• Title/Summary/Keyword: Frontal base

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Neurochemical Profile Quantification of Regional Adult Mice Brain Using: ex vivo $^1H$ High-Resolution Magic Angle Spinning NMR Spectroscopy (생체 외 조직 고 분해능 Magic Angle Spinning을 이용한 정상 Adult Mice에서의 뇌 부위별 뇌 신경화학 대사물질 정량분석)

  • Lee, Do-Wan;Woo, Dong-Cheol;Lee, Sung-Ho;Kim, Sang-Young;Kim, Goo-Young;Rhim, Hyang-Shuk;Choi, Chi-Bong;Kim, Hwi-Yool;Lee, Chang-Wook;Choe, Bo-Young
    • Progress in Medical Physics
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    • v.21 no.1
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    • pp.35-41
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    • 2010
  • The purpose of this study is to quantitate regional neurochemical profile of regional normal adult mice brain and assess regional metabolic differences by using ex vivo $^1H$ high-resolution magic angle spinning nuclear magnetic resonance spectroscopy ($^1H$ HR-MAS NMRS). The animals were matched in sex and age. The collected brain tissue included frontal cortex, temporal cortex, thalamus, and hippocampus. Quantitative 1D spectra were acquired on 40 samples with the CPMG pulse sequence (8 kHz spectral window, TR/TE = 5500/2.2 ms, NEX = 128, scan time: 17 min 20 sec). The mass of brain tissue and $D_2O$+TSP solvent were 8~14 mg and 7~13 mg. A total of 16 metabolites were quantified as follow: Acet, NAA, NAAG, tCr, Cr, tCho, Cho, GPC + PC, mIns, Lac, GABA, Glu, Gln, Tau and Ala. As a results, Acet, Cho, NAA, NAAG and mIns were showed significantly different aspects on frontal cortex, hippocampus, temporal cortex and thalamus respectively. The present study demonstrated that absolute metabolite concentrations were significantly different among four brain regions of adult mice. Our finding might be helpful to investigate brain metabolism of neuro-disease in animal model.

CAROTID-CAVERNOUS SINUS FISTULA ACCOMPANYING FACIAL BONE FRACTURE : Report of a Case (안면골 골절과 동반된 경동맥해면동루의 증례보고)

  • Park, No-Bu;Seo, Yeon-Ho;Moon, Seon-Hye;Lee, Yong-Oh
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.15 no.2
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    • pp.100-104
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    • 1993
  • Carotid-cavernous sinus fistula(CCSF) is an abnormal arterio-venous communication between the cavernous sinus and the internal carotid artery. It is usually caused by craniofacial trauma and a very rarely encountered complication, but it may also occur spontaneously. The most common cause of traumatic CCSF is blunt trauma, which usually associated with a skull base, frontal or midfacial fracture. The common clinical feature of CCSF are orbital bruit, headache, exophthalmos, chemosis, diplopia, visual disturbance and others. This dramatic ocular-orbital symptoms are principally due to orbital venous hypertension. The symptoms occured within a few hours to a maximum of a year after injury, usually within several weeks. The patient, 33-year-old female, developed a carotid-cavernous sinus fistula after only minimal closed trauma We present a rare case of CCSF associated facial bone fracture that was successfully treated by detachable balloon embolization with a review of the literature.

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A comparative study on the relationship of investing medium to vertical occusal change and surface smoothing during denture processing (Resin processing시(時) 매몰재(埋沒材)에 따른 교합고경(咬合高涇) 및 의치표면(義齒表面) 활택도(滑澤度)의 변화(變化)에 관(關)한 연구(硏究))

  • Kim, Uoong-Chul;Chung, In-Sung
    • Journal of Technologic Dentistry
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    • v.3 no.1
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    • pp.9-16
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    • 1981
  • A comparative study was conducted to evaluate the relationship of investing medium to the amount of vertical occlusal changes and to the differences of surface smoothness during denture construction. Three groups of 20 dentures, 30 sets of upper and lower were fabricated of conventional heatcuring acrylic denture base resin, using silicone-gypsum molding techniques, with or without covering the occlusal surfaces of the teeth by artificial stone and all-gypsum molding techniques. The distance between the two reference points indented by 1/2 round bur on the upper and lower frontal surfaces of each articulator were measured and recorded before processing and again after processing and remounting of each denture on the articulator. The differences between the two recordings indicated the amount of vertical opening during denture processing. The difference of surface smoothness were investigated and determined by 3 observers continual comparing of the two randomly selected dentures with each other, which were seperately selected as pairs from the different two groups of 20. The results obtained were as follows: 1. During resin processing no statistically significant differences of the amount of vertical occlusal changes were detected between any of the two groups of two silicone-gypsum and one allgypsum molding techniques, although the amount of vertical opening was somewhat increased when silicone-gypsum molding technique was used. 2. Surface smoothness of the processed denture was makedly by increased when silicone-gypsum molding technique was used.

