• Investigative Magnetic Resonance Imaging
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• v.16 no.1
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• pp.55-66
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• 2012

Purpose : During brain MRI scanning, subject's head motion can adversely affect MRI images. To minimize MR image distortion by head movement, we developed an optical tracking system to detect the 3-D movement of subjects. Materials and Methods: The system consisted of 2 CCD cameras, two infrared illuminators, reflective sphere-type markers, and frame grabber with desktop PC. Using calibration which is the procedure to calculate intrinsic/extrinsic parameters of each camera and triangulation, the system was desiged to detect 3-D coordinates of subject's head movement. We evaluated the accuracy of 3-D position of reflective markers on both test board and the real MRI scans. Results: The stereo system computed the 3-D position of markers accurately for the test board and for the subject with glasses with attached optical reflective marker, required to make regular head motion during MRI scanning. This head motion tracking didn't affect the resulting MR images even in the environment varying magnetic gradient and several RF pulses. Conclusion: This system has an advantage to detect subject's head motion in real-time. Using the developed system, MRI operator is able to determine whether he/she should stop or intervene in MRI acquisition to prevent more image distortions.

• Korean Journal of Applied Biomechanics
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• v.21 no.4
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• pp.487-494
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• 2011

The purpose of this study was to evaluate the effects of metatarsal pad (MP) compared with barefoot and MP with using different insoles on gait. 15 healthy females who had no history of injury in the lower extremity with an average age of 22.7 year(SD=1.35), height of 160 cm(SD=3.4), weight of 48.8 kg(SD=5.52) and average foot size of 232.5 mm(SD=6.8) participated in this study as the subjects. The subjects walked on a treadmill under four different experimental conditions: 1) walking with barefoot, 2) walking wearing MP 3) walking wearing a soft insole with MP(SIMP), 4) walking wearing a rigid insole with MP(HIMP). During walking, foot pressure data such as force, contacting area, peak pressure, and mean pressure was collected using Pedar-X System(Novel Gmbh, Germany) and EMG activity of lower limb muscles such as tibialis anterior(TA), lateral gastrocnemius(LG), rectus femoris(RF), and musculus biceps femoris(MBF) was gathered using Delsys EMG Work System(Delsys, USA). Collected data was then analyzed using paired t-test in order to investigate the effects of each of experimental conditions. As a result of the analysis, when MP and HIMP were equipped, overall contacting area was increased while the force, peak pressure and the mean pressure were decreased. Especially, when the SIMP was equipped, every data were significantly decreased. In case of EMG, wearing MP, SIMP and HIMP made three muscles(TA, LG, RF)'s activity decrease. A result of the analysis will be able to apply for manufacturing functional shoes, diabetes shoes, senior shoes and lower extremity orthosis. Significance of the study due to a metatarsal pad and the insole is to analyze the changes in muscle strength.

• Physical Therapy Korea
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• v.5 no.4
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• pp.1-8
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• 1998

