• Journal of Yeungnam Medical Science
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• v.3 no.1
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• pp.301-306
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• 1986

Primary pericardial mesothelioma is a rare tumor of mesodermal origin that is infrequently diagnosed antemortem and survival is short. A 60 year old male case of pericardial mesothelioma(epitheloid type) is reported. He was admitted to Yeungnam University Hospital because of chest pain, dyspnea, orthopnea and nonproductive cough. Chest x-ray suggested pericardial effusion, 2-D echocardiography showed echo free spaces of massive pericardial effusion and areas of thick hyperrefractile echoes arising from the pericardium. Pericardiocentesis was attempted and aspirated fluid was bloody exudate. Pericardial window operation with biopsy was done. Swan-Ganz catheterization showed equalization between right atrial pressure and pulmonary capillary wedge pressure. The pathologic diagnosis was established by histologic finding at pericardial biopsy.

• Clinical and Experimental Reproductive Medicine
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• v.45 no.2
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• pp.88-93
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• 2018

Objective: The aim of this study was to measure reactive oxygen species (ROS) production and total antioxidant capacity (TAC) in the seminal fluid of the male partners in couples undergoing intrauterine insemination and to evaluate correlations between these values and their semen parameters. Methods: The study was conducted at Vamsam Fertility Center, Coimbatore, India and enrolled 110 male patients from whom semen samples were collected. ROS production was measured by a thiobarbituric acid reactive species assay, and TAC was measured by a 2,2-diphenyl-2-picrylhydrazyl free radical assay. The differences in the TAC and malondialdehyde (MDA) levels between the subfertile and fertile groups were analysed. Correlations between sperm parameters and TAC and MDA levels were statistically analysed, and cutoff values with respect to the controls were determined. All hypothesis tests used were two-tailed, with statistical significance assessed at the level of p< 0.05. Results: A total of 87 subfertile and 23 fertile men were included in the study. The mean MDA level was significantly higher in the subfertile subjects than in the fertile subjects, and the mean antioxidant level was significantly lower in the subfertile subjects than in the fertile subjects. Seminal MDA levels were negatively associated with sperm concentration, motility, and morphology, whereas the opposite was seen with TAC levels. Conclusion: Measurements of seminal TAC and ROS are valuable for predicting semen quality, and hence predicting the outcomes of fertility treatment.

• Advances in pediatric surgery
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• v.2 no.2
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• pp.143-147
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• 1996

Spontaneous perforation of the bile duct in children is a very rare disorder. We experienced a 6 year-old girl with spontaneous perforation of the right hepatic duct. The patient was initially misdiagnosed as hepatitis because of elevation of liver enzyme and then as appendicitis because of fluid collection in the pelvic cavity demonstrated by ultrasonogram. A laparoscopic exploration was done and no abnormal findings were detected except bile-stained ascites. Peritoneal drainage was performed and the patients seemed to improve clinically. Abdominal pain, distention and high fever developed after removal of the drains. DISIDA scan showed a possible of bile leak into the peritoneal cavity. ERCP demonstrated free spill of dye from the right hepatic duct. At laparotomy, the leak was seen in the anterior wall of the right hepatic duct 2cm above the junction of the cystic duct and common hepatic duct. The perforation was linear in shape and 0.8cm in size. The patient underwent cholecystectomy, primary closure of the perforation and T-tube choedochostomy. We could not identify the cause of the perforation; however, the T-tube cholangiography taken on the 42nd postoperative day showed a little more dilatation of the proximal common bile duct compared with the cholangiography taken on the 14th day. Long-term follow-up of the patient will be necessary because of the possibility for further change of the duct.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.14 no.3
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• pp.36-42
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• 2015

The aspherical lens was designed to be able to array a focal point. For this reason, it has very curved surface. The aspherical lens is fabricated by injection molding or diamond turning machine. With the aspherical lens, tool marks and surface roughness affect the optical characteristics, such as transmissivity. However, it is difficult to polish free form surface shapes uniformly with conventional methods. Therefore, in this paper, the ultra-precision polishing method with MR fluid was used to polish an aspherical lens with 4-axis position control systems. A Tool path and polishing mechanism were developed to polish the aspherical lens shape. An MR polishing experiment was performed using a generated tool path with a PMMA aspherical lens after the turning process. As a result, surface roughness was improved from $R_a=40.99nm$, $R_{max}=357.1nm$ to $R_a=4.54nm$, $R_{max}=35.72nm$. Finally, the MR polishing system can be applied to the finishing process of fabrication of the aspherical lens.