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An Analysis of Landscape Change Factors on Restoration Project of Ecological Ridgeline using Landscape Adjectives -Focused on Frontal View- (경관형용사를 활용한 생태축 복원사업의 경관변화요인 분석 - 정면경관을 대상으로-)

  • Lee, Woo-Sung;Park, Yeong Dae;Kwon, Tae-Ho
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.20 no.1
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    • pp.97-115
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    • 2017
  • The purpose of this study is to evaluate the preference and image on landscape of before and after the restoration in the four study areas where the restoration project of Baekdudaegan ecological ridgeline was carried out and to explore the change factors of image preference according to restoration project. The study areas were Beoljae, Ihwaryeong, Bijoryeong, and Yuksimnyeong and 248 questionnaires were used for analysis. As a result of the recognition analysis on restoration project of ecological ridgeline, the awareness of the project was low at 2.63, the satisfaction of the project was 3.42, and necessity of the project was 4.07. In terms of the preference analysis for landscape photographs, the all preferences of four sites were improved after the project than before. In the result of the landscape image evaluation, images such as 'lifeless', 'uniform' and 'ugly' were high before the project, however, images such as 'clean', 'tidy', and 'stable' were high after the project. As a result of analyzing the change factors of image preference according to the restoration project, adjectives such as 'beautiful-ugly' and 'open-closed' influenced the preference change in common. These findings can be utilized as the base data for the planning direction for the construction of new ecological ridgeline or the landscape conservation of existing ecological ridgeline.

OSTECTOMIES FOR MANDIBULAR ANGLE REDUCTION: A SYSTEMATIC REVIEW AND A REPORT OF CASES (하악 우각부 축소를 위한 골절제술의 체계적 고찰 및 증례 보고)

  • Park, Jun-Woo;Choi, Jin-Young;Kim, Hyung-Wook;Kim, Jong-Sik;Choung, In-Won;Kang, Jin-Han;Hong, Soon-Min
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.29 no.4
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    • pp.340-352
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    • 2007
  • In this systematic review on bone reduction procedures for the correction of the prominent mandibular angle, we collected and sorted the methods. The strength and weakness, indication, complication, and final esthetic result of each method were evaluated. After searching and filtering the literatures on the base of inclusion criteria, 9 eligible case series studies were included in this study. There were 3 types of curved ostectomies and 4 types of lateral cortical ostectomies. Surgical procedures for curved ostectomies were divided into 2 types. One was single curved ostectomy and the other was multistaged curved ostectomy. Lateral cortical ostectomies reported were all similar to sagittal split ramus osteotomy. The complications reported in the included studies were scarce, but curved ostectomies may be able to induce many complications. The prominent mandibular angle must be analyzed in the lateral dimension and frontal dimension, and curved ostectomy can reduce the mandibular angle laterally while lateral cortical ostectomy can reduce the bigonial distance frontally. Because curved ostectomies can induce complications and unnaturally large mandibular angle while can not reduce bigonial distance efficiently, the current trend for the angle reduction procedure is lateral cortical ostectomies.

Cerebral activation related with morphological priming effect in production of Korean Endings (한국어 어말어미 산출관련 대뇌 활성화)

