• Title/Summary/Keyword: Full Rate

Search Result 1,774, Processing Time 0.034 seconds

A Comparison of Discriminating Powers Between 14 Microsatellite markers and 60 SNP Markers Applicable to the Cattle Identification Test (소 동일성 검사에 적용 가능한 14 Microsatellite marker와 60 Single Nucleotide Polymorphism marker 간의 판별 효율성 비교)

  • Lim, Hyun-Tae;Seo, Bo-Yeong;Jung, Eun-Ji;Yoo, Chae-Kyoung;Yoon, Du-Hak;Jeon, Jin-Tae
    • Journal of Animal Science and Technology
    • /
    • v.51 no.5
    • /
    • pp.353-360
    • /
    • 2009
  • When 14 microsatellite (MS) markers were applied in the identifying test for 480 Hanwoo, the discriminating power was estimated as $3.43{\times}10^{-27}$ based on the assumption of a random mating group (PI). This rate is 1,000 times higher than that of 60 single nucleotide polymorphism (SNP) markers. On the other hand, the power of the 60 SNP markers was estimated as $4.69{\times}10^{-20}$ and $8.02{\times}10^{-12}$ on the assumption of a half-sib mating group ($PI_{half-sibs}$) and a full-sib mating group ($PI_{sibs}$), respectively. These powers were 10 times and 10,000 times higher than those of the 14 MS markers. The results indicated that the total number of alleles (MS vs SNP = 146 vs 120) acted as a key factor for the discriminating power in a random mating population, and the total number of markers (MS vs SNP = 14 vs 60) was a dominant influence on the power in half-sib and full-sib populations. In the Hanwoo population, in which it was assumed that the entire population is the enormous half-sib group formed by the absolute genetic contribution of a few nuclear bulls, there will be only a 10 times difference in the discriminating power between the 14 MS markers and the 60 SNP makers. However, the probability of not excluding a candidate parent pair from the parentage of an arbitrary offspring, given that only the genotype of the offspring ($PNE_{pp}$) was 1,000 times higher as shown by the 14 MS markers than that by the 60 SNP markers. The strong points of SNP makers are the stability of the variation (low mutation rate) and automation of high-throughput genotyping. In order to apply these merits for the practical and constant Hanwoo identity test, research and development are required to set a cost-effective platform and produce a homemade apparatus for SNP genotyping.

Geographic Variation of Seed Characteristics and 1-year-old Seedling Growth of Zelkova serrata (느티나무 종자특성의 지리적 변이와 1년생 유묘의 생장)

  • Kim, In Sik;Lee, Joo Hwan
    • Korean Journal of Agricultural and Forest Meteorology
    • /
    • v.15 no.4
    • /
    • pp.234-244
    • /
    • 2013
  • This study was conducted to determine the factors affecting to seed characteristics and seedling growth of Zelkova serrata. The seeds were collected from sixteen populations of Z. serrata and the seed characteristics (i.e., seed length, width, weight and full seed rate) were measured. We also measured the 1-year-old seedling growth of each population at nursery. All seed characteristics showed significant differences in population level. Seed length and seed width were positively correlated with latitude, longitude, altitude and distance from coast line of sampling site. Seed length and seed width also negatively correlated with annual mean temperature, mean temperature of growing season (Mar.~Oct.). The ratio of seed length/seed width showed inverse trend in case of seed length and seed width. Seed weight/1,000 grains had no correlation with geographic factors but showed negative correlation with annual mean dryness index. Seed weight/L showed negative correlation with latitude and longitude and positive correlation with mean temperature of growing season of sampling site. Full seed rate showed negative correlation with latitude, longitude and annual mean dryness index of sampling site. There were significant differences among populations, among family within population and among individuals within family in seedling growth. Height and diameter of root collar of seedling showed negative correlation with longitude and mean humidity of growing season of sampling site. Height growth of seedlings was not correlated with any seed characteristics but, diameter at root collar showed low negative correlation with seed weight/1,000 grains and seed weight/L. We discussed the implications of the results in view of tree improvement of Z. serrata.

