• 한국산업보건학회지
• /
• 제15권1호
• /
• pp.27-35
• /
• 2005

This study was carried out to evaluate the characteristics of petroleum refinery workers' exposure to organic solvents. Exposure assessment was conducted by full shift-based long term personal sampling(TWA-P) and task-based short term personal sampling(STEL-P) strategy. Major organic solvents that workers can be exposed are various, varying from C3~C12, and this study focused on 11 kinds including benzene, considering toxicity and concentration level. In comparison with two sampling results, STEL-P shows a significant(p<0.001) excess of exposure level rather than TWA-P. As the potential risk index for benzene is calculated as 16, benzene should be set the highest priority for control in petroleum refinery industry. The tasks with the highest benzene exposure level were de-watering(AM;99.8 ppm), draining(AM;19.6ppm), sampling(AM;16.2ppm), and manual gauging(AM;15.02ppm). Petroleum refinery workers' exposure pattern to organic solvents differs by tasks performed, and some task has a high risk of temporary extreme exposure. Therefore, traditional 8-hour TWA sampling strategy have possibility of underestimation of exposure level of workers in petroleum refinery.

• Wind and Structures
• /
• 제25권2호
• /
• pp.195-214
• /
• 2017

Full-scale wind characteristics based on the field measurements is an essential element in structural wind engineering. Statistical analysis of the wind characteristics at Sutong Cable-stayed Bridge (SCB) site is conducted in this study with the recorded long-term wind data from structural health monitoring system (SHMS) between 2008 and 2015. Both the mean and turbulent wind characteristics and power spectra are comprehensively investigated and compared with those in the current codes of practice, such as the measured wind rose diagram, monthly maximum mean wind speed, turbulence intensity, integral length scale. Measurement results based on the monitoring data show that winds surrounding the SCB site are substantially influenced by the southeast monsoon in summer and strong northern wind in winter. The measured turbulence intensity is slightly higher than the recommended values in specifications, while the measured ratio of lateral to longitudinal turbulence intensity is slightly lower. An approximately linear relationship between the measured turbulence intensities and gust factors is obtained. The mean value of the turbulence integral length scale is smaller than that of typical typhoon events. In addition, it is found that the Kaimal spectrum is suitable to be adopted as the power spectrum for longitudinal wind component at the SCB site. This contribution would provide important wind characteristic references for the wind performance evaluation of SCB and other civil infrastructures in adjacent regions.

• 대한두경부종양학회지
• /
• 제29권2호
• /
• pp.48-50
• /
• 2013

Angiomyoma is a rare, benign smooth muscle cell tumor. These tumors may be found anywhere in the body. They frequently occur in the lower extremities except venous type. Angiomyoma in the head and neck area is very rare, and only a few cases have been reported. A 63 year-old male patient visited to outpatient clinic due to size-growing nodule-like lesion in the Lt. alar area. Excisional biopsy was done for diagnosis. The lesion was totally excised with 2 mm safety margin. Frozen biopsy of the lesion was requested, and all resection margins were proved negative. To cover the raw surface, full thickness skin grafting was performed. The graft was harvested from Rt. posterior auricular area. Tie over dressing was applyed on Lt. alar area. The graft was well taken and healed without any complication in both short term and long term follow up periods of 2 weeks, 1 month, 2 months, and 6 months. Donor site completed healed without any complications. The leiomyoma is benign tumor originated from smooth muscle, and it can be classified into solid leiomyoma, angiomyoma, and epithelioid leiomyoma. Especially, the angiomyoma consists of smooth muscle cell and blood vessel, and it is originated from the tunica media of blood vessel. Angiomyoma alone frequently occurs in the lower extremities as solitary painless subcutaneous tumor. Venous type of angiomyoma in the oral cavity was reported in other references, but on the facial surface it may be the first case reported as paper. So this report can be very meaningful.

• Molecules and Cells
• /
• 제22권2호
• /
• pp.168-174
• /
• 2006

Enhanced apoptosis has been observed in the placentas of women with preeclampsia, but few studies have examined changes at the molecular level. This study was designed to detect genes specifically expressed in full-term preeclamptic placentas. Tissue samples were collected immediately after cesarean delivery from 11 normal and 8 preeclamptic placentas at 35-40 weeks of gestation. Total RNAs were extracted and hybridized to a cDNA microarray. Results were confirmed by reverse-transcription polymerase chain reaction (RT-PCR), Western blotting and immunohistochemistry. Hematoxylin and eosin and TUNEL staining were also performed to confirm apoptosis in preeclamptic placentas. Among 205 genes, three were up- or downregulated in preeclamptic placentas. The expression of caspase-10 and death receptor 3 (DR-3) was significantly increased, whereas insulin-like growth factor binding protein-3 (IGFBP-3) was strongly downregulated. RT-PCR analysis and Western blotting confirmed these effects. Immunohistochemical analysis showed that the DR-3, caspase-10 and IGFBP-3 proteins were localized in the syncytial membrane. Apoptosis in the trophoblast was also increased in term placentas from women with pregnancies complicated by preeclampsia. These results suggest that caspase-10, DR-3 and IGFBP-3 are involved in apoptosis in the preeclamptic placenta.

