, controlled and recorded. This study discusses how POM system can be implemented in shipyard. The procedure is surveyed to apply a POM system for the ship design data management. This study also presents several examples in order to make a practical guidance for ship POM implementation. Proposed studies can be useful for shipyards planning to adopt POM systems in enterprise wide manner.

A Development of Multi-Emotional Signal Receiving Modules for Ubiquitous RCP Interaction (유비쿼터스 RCP 상호작용을 위한 다감각 착신기능모듈의 개발)

  • Jang Kyung-Jun;Jung Yong-Rae;Kim Dong-Wook;Kim Seung-Woo
    • Journal of Institute of Control, Robotics and Systems
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    • v.12 no.1
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    • pp.33-40
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    • 2006
  • We present a new technological concept named RCP (Robotic Cellular Phone), which combines RT and CP. That is an ubiquitous robot. RCP consists of 3 sub-modules, RCP Mobility, RCP interaction, and RCP Integration. RCP Interaction is the main focus of this paper. It is an interactive emotion system which provides CP with multi-emotional signal receiving functionalities. RCP Interaction is linked with communication functions of CP in order to interface between CP and user through a variety of emotional models. It is divided into a tactile, an olfactory and a visual mode. The tactile signal receiving module is designed by patterns and beat frequencies which are made by mechanical-vibration conversion of the musical melody, rhythm and harmony. The olfactory signal receiving module is designed by switching control of perfume-injection nozzles which are able to give the signal receiving to the CP-called user through a special kind of smell according to the CP-calling user. The visual signal receiving module is made by motion control of DC-motored wheel-based system which can inform the CP-called user of the signal receiving through a desired motion according to the CP-calling user. In this paper, a prototype system is developed far multi-emotional signal receiving modes of CP. We describe an overall structure of the system and provide experimental results of the functional modules.

A Study of One-to-One Custom Application for Breast Cancer Patient -Focusing on Service Design Methods- (유방암 환자를 위한 1:1 맞춤형 애플리케이션 연구 -서비스 디자인 방법을 중심으로-)

  • Chae, Min-Young;Kim, Seung-In
    • Journal of Digital Convergence
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    • v.15 no.7
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    • pp.367-373
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    • 2017
  • The study aims to suggests mobile application service that helps to reduce physical and mental suffering after surgery for breast cancer patients constantly increasing. At first, I analyze literature research to understand the breast cancer and similar services for achieving study purposes. After I finally design a mobile application that offers to customed one-to-one specialist coaching service focused on post-treatment management by using a double diamond design process model. In detail, first, I analyze the current program and comprehend user needs through interviews with the person such as breast patient, protector, nurse, salesperson in cancer center. Second, I specify the entire scenario, concept and keyword based on the persona and the customer journey map representing user. Third, I propose the mobile application for the ultimate goal by producing prototype to effectively communicate with specific functional descriptions. I hope this service will improve the quality of their lives.

Data Collection Methods to Standardize Protocols of Safety Supervision System (안전관제시스템 프로토콜 표준화를 위한 데이터 수집 방법)

  • Shin, Kwang-Ho;Um, Tae-Hwa;Lim, Dam-Sub;Ahn, Jin
    • Journal of the Korean Society for Railway
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    • v.19 no.2
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    • pp.159-169
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    • 2016
  • The current railway control system in Korea is comprised of signaling, electric rail power, communication, and maintenance systems that are independent of each other. Further, these systems have different mediums and protocols for transmitting the field equipment data to the central control system. The Safety Supervision System has as its purpose the collecting of safety-related data from each system to predict and prevent accidents, this system utilizes standard protocol. Safety-related data need to be collected from field data transmission devices of the existing control system, the data should be collected without affecting the communication of the existing system. In this study, sniffing skill, which is typically used for network traffic monitoring or security, is used to collect data. The problems arising from the use of sniffing devices are noted, and the Packet Conversion Node is proposed as a solution to the problems. Further, functional and performance testing were completed for the prototype, and the software architecture and packet conversion process were verified.

International Standardization and Implementation of Home Energy Saving System for Smart Grid (스마트 그리드를 위한 홈 에너지 절감 시스템의 IEC 국제표준화 및 구현)

  • Choi, Kwang-Soon;Lee, Sang-Won;Park, Young-Choong;Jung, Kwang-Mo
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.37C no.12
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    • pp.1222-1229
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    • 2012
  • For the reduction of electric energy consumption and its efficient use at homes or buildings, a new work item proposal for new architecture and functional requirements of Energy Saving System (ESS) was proposed to IEC TC 100 and accepted as a new project, IEC PT 62654 in 2009. Recently, the final ballot for publication passed without negative votes and IEC TS 62654 was finally published in August 2012. For the verification of this standard, Prototype of ESS system composed of an ESS server, ESS clients, and portable ESS terminal were especially implemented in parallel with the standardization. Electric Power Control and Management (EPCM) protocol for the communication between ESS server and clients was also implemented, which supports self-configuration of ESS network, power consumption monitoring, remote power control, and additional functions for intelligent energy saving services.