• Journal of Physiology & Pathology in Korean Medicine
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• v.28 no.2
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• pp.223-232
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• 2014

Most of salivary cortisol are an unbound free form reflecting physiological function later. Thus, it is used frequently to evaluate the HPA-Axis and physiological function. Although the needs of salivary cortisol measurement in Korean Medicine is higher and higher, there are not many studies, because the reliability of salivary cortisol measurement is not high. To make the reliability high and encourage to use it in Korean Medicine, the goal of this study is to suggest the standard method of saliva collecting for cortisol measurement through the review of previous studies using salivary cortisol and to encourage to use it in clinical fields in Korean Medicine. The results are as followed; First, salivary cortisol has many benefits, i. e. easy collecting, non-invasive collecting, and reflecting the physiological function. Second, the collecting time and method are kept sternly, because the methods of saliva collecting vary depending on the goal of study. Third, the specific tools for saliva collecting are recommended to prevent contamination. In conclusion, if the standard methods of saliva collecting is kept to measure salivary cortisol, it would be very useful in many fields of Korean Medicine.

• Wind and Structures
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• v.23 no.2
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• pp.91-107
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• 2016

Flow-excited acoustic resonance in ducted cavities can produce high levels of acoustic pressure that may lead to severe damage. This occurs when the flow instability over the cavity mouth, which is created by the free shear layer separation at the upstream edge, is coupled with one of the acoustic modes in the accommodating enclosure. Acoustic resonance can cause high amplitude fluctuating acoustic loads in and near the cavity. Such acoustic loads could cause damage in sensitive applications such as aircraft weapon bays. Therefore, the suppression and mitigation of these resonances are very important. Much of the work done in the past focused on the fluid-dynamic oscillation mechanism or suppressing the resonance by altering the edge condition at the shear layer separation. However, the effect of the downstream edge has received much less attention. This paper considers the effect of the impingement edge geometry on the acoustic resonance excitation and Strouhal number values of the flow instabilities in a ducted shallow cavity with an aspect ratio of 1.0. Several edges, including chamfered edges with different angles and round edges with different radii, were investigated. In addition, some downstream edges that have never been studied before, such as saw-tooth edges, spanwise cylinders, higher and lower steps, and straight and delta spoilers, are investigated. The experiments are conducted in an open-loop wind tunnel that can generate flows with a Mach number up to 0.45. The study shows that when some edge geometries, such as lower steps, chamfered, round, and saw-tooth edges, are installed downstream, they demonstrate a promising reduction in the acoustic resonance. On the other hand, higher steps and straight spoilers resulted in intensifying the acoustic resonance. In addition, the effect of edge geometry on the Strouhal number is presented.

• Advances in nano research
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• v.9 no.4
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• pp.263-276
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• 2020

In this article, the acoustic responses of free vibrated natural fibre-reinforced polymer nanocomposite structure have been investigated first time with the help of commercial package (ANSYS) using the multiphysical modelling approach. The sound relevant data of the polymeric structure is obtained by varying weight fractions of the natural nanofibre within the composite. Firstly, the structural frequencies are obtained through a simulation model prepared in ANSYS and solved through the static structural analysis module. Further, the corresponding sound data within a certain range of frequencies are evaluated by modelling the medium through the boundary element steps with adequate coupling between structure and fluid via LMS Virtual Lab. The simulation model validity has been established by comparing the frequency and sound responses with published results. In addition, sets of experimentation are carried out for the eigenvalue and the sound pressure level for different weight fractions of natural fibre and compared with own simulation data. The experimental frequencies are obtained using own impact type vibration analyzer and recorded through LABVIEW support software. Similarly, the noise data due to the harmonically excited vibrating plate are recorded through the available Array microphone (40 PH and serial no: 190569). The numerical results and subsequent experimental comparison are indicating the comprehensiveness of the presently derived simulation model. Finally, the effects of structural design parameters (thickness ratio, aspect ratio and boundary conditions) on the acoustic behaviour of the natural-fibre reinforced nanocomposite are computed using the present multiphysical model and highlighted the inferences.