본 연구의 목적은 장애물 높이에 따른 상지 팔운동 제한이 스텝안정화(stabilization step)에 영향을 주는지 알아보기 위하여 실시하였다. 연구대상자는 대학생 남자 14명, 여자 16명으로 총 30명이였으며, 평균 연령은 21.5세이었다. 스텝 안정화는 FASTEX(functional activity System for testing and exercise, Cybex Division of Lumex, Inc., USA)를 이용하여 측정하였다. 장애물의 조건은 1) 장애물이 없는 조건 2) 15 cm 장애물 3) 25 cm 장애물이었고, 팔 운동의 제한 조건은 1) 팔운동을 제한하지 않은 조건 2) 우세 팔의 운동 제한 3) 양쪽 팔을 모두 제한하는 3개의 조건에서 스텝 안정화 시간을 측정하였다. 장애물 요인과 팔운동 제한 요인간에 안정화 시간(stabilization time)의 차이가 있는지 알아보기 위하여 반복이 있는 2요인 분산분석을 실시하였고, 남녀간에 안정화 시간에 차이가 있는지 알아보기 위하여 t-검정을 실시하였다. 장애물이 없는 조건에서 양팔의 운동을 제한하지 않고 측정한 안정화 시간의 평균은 0.89초이었고, 건측의 상지운동을 제한한 상태에서의 평균은 0.88초이었으며, 양쪽 팔의 운동을 모두 제한했을 때의 평균은 0.84초이었다. 15 cm의 장애물이 있는 조건에서 양팔의 운동을 제한하지 않고 측정한 안정화 시간은 평균 0.98초이었고, 건측의 상지운동을 제한한 상태에서의 펑균은 1.00초이었으며, 양쪽 팔의 운동을 모두 제한했을 때의 평균은 1.14초이었다. 25 cm의 장애물이 있는 조건에서 양팔의 운동을 제한하지 않고 측정한 안정화 시간은 평균 1.09초이었고, 건측의 상지운동을 제한한 상태에서의 평균은 1.28초이었으며, 양쪽 팔의 운동을 모두 제한했을 때의 평균은 1.57초이었다. 남녀간의 스텝 안정화 시간에 차이가 있는지 알아본 결과 각각의 조건에서 통계학적으로 유의한 차이가 없었다. 장애물과 팔운동 제한 조건에 따른 스텝 안정화 시간의 차이가 있는지 알아보기 위하여 반복이 있는 2요인 분산분석을 실시한 결과, 장애물의 높이에 따라 스텝 안정화 시간에는 유의한 차이가 있었고(p<0.05), 15 cm, 25 cm 장애물 조건에서는 팔운동 제한 조건에 따른 스텝 안정화 시간에도 유의한 차이가 있었지만(p<0.05), 장애물이 없는 조건에서는 팔운동 제한에 따른 안정화 시간에는 유의한 차이가 없었다. 이상의 결과는 보행중 장애물을 넘고, 한발로 기립하여 안정성을 유지할 때 팔의 운동이 스텝 안정성에 영향을 미친다는 것을 알았고, 이러한 결과는 한팔 또는 두 팔을 사용할 수 없는 편마비환자나 상지 절단환자의 균형 평가나 치료시 고려되어져야 할 것이다.

• Nutrition Research and Practice
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• v.5 no.4
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• pp.288-293
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• 2011

In this study, we investigated the effects of the ethanol extract of aerial parts of Raphanus sativus L. (ERL) on breast cancer cell proliferation and gene expression associated with cell proliferation and apoptosis in MDA-MB-231 human breast cancer cells. The MDA-MB-231 cells were cultured in the presence or absence of various concentrations (100, 200, or 300 ${\mu}g$/mL) of ERL. ERL significantly decreased cell proliferation after 48 h of incubation (P < 0.05). The protein and mRNA expression of $ErbB_2$ were decreased significantly in a dose-dependent manner (P < 0.05). The protein expression of $ErbB_3$ was decreased significantly at an ERL concentration of 300 ${\mu}g$/mL (P < 0.05), and mRNA expression of $ErbB_3$ was decreased significantly in a dose-dependent manner (P < 0.05). The protein expression of Akt was decreased significantly at the ERL concentration of 200 ${\mu}g$/mL (P < 0.05), and the protein expression of pAkt was decreased significantly in a dose-dependent manner (P < 0.05). The mRNA expression of Akt was decreased significantly at the ERL concentration of 200 ${\mu}g$/mL ERL (P < 0.05). The protein and mRNA expression of Bax were increased significantly at ERL concentrations of 200 ${\mu}g$/mL or higher (P < 0.05). The protein expression of $Bcl_2$ was increased significantly at ERL concentrations of 100 ${\mu}g$/mL or higher (P < 0.05), and mRNA expression of $Bcl_2$ was increased significantly at an ERL concentration of 300 ${\mu}g$/mL (P < 0.05). In conclusion, we suggest that Raphanus sativus, L. inhibits cell proliferation via the ErbB-Akt pathway in MDA-MB-231 cells.

