• Korean Journal of Weed Science
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• v.30 no.4
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• pp.390-395
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• 2010

This study was conducted to predict reduction of soybean yield as affected by different densities of Cuscuta pentagona. All data were fitted to Cousens' rectangular hyperbola model to estimate parameters for predicting soybean yield loss. The yield of soybean in the various densities (1 to 48 plants $m^{-2}$) of C. pentagona reduced by 80.3 to 99.7%, respectively. Among yield components, number of pods was the most significantly influenced by weed interferences. The prediction model for soybean yield as affected by weed competition was as follows: Y= 274.6783/(1+4.3522X), $r^2$=0.999 in C. pentagona. Economic threshold levels calculated using cousens' equation was 0.004 plants $m^{-2}$ in C. pentagona.

• Korean Journal of Pharmacognosy
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• v.45 no.4
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• pp.332-337
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• 2014

The Salvia plebeia R. which is the biennial plant belonging to the labiatae department, grows widely in Korea. This study was performed to evaluate the antioxidant activities and anti-allergic effects of Salvia plebeia R. leaves (SPLE) or roots (SPRE). Using ethanol extracts, both leaves and roots induced significant radical scavenging activity against DPPH and ABTS radicals in a dose dependent manner (p<0.05). Superoxide dismutase (SOD)-like activity of SPLE was significantly higher than that of SPRE at all concentrations. Treatment of the RBL-2H3 cells with SPLE and SPRE in vitro decreased ${\beta}$-Hexosaminidase release and significantly inhibited IgE-antigen complex-mediated IL-4 and TNF-${\alpha}$ mRNA expression in RBL-2H3 cells. These findings suggest that Salvia plebeia R. can protect or reduce allergic asthma through high antioxidant and anti-allergic reactions.

• BMB Reports
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• v.45 no.1
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• pp.44-46
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• 2012

Recent advances in high-throughput genotyping technologies have enabled us to conduct a genome-wide association study (GWAS) on a large cohort. However, analyzing millions of single nucleotide polymorphisms (SNPs) is still a difficult task for researchers conducting a GWAS. Several difficulties such as compatibilities and dependencies are often encountered by researchers using analytical tools, during the installation of software. This is a huge obstacle to any research institute without computing facilities and specialists. Therefore, a proper research environment is an urgent need for researchers working on GWAS. We developed BioSMACK to provide a research environment for GWAS that requires no configuration and is easy to use. BioSMACK is based on the Ubuntu Live CD that offers a complete Linux-based operating system environment without installation. Moreover, we provide users with a GWAS manual consisting of a series of guidelines for GWAS and useful examples. BioSMACK is freely available at http://ksnp.cdc.go.kr/biosmack.

• Molecules and Cells
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• v.21 no.1
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• pp.147-152
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• 2006

Most plant organs develop from meristems. Rice FON1, which is an ortholog of Clv1, regulates stem cell proliferation and organ initiation. The point mutations, fon1-1 and fon1-2, disrupt meristem balance, resulting in alteration of floral organ numbers and the architecture of primary rachis branches. In this study, we identified two knockout alleles, fon1-3 and fon1-4, generated by T-DNA and Tos17 insertion, respectively. Unlike the previously isolated point mutants, the null mutants have alterations not only of the reproductive organs but also of vegetative tissues, producing fewer tillers and secondary rachis branches. The mutant plants are semi-dwarfs due to delayed leaf emergence, and leaf senescence is delayed. SEM analysis showed that the shoot apical meristems of fon1-3 mutants are enlarged. These results indicate that FON1 controls vegetative as well as reproductive development by regulating meristem size.

• Proceedings of the Korean Powder Metallurgy Institute Conference
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• 2006.09b
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• pp.790-791
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• 2006

The fracture behavior and mechanical characteristics of sintered rare-earth magnets were investigated. It shows that the fracture behavior and bending strength of the magnets obviously exhibit anisotropy. Sm-Co magnets tend to cleavage fracture in the close-packed (0001) plane or in the ($10\bar{1}1$) plane. The fracture mechanism of $Nd_2Fe_{14}B$ magnet mainly appears to be intergranular fracture. The anisotropy of fracture behavior and mechanical strength of sintered rare-earth magnets is caused mainly by the strong crystal-structure anisotropy and the grain alignment texture. The effects of Nd content, and Pr, Dy substitution on the impact stability of $Nd_2Fe_{14}B$ magnets were also reported.

