• Title/Summary/Keyword: Fst

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Multilocus Genotyping to Study Population Structure in Three Buffalo Populations of India

  • Tantia, M.S.;Vijh, R.K.;Mishra, Bina;Kumar, S.T. Bharani;Arora, Reena
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.8
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    • pp.1071-1078
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    • 2006
  • Three buffalo populations viz. Bhadawari, Tarai and local buffaloes of Kerala were genotyped using 24 heterologous polymorphic microsatellite loci. A total of 140 alleles were observed with an average observed heterozygosity of 0.63. All the loci were neutral and 18 out of the 24 loci were in Hardy Weinberg Equilibrium. The $F_{IS}$ values (estimate of inbreeding) for 16 loci in all the three populations were negative. This indicated lack of population structure in the three populations. The effective number of immigrants was 5.88 per generation between the Tarai and Bhadawari populations which was quite high suggesting substantial gene flow. The genetic distances revealed closeness between the Tarai and Bhadawari populations which was expected from geographical contiguity. The FST values were not significantly different from zero showing no population differentiation. The Correspondence Analysis based on the allelic frequency data clustered the majority of the Tarai and Bhadawari individuals as an admixture.

Effects of Lycii Radicis Cortex in HPA-Axis System on the Forced Swimming Test (지골피(地骨皮)가 강제수영부하실험에서 HPA-Axis System에 미치는 영향)

  • Koo, Beom-Mo;Lee, Tae-Hee
    • Herbal Formula Science
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    • v.18 no.2
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    • pp.215-225
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    • 2010
  • In order to investigate the antidepressant effects of Lycii Radicis Cortex on the change of HPA-Axis system, the forced swimming test was performed. The expressions of CRF and c-Fos in the PVN were measured with immunohistochemical method and the concentration of ACTH in Serum was evaluated with ELISA method. And the results obtained were as follows. Results : 1. The duration of immobility in the forced swimming test was significantly decreased in the LRC100 group and the LRC400 group(P<0.001). 2. The expressions of CRF and c-Fos were significantly reduced in the LRC100 group and the LRC400 group(P<0.001). And the concentration of ACTH in Serum were significantly reduced in the LRC 100 group(P<0.05). According to the results above mentioned, it can be considered that Lycii Radicis Cortex has antidepressant effects.

Effect on 400 series Ferrite Stainless Steel Corrosion Resistance of ABS Sensor Ring (400계열 FSTS의 내식성이 ABS 센서 링에 미치는 영향)

  • 양현수
    • Journal of the Korea Safety Management & Science
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    • v.2 no.3
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    • pp.197-210
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    • 2000
  • In this paper, sensor ring for antilock brake system was studied using the 400 series ferrite stainless steel powder. Because of more excellent corrosion resistance and mechanical characteristics than iron, sensor ring has been manufactured by P/M(Powder Metallurgy) method 400 series ferrite stainless steel. the results are following. 1, Compared with sensor ring made by iron, 400 series ferrite stainless steel has shown a good corrosion resistance without an addition surface treatment. thus the decreasing production process has been obtained. 2. The products before sintering are much more corrodible in the condition of spray test of salt water and ammonia than humidity and nitrogen condition.

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Thermal Deformation Analysis of Shadow Mask : Temperature Distribution (쉐도우마스크의 열변형 해석 -온도분포)

  • 김현규;천현태;임세영
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.17 no.10
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    • pp.2574-2581
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    • 1993
  • A Shadow mask in C. R. T. (Cathod Ray Tube) undergoes a temperature increase due to impinging electron beams emitted from guns, and thermal deformation from such temperature rise may cause the electron beams to island on the panel, and thus give rise to depolarization. Hence the analysis of temperature distribution for a shadow mask is an important procedure for designing the shadow mask. In this paper, we are concerned with nonlinear finite element analysis of the temperature distribution on a shadow mask. First of all, we replace shadow mask, containing numerous apertures of a slit type, by an orthotropic shell without apertures, and calculate the apparent thermal conductivities. Because of thermal radiation, which is one of the major heat transfer mechanism for shadow masks, the resulting finite element equation is nonlinear and solved by the Newton method. Finally numerical examples are illustrated for a 21" FST(Full Square Tube) shadow mask, and followed by discussion.sion.