An Experimental Study on the Seismic Performance of Shear Connections and Rib Plate H Beam to Column Connections (전단접합 및 리브 플레이트로 보강한 H형 보-기둥 접합부의 내진성능에 관한 실험적 연구)

  • Oh, Kyung Hyun;Seo, Seong Yeon;Kim, Sung Yong;Yang, Young Sung;Kim, Kyu Suk
    • Journal of Korean Society of Steel Construction
    • /
    • v.17 no.5 s.78
    • /
    • pp.569-580
    • /
    • 2005
  • The postbeam joint connection of the existing steel structure moment flexible frame system did not produce sufficient seismic resistance during the earthquakes in Northridge and Kobe, and it sustained brittle fracturing on the joint connection. This study was performed to execute the high-tensile bolt share connection of H-beams web and the full-scale experiment as a parameter of the existing reinforcement of H-flange rib, by making the shape of the existing joint connection. This experiment was performed to determine the extent of the decrease of the number of high-tensile bolts and how to improve workability of the two-phase shear connection of web beam. In addition, this study was performed to enhance the seismic resistant capacity through the enforcement of rib plates. As a result of the experiment of two-phase shear connection of H-beam web and of joint connection to be reinforced by rib plates, the results of this study showed that the initial stiffness, energy-dissipation capacity, and rotational capacity of plasticity was higher than the existing joint connection. As to the rate of increasing the strength and deformation capacity, there were differences between the tension side and compression side because of the position of shear tap. However, as a whole, they have shown excellent seismic resistant capacity. Also, all the test subjects exceeded 4% (rate of delamination), about 0.029 rad (total plastic capacity), and about 130% (maximum strength of joint connection) of fully plastic moment for the original section. Accordingly, this study was considered as it would be available in the design more than the intermediate-level of moment flexible frame.

Effects of one-to-one Labor Support on Labor Pain, Labor Stress Response, Childbirth Experience and Neonatal Status for Primipara (일대일 분만지지간호가 초산모의 분만동통, 분만스트레스 반응, 분만경험 및 신생아 상태에 미치는 효과)

  • Hur, Myung-Haeng
    • Women's Health Nursing
    • /
    • v.7 no.2
    • /
    • pp.188-202
    • /
    • 2001
  • This study was designed to investigate the effect of one-to-one labor support on labor pain, labor stress response, childbirth experience and neonatal status for primipara by a quasi experiment (nonequivalent control group pretest-posttest design), from April 30, 1999 to February 20, 2000. The subjects of this experiment consisted of eighty two primipara with single gestation, full term, uncomplicated pregnancies. Forty one were in the experimental group and forty one in the control group. Their mean age was 25.95 years, their mean gestation period was 39.9 weeks. A caring package of one-to-one labor support had three components. Physical support consisted of massage, back pressure, touch. Emotional support was provided by a continuous nurse's presence, acceptance and encouragement. Informational support involved teaching breathing skills, relaxation skills and knowledge about the labor process. Data assessed labor pain, pulse rate and blood pressure to measure labor stress response. Also, in measuring the value of labor stress response, plasma epinephrine, plasma norepinephrine and serum cortisol were measured. In the 24 hours after birth, the data for the postpartum mother's childbirth experiences was collected. Umbilical cord arterial blood pH, one minute and five minute Apgar score were measured after birth. Data was analyzed by t-test, $x^2$-test, repeated measures ANOVA, ANCOVA with SAS Program. The results were as follows; 1. Labor pain was significantly low in the experimental group(P=.016). 2. No significant group effects were found, but significant time effects were found for plasma epinephrine, norepinephrine, serum cortisol, pulse rate and blood pressure. 3. The childbirth experience of the experimental group was significantly more positive than the control group (P = .005). 4. The umbilical cord arterial blood pH of the experimental group was significantly higher than the control group(P=.014). There was no significant difference between the two groups in neonatal one minute and five minute Apgar scores. In conclusion, these findings indicate that one-to-one labor support could be effective in decreasing labor pain, and increasing positive childbirth experiences, also increasing the neonatal umbilical cord arterial blood pH for primipara. So, one-to-one labor support could be applied as an effective nursing treatment for primipara.

