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http://dx.doi.org/10.5483/BMBRep.2012.45.1.44

BioSMACK: a linux live CD for genome-wide association analyses  

Hong, Chang-Bum (Division of Structural and Functional Genomics, Center for Genome Science, National Institute of Health)
Kim, Young-Jin (Division of Structural and Functional Genomics, Center for Genome Science, National Institute of Health)
Moon, Sang-Hoon (Division of Structural and Functional Genomics, Center for Genome Science, National Institute of Health)
Shin, Young-Ah (Division of Structural and Functional Genomics, Center for Genome Science, National Institute of Health)
Go, Min-Jin (Division of Structural and Functional Genomics, Center for Genome Science, National Institute of Health)
Kim, Dong-Joon (Division of Structural and Functional Genomics, Center for Genome Science, National Institute of Health)
Lee, Jong-Young (Division of Structural and Functional Genomics, Center for Genome Science, National Institute of Health)
Cho, Yoon-Shin (Division of Structural and Functional Genomics, Center for Genome Science, National Institute of Health)
Publication Information
BMB Reports / v.45, no.1, 2012 , pp. 44-46 More about this Journal
Abstract
Recent advances in high-throughput genotyping technologies have enabled us to conduct a genome-wide association study (GWAS) on a large cohort. However, analyzing millions of single nucleotide polymorphisms (SNPs) is still a difficult task for researchers conducting a GWAS. Several difficulties such as compatibilities and dependencies are often encountered by researchers using analytical tools, during the installation of software. This is a huge obstacle to any research institute without computing facilities and specialists. Therefore, a proper research environment is an urgent need for researchers working on GWAS. We developed BioSMACK to provide a research environment for GWAS that requires no configuration and is easy to use. BioSMACK is based on the Ubuntu Live CD that offers a complete Linux-based operating system environment without installation. Moreover, we provide users with a GWAS manual consisting of a series of guidelines for GWAS and useful examples. BioSMACK is freely available at http://ksnp.cdc.go.kr/biosmack.
Keywords
GWAS; Human genome; Linux; Live CD; SNP;
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