  • Hwang, Yu-Mi;Shin, Jung-Moo;Lim, Soo-Mee;Ryu, Keun-Taek;Khang, Hyun-Soo;Yi, Kwang-Oh;Nam, Ki-Chun
    • Proceedings of the Korean Society for Cognitive Science Conference
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    • 2005.05a
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    • pp.273-277
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    • 2005
  • 본 연구는 한국어 어말어미 산출시 나타나는 대뇌 활성화 영역을 살펴보기 위하여 실시되었다. 두 가지 실험이 실시되었다 실험 1은 어말어미의 기본형을 주고 이를 의문형, 명령형으로 산출하는 고립단어 실험을 실시하였다. 통제 조건으로 모음변환조건(C1)과 아라비아문자보기(C2)를 사용하였다. 실험 1의 결과 ‘어말어미-C1’ 조건에서 좌반구의 측두엽과 전두엽부분의 의 활성화 superior temporal gyrus와 inferior frontal gyrus의 활성화가 관찰되었다. ‘어말어미-C2’ 의 조건에서 우반구에서 후두엽의 활성화와 좌반구에서의 후두엽, 전두엽, lingual G, Cuneus, fusiform G, inferior occipital G에서의 활성화를 관찰할 수 있었다. 실험 2는 명령형과 의문형 어미의 형태점화효과와 관련된 대뇌 활성화 영역을 관찰하기 위하여 Er-fMRI 기법을 이용하여 실시되었다. 실험 조건은 어미동일조건, 어간반복조건, 무관련 조건으로 구성되었다. 피험자들은 점화자극이 제시된 후 신호가 제시되고 나오는 표적단어를 의문형 또는 명령으로 산출하도록 하는 과제를 실시하였다. 뇌 활성화 영역을 분석한 결과 의문형과 명령형을 산출할 때의 활성화 영역에서 $^{\ast}^{\ast}^{\ast}$를 볼 때의 영역을 빼기 (substraction)한 결과 공통적으로 좌반구 브로카 영역이 활성화되었고, 의문형과 명령형 안에서 어미동일조건에서 무관련 조건을 뺀 경우에는 좌반구의 superior temporal G 영역의 활성화가 관찰되었다. 이들 결과를 종합해 볼 때 어말어미 산출 그 자체와 직접 관련되는 영역으로는 좌반구의 측두엽과 전두엽 부분이 관찰되었다. 특히 한국어 어말어미 산출시 나타나는 형태점화 양상과 관련된 대뇌영역으로 발견된 브로카 영역에서의 활성화는 어미 변환과 관련된 영역이라기보다는 산출시 관련되는 articulation, motor coordinate관련 영역으로 추정되고, 측두엽의 활성화는 형태소, 의미 관련 지식의 data base로 추정된다. 또한 우반구 전두엽 부분에서 관찰된 활성화는 억제관련 영역으로 짐작된다.

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Effects of Extranasal Molding after Primary Cleft Lip Nasal Repair: Photogrammetric Analysis (구순열비교정술 후 외비주형술(Extranasal molding): 비주길이의 사진계측학적 분석)

  • Han, Ki Hwan;Paik, Dae Hyang;Son, Hyung Bin;Kim, Jun Hyung;Son, Dae Gu
    • Archives of Plastic Surgery
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    • v.33 no.5
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    • pp.563-569
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    • 2006
  • Purpose: In the correction of cleft lip, there have been various methods to minimize recurrence of the nasal deformity after primary nasal surgery. After cheiloplasty and primary nasal surgery, we tried to elongate the columella of the cleft side, to stretch the vestibular lining of cleft side, and to elevate the alar cartilage of the cleft side with a molding prong. Methods: We had fifteen cleft lip patients; 12 unilateral cases(6.3-8.2 months), and 3 bilateral cases(3 - 7.5 months). Immediately after primary repair of the cleft lip, the toboggan shaped molding prong was located to deep inside of vestibular web of the cleft side. It was persistently suspended by a silicone tube which was connected to the prong and the frontal scalp. The results were analyzed with $Photoshop^{(R)}$ photogrammetrically for 6 - 48 months with on average of 20.6 months. We measured the proportion index of columellar length-interalar distance for three times(preoperation, immediate postoperation, and postoperation) on the nasal base views. Results: In unilateral, the index had a significant increase statistically between preoperation(10.73) and immediate postoperation(23.96). It is supposed that columellar length was reconstructed to 105.80% of normal side. But, it was decreased to maintain 87.7% of normal side in postoperation(20.54). The results were similar in bilateral. The linear scars by suture penetrating nose skin were not discernable. Conclusion: In summary, placement of the molding prong could elongate the reconstructed columella with some relapse postoperatively.