  • PDF

Effects of Induced Dioptric Blur on Visual Acuity and Contrast Sensitivity (유발된 광학적 흐림이 시력과 대비감도에 미치는 영향)

  • Kim, Chang-Jin;Choi, Eun Jung
    • Journal of Korean Ophthalmic Optics Society
    • /
    • v.19 no.2
    • /
    • pp.261-270
    • /
    • 2014
  • Purpose: To study the effect of an artificially induced dioptric blur on acuity and contrast sensitivity using the $Optec^{(R)}$ 6500. Methods: Healthy 31 subjects aged $22.90{\pm}1.92$ (male 16, female 15) who were recruited from university students with 6/6 (20/20) or better corrected visual acuity and normal binocularity. They were measured objective and subjective refraction for full correction and dioptric blur using 0.00 ~ +3.00 D (+0.50 D steps) trial lenses and trial frame. They were measured binocularly visual acuity and contrast sensitivity with the $Optec^{(R)}$ 6500 (Stereo Optical Co., Inc., Chicago, Illinois, USA) under day conditions (photopic condition, $85cd/m^2$). Results: The higher dioptric blur, the less distance visual acuity and decrease rate of visual acuity. The higher dioptric blur, the less contrast sensitivity at all frequencies, and the peak of contrast sensitivity was shifted from middle frequency (6 cpd) to low frequency (1.5 cpd). When the visual acuity was best visual acuity to 0.77, there was the peak point at 6 cpd which was normal contrast sensitivity peak point. Conclusions: If the low refractive error is uncorrected or the refractive error is inappropriate, the contrast sensitivity is decreased and the peak point of contrast sensitivity frequency is shifted abnormally though small uncorrected refractive error. So it will be considered that regular eye test and decision of refractive error correction is important.

Plasma-Assisted Molecular Beam Epitaxy of InXGa1-XN Films on C-plane Sapphire Substrates (플라즈마분자선에피탁시법을 이용한 C-면 사파이어 기판 위질화인듐갈륨박막의 에피탁시 성장)

  • Shin, Eun-Jung;Lim, Dong-Seok;Lim, Se-Hwan;Han, Seok-Kyu;Lee, Hyo-Sung;Hong, Soon-Ku;Joeng, Myoung-Ho;Lee, Jeong-Yong;Yao, Takafumi
    • Korean Journal of Materials Research
    • /
    • v.22 no.4
    • /
    • pp.185-189
    • /
    • 2012
  • We report plasma-assisted molecular beam epitaxy of $In_XGa_{1-X}N$ films on c-plane sapphire substrates. Prior to the growth of $In_XGa_{1-X}N$ films, GaN film was grown on the nitride c-plane sapphire substrate by two-dimensional (2D) growth mode. For the growth of GaN, Ga flux of $3.7{\times}10^{-8}$ torr as a beam equivalent pressure (BEP) and a plasma power of 150 W with a nitrogen flow rate of 0.76 sccm were fixed. The growth of 2D GaN growth was confirmed by $in-situ$ reflection high-energy electron diffraction (RHEED) by observing a streaky RHEED pattern with a strong specular spot. InN films showed lower growth rates even with the same growth conditions (same growth temperature, same plasma condition, and same BEP value of III element) than those of GaN films. It was observed that the growth rate of GaN is 1.7 times higher than that of InN, which is probably caused by the higher vapor pressure of In. For the growth of $In_xGa_{1-x}N$ films with different In compositions, total III-element flux (Ga plus In BEPs) was set to $3.7{\times}10^{-8}$ torr, which was the BEP value for the 2D growth of GaN. The In compositions of the $In_xGa_{1-x}N$ films were determined to be 28, 41, 45, and 53% based on the peak position of (0002) reflection in x-ray ${\theta}-2{\theta}$ measurements. The growth of $In_xGa_{1-x}N$ films did not show a streaky RHEED pattern but showed spotty patterns with weak streaky lines. This means that the net sticking coefficients of In and Ga, considered based on the growth rates of GaN and InN, are not the only factor governing the growth mode; another factor such as migration velocity should be considered. The sample with an In composition of 41% showed the lowest full width at half maximum value of 0.20 degree from the x-ray (0002) omega rocking curve measurements and the lowest root mean square roughness value of 0.71 nm.