Development of Automatic Reference-Citation-Mark Attachment Support System (참고문헌 인용부호 자동부착 지원 시스템 개발)

  • Song, Kwangho;Min, Jihong;Kim, Yoo-sung
    • KIISE Transactions on Computing Practices
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    • v.21 no.10
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    • pp.623-630
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    • 2015
  • In this paper, the design and implementation of an automatic reference-citation-mark attachment system are introduced. The system automatically attaches a citation mark to the end of a sentence in a technical document if the corresponding statement has a high similarity to another statement in the same document; simultaneously, the corresponding bibliographic data is automatically created from the cited-document information. In accordance with functional specifications, a Web-based, online service model and the development of its prototype system are proposed. The developed system can help in the elimination of unexpected plagiarism issues, and will alleviate the burdens of reference citation and reference-list creation for technical writers.

Functional Implication of the tRNA Genes Encoded in the Chlorella Virus PBCV-l Genome

  • Lee, Da-Young;Graves, Michael V.;Van Etten, James L.;Choi, Tae-Jin
    • The Plant Pathology Journal
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    • v.21 no.4
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    • pp.334-342
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    • 2005
  • The prototype Chlorella virus PBCV-l encodes 11 tRNA genes and over 350 protein-encoding genes in its 330 kbp genome. Initial attempts to overexpress the recombinant A189/192R protein, a putative virus attachment protein, in E. coli strain BL21(DE3) SI were unsuccessful, and multiple protein bands were detected on Western blots. However, the full-length A189/192R recombinant protein or fragments derived from it were detected when they were expressed in E. coli BL21 CodonPlus (DE3) RIL, which contains extra tRNAs. Codon usage analysis of the a189/192r gene showed highly biased usage of the AGA and AVA codons compared to genes encoded by E. coli and Chlorella. In addition, there were biases of XXA/U($56\%$) and XXG/ C($44\%$) in the codons recognized by the viral tRNAs, which correspond to the codon usage bias in the PBCV-1 genome of XXA/U ($63\%$) over those ending in XXC/G ($37\%$). Analysis of the codon usage in the major capsid protein and DNA polymerase showed preferential usage of codons that can be recognized by the viral tRNAs. The Asn (AAC) and Lys (AAG) codons whose corresponding tRNA genes are duplicated in the tRNA gene cluster were the most abundant (i.e., preferred) codons in these two proteins. The tRNA genes encoded in the PBCV-l genome seem to play a very important role during the synthesis of viral proteins through supplementing the tRNAs that are frequently used in viral proteins, but are rare in the host cells. In addition, these tRNAs would help the virus to adapt to a wide range of hosts by providing tRNAs that are rare in the host cells.

A Study on Adaptive Operation Control to Stabilize bus Voltage of GEO Satellite Power Supply Module (정지궤도 위성용 전력공급 모듈의 버스 전압 안정화를 위한 최적동작 제어에 관한 연구)

  • Ahn, Tae-Young;Choe, Hyun-Su
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.2
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    • pp.123-129
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    • 2016
  • In this paper, results of produced PCU(Power Control Unit) prototype was showed by suggesting and maintaining optimal operation status which let the three functional modules automatically operate with its necessity by prioritizing operation process. In order to validate effectiveness of the suggested method, we produced a test PCU and examined the results. PCU consists of S3R(Sequential Switching Shunt Regulator), BCR(Battery Charge Regulator), and BDR(Battery Discharge Regulator): converting photovoltaic power into constant voltage at linked bus voltage; storing dump power in the battery which is an auxiliary energy storage device; and supplying power charged in battery to the load. To maintain its high reliability and optimal condition of these three power conversion modules, each module operates in parallel and stable bus voltage is required to be retained at all-time due to the nature of power supply for satellite.

Consumer Perception and Evaluation of Cynanchi Atrati Radix Fermented Oriental Cosmetics for Skin Whitening (피부 미백용 백미발효 한방 화장품에 대한 소비자 인식과 평가)

  • Son, Chang-gue;Jang, Eun-su;Lee, Sam-keun;Barng, Kee-jung
    • Journal of Fashion Business
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    • v.23 no.5
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    • pp.137-150
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    • 2019
  • This study aimed to provide consumer perception and evaluation of natural Cynanchi Atrium Fermented Original Cosmetics for Skin Whitening that can improve skin by using oriental medicinal ingredients. The product was applied three times a day for two weeks by a total of 60 users who agreed to participate in a clinical trial assessing the usability and skin sensitivity to extracts that had already completed component safety testing. This study subjects reported which images were most reminiscent of Korea. They preferred products that bore Korean images because they felt trust and recognized that the quality of the cosmetics was excellent. The responses also showed that many consumers were willing to buy a product, even though it was luxurious, elegant, and expensive. The cognitive evaluation of Original Cosmetics was high and showed that the quality was likely to be good. The usability and CMF(Color, Material, Finishing) evaluation of Original Cosmetics showed good product the product is long-lasting and tightened and moisturized skin naturally. They are think about that this product it has moisturizing effects and good application for use, so it is light and soft to use. And had a whitening effect. It was intended to assist in the development of products that meet consumers' desires and expectations for safe, healthy, and beautiful skin by developing a skin whitening Original Cosmetics prototype that can inhibit the production of melanin and tyrosinase activity safely and effectively.