• Journal of Acupuncture Research
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• v.19 no.4
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• pp.167-182
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• 2002

This experiment was designed to investigate the effects of electroacupuncture (EA) on chronic pains and factors that affected EA effects. The responses of wide dynamic range (WDR) cells to electrical stimulation of $A{\delta}$ & C afferent fibers were used as an index of pain in rats with chronic pains induced by intraplantar injection of complete Freund's adjuvant or peripheral nerve injury. In rats with chronic pains, low (2Hz) and high (100Hz) frequency EA stimulation applied to zusanli caused the inhibition of WDR cell responses in about 60% of rats and the inhibitory actions were dependent on the stimulus strength. EA stimulation also induced an excitation of WDR cell responses in 23.9% of rats and no effect in 15.8% of rats. However, it seemed that in normal rats compared to the rat with chronic pains, the incidence of which EA stimulation caused the excitation or no effect was high. Reversible spinalization almost completely blocked EA-induced inhibitory or excitatory effects. EA stimulation more frequently induced the excitation of WDR cell responses in lightly anesthetized (0.6%) rats and the enhanced responses of WDR cells were inhibited by EA stimulation in the rat anesthetized with 1.5% enflurane. These experimental findings suggest that in rats with chronic pain, EA stimulation inhibited WDR cell responses to slow $A{\delta}$ and C fiber stimulation and EA-induced inhibitory action was under the control of descending inhibitory system and degree of anesthesia.

• Transactions of the Korean Society of Automotive Engineers
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• v.3 no.1
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• pp.1-12
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• 1995

Isothermal and thermal-mechanical fatigue characteristics of 12Cr heat resisting steel used for high temperature applications were investigated including hold time effects. Isothermal low cycle fatigue test at $600^{\circ}C$ and in-phase, out-of-phase thermal-mechanical fatigue test at 350 to $600^{\circ}C$ were conducted using smooth cylindrical hollow specimen under strain-control with total strain ranges from 0.006 to 0.015. Regardless of thermal-mechanical and isothermal fatigue tests, cyclic softening behavior was observed and much more pronounced in the thermal-mechanical fatigue tests with hold times due to the stress relaxation during the hold time. The phase difference between temperature and strain in thermal-mechanical fatigue tests resulted in significantly shorter fatigue life for out-of-phase compared to in-phase. The differences in fatigue lives were dependent upon the magnitudes of plastic strain ranges and mean stresses. During the hold time in the strain-controlled fatigue tests, the increase in the plastic strain range and the stress relaxation were observed. It appeared that the increase in plastic strain range per cycle and the introduction of creep damage made important contributions to the reduction of thermal-mechanical fatigue life with hold time, and the life reduction tendency was more remarkable in the in-phase than in the out-of-phase thermal-mechanical fatigue. Isothermal fatigue tests performed under the combination of fast and slow strain rates at $600^{\circ}C$ showed that the fatigue life decreased as the strain rate and frequency decreased,especially for the low strain ranges.

• Korean Journal of Biological Psychiatry
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• v.15 no.3
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• pp.186-193
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• 2008

Objectives : The authors tried to investigate the characteristics of Heart Rate Variability(HRV) among the subjects with metabolic syndrome for testing the possibility of clinical application of HRV in evaluating metabolic syndrome. Methods : We examined the difference of the means of HRV between 122 subjects of metabolic syndrome and 1057 healthy controls using T-test, and the change of means in HRV according to increasing risk factors of metabolic syndrome. Using multiple regression analysis, we examined the association of HRV with the risk factors of metabolic syndrome. Results : The HRV indices including SDNN(Standard Deviation of all normal NN intervals), RMSSD(the square Root of the Mean Squared Differences of successive all normal NN interval), TP(Total Power), LF(Low Freuency), and HF(High Frequency) were significantly lower in the metabolic syndrome group than in the normal control group, and the means of all HRV indices except LF/HF were decreased consistently according to increasing risk factors of metabolic syndrome. The fasting glucose, triglyceride, and waist circumference were dependent factors that contributed significantly to the change of HRV. Conclusion : These findings suggest metabolic syndrome adversely affects cardiac autonomic system and HRV could be a useful method for evaluating metabolic syndrome.