• Journal of Korean Traditional Oncology
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• v.13 no.1
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• pp.1-11
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• 2008

Objectives: To grasp the traditional stream of cancer treatment inherited from the previous doctors. Methods: The author's research has been performed cancer treatment based on JIJU(積聚) taking the original text as a reference. Results & Conclusion: The general three outlines and five detailed rules of cancer treatment have been obtained as follows. The first outline of cancer treatment is that reinforced vital function makes cancer reduce naturally. the second is that Harmless cancer can coexist in human beings and aging with them. and the third is that Elimination and reinforcing therapies should be executed in appropriate era and those therapies should utilize appropriate methods. The first detailed rule of cancer treatment is when using reinforcing therapy, it must applicate mildly and when using elimination therapy, it must applicate calmly. The second detailed rule is that the methods of cancer treatment are different from each cancer stage. The concentration should be made on reinforcing therapy at early stage while reinforcing and elimination therapies must be conducted together at middle stage. At terminal stage reinforcing therapy is the sole method to be taken. The third detailed rule is that the basis property of cancer drug is warm nature and extremely biased property should be avoided and when complication arises (eg. inflamatory disease, cancer fever, etc), cold or cool nature can be applied. The fourth detailed rule is that Cancer drug must have the effect eliminating the blood stasis, phlegm and excessive fluid, all together. The fifth detailed rule is that Physicians have to control patient's stress or stress related symptom and teach patients about right way of taking care of themselves and patients should take hygienic rules with their free will by themselves (eg diet, exercise, stress, etc)

• Journal of Korean Neurosurgical Society
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• v.59 no.5
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• pp.505-511
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• 2016

Objective : Microvascular decompression (MVD) for hemifacial spasm (HFS) involving the vertebral artery (VA) can be technically challenging. We investigated the therapeutic effects of a bioglue-coated Teflon sling technique on the VA during MVD in 42 cases. Methods : A bioglue-coated Teflon sling was crafted by the surgeon and applied to patients in whom neurovascular compression was caused by the VA. The radiologic data, intra-operative findings with detailed introduction of the procedure, and the clinical outcomes of each patient were reviewed and analyzed. Results : The 42 patients included in the analysis consisted of 22 females and 20 males, with an average follow-up duration of 76 months (range 24-132 months). Intraoperative investigation revealed that an artery other than the VA was responsible for the neurovascular compression in all cases : posterior inferior cerebellar artery (PICA) in 23 patients (54.7%) and anterior inferior cerebellar artery (AICA) in 11 patients (26.2%). All patients became symptom-free after MVD. Neither recurrence nor postoperative neurological deficit was noted during the 2-year follow-up, except in one patient who developed permanent deafness. Cerebrospinal fluid (CSF) leak occurred in three patients, and one required dural repair. Conclusion : Transposition of the VA using a bioglue-coated Teflon sling is a safe and effective surgical technique for HFS involving the VA. A future prospective study to compare clinical outcomes between groups with and without use of this novel technique is required.

• Journal of Korean Neurosurgical Society
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• v.59 no.5
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• pp.512-517
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• 2016

Objective : The pathophysiology of idiopathic Chiari malformation (CM) type 1 is disturbance of free cerebrospinal fluid (CSF) flow and restoration of normal CSF flow is the mainstay of treatment. Additional migration of the medulla oblongata in pediatric patients is referred to as CM type 1.5, but its significance in adult patients is unknown. This study is to compare surgical outcomes of adult idiopathic CM type 1.5 with that of type 1. Methods : Thirty-eight consecutive adult patients (M : F=11 : 27; median, 33.5; range, 18-63) with syringomyelia due to idiopathic CM type 1 were reviewed. Migration of the medulla oblongata was noted in 13 patients. The modified McCormick scale (MMS) was used to evaluate functional status before and one year after surgery. All patients underwent foramen magnum decompression and duroplasty. Factors related to radiological success (${\geq}50%$ decrease in the diameter of the syrinx) were investigated. The follow-up period was $72.7{\pm}55.6$ months. Results : Preoperative functional status were MMS I in 11 patients and MMS II in 14 of CM type 1 and MMS I in 8 and II in 5 of CM type 1.5. Of patients with MMS II, 5/14 patients in group A and 3/5 patients in group B showed improvement and there was no case of deterioration. Radiological success was achieved in 32 (84%) patients and restoration of the cisterna magna (p=0.01; OR, 46.5) was the only significant factor. Conclusion : Migration of the medulla oblongata did not make a difference in the surgical outcome when the cisterna magna was restored.