• ETRI Journal
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• 제40권5호
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• pp.653-663
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• 2018

Patients with spinal cord injuries cannot move their limbs using their intact muscles. A suitable controller can be used to move their arms by employing the functional electrical stimulation method. In this article, a fuzzy exponential sliding-mode controller is designed to move a musculoskeletal human arm model to track an optimal trajectory in the sagittal plane. This optimal arm trajectory is obtained by developing a policy for the central nervous system. In order to specify the optimal trajectory between two points, two dynamic and static optimal criteria are applied simultaneously. The first dynamic objective function is defined to minimize the joint torques, and the second static optimization is offered to minimize the muscle forces at each moment. In addition, fuzzy logic is used to tune the sliding-surface parameter to enable an appropriate tracking performance. Simulation results are evaluated and compared with experimental data for upward and downward movements of the human arm.

• 대한의용생체공학회:의공학회지
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• 제17권4호
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• pp.459-468
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• 1996

This paper considers the problem of realising a parallel EMG identifier used in FES (functional electrical stimulation) system on a fixed dimension transputer array. This involves using an identifiestion algorithm in the wavelet transform domain. This algorithm have suggested by the authors in a previous paper(6). The transputer serial links permit higtlly varied and economic network-type connections and the structure enables rapid topological reconfiguration. Analysing the results Showed that the Speed-UPS ranged from 1.82 to 3.44 With 2-4 transputers for corresponding model order, and from 1.82 to 3.97 with increasing the model orders when two and four transputers are used respectively.

• 대한의용생체공학회:의공학회지
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• 제25권6호
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• pp.479-487
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• 2004

중추신경계손상으로 인하여 약화된 근육기능을 회복하기 위한 전기자극의 제어신호로 생체신호를 이용하고 있다. 생체신호중에서 마비된 근육에서 발생되는 자발적이면서 근수축을 하기에 부족한 자발근전도신호로 전기자극의 강도를 조절해야 하는 경우, 전기자극에 의해 발생되어 자발근전도신호에 섞이는 M-wave를 제거해야 한다. 본 연구에서는 M-wave를 제거하고 동시에 자발근전도신호의 크기를 보존하기 위한 최적필터를 설계하였고 최적필터의 계수는 입력 공분산 행렬의 최소고유치에 해당하는 고유벡터가 됨을 보였으며. inverse Power methd(IPM)을 사용하여 이를 적응적으로 구현하는 과정을 통해 기존의 예측오차필터 방법이 부최적 방법임을 보였다. 최적필터의 성능을 평가하기 위하여 모의데이터에 대한 false-positive rate를 측정하여 분석하였으며, 실험결과는 최적필터가 이전에 연구되었던 예측오차필터에 비해 효과적으로 M-wave를 제거할 수 있음을 보여준다.

• Journal of Acupuncture Research
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• 제23권3호
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• pp.155-163
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• 2006

Objectives : This study was designed to evaluated the effect of electro acupuncture on Heart Rate Variability of Patients with functional voiding disease. Methods: Subjects were voluntarily recruited by newspapers and internet. Electro acupuncture was performed three times a week for 3 weeks. Acupuncture point for EA group was B32, Electrical stimulation frequency was 2Hz, duration 20min, and intensity was up to pain threshold according to patients. The patients' Heart Rate Variability was measured before, after 3 weeks of treatment for 5 minutes. Results : In time domain analysis, There were significant increase of SDNN and RMSSD(p<0.05) after 3 weeks treatment. In frequency domain analysis, There were significant increase of LF and LF /HF ratio(p<0.05) after 3 weeks treatment. There were no significant changes in other components of heart rate variability. Conclusion : This study suggests that electroacupuncture treatments can be applicable to improve autonomic nervous system in patients with functional voiding disease.

• Annals of Clinical Neurophysiology
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• 제1권1호
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• pp.10-18
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• 1999

연구배경 및 목적 : 시각 인지 과정은 영장류 실험을 통하여 다소 정보를 얻을 수 있었으나 인간에서는 아직 완전하게 이해되지 않고 있다. 이 연구의 목적은 뇌자극과 시가유발전위 검사를 토대로 인간의 시각피질의 기능적 분화와 시간 순으로 활성화되는 양상을 보고자 한 것이다. 연구방법 : 간질 수술을 위하여 후두엽과 인접 부위에 광범위하게 피질하전극을 넣은 22명의 환자를 대상으로 전기적 뇌자극과 시각유발전위 검사를 시행하였다. 뇌자극시 나타나는 반응은 형태, 색, 및 움직임의 세 가지로 크게 나누고 형태는 다시 단순, 중간 및 복잡한 형태로 세분하였다. 시각유발전위는 P1 혹은 IV파의 latency를 측정하였다. 결과 : 단순 혹은 중간 형태는 흔히 occipital pole과 striate cortex에서 발생하였다. 색반응은 후두엽의 기저부 즉, fusiform, lingual, inferior occipital gyri를 자극할 때 관찰되었다. 움직임 반응은 내측기저부 및 외측의 측후두엽 혹은 측두정후두부의 경계부에서 주로 나타났다. 결론 : 이러한 결과는 인간의 시각피질이 시각의 여러 가지 구성성분 즉, 형태, 색, 및 움직임에 대해서 각각 별도로 분화되어 있다는 것을 보여준다. 도한 시각자극이 전해지면 striate cortex와 occipital pole이 가장 먼저 활성화되고 이어서 내측 및 외측 후두엽 부위가 활성화된다는 것을 알 수 있다. 이러한 사실을 종합하여 보면 인간의 시각피질은 시각의 여러 구성성분별로 별도로 발달된 해부학적 경로를 통하여 각각의 기능에 대하여 특수하게 분화된 뇌세포에서 시각정보를 각각 분석하되 일정한 시간순서에 의한다는 것을 시사하는 것이다.