A speed predictive control of the AC servo motor using DSP processor (DSP를 사용한 AC 서보 모터의 속도 예측 제어)

  • 김진환
    • Journal of the Korean Institute of Telematics and Electronics S
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    • v.35S no.7
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    • pp.22-28
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    • 1998
  • This paper includes AC servo motor speed control usig the predictive control strategy. Generally, AC servo motor control should have the fast response characteristics. For the issue, sliding mode control and PID control have been applied. However, the former has the speed ripple response due to the chattering and the latter requires the many trial efforts. Originally, the predictive control which has been used in process control area does not need the priori knowledge for the application system and it is easy to compute the optimal gain with the prediction. In this paper, the TMS320C31 DSP pocessor is used for AC motor control with fst dynamics and the tuning guid-line for the parameters of the predictive control algorithm is given in order to reduce the computation load. Also, the actuator saturationis implemented uisngthe QP(Quadratic Programming) method and the transient response is improved by the identified intertia coefficient when AC motor is drived at forward/reverse rotation.

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A Fuzzy Spatiotemporal Data Model and Dynamic Query Operations

  • Nhan, Vu Thi Hong;Kim, Sang-Ho;Ryu, Keun-Ho
    • Proceedings of the KSRS Conference
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    • 2003.11a
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    • pp.564-566
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    • 2003
  • There are no immutable phenomena in reality. A lot of applications are dealing with data characterized by spatial and temporal and/or uncertain features. Currently, there has no any data model accommodating enough those three elements of spatial objects to directly use in application systems. For such reasons, we introduce a fuzzy spatio -temporal data model (FSTDM) and a method of integrating temporal and fuzzy spatial operators in a unified manner to create fuzzy spatio -temporal (FST) operators. With these operators, complex query expression will become concise. Our research is feasible to apply to the management systems and query processor of natural resource data, weather information, graphic information, and so on.

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Analysis of Microsatellite Loci for Swimming Crab Portunus trituberculatus Populations in the Korean Side of the Yellow Sea (서해안에서 채집된 꽃게(Portunus trituberculatus) 집단에 대한 microsatellite 좌위의 분석)

  • Lee, Hye Jin;Yoon, Seong Jong;Hyun, Young Se;Kim, Hye Jin;Hwang, Sung-Il;Bae, Joo-Seung;Chung, Ki Wha
    • Journal of Life Science
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    • v.23 no.9
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    • pp.1088-1095
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    • 2013
  • The swimming crab, Portunus trituberculatus, inhabits seafloor habitats containing sand or pebbles and is widely distributed throughout the world. The present study investigated genetic polymorphisms of 10 microsatellites in 281 samples of P. trituberculatus collected from four locations along the coastal water of the Korean side of the Yellow Sea (Yeonggwang, Taean, Sorea, and Yeonpyeong-do Island). The number of alleles per locus ranged from 50 to 129, with a mean of 69.5. The observed and expected hetrozygosity varied from 0.111 to 1.000 and from 0.609 to 0.979, respectively. The inbreeding coefficients (Fis) varied among the loci from -0.0207 to 0.8175. The genetic differentiation (Fst) was less than 0.05 (range 0.0020-0.0124). Therefore, the four groups of P. trituberculatus appeared to exhibit little genetic differentiation. The lack of differentiation was confirmed in a phylogenetic tree constructed by the unweighted pair group method with the arithmetic average (UPGMA). The hypervariation between the populations and the lack of genetic differentiation may reflect active gene flow among the Yellow Sea populations and the absence of geographical boundaries. The highly polymorphic microsatellite loci will be useful for molecular and phylogenetic studies, as well as stock management, of swimming crab, which is an important fishery resource.

Genetic Features of Cheju Horses based on Transferrin Gene Frequency (Transferrin 유전자빈도에 의한 제주마의 유전적 특성)

  • Yang, Y.H.;Kim, N.Y.
    • Journal of Animal Science and Technology
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    • v.46 no.1
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    • pp.15-22
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    • 2004
  • To investigate genetic features and the allele distribution of transferrin gene in three Cheju horse groups (group I, 137 horses of Jeju institute; group II, 107 horses of farms; group III, 89 racing horses) and three foreign breeds(l03 Thoroughbred, 10 Mongolian and 5 American Quarter horses), transferrin gene exons 13, 15, and 16 were analyzed by SSCP. The allele frequencies of transferrin gene of these groups and breeds were used to calculate genetic distances and to test population differentiations. The Fst values were 0.067 between Cheju horse groups I and II, 0.070 between Cheju horse groups I and group III, 0.091 between Cheju horse group I and Mongolian breed, and 0.189 between Cheju horse group I and Thoroughbred breed. Cheju horse group I showed significant population differentiation from other two Cheju horse groups and three foreign breeds while Cheju horse group III showed significant population differentiation only from Cheju horse group I and Thoroughbred breed(p <0.05). Results indicate that three Cheju horse groups showed population differentiation between each other, suggesting genetic heterogeneity of Cheju horses.