• BMB Reports
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• v.45 no.1
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• pp.47-50
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• 2012

The International HapMap Project and the Human Genome Diversity Project (HGDP) provide plentiful resources on human genome information to the public. However, this kind of information is limited because of the small sample size in both databases. A Genome-Wide Association Study has been conducted with 8,842 Korean subjects as a part of the Korea Association Resource (KARE) project. In an effort to build a publicly available browsing system for genome data resulted from large scale KARE GWAS, we developed the KARE browser. This browser provides users with a large amount of single nucleotide polymorphisms (SNPs) information comprising 1.5 million SNPs from population-based cohorts of 8,842 samples. KAREBrowser was based on the generic genome browser (GBrowse), a web-based application tool developed for users to navigate and visualize the genomic features and annotations in an interactive manner. All SNP information and related functions are available at the web site http://ksnp.cdc. go.kr/karebrowser/.

• Journal of Magnetics
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• v.16 no.3
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• pp.304-307
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• 2011

High performance Nd-Fe-B magnets can be manufactured by both sintering and hot deformation. The corrosion behaviors of the magnets prepared by the two processes were compared. Effect of microstructure on the corrosion resistance of Nd-Fe-B magnets was also investigated. A neutral salt spray test (NSS) was performed for the different-processed magnets. The weight losses of the samples after the corrosion test were measured. The corrosion microstructures were observed using a scanning electron microscope. It shows that the corrosion resistance of hot deformed magnets is much better than that of the sintered ones because the grain size and the distribution of Nd-rich phases of the hot deformed magnets are much finer and more uniform than those of the sintered ones. The different microstructure between the sintered and the hot deformed magnets causes the different corrosion behavior.

• Journal of Magnetics
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• v.16 no.3
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• pp.294-299
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• 2011

Nd-Fe-B high performance magnets were prepared by die-upset forging. The effects of the deformation parameters on magnetic properties and flow stress were studied. Deformation temperatures in the range of $600{\sim}900^{\circ}C$ enable to achieve an effective anisotropy and temperature $800^{\circ}C$ proves to be suitable for deformation of Nd-Fe-B magnets. The amount of c-axis alignment along the press direction seems to depend on the amount of deformation and a saturation behavior is shown at deformation ratio of 75%. Magnetic properties are also related to strain rate, and maximum energy product is attained at an optimum strain rate of ${\varphi}=1{\times}10^{-2}s^{-1}$. By analyzing the relationship of stress and strain at different deformation temperature during die-upset forging process, deformation behavior of Nd-Fe-B magnets was studied and parameters for describing plastic deformation were obtained. Nd-rich boundary liquid phase, which is additionally decreasing the flow stress during deformation, is supposed to play the role of diffusion path and enhance the diffusion rate.

• Food Industry And Nutrition
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• v.22 no.1
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• pp.33-37
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• 2017

• BMB Reports
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• v.45 no.6
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• pp.365-370
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• 2012

Hepatitis B virus (HBV) DNA is often integrated into hepatocellular carcinoma (HCC). Although the relationship between HBV integration and HCC development has been widely studied, the role of HBV integration in HCC development is still not completely understood. In the present study, we constructed a pooled BAC library of 9 established cell lines derived from HCC patients with HBV infections. By amplifying viral genes and superpooling of BAC clones, we identified 2 clones harboring integrated HBV DNA. Screening of host-virus junctions by repeated sequencing revealed an HBV DNA integration site on chromosome 11q13 in the SNU-886 cell line. The structure and rearrangement of integrated HBV DNA were extensively analyzed. An inverted duplicated structure, with fusion of at least 2 HBV DNA molecules in opposite orientations, was identified in the region. The gene expression of cancer-related genes increased near the viral integration site in HCC cell line SNU-886.