Effect of Genotype on Whole-body and Intestinal Metabolic Response to Monensin in Mice

  • Fan, Y.K.;Croom, W.J.;Daniel, Linda;McBride, B.W.;Koci, M.;Havenstein, G.B.;Eisen, E.J.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.19 no.4
    • /
    • pp.554-562
    • /
    • 2006
  • Two lines of mice, M16 selected for rapid growth and a randomly selected control ICR as well as their reciprocal crosses were used to study the effects of genotype on whole-body energetics and intestinal responses to monensin. Six mice, eight weeks of age, from each line or reciprocal cross were assigned to one of two treatments, 1) drinking water containing 20 mmol/L monensin dissolved in 0.5% V/V ethanol, and 2) drinking water containing 0.5% V/V ethanol (control) for two weeks. After 11 days (age of 9 weeks and 4 days), whole-body $O_2$ consumption was measured. At the end of two weeks, jejunal $O_2$ consumption, intestinal tissue composition and histomorphometrics as well as the rate and efficiency of glucose absorption were estimated. In comparison with the control, monensin administration in drinking water resulted in less daily water intake (13.4 vs. 15.5 ml/mouse, p<0.01), less protein to DNA ratio of jejunal mucosa (5.41 vs. 6.01 mg/mg, p<0.05), lower villus width (88 vs. $100{\mu}m$, p<0.05), and less jejunal tissue $O_2$ consumption enhancement by alcohol (7.2 vs. 10.5%, p<0.01) in mice. Other than those changes, monensin had little (p>0.05) effect on variables measured in either line of mice or their reciprocal cross. In contrast, the M16 line, selected for rapid growth, as compared to the ICR controls or the reciprocal crosses, had less initial (pre-monensin treatment) whole-body $O_2$ consumption per gram of body weight (1.68 vs. $2.11-2.34{\mu}mol/min{\cdot}g$ BW, p<0.01) as compared to the ICR and reciprocal crosses. In addition, the M16 mice exhibited greater growth (412 vs. 137-210 mg/d, p<0.05), better feed efficiency (41.7 vs. 19.9-29.3 mg gain/g feed, p<0.05), shorter small intestines adjusted for fasted body weight (1.00 vs. 1.22-1.44 cm/g FBW, p<0.05), wider villi (109 vs. $87-93{\mu}m$, p<0.05), more mature height of enterocytes (28.8 vs. $24.4-25.1{\mu}m$, p<0.05) and a lower rate (91 vs. $133-145{\eta}mol\;glucose/min{\cdot}g$ jejunum, p<0.05) and less energetic efficiency (95 vs. $59-72{\eta}mol$ ATP expended/${\eta}mol$ glucose uptake, p<0.05) of glucose absorption compared to the ICR line and the reciprocal cross. Monensin had little (p>0.05) effect on whole-body $O_2$ consumption and jejunal function, whilst selection for rapid growth resulted in an apparent down-regulation of intestinal function. These data suggest that genetic selection for increased growth does not result in concomitant changes in intestinal function. This asynchrony in the selection for production traits and intestinal function may hinder full phenotypic expression of genotypic growth potential.

FUNCTIONAL RECONSTRUCTION OF MANDIBULAR DEFECTS WITH FREE BONE GRAFT (유리골 이식을 통한 하악골 결손부의 기능적 재건술)