• Journal of the Korean Society of Visualization
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• v.14 no.1
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• pp.57-61
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• 2016

We report a finding of fast(exceeding 2,000 K/s) heating of polydimethylsiloxane(PDMS), one of the most commonly-used microchannel materials, under cyclic loadings at high(~MHz) frequencies. A microheater was created based on the finding. The heating mechanism utilized vibration damping of sound waves, which were generated and precisely manipulated using a conventional surface acoustic wave(SAW) microfluidic system, in PDMS. The penetration depths were measured to range from $210{\mu}m$ to $1290{\mu}m$, enough to cover most microchannel heights in microfluidic systems. The energy conversion efficiency was SAW frequency-dependent and measured to be the highest at around 30 MHz. Independent actuation of each interdigital transducer(IDT) enabled independent manipulation of SAWs, permitting spatiotemporal control of temperature on the microchip. All the advantages of this microheater facilitated a two-step continuous flow polymerase chain reaction(CFPCR) to achieve the billion-fold amplification of a 134 bp DNA amplicon in less than 3 min. In addition, a technique was developed for establishing dynamic free-form temperature gradients(TGs) in PDMS as well as in gases in contact with the PDMS.

• Proceedings of the Korean Society for Applied Microbiology Conference
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• 2000.04a
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• pp.178-181
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• 2000

In order to develop the novel gene expression system, we introduced new control elements which could influence the foreign gene expression in animal cells. When the foreign genes are introduced into the genome of higher eukaryotic cells, the expressions from these integrated genes are often low and can vary greatly depending on the positions of the integration sites due to the complex nature of the chromatin structures (1). First we screened the various DNA sequence elements which can function as an insulator of gene expression from these position effects and can cooperate with the SV40 enhancer/promoter. Among the several DNA elements from the various sources, we identified the particular DNA element which confers the increased frequency of the positive colonies, assayed by the reporter gene from stable selections indicating significantly reduced position effects. This element also showed the several fold-increased expression level as well as the copy-number dependent expression with host cell specificity. Second we modified the transcription termination element where we introduced the specific terminator in combination with SV40 polyA signal. This modified terminator showed the increased efficiency and the level of the gene expression. By combining these two elements, we made the animal cell expression system and tested successfully for the recombinant protein productions of TGF ${\beta}$-soluble receptor, Antithrombin III, and single chain Pro-Urokinase. [Supported by grants from MOCIE]

• Journal of the Society of Naval Architects of Korea
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• v.36 no.1
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• pp.90-98
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• 1999

For the control of vibration and noise of metal structures having relatively low damping, viscoelastic materials are widely used and usually attached at metal structures with an additional constraining layer to secure them. The damping and elastic properties of structures having constrained viscoelastic material layers are dependent on not only temperature and frequency but also their thicknesses. Hence, optimal design of the thicknesses of viscoelastic and constraining layers for a certain base structure are very important to maximize their efficiency and to lighten their weight. In this study, the variation of loss factor of beams having a constrained viscoelastic layer according to the change of thickness has been carefully investigated. From these, optimal design method of the minimum thickness beam having a given loss factor is suggested and numerically verified for a real beam.

