• 제목/요약/키워드: Fujimoto

검색결과 101건 처리시간 0.026초

Study of moxibustion stimulation in the ovariectomized rat model

  • Kanai, Shigeyuki;Taniguchi, Norimasa;Kanda, Kayo;Matsuhata, Izuru
    • Advances in Traditional Medicine
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    • 제5권3호
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    • pp.195-200
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    • 2005
  • In order to examine the effectiveness of moxibustion stimulation for climacteric disturbance, we administered moxibustion stimulation to ovariectomized (OVX) rats, and compared the tail surface temperature, laboratory parameters, and the level of locomotor activity with those of untreated rats. Twenty-four female Wistar rats (8 weeks old, 160 - 180 g) were divided into three groups. The rats in the OVX-M group underwent moxibustion stimulation after ovariectomy. The rats in the OVX-C group underwent ovariectomy but did not receive moxibustion stimulation. The rats in the Normal group received neither ovariectomy nor moxibustion stimulation. The level of locomotor activity was determined by a metabolism measuring system. The tail surface temperature was significantly lower in the OVX rats before moxibustion stimulation than in the Normal group. In the OVX rats before moxibustion stimulation, there was no clear difference in the level of locomotor activity between the active and resting phases, and the pattern of locomotor activity was irregular. After moxibustion stimulation, the tail surface temperature of the OVX-M group did not significantly differ from that of the Normal group, and the pattern of locomotor activity of the OVX-M group became diphasic with clear active and resting phases, similar to that observed in the Normal group. These results demonstrate that moxibustion stimulation is effective for the treatment of climacteric disturbance.

Computational Soil-Structure Interaction Design via Inverse Problem Formulation for Cone Models

  • Takewaki, Izuru;Fujimoto, Hiroshi;Uetani, Koji
    • Computational Structural Engineering : An International Journal
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    • 제2권1호
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    • pp.33-42
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    • 2002
  • A computationally efficient stiffness design method for building structures is proposed in which dynamic soil-structure interaction based on the wave-propagation theory is taken into account. A sway-rocking shear building model with appropriate ground impedances derived from the cone models due to Meek and Wolf (1994) is used as a simplified design model. Two representative models, i.e. a structure on a homogeneous half-space ground and a structure on a soil layer on rigid rock, are considered. Super-structure stiffness satisfying a desired stiffness performance condition are determined via an inverse problem formulation for a prescribed ground-surface response spectrum. It is shown through a simple yet reasonably accurate model that the ground conditions, e.g. homogeneous half-space or soil layer on rigid rock (frequency-dependence of impedance functions), ground properties (shear wave velocity), depth of surface ground, have extensive influence on the super-structure design.

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Multivariate Optimization of a Sulfated- β-Cyclodextrin-Modified Capillary Zone Electrophoretic Method for the Separation of Chiral Arylalcohols

  • Zhang, Yu-Ping;Noh, Hyun-Joo;Choi, Seong-Ho;Ryoo, Jae-Jeong;Lee, kwang-Pill;Ohta, Kazutoku;Fujimoto, Chuzo;Jin, Ji-Ye;Takeuchi, Toyohide
    • Bulletin of the Korean Chemical Society
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    • 제25권3호
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    • pp.377-381
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    • 2004
  • Chiral separation of aryalcohols such as 1-phenyl-propanol, 1-phenyl-2-proanol, and 2-phenyl-1-propanol by capillary electrophoresis has been optimized using the overlapping resolution mapping (ORM) scheme. Three critical parameters of the electrophoretic media, i.e. phosphate concentration, sulfated ${\beta}$-cyclodextrin (CD) concentration and pH, were chosen for optimization. The working ranges were initially presumed by 7 preexperiments. Further optimization was carried out by another seven experiments within the narrow working ranges. From the final overlapping resolution mapping all peak pairs, the area of maximum separations were located. Using the conditions of a point in this area, we found that the target compounds were a baseline separated within 30 min. The maximum separation conditions of arylalcohols were a chiral selector concentration of 5.4%, a phosphate concentration of 28 mM, and a pH of 5.0.

