• Steel and Composite Structures
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• 제42권2호
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• pp.277-288
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• 2022

A novel flat steel plate-concrete-corrugated steel plate (FS-C-CS) sandwich panel was proposed for resisting impact load. The failure mode, impact force and displacement response of the FS-C-CS panel under impact loading were studied via drop-weight impact tests. The combined global flexure and local indentation deformation mode of the FS-C-CS panel was observed, and three stages of impact process were identified. Moreover, the effects of corrugated plate height and steel plate thickness on the impact responses of the FS-C-CS panels were quantitatively analysed, and the impact resistant performance of the FS-C-CS panel was found to be generally improved on increasing corrugated plate height and thickness in terms of smaller deformation as well as larger impact force and post-peak mean force. The Finite Element (FE) model of the FS-C-CS panel under impact loading was established to predict its dynamic response and further reveal its failure mode and impact energy dissipation mechanism. The numerical results indicated that the concrete core and corrugated steel plate dissipated the majority of impact energy. In addition, employing end plates and high strength bolts as shear connectors could prevent the slip between steel plates and concrete core and assure the full composite action of the FS-C-CS panel.

• Natural Product Sciences
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• 제28권3호
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• pp.138-142
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• 2022

Alzheimer's disease (AD) is the most common age-related neurodegenerative disease in industrialized countries. It is estimated that about 47 million people living with dementia and the number of cases will be tripled by 2050. However, the exact mechanism of AD is not known, and full therapy has still not been found. Various tryptophan-derived alkaloids have been reported as promising agents for the treatment of AD. In the present study, a series of tryptophan-derived alkaloids were isolated and characterized from the methanol extract of Hedera rhombea fruit. Based on the analysis of their observed and reported spectroscopic data, their structures were identified as N-[4'-hydroxy-(E)-cinnamoyl]-L-tryptophan (1), N-[3',4'-dihydroxy-(E)-cinnamoyl]-L-tryptophan (2), N-[4'-hydroxy-(E)-cinnamoyl]-L-tryptophan methyl ester (3), and N-[3',4'-dihydroxy-(E)-cinnamoyl]-L-tryptophan methyl ester (4). These compounds were screened for anti-Alzheimer activity via their inhibition of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes in vitro. As a result, compounds 3 and 4 showed moderate BChE inhibition with IC₅₀ values of 86.9 and 78.4 μM, respectively, compared to those of the positive control [berberine (IC₅₀ = 11.5 μM)]. However, all four compounds did not show significant inhibition of the AChE enzyme. This is the first time, the AChE and BChE inhibitory activities of these tryptophan-derived alkaloids were investigated and reported.

• International Journal of Computer Science & Network Security
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• 제22권11호
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• pp.157-162
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• 2022

Cerebral palsy is one of the most serious forms of disorders of the psychophysical development of children, which manifests itself in disturbances of motor functions, which are often combined with speech disorders, other complications of the formation of higher mental functions, and often with a decrease in intelligence. The article will discuss the speech disorder in children with cerebral palsy. Emphasis is placed on some important aspects, which should bear in mind, investigating the problem of specifics of speech development of children with cerebral palsy. In particular at the heart of speech disorders in the cerebral palsy is not only damage to certain structures of the brain, but also the later formation or underdevelopment of those parts of the cerebral cortex, which are of major importance in linguistic and mental activity. This is an ontogenetically young region of the cerebral cortex, which is most rapidly developing after birth (premotor, frontal, temmono-temporal). It is important to take into account, that children with cerebral palsy have disturbances of phonemic perception. Often, children do not distinguish between hearing sounds, cannot repeat component rows, allocate sounds in words. At dysarthria, there are violations of pronunciation of vowel and consonant sounds, tempo of speech, modulation of voice, breathing, phonation, as well as asynchronous breathing, alignment and articulation. As a result, we identified the main features and specifics of the speech development of children with cerebral palsy and described the conditions necessary for the full development of language. Language disturbances in children's cerebral palsy depend on the localization and severity of brain damage. Great importance in the mechanism of speech disorders has a pathology that limits the ability of movement and knowledge of the world.