• Journal of Korean society of Dental Hygiene
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• v.7 no.1
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• pp.61-72
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• 2007

The purposes of this study were to investigate the oral health status of the disabled children attending special schools in Seoul and Gyeonggi area, which were to collect baseline data for set up a oral health center in special schools. The study group comprised 915 disabled children aged 12~15 year. They were examined clinically and surveyed on 4 oral health related characteristics according to the type and level of disabilities The results may be summarized as follows: 1. DMFT index was the highest in children with crippled disorder. The plaque control was more required to the children with mental retardation or developmental disorder other than another types of disabilities. 2. About one third of the children with mental retardation or developmental disorder had their teeth brushed at least 3 times daily without any help. Over the half of the children with crippled disorder had their teeth brushed 2 times daily, 33.3% were independent and 38.9% totally dependent on help from others. 3. The more level of disabilities was higher, the more frequency of tooth brushing was lower and degree of dependance of the tooth brushing was higher. 4. There was tendency to visit to dental office more frequently for relief of dental symptoms in children with crippled disorder 5. The inability to call for help from others was the major barrier to dental care for the disabled.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.10B
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• pp.866-879
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• 2004

This paper presents a pricing model for maximizing a service provider's profit, taking into account consumers' quality-of-service dependent willingness to pay, in integrated voice/data mobile services. For the voice and the data services, time-sensitive pricing and volume-sensitive pricing mechanism will be applied, respectively, as in the case of Korea's mobile service market. Assuming that consumers are very sensitive to call interruption during handoff moments, the model presented here considers reserving guard channels exclusively for handoff traffic, in the process of frequency channels allocation, as well as guaranteeing consumers quality of service regarding call interruption rate. Ultimately, this model proposes a means to guarantee the quality of service in the short term, through pricing strategies as well as channel allocation policies, and the simulation results show that without expanding system resources, there exists a trade-off between profit and quality-of-service guarantee.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.33 no.2
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• pp.54-59
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• 2005

Nonlinear aeroelastic analyses of a missile control fin are performed considering backlash and dynamic stiffness of actuator. Doublet-Hybrid method is used for the calculation of subsonic unsteady aerodynamic forces, and aerodynamic forces are approximated by the minimum-state approximation. For nonlinear flutter analysis backlash is represented by a free-play and is linearized by using the describing function method. Also, dynamic stiffness is function of frequency and is calculated by solving equation of motion for actuator. The linear and nonlinear flutter analyses show that the aeroelastic characteristics are significantly dependent on the backlash and dynamic stiffness. From the nonlinear flutter analysis, various types of limit cycle oscillations are observed in a range of air speeds below the linear divergent flutter boundary. The nonlinear flutter characteristics and the nonlinear aeroelastic responses are also investigated in the time domain.

• Journal of The Korean Society of Integrative Medicine
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• v.4 no.2
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• pp.109-120
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• 2016

Purpose : This study surveyed the relationship between the dietetic behaviors of high school students and nutrition information available from mass media thereby suggesting the way of improving the dietetic health promotion of adolescents. Method : This study surveyed coeducational high school students in S region. 220 questionnaires have been collected and analyzed, which is statistically significant as in other previous studies. The survey lasted for one month, March 14 through April 14 in 2016. The statistical analysis was performed by using the windows version 21.0 of SPSS. Primarily, the frequency analysis and descriptive statistics was carried out on the general information, the usage and confidence of mass media, and the diabetic behaviors of respondents. t-Test and One-way ANOVA were adopted to clarity the mass media usage and diabetic behaviors of respondents for general characteristics. Result : The statistical analysis on the diet usage of mass media among high school students shows that famous restaurants(Response rate 51%) and diet control(20%) are highly evaluated, but disease prevention(15%) is low. Regarding the dietetic information acquisition, the mass media including TV, radio, and Internet appear as main information carriages (p<.001). The confidence in mass media are analyzed in the relation with 10 dietetic behaviors, and 4 items(meal amount: p<.011, vegetable intake: p<.005, protein intake: p<.003) are inversely related to the mass media, which means regular intake party is less dependent of the exterior information. The seaweed(p<.017) intake is statistically significant in confidence level. Conclusion : To increase the interest and the health promotion of students, the dietetic information need to be offered in mass media and education course.