Study on the Anti-Fatigue and Immune-Enhancing Effects of Gami-Yukmi-Jihwang- Tang (가미육미지황탕의 항피노와 면역 증강 효과에 대한 연구)

  • Kim Hyun Hee;Park Eun Jung;Kim Jong Yeol;Joo Jong Cheon
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.6
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    • pp.1762-1768
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    • 2004
  • The Korean formula medicine, Gami-Yukmi-Jihwang-Tang (GYJT) has been used for growing slowly, short of stature, incomplete development, fatigue, weak child, growing pain of child. However, it is still unclear how GYJT has an effect on experimental models. In the present study, the author investigated the immune-enhancing effect of GYJT. Forced swimming test (FST) was performed as a model of activity test in mice and measured blood urea nitrogen (BUN), aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactic dehydrogenase (LDH), glucose (Glc) and total protein (TP) in the serum. GYJT (1, 0.1 and 0.01 g/㎏) were orally administered to mice, once per day for 7 days using a feeding atraumatic needle. After 3 days, on FST, the immobility time was significantly decreased in the GYJT (0.01g/㎏/day)-fed group (120.75±5.71s) in comparison with the saline-fed group (153.80±10.74s). After 7 days, the immobility time was significantly decreased in the GYJT (0.1 and 0.01g/㎏/day)-fed group (125.67±5.36s and 107.67±3.71s) in comparison with the saline-fed group (167.67±12.99s). In addition, the contents of BUN and Glc in the blood serum were significantly decreased and the contents of AST, ALT and LDH were also decreased in the GYJT (1g/㎏/day)-fed group. However, the content of TP was not changed. The present results suggest that GYJT may be useful for the anti-fatigue and immune-enhancing agent. Also, the author investigated the effect of GYJT on the production of cytokines in human T-cell line, MOLT-4 cells. However, GYJT has not affected the production of IFN­γ, IL-2, IL-4. These results suggest that GYJT has immune-enhancing effect but does not affect T cell-mediated production of cytokines in the immune function improvement.

Chronic Administration of Baicalein Decreases Depression-Like Behavior Induced by Repeated Restraint Stress in Rats

  • Lee, Bombi;Sur, Bongjun;Park, Jinhee;Kim, Sung-Hun;Kwon, Sunoh;Yeom, Mijung;Shim, Insop;Lee, Hyejung;Hahm, Dae-Hyun
    • The Korean Journal of Physiology and Pharmacology
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    • v.17 no.5
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    • pp.393-403
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    • 2013
  • Baicalein (BA), a plant-derived active flavonoid present in the root of Scutellaria baicalensis, has been widely used for the treatment of stress-related neuropsychiatric disorders including depression. Previous studies have demonstrated that repeated restraint stress disrupts the activity of the hypothalamic-pituitary-adrenal (HPA) axis, resulting in depression. The behavioral and neurochemical basis of the BA effect on depression remain unclear. The present study used the forced swimming test (FST) and changes in brain neurotransmitter levels to confirm the impact of BA on repeated restraint stress-induced behavioral and neurochemical changes in rats. Male rats received 10, 20, or 40 mg/kg BA (i.p.) 30 min prior to daily exposure to repeated restraint stress (2 h/day) for 14 days. Activation of the HPA axis in response to repeated restraint stress was confirmed by measuring serum corticosterone levels and the expression of corticotrophin-releasing factor in the hypothalamus. Daily BA administration significantly decreased the duration of immobility in the FST, increased sucrose consumption, and restored the stress-related decreases in dopamine concentrations in the hippocampus to near normal levels. BA significantly inhibited the stress-induced decrease in neuronal tyrosine hydroxylase immunoreactivity in the ventral tegmental area and the expression of brain-derived neurotrophic factor (BDNF) mRNA in the hippocampus. Taken together, these findings indicate that administration of BA prior to the repeated restraint stress significantly improves helpless behaviors and depressive symptoms, possibly by preventing the decrease in dopamine and BDNF expression. Thus, BA may be a useful agent for the treatment or alleviation of the complex symptoms associated with depression.