• 항공우주시스템공학회지
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• 제16권5호
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• pp.26-34
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• 2022

정지궤도위성의 추진시스템은 전이궤도에서 궤도상승, 정상 운영모드에서 남/북방향, 동/서방향 궤도위치유지 및 모멘텀 덤핑을 위해 일반적으로 사용된다. 최근 정지궤도위성에 완전 전기추진시스템을 적용할 경우 화학추진시스템 보다 탑재체의 탑재용량이 약 40% 증가 할 수 있어 정지궤도 위성에 전기추진시스템의 활용이 점차 증가 되고 있다. 그러나 이러한 장점에도 불구하고 전기추진시스템의 사용이 모든 정지궤도위성에 적용하기에는 여러 제약 조건이 있어 위성 임무에 따라 이에 적합한 추진시스템을 적용하여 왔다. 본 연구에서는 완전 전기추진시스템 적용한 국내 정지궤도위성 개발 시 고려되어야 할 정지궤도위성의 운영제약조건 분석, 전기추력기에 의한 오염영향, 방사선 노출에 따른 부품배치 고려 및 제어메카니즘 설계, 전기추력기용 고전압 제어유닛의 부동접지 설계방안들이 분석되었다.

• Wind and Structures
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• 제36권4호
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• pp.221-236
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• 2023

The lateral component of turbulence and the vortices shed in the wake of a structure result in introducing dynamic wind load in the acrosswind direction and the resulting level of motion is typically larger than the corresponding alongwind motion for a dynamically sensitive structure. The underlying source mechanisms of the acrosswind load may be classified into motion-induced, buffeting, and Strouhal components. This study proposes a frequency domain framework to decompose the overall load into these components based on output-only measurements from wind tunnel experiments or full-scale measurements. First, the total acrosswind load is identified based on measured acceleration response by solving the inverse problem using the Kalman filter technique. The decomposition of the combined load is then performed by modeling each load component in terms of a Bayesian filtering scheme. More specifically, the decomposition and the estimation of the model parameters are accomplished using the unscented Kalman filter in the frequency domain. An aeroelastic wind tunnel experiment involving a tall circular cylinder was carried out for the validation of the proposed framework. The contribution of each load component to the acrosswind response is assessed by re-analyzing the system with the decomposed components. Through comparison of the measured and the re-analyzed response, it is demonstrated that the proposed framework effectively decomposes the total acrosswind load into components and sheds light on the overall underlying mechanism of the acrosswind load and attendant structural response. The delineation of these load components and their subsequent modeling and control may become increasingly important as tall slender buildings of the prismatic cross-section that are highly sensitive to the acrosswind load effects are increasingly being built in major metropolises.

• 한국IT서비스학회지
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• 제22권1호
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• pp.75-93
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• 2023

The game industry has grown not only by combining them with various technologies also introducing new types of business models such as P2P, F2P, and P2W. Furthermore, games which implemented X2E model with blockchain technology are recently in the spotlight of the public attention. As domestic game companies have also prospect the blockchain games feasible, they are seeking ways to expand their global market share by strengthening the X2E model. Hence, by carrying this new business model out, it is expected to diversify their global revenue stream, which was previously confined to Asia region. This study analyzed the case of companies that have implemented the P2E and C2E models in order to suggest the direction of development for the game platform in Web 3.0 era. The cases of P2E game platform, which constitute of Axie Infinity and Mir 4, encompass the compensation structure, the stabilization mechanism of the in-game token economy, and future strategies regarding blockchain gaming. Likewise, the platform structure, business model, and future growth potential was discussed in terms of C2E scheme, focusing on the ZEPETO and Roblox cases. Based on the above case analysis, this study attempted to provide information on the current limitations and development directions of the P2E and C2E platforms. The current limitations in legal and industrial aspects should be addressed to facilitate the blooming of blockchain and P2E game industry. In addition, the necessity of not only social support also improvement on the technology and social stigma of full-time creators is ought to be emphasized in an effort to encourage the development of C2E platforms.