MAXILLOFACIAL ESTHETICS BY THREE DIMENSIONAL FACIAL MORPHOMETRICS (삼차원적 안모형태의 미적분석)

  • Lee, Sang-Han;Kwon, Tae-Geon;Baek, Sang-Heum
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.26 no.6
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    • pp.606-612
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    • 2000
  • This study was performed to investigate the average anthropometric value of normal Korean men and women and to compare the preceding literatures. Additionally, average Korean profilogram was made to serve as a template for diagnosis of facial form. Eighty five Korean subjects(41 men, 44 women) aged between 21 to 26 were selected by members of the author's department on the basis of intact dentition and Class I occlusion without facial asymmetry. Frontal and lateral photographs were taken under standardized condition with digital camera. The image was magnified and adjusted according to the FH plane of cephalometric radiographs and digitized using personal computer. To compare the Western beauty, 25 esthetically pleasing female was selected to measure various angle and distance of the face. 1. It was possible to calculate the mean coordinate value of Korean normal samples which enables the direct visualization and comparison with the use of template. The method in this study was easy to applicate under the Microsoft $Windows^{(R)}$ bases. 2. Maxillary vertical hypoplasia, upper and lower lip protrusion was characteristics of Korean norms and relatively narrow alar base distance, less conspicuous nasal projection was observed. As the vermilion exposure and upper lip length was more than western norm, chin looks shorter than western. To compare the Korean and Western esthetically pleasing profile, facial convexity and nose was less conspicuous in Korean women.

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A STUDY OF THE SUTURAL FACIAL BONE GROWTH OF RABBIT : SERIAL ROENTGENOGRAPHIC STUDY BY MEANS OF MEANS OF IMPLANTS (금속매식법(金屬埋植法)에 의(依)한 가토(家兎)의 봉합성(縫合性) 안면골성장(顔面骨成長)에 관(關)한 X-선학적(線學的) 연구(硏究))

  • Lee, Won Chul
    • The korean journal of orthodontics
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    • v.9 no.1
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    • pp.23-35
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    • 1979
  • The present study has the purpose of investigating various growth and developmental aspects of rabbit snout with the aid of metallic implantation and of improving on the indirect method of growth and developmental studies of its skull. Sixty-eight growing albino rabbits were used. A head holder, film holder, cephalometer, metallic implanting device and implant materials were designed and constructed by the author. Eight metallic pins were implanted with a metallic implanting device in the rabbit snout under general anesthesia. Two metallic pins were implanted on each side of the interfrontal suture and another two were put on each side of the internasal suture near the frontonasal suture. Serial cephalograms were taken with a two-week interval, using the head holder, film holder and cephalometer. Eight items of linear measurement were obtained from the film. On the base of the results of the study, the following conclusions are obtained: 1. The metallic implant method is better than the other indirect methods for growth and developmental studies of the rabbit skull. 2. Most of the vertical growth of the rabbit snout is due to sutural growth at the frontonasal suture and the horizontal growth is at the interfrontal and the internasal suture. 3. The vertical growth of the rabbit snout is greater than the horizontal growth. 4. The horizontal growth of the rabbit snout is greater at the nasal bone than at the frontal bone. 5. The amount of vertical growth of the rabbit snout is almost same at inner and outer side of the interfrontal and internasal suture line, 6. Growth rate of the sutural growth of the rabbit snout tends to decrease by the growth of the rabbit. 7. Implant materials do not disturb growth and development of the rabbit snout, except a slight trauma effect during the first week of metallic implantation.

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COARSE GRID LARGE-EDDY SIMULATION OF FLOW OVER A HEAVY VEHICLE (화물차 주위 유동의 성긴 격자 큰에디모사)

  • Lee, S.;Kim, M.;You, D.;Kim, J.J.;Lee, S.J.
    • Journal of computational fluids engineering
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    • v.21 no.1
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    • pp.30-35
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    • 2016
  • In order to investigate effects of grid resolution on large-eddy simulation of flow over a heavy vehicle, large-eddy simulations over the vehicle with coarse grid and fine grid are conducted. In addition, comparison of drag coefficients with the experimental data obtained by a wind tunnel experiment is conducted. Both of the drag coefficients of coarse grid and fine grid large-eddy simulation show good agreement with the experimental data. Flow fields obtained by the coarse and the fine grid large-eddy simulation are compared in the vehicle frontal-face region, the vehicle rear wheel region, and the vehicle base region. Coarse grid large-eddy simulation shows good agreement with the fine grid large-eddy simulation in the vehicle front face region and the vehicle rear wheel region, since the flow over the present vehicle is dominated by flow separation which is geometrically pre-determined, not by the skin friction which is known to be sensitive to grid resolution.