  • Kim, Jong-Won;Nam, II-Woo;Kim, Myung-Jin;Choung, Pill-Hoon;Seo, Byung-Moo;You, Jun-Young;Nam, Ki-Weon;Song, Min-Seok
    • Maxillofacial Plastic and Reconstructive Surgery
    • /
    • v.15 no.4
    • /
    • pp.338-345
    • /
    • 1993
  • Mandibular discontinuity defect due to benign tumor, malignant tumor, infection, or truma results in major esthetic and biologic compromise. The primary goal of reconstruction is full restitution of function, which secondarily lead to normalization of the cosmetic deformity. The authors make a clinical study of 61 consecutive bone graft cases for mandibular reconstruction of discontinuity defect which were studied retrospectively using clinical data and radiographic findings. The cases were reviewed to evaluate the clinical success in the period from 1981 to 1990 in the Dept. of Oral & maxillofacial Surgery, Seoul National University Hospital. The criteria of the success in bone graft, are no residual infection, graft in with maintain its integrity, and remain over a half of its original size of graft in the radiographic features. The purpose of this clinical survey is to study of the mandibular discontinuity defects and success rate of free bone graft in mandibular defects. To summarize the clinical study of free bone graft, the main type of autogenous bone graft is iliac bone and corticocancellous type. Overall success rate is 80.3% in 61 followup cases over 6 months. Wire fixation and Extraoral approach has realtively better prognosis than other methods. It showed relatively poor prognosis in symphysis defects than other recipient site.

  • PDF

Distant Metastases of Nasopharyngeal Carcinoma after Definite Irradiation (근치적 방사선 치료를 받은 비인강암 환자의 원격전이 빈도 및 양상에 관한 고찰)

  • Chung Eun Ji;Lee Hyung Sik;Moon Sun Rock;Kim Gwi Eon;Loh John Juhn-Kyu
    • Radiation Oncology Journal
    • /
    • v.9 no.1
    • /
    • pp.65-72
    • /
    • 1991
  • One hundred and thirty five patients with carcinoma of the nasopharyx were treated by radiation therapy in the Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University between August 1977 and July 1987. Of the 30 patients omitted: 8 had distant metastases at initial diagnosis or during radiotherapy; 18 Patients refused or did not receive a full course of radiation therapy, and four had not been confirmed histologically. The remaining 105 patients were analysed to determine the incidence and pattern of distant metastases. Diagnosis of distant metastases was made based on clinical signs and radiography, even though histologic confirmation was not made. Twenty-six patients developed distant metastases after definite irradiation of nasopharyx and neck, an incidence rate of $24.8\%$ . The common sites of distant metastases were, in descending order, bone, lung, liver, and brain. There was a strong correlation between Ho's N stage and distant metastases rate. But sex, age, histologic subtype (squamous cell and undifferentiated cell), AJC T and N stage, treatment modalities (radiotherapy alone and radiotherapy combined with chemotherapy) were not significant. Of those patients who developed distant metastases, $80.8\%$ were discovered within 2 years of their radical radiotherapy. The prognosis for nasopharyngeal carcinoma patients developing distant metastases was poor: median survival was nine months and $80\%$ of those patients died within two years of the initial diagnosis of distant metastasis.

  • PDF

Preliminary Nitrogen Removal Rates in Close-to-Nature Constructed Stream Water Treatment Wetland (하천수정화 근자연형 인공습지의 초기 질소제거)

  • Yang, Hong-Mo
    • Korean Journal of Environmental Agriculture
    • /
    • v.21 no.4
    • /
    • pp.269-273
    • /
    • 2002
  • A 0.19 hectare stream water purification demonstration wetland was constructed and planted with cattails from April 2001 to May 2001. Some portions of its bottom surfaces adjacent to levees have a variety of slope of 1:4 $\sim$ 1:15 and two small open water areas were installed in the wetland. These make its shape closer to a natural wetlant Nitrogen removal was a major objective of the wetlant Waters of Sinyang Stream flowing into Kohung Esturiane Lake located southern coastal region of Korean Peninsula were pumped and funneled into it. Volumes and water quality of inflow and outflow were analyzed from July 2001 through December 2001. Average inflow and outflow were 120 $m^3/d$ and 112 $m^3/d$, respectively. Hydraulic retention time was about 3.1 days. Average nitrate and total nitrogen removal rate for the early stage of the wetlands were 85.8 $mg/m^2/day$, 171.4 $mg/m^2/day$ respectively. Full establishment of cattails within a few years can develope litter-soil substrates and supply available carbon sources beneficial to the denitrification of nitrate. These can lead to increases of the nitrate retention rate. Short circuiting and dead zone areas which might be occurred due to the close-to-nature layout of the wetland were not observed during the monitoring period.