• 한국지반공학회논문집
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• 제23권1호
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• pp.5-11
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• 2007

최근 사용이 증가 추세에 있음에도 불구하고 마이크로파일의 하중전이곡선에 관한 연구는 매우 미미한 실정이다. 이에 본 연구에서는 국내지반 및 시공조건이 반영된 실물크기의 시험말뚝에 대한 현장시험을 실시하여 마이크로파일의 주면하중전이곡선을 산정하는 경험식을 제안하였다. 말뚝재하시험 결과로부터 깊이별 하중전이곡선을 구하고, 이를 쌍곡선 함수형태로 전환 시킨 후, 하중전이함수와 지반의 표준관입시험 저항치(N)와의 관계를 정립하였다. 이러한 일련의 과정을 거친 결과를 토대로 유한차분법과 문헌자료를 활용하여 개발된 하중전이함수로부터 풍화토에서 마이크로파일의 주면마찰력을 추정할 수 있음을 평가하였다.

• 한국지반공학회논문집
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• 제24권7호
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• pp.51-60
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• 2008

본 논문은 기초의 거동에 영향을 주는 여러 가지 인자 중 특히, 기초형상에 변화를 주었을 경우 기초의 거동에 초점을 두고 연구하였다. 시초형상으로는 시공성 및 경제성이 가장 우수하다고 판단되는 Shell기초 형태를 제시하였고 수치해석 및 실내모형시험을 실시하여 도출한 결과 값과 Terzaghi, Meyerhof등의 이론값을 비교 분석하였다. 그 결과, 일반기초에 비해 Shell 기초의 침하는 15%정도 크게 발생되는 것으로 나타났으나, 지지력은 $20%{\sim}25% 정도 향상되는 결과를 얻었다. 특히 Shell 기초 $60^{\circ}$인 경우 일반 기초에 비해 33%의 지지력이 향상되는 것을 알 수 있었으므로 연구된 기초형상이 실용화 되면 경제성과 안정성이 확보된 기초 설계기술에 공헌할 것으로 기대 된다.

• 한국지반공학회논문집
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• 제22권12호
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• pp.45-55
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• 2006

본 논문에서는 우리나라 태안지역에서 총 30회 수행한 암반앵커 현장시험의 결과를 나타내었다. 대상암반은 편마암으로써 풍화가 심한 것부터 신선한 암에 이르기까지 다양하며, 시험앵커의 깊이는 $1{\sim}4m$로 설치하였다. 앵커는 SD4O-D51mm를 사용함으로써 다른 파괴가 일어나기 전에 암반파괴가 먼저 일어나도록 유도하여 암반의 인발지지력을 파악하고자 하였다. 많은 시험에서 파괴는 극한하중까지 이르는 것을 관찰할 수 있었으며, 암반파괴형상은 암반이 들어올려지면서 방사상으로 균열이 발달하는 형상을 나타내었다. 시험결과, 암반앵커의 인발지지력은 암반의 종류, 암질, 앵커의 정착깊이, 앵커텐던의 인장강도 등에 영향을 받는 것으로 나타났다. 본 시험을 통해 암반앵커시스템의 인발지지력을 지배하는 주요파라메터들을 도출하고 이에 대해 논하였다.

• 대한토목학회논문집
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• 제28권6A호
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• pp.819-825
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• 2008

이 논문은 케이블텐션을 이용해서 SCST 구조의 형상 형성과 시공에 대해 연구한 논문인데, 이 공법은 균일한 모양의 피라미드로 만들어진 공간구조를 신속하고 경제적으로 시공할 수 있는 공법이 될 수 있다. 초기의 배치에 있어서 상현재와 웨브부재는 일정한 길이이나 하현재는 원하는 최종적인 형상에 비례해서 갭이 주어져 있다. 본 연구에서 제안된 형상 형성법의 적용성과 신뢰성은 축소된 모델과 실물 크기의 실험 모델에 대한 비선형 유한요소 해석과 실험적인 조사를 통해 확인할 수 있다. 연구의 결과, MERO 조인트의 거동 특성은 공간 구조의 형상 해석에서 매우 중요하며 본 논문은 실무에서 형상을 예측할 수 있는 가장 적합한 모델링 기법을 제시하고 있다. 그리고 실제 설계에 필요한 형상 실험의 거동 특성을 보여 주고 있다.