• Journal of the East Asian Society of Dietary Life
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• v.23 no.6
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• pp.818-826
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• 2013

To reduce the production cost of Lactobacillus, discarded red ginseng starch was collected from a factory of red ginseng extract in order to develop the Lactobacillus culture medium. According to the analysis of the gensenoside composition of red ginseng starch, the total gensenoside content of starch was 2.73 mg/g, and the gensenoside $Rb_1$, $Rb_2$ and $Rg_3$ contents were 0.1, 0.29 and 0.52 mg/g, respectively. For the preparation of the liquid media, red ginseng starch was added at rates of 0, 5, 10 and 20%. Further, Lactobacillus plantarum 15357 and Leuconostoc mesenteroides sub sp. strains were then inoculated to these prepared broths. With the red ginseng starch medium, the growth rates ($1.42{\times}10^7$ and $2.96{\times}10^{10}$ CFU/mL) and the final cell concentrations were higher than the MM medium ($1.0{\times}10^7$ CFU/mL). The optimal concentration of red ginseng starch and yeast extract as a medium were 20% and 10 g/L, respectively. Under these conditions, the cell mass of L. plantarum 15357 and L. mesenteroides sub sp. reached $5.11{\times}10^{10}$ and $8.17{\times}10^{10}$ CFU/mL. These results show a great possibility for the utilization of red ginseng starch as economic medium sources in the production of cell mass of lactic acid bacteria. This is the first trial of development of economic LAB growth medium using discarded red ginseng starch.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.38 no.3
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• pp.255-261
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• 2012

The skin is continuously exposed to environmental stresses. One of the most important stress factor is UV radiation. UV radiation causes a variety of biological effects on the skin, including inflammation, pigmentation, photoaging and cancer. Therefore in this study, we tried to search for skin-protective antioxidant materials from marine natural products (Porphyra Thalli, Laminariae japonicae thallus, Ostreae Concha, Sargassum Thallus, Undaria thallus, Haliotidis Concha, Agar, Codium thalli, Hizikia fusiforme thalli; HFE, Thalli) which exhibit protective activities against UVB-induced cytotoxicity and oxidative cell death and antiaging effects. As a results, UVB-induced cytotoxicity and cell death were effectively suppressed by treatment of Sargassum Thallus, Agar, Haliotidis Concha, Codium thalli, Thalli ethanol extracts. UVB-induced cell death was mediated by intracellular accumulation or ROS, which was significantly inhibited by treatment with marine natural products extracts. Also, The protective effect of these marine natural products seemed to be mediated by increased expression of type I collagen and Type I procollagen. These results suggest that marine natural products may have anti-aging effects new functional materials against oxidative stress-mediated skin damages.

• Korean journal of applied entomology
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• v.48 no.3
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• pp.347-354
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• 2009

This study was conducted on the biological control effects of the natural enemy, Amblyseius cucumeris, against Polyphagotarsonemus latus. The broad mite moved to a new habitat after the carrying capacity of the preferred habitat on the upper leaf has been reached. Population dynamics between predator, Amblyseius cucumeris, and prey, P. latus, were quite well synchronized since the predator followed the movement of the prey. In predation test by Amblyseius cucumeris on P. latus, A. cucumeris fed on 8.8, 15.2, 27.0 and 30.3 individuals/day under the temperatures of 15, 20, 25, and $30^{\circ}C$, respectively. The A. cucumeris larva, protonymph, deutonymph, adult male, and adult female fed on 0.5, 1.6, 5.2, 3.8, and 27 individuals of adult P. latus per day, respectively, under $25^{\circ}C$ condition. The functional response curve of adult P. latus to the densities of A. cucumeris showed Holling's Type II curve. The consumption of prey by A. cucumeris increased with the prey density increase, but the consumption rate decreased. The critical ratio of predator vs. prey effectively to suppress (98% over) the population of P. latus by releasing A. cucumeris was 1:40 on red pepper.