One Idea on a Three Dimensional Measuring System Using Light Intensity Modulation

  • Fujimoto Ikumatsu;Cho In-Ho;Pak Jeong-Hyeon;Pyoun Young-Sik
    • International Journal of Control, Automation, and Systems
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    • 제3권1호
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    • pp.130-136
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    • 2005
  • A new optical digitizing system for determining the position of a cursor in three dimensions(3D) and an experimental device for its measurement are presented. A semi-passive system using light intensity modulation, a technology that is well known in radar ranging, is employed in order to overcome precision limitations imposed by background light. This system consists of a charge-coupled device camera placed before a rotating mirror and a light-emitting diode whose intensity is modulated. Using a Fresnel pattern for light modulation, it is verified that a substantial improvement of the signal to noise ratio is realized for the background noise and that a resolution of less than a single pixel can be achieved. This opens the doorway to the realization of high precision 3D digitized measurement. We further propose that a 3D position measurement with a monocular optical system can be realized by a numerical experiment if a linear-period modulated waveform is adopted as the light-modulating one.

Study of acupuncture stimulation on experimental osteopenia

  • Kanai, Shigeyuki;Taniguchi, Norimasa;Kanda, Kayo;Higashino, Hideaki
    • Advances in Traditional Medicine
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    • 제6권2호
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    • pp.79-85
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    • 2006
  • In order to study the effect of acupuncture stimulation on bone mineral density (BMD), using the ovariectomized (OVX) rat model, we assessed the degree of osteopenia by dual-energy X-ray absorptiometry, measured the level of locomotor activity using a metabolism measuring system, and performed histological studies of bone tissue. Twenty-four female Wistar rats (8 weeks old, 160 - 180 g)were divided into three groups. Rats in the OVX-A group underwent ovariectomy followed by acupuncture stimulation. The OVX rats in the Vehicle control group were not treated with acupuncture as a control. The rats in the control group received neither ovariectomy nor acupuncture. Acupuncture stimulation for 12 weeks in the OVX-A group inhibited the reduction in BMD of the femoral bones caused by ovariectomy. Moreover, in the two OVX groups, there was no clear difference in the level of locomotor activity between the active and resting phases prior to acupuncture stimulation in each rat, and the pattern of locomotor activity was irregular. After acupuncture stimulation of the OVX-A rats, the pattern of locomotor activity became diphasic with clear active and resting phases, as was observed in the Control group. On histological studies, the continuity of trabecular bone was maintained more favorably and bone mass was higher in the OVX-A group than in the vehicle control group. These results suggest that the increased locomotor activity that had been induced by acupuncture stimulation increased the BMD.

Preparation of Three Different Style Packed Capillary Frits

  • Ryoo, Jae-Jeong;Song, Young-Ae;Lee, Kwang-Pill;Park, Ji-Yeon;Choi, Seong-Ho;Hyun, Myung-Ho;Ohta, Kazutoku;Fujimoto, Chuzo;Jin, Ji-Ye;Takeuchi, Toyohide;Lee, Jung-Whan
    • Bulletin of the Korean Chemical Society
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    • 제27권4호
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    • pp.524-528
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    • 2006
  • Three different style capillary columns, a packed capillary with temporary quartz wool frit, a packed capillary with immobilized frit, and an immobilized packed-capillary, were easily prepared with a commercially available (S)-N-(3,5-dinitro-benzoyl)leucine-N-phenyl-N-alkylamide derived chiral stationary phase. Liquid chromatographic chiral separations of some racemic amino acid derivatives on these columns were performed and the results were compared to each other. The packed capillary with immobilized frit showed some merits in chiral chromatography.