• 정보화정책
• /
• 제24권1호
• /
• pp.48-78
• /
• 2017

본 연구에서는 공공데이터 개방수준에 미치는 요인을 알아보는 것은 물론 사회자본의 조절효과와 매개효과를 알아보기 위해 총 26개국을 대상으로 공공데이터 개방지수인 ODB와 OUR Index에 대한 다중회귀분석 및 경로분석을 진행하였다. 다중회귀분석결과 종속변수 ODB를 기준으로 할 때 독립변수만을 투입한 모델 1에서는 전자정부, SW시장규모, 정부효과성이 유의미한 정적인 영향을 보였다. 독립변수, 조절변수를 투입한 모델 2에서는 전자정부, SW시장규모, 사회자본이 유의미한 정적인 영향을 보였다. 독립변수, 조절변수, 상호작용항이 투입된 모델 3에서는 전자정부, 사회자본이 유의미한 정적인 영향을 보였다. 종속변수 OUR Index를 기준으로 할 때 모델 1, 모델2에서 전자정부만이 유의미한 정적인 영향을 보였다. 독립변수, 조절변수, 상호작용항이 투입된 모델 3에서는 전자정부, SW시장규모${\times}$사회자본이 유의미한 정적인 영향을 보였다. 경로분석에서는 종속변수 ODB의 대안모형에 대해서 정부효과성만이 사회자본과 완전매개효과를 나타냈다.

• 한방안이비인후피부과학회지
• /
• 제15권1호
• /
• pp.140-150
• /
• 2002

Introduction: Atopic dermatitis is chronic eczematous dermatosis which is related strongly to a family history of atopic disease and hereditary disposition. Its threshold of itching is low so that severe itching occurs and causes secondary eczema. Adult atopic dermatitis has mostly severe symptoms and progresses to chronic relapsing. Objective: The purpose of this study was to estimate the efficacy of oriental medical treatment and management on chronic adult atopic dermatitis. Subject: We studied 3 patients who visited Dongguk University Gangnam Oriental Hospital Dept. of Dermatol. with chronic adult atopic dermatitis from August 2001 to April 2002 and were observed for over 4 months. Methods: We treated them with herb-medication, acupuncture, negative therapy, aroma therapy, full spectrum visible ray therapy(by carbon arc) and external application(Jaun-go). We used the SCORAD index to assess the severity of atopic dermatitis. Results: There were 3 patients with chronic adult atopic dermatitis we could check for over 4 months by clinical scoring using the SCORAD system. 1. The grades of the severity of atopic dermatitis were lower only by the oriental medical treatments and management. 2. Intensities of relapse cases were lower then before the oriental medical treatments. 3. The secondary treatment term for relapse cases was shorter then the first treatment term after oriental remedies were used. Conclusion: Considering the above results, more study is needed on the chronic relapse cases with adult atopic dermatitis, the factors of increasing seventy of adult atopic dermatitis, the prognostic factors of adult atopic dermatitis, and the clinical interchange of chronic adult atopic dermatitis between oriental medicine and western medicine.

• 사상체질의학회지
• /
• 제21권1호
• /
• pp.35-43
• /
• 2009

1. Objectives This study is for comparing between theory about "Constitution" in China and Sasang constitutional Medicine in Korea 2. Method I refered to the literatures about "Constitution" published in China and Korea 3. Result and Conclusion 1) "Constitution" in Traditional Chinese Medcine(TCM) is reinterpretation of Traditional Chinese Medcine, while, Constitution in Sasang Constitutional Medicine is an innovative concept developed from Traditional Korean Medicine. 2) The concept of "Constitution" in Chinese Medicien is related to long-term-period symptom or physical condition, while, the concept of Constitution in Sasang Constitutional Medicien includes not only long-term-period symptoms or physical conditions but also natural superiority and inferiority of individual according to 4 type Constitution. 3) The concept of Constitution in Sasang Constitutional Medicien has organized mind-body system than Concept of "Constitution" in Chinese Medicine. According to the theory of Sasang Constitutional Medicine, Mind is one of the best important things related type of disease. Lectures of Sasang Constitutional Medicine give a full detail of correlation of Mind and disease. 4) Finally, The concept of "Constitution" in Chinese Medicien is changeable but the Concept of "Constitution" in Sasang Constitutional Medicien is not changeable. changeable elements in Sasang Constitutional Medicien are symptoms and syndromes of disease.