• Korean Journal of Ichthyology
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• v.21 no.4
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• pp.262-272
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• 2009

Upstream behavior of glass eels was examined in an experimental eel-ladder at a laboratory of the National Fisheries Research and Development Institute from March to May in 2008. The study was made under various environmental factors and conditions affecting the upstream migration of glass eels in order to design a functional ladder that would allow the passage of glass eels. The experimental eel-ladder consisted of an upper freshwater chamber and a lower sea water chamber; glass eels in sea water can move up to the upper freshwater chamber through the slope (eel-ladder) between them. The optimal condition of the eel-ladder was estimated by comparing the number of glass eels that moved upstream depending on various conditions. Since the glass eels actively moved up the slope to river water rather than to reservoir water or tap water, the experiment was realized using river water. A significantly higher number of glass eels moved up during the spring tide than during the neap tide, and during night than during the day. Upstream movement was significantly higher during high tide than during low tide. Glass eels effectively moved up through a slope of less than $30^{\circ}$ and water-flow velocity lower than 0.4 m/sec. The fish preferred a coarser ladder bed covered with small gravels, brush or carpet.

• Journal of Life Science
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• v.23 no.6
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• pp.751-756
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• 2013

This research old age chestnut tree that loss function chestnut leaf renewal efficiency enlargement and development of cosmeceutical product by purpose. Chestnut leaf (CL) exhibits numerous pharmacological effect including anti-allergy and anti-microbial properties. However, the anti-wrinkle effect of CL is not completely understood. In this study, to find a possible explanation for the anti-wrinkle effects of CL, we evaluated the effects of CL on radical scavenging activity, elastase inhibition activity and collagenase inhibition activity. CL was extracted with various solvents including water (CLW), 70% ethanol (CLE) and 70% acetone (CLA). The results showed that CLW, CLE, and CLA have the radical scavenging activity. In addition, we showed that CLW, CLE, and CLA have the elastase inhibition activity and collagenase inhibition activity. Consequently, the CL has a potent anti-wrinkle effect and it could be a useful cosmeceutical product for anti-aging purposes.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.6
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• pp.921-929
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• 2020

Objective: The aim of the present study was to investigate the beneficial effects of dietary supplementation with oil palm frond (leaf) (OPF) with and without oil palm meal (OPM) on nutrient intake and digestibility, ruminal fermentation and growth performance in goats. Methods: Six female crossbred goats were fed for 28 days of 3 diet treatments; 100% para-grass (T1); 50% para-grass + 50% OPF (T2), and 30% para-grass + 50% OPF + 20% OPM (T3). Body weight, rectal temperature, respiratory rate, and urine volume, food intake, dry matter intake and water intake were measured daily. Nutrient digestibility was determined from five consecutive days of last week in each diet. Ruminal fluid, urine and blood were collected at the end for determination of rumen protozoa and volatile fatty acid contents, urinary allantoin excretion, blood cell count and chemistry profiles. Results: Goats fed T2 and T3 showed higher dry matter and nutrients intakes while protein digestibility was suppressed compared with those for T1. Crude fat digestibility declined in T2 but maintained after adding the OPM (T3). High fat intake by giving OPF and OPM corresponded to a higher ruminal acetate/propionate ratio (C2/C3) and serum cholesterol level. An increased urinary allantoin/creatinine ratio was found in T2 and T3 compared with T1, implying an increased number of ruminal microbes. Conclusion: Increased dry matter intake in T2 and T3 suggested that oil palm by-products are partly useful as a replacement for para-grass in goats. Replacement with the by-products increased plasma cholesterol level, which suggested that these products are a useful energy source. Changes in rumen parameters suggested an increased microbial number and activity suitable for acetate production. However, the limited digestibility of protein implies that addition of high protein feeds may be recommended to increase body weight gain of goats.