Research of reducing thermal stress generated in MGC turbine nozzles

  • Fujimoto, Syuu
    • 한국추진공학회:학술대회논문집
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    • 한국추진공학회 2004년도 제22회 춘계학술대회논문집
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    • pp.385-390
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    • 2004
  • An unique ceramic material produced through unidirectional solidification with eutectic composition of two-phase oxides was introduced recently. This composite material has the microstructure of coupled networks of two single crystals interpenetrate each other without grain boundaries. Depending on this microstructure this material, called Melt Growth Composite (MGC), can sustain its room temperature strength up to 1$700^{\circ}C$ (near its melting point) and offer strong oxidization-resistant ability, making its characteristics quite ideal for the gas turbine application. The research project on MGC started in 2001 with the objective of establishing component technologies for MGC application to the high temperature components of the gas turbine engine. MGC turbine nozzles are expected to improve efficiency of gas turbine. However, reduction of the thermal stress is required since high thermal stress is easily generated in MGC turbine nozzles due to temperature distribution. Firstly, the hollow nozzle shape was optimized to reduce thermal stress using numerical analysis. From the results of the first hot gas flow tests, the thermal stress due to span-wise temperature distribution was required to be reduced, and separated nozzle to three pieces was designed. This was tested in hot gas flow at 140$0^{\circ}C$ level, and temperature distributions on the nozzle surface were obtained and stress field was evaluated.

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다성분 혼합연료를 이용한 디젤 분무 및 연소특성의 광계측 진단 (Laser Diagnostics of Spray and Combustion Characteristics Using Multi-Component Mixed Fuels in a D.I. Diesel Engine)

  • 윤준규;명광재;천전이랑;등본원;차경옥
    • 한국자동차공학회논문집
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    • 제14권5호
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    • pp.172-180
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    • 2006
  • This study was to analyze the effect of mixed fuel composition and mass fraction on the characteristics of evaporating diesel spray and combustion under the various ambient conditions. The characteristics of vaporization distribution and combustion were visualized by laser induced fluorescent method and direct photography. The experiments were conducted in the constant volume vessel and rapid compression expansion machine with optical access. Multi-component fuels mixed i-octane, n-dodecane and n-hexadecane were injected the vessel and rapid compression expansion machine with electronically controlled common rail injector. Experimental results show that fuel vapor formed stratified distribution. And vaporization and diffusion are become actively increasing in mass fraction of low boiling point component. Consequently multi-component fuels were expected to control the evaporating behavior according to their suitable mass fraction.

Lateral Stability Control of Electric Vehicle Based On Disturbance Accommodating Kalman Filter using the Integration of Single Antenna GPS Receiver and Yaw Rate Sensor

  • Nguyen, Binh-Minh;Wang, Yafei;Fujimoto, Hiroshi;Hori, Yoichi
    • Journal of Electrical Engineering and Technology
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    • 제8권4호
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    • pp.899-910
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    • 2013
  • This paper presents a novel lateral stability control system for electric vehicle based on sideslip angle estimation through Kalman filter using the integration of a single antenna GPS receiver and yaw rate sensor. Using multi-rate measurements including yaw rate and course angle, time-varying parameters disappear from the measurement equation of the proposed Kalman filter. Accurate sideslip angle estimation is achieved by treating the combination of model uncertainties and external disturbances as extended states. Active front steering and direct yaw moment are integrated to manipulate sideslip angle and yaw rate of the vehicle. Instead of decoupling control design method, a new control scheme, "two-input two-output controller", is proposed. The extended states are utilized for disturbance rejection that improves the robustness of lateral stability control system. The effectiveness of the proposed methods is verified by computer simulations and experiments.

간섭계에 있어서의 계통 오차의 자율 교정 알고리즘 (Self-calibration Algorithm of Systematic Errors For Interferometer)

  • 후지모토 이쿠마츠;이태용
    • 한국정밀공학회지
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    • 제22권5호
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    • pp.63-71
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    • 2005
  • When an almost flat surface under test is measured by an interferometer, the measurement result is largely influenced by systematic errors that include geometrical errors of a reference flat surface. To determine the systematic errors of the interferometer by the conventional method that is called the three flat method, we must take the reference flat surface out from the interferometer and measure it. Because of difficulties to set the reference flat surface to the interferometer exactly and quickly, this method is not practical. On the other hand, the method that measures a surface under test with some shifts in the direction being perpendicular to the optical axis of the interferometer is studied. However, the parasitic pitching, rolling and up-down movement caused by the above shifts brings serious error to the measurement result, and the algorithm by which the influences can be eliminated is not still established. In this paper, we propose the self-calibration algorithm for determining the systematic errors that include geometrical errors of a reference flat surface by several rotation shifts and a linear shift of general surface under test, and verify by a numerical experiment that this algorithm is useful for determining the systematic errors.