• Clinical and Experimental Pediatrics
• /
• 제63권6호
• /
• pp.219-225
• /
• 2020

Background: There is increasing concern that moderate preterm (32-33 weeks' gestation) and late preterm (34-36 weeks' gestation) birth may be associated with minor neurodevelopmental problems affecting poor school performance. Purpose: We explored the cognitive function, cognitive visual function, executive function, and behavioral problems at school age in moderate to late preterm infants. Methods: Children aged 7-10 years who were born at 32⁺⁰ to 36⁺⁶ weeks of gestation and admitted to the neonatal intensive care unit from August 2006 to July 2011 at the National Health Insurance Service Ilsan Hospital were included. We excluded children with severe neurologic impairments, congenital malformations, or chromosomal abnormalities. Neuropsychological assessments consisted of 5 neuropsychological tests and 3 questionnaires. Results: A total of 37 children (mean age, 9.1±1.2 years) participated. The mean gestational age at birth was 34.6±7.5 weeks, while the mean birth weight was 2,229.2±472.8 g. The mean full-scale intelligence quotient was 92.89±11.90; 24.3% scored between 70 and 85 (borderline intelligence functioning). An abnormal score was noted for at least one of the variables on the attention deficit hyperactivity disorder diagnostic system for 65% of the children. Scores below borderline function for executive quotient and memory quotient were 32.4% and 24.3%, respectively. Borderline or clinically relevant internalizing problems were noted in 13.5% on the Child Behavior Check List. There were no significant associations between perinatal factors or socioeconomic status and cognitive, visual perception, executive function, or behavior outcomes. Conclusion: Moderate to late preterm infants are at risk of developing borderline intelligence functioning and attention problems at early school age. Cognitive and executive functions that are important for academic performance must be carefully monitored and continuously followed up in moderate to late preterm infants.

• Smart Structures and Systems
• /
• 제12권3_4호
• /
• pp.415-426
• /
• 2013

Condition assessment and monitoring of bridges is critical for safe passenger travel, public transportation, and efficient freight. In monitoring, displacement measurement capability is important to keep track of performance of bridge, in part or as whole. One of the most important parts of a bridge is the expansion joint, which accommodates continuous cyclic thermal expansion of the whole bridge. Though expansion joint is critical for bridge performance, its inspection and monitoring has not been considered significantly because the monitoring requires long-term data using cost intensive equipment. Recently, a wireless smart sensor network (WSSN) has drawn significant attention for transportation infrastructure monitoring because of its merits in low cost, easy installation, and versatile on-board computation capability. In this paper, a rapid wireless displacement monitoring system, wireless hybrid sensor (WHS), has been developed to monitor displacement of expansion joints of bridges. The WHS has been calibrated for both static and dynamic displacement measurement in laboratory environment, and deployed on an in-service highway bridge to demonstrate rapid expansion joint monitoring. The test-bed is a continuous steel girder bridge, the Founders Bridge, in East Hartford, Connecticut. Using the WHS system, the static and dynamic displacement of the expansion joint has been measured. The short-term displacement trend in terms of temperature is calculated. With the WHS system, approximately 6% of the time has been spent for installation, and 94% of time for the measurement showing strong potential of the developed system for rapid displacement monitoring.

• Journal of Korean Neurosurgical Society
• /
• 제61권6호
• /
• pp.767-773
• /
• 2018

Three male patients diagnosed with surfer's myelopathy (19-30 years) were admitted to our hospital. All three patients were novice surfers showing a typical clinical course of rapid progression of paraplegia following the onset of back pain. Typical history and magnetic resonance imaging features indicated the diagnosis of surfer's myelopathy. Two patients received high-dose steroid therapy and the other was treated with induced hypertension. One patient treated with induced hypertension showed almost full recovery; however, two patients who received high-dose steroid therapy remained completely paraplegic and required catheterization for bladder and bowel dysfunction despite months of rehabilitation. Our case series demonstrates the potentially devastating neurological outcome of surfer's myelopathy; however, early recovery in the initial 24-72 hours of presentation can occur in some patients, which is in accordance with previous reports. Ischemic insult to the spinal cord is thought to play a crucial role in the pathophysiology of surfer's myelopathy. Treatment recommendations include hydration, induced hypertension, early spinal angiography with intra-arterial intervention, intravenous tissue plasminogen activator, and high-dose steroid therapy; however, there is no standardized treatment option available. Early recovery appears to be important for long-term neurological outcome. Induced hypertension for initial treatment can be helpful for improving spinal cord perfusion; therefore, it is important for early and long-term neurological recovery. Education and awareness are essential for preventing surfer's myelopathy and avoiding further deterioration of neurological function.