• Annals of Clinical Neurophysiology
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• 제8권1호
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• pp.29-35
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• 2006

Background: Transcranial magnetic stimulation (TMS) is a non-invasive diagnostic method particularly suited to investigation the long motor tracts. The clinical value of TMS in most spinal cord diseases has still to be made. Diagnostic value of magnetic motor evoked potential (MEP) parameters in intramedullary spinal cord lesions was investigated. Methods: MEP elicited by TMS was recorded in 57 patients with clinically and radiologically defined intramedullary myelopathy. Twenty five patients with cervical myelopathy (CM) and 32 thoracic myelopathy (TM) were included. Recordings were performed during resting and minimal voluntary contraction at both abductor pollicis brevis (APB) and tibialis anterior (TA) muscles. Stimulation threshold(ST), amplitude, and central motor conduction time (CCT) were measured at resting and facilitated conditions. CCT was calculated by two means; central motor latency (CML)-M using magnetic transcranial and root stimulation, and CML-F using electrical F-wave study. The results were compared between patient groups and 10 normal control group. Results: Facilitated mean ST recorded at TA was elevated in both CM and TM compared with control group. Resting mean CML-M at TA was significantly prolonged in both CM and TM, and CML-M was absent or delayed in 37.1% of CM and 8% of TM at APB with facilitation. Facilitated mean MEP amplitude at ABP was lower in CM than in TM, while MEP/M ratios were not different significantly between groups. Conclusions: Magnetic motor evoked potential has diagnostic value in intramedullary myelopathy and localizing value in differentiating between CM and TM by recording at APB and TA. It is a noninvasive way to investigate the functional status of motor tracts of spinal cord.

• 대한의용생체공학회:의공학회지
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• 제28권2호
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• pp.212-217
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• 2007

As a preliminary study for the development of electrical stimulation strategy of artificial retina, we set up a method fur the reconstruction of input intensity variation from retinal ganglion cell(RGC) responses. In order to estimate light intensity variation, we used an optimal linear filter trained from given stimulus intensity variation and multiple single unit spike trains from RGCs. By applying ON/OFF stimulation(ON duration: 2 sec, OFF duration: 5 sec) repetitively, we identified three functional types of ganglion cells according to when they respond to the ON/OFF stimulus actively: ON cell, OFF cell, and ON-OFF cell. Experiments were also performed using a Gaussian random stimulus and a binary random stimulus. The input intensity was updated once every 90 msec(i. e. 11 Hz) to present the stimulus. The result of reconstructing 11 Hz Gaussian and binary random stimulus was not satisfactory and showed low correlation between the original and reconstructed stimulus. In the case of ON/OFF stimulus in which temporal variation is slow, successful reconstruction was achieved and the correlation coefficient was as high as 0.8.

• The Journal of Korean Physical Therapy
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• 제18권1호
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• pp.65-73
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• 2006

Purpose: The purpose of this study was to identify the effect of electroacupuncture(EA) and transcutaneous electric nerve stimulation(TENS) after sciatic nerve crush injury in rats. Methods: The EA for experimental group I (Exp I, n=15) and TENS for experimental group II (Exp II, n=15) was applied from post-injury day(PD) 1 to PD 14 after sciatic nerve injury using low frequency stimulator that gave electrical stimulation(15min/60Hz). In order observe the effect of EA and TENS, this study examined GAP-43 expression in rat lumbar spinal cord at the PD 1, PD 7 and PD 14. In addition, the stride length(SL) and toe out angle(TOA) were measured at the PD 7 and PD 4. Results; Exp I and Exp II had higher GAP-43 immunoreactivity than control group(PD 1, 7, 14). The SL of Exp I and Exp II were significantly higher than control group(PD 7, 14). The TOA of Exp I and Exp II were significantly lower than control group(PD 7, 14). Conclusion: EA and TENS application increased motor nerve recovery and expression of GAP-43 immunoreactivity after sciatic nerve crush injury. Therefore effect of TENS and EA had similar effect on nerve regeneration and functional recovery.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1991년도 춘계학술대회
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• pp.34-38
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• 1991

This paper describes and discusses the employment of EMG pattern analysis to provide upper-motor-neuron paraplegics with patient-responsive control of FES (functional electrical stimulation) for the purpose of walker-supported walking. The use of above - lesion EMG signals as a solution to the control problem is considered. The AR (autoregressive) parameters are identified by Kalman filter algorithm using DSP chip and classified by fuzzy theory. The control and stimuli part of the below-lesion are based on microprocessor(8031). The designed stimulator is a 4-channel version. The experiments described above have only attempted to discriminate between standing function and sit-down function. A further advantage of the this system is applied for motor rehabilitation of social readaption of paralyzed humans.

• 한국정밀공학회지
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• 제21권8호
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• pp.171-179
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• 2004

The purpose of this study is to generate cycling motion for FES (functional electrical stimulation) using knee muscles only. We investigated the possibility by simulation. The musculoskeletal model used in this simulation was simplified as 5-rigid links and 2 muscles (knee extensor and flexor). For the improvement of the present feedforward control in FES, we included feedback path in the control system. The control system was developed based on the biological neuronal system and was represented by three sub-systems. The first is a higher neuronal system that generates the motion command for each joint. The second is the lower neuronal system that divides the motion command to each muscle. And the third is a sensory feedback system corresponding to the somatic sensory system. Control system parameters were adjusted by a genetic algorithm (GA) based on the natural selection theory. GA searched the better parameters in terms of the cost function where the energy consumption, muscle force smoothness, and the cycling speed of each parameter set (individual) are evaluated. As a result, cycling was implemented using knee muscles only. The proposed control system based on the nervous system model worked well even with disturbances.