• Proceedings of the Korean Society of Applied Pharmacology
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• 2000.04a
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• pp.6-7
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• 2000

Recently, free radicals such as active oxygen species, nitric oxide, etc are believed to be one of the key substances in physiological and pathological, toxicological phenomena, and oxidative damages, and all organism have defencing system against such as free radicals. Formation and extinction of free radicals may be regulated through bio-redox system, in which various enzymes and compounds should be involved in very complicated manner. Thus, direct and non-invasive measurement of in vivo free radical reactions with living animals must be essential to understand the role of free radicals in pathophysiological phenomena. Electron spin resonance spectroscopy (ESR) is very selective and sensitive technique to detect free radicals, but a conventional ESR spectrometer has large detect in application to living animals, since high frequent microwave is absorbed with water, resulting in generation of high fever in living body. In order to estimate in vivo free radical reactions in living whole animals, we develop in vivo ESR-CT technique using nitroxide radicals as spin probes. Nitroxide radicals and their reduced forms, hydroxylamines, are known to interact with various redox systems. We found that! ! the signal decay due to reduction of nitroxyl radicals is influenced by aging, inspired oxygen concentration, ischemia-referfusion injury, radiation, etc. In the present paper, I will introduce in vivo ESR technique and my laboratory recent results concerning non-invasive evaluation of free radical reactions in living mice.

• KIEAE Journal
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• v.1 no.2
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• pp.21-28
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• 2001

Naturally-ocurring short-lived decay products of radon gas in indoor air are the dominant source of ionizing radiation exposure to the general public. It is written in BEIR VI Report(l999l the radon progeny were identified as the second cause of lung cancer next to cigarette or 10 % to 14 %(15,400 to 21,800 persons p.a.) of all lung cancer deaths in USA. Indoor radon concentrations in houses typically result from radon gaining access to houses mainly from the underlying soil. In the States, they have "Indoor Radon Abatement Act" which was converted from "Toxic Substance Control Act" in 1988 to establish the national long-term goal that indoor air should be as free of radon as the ambient air outside of buildings. To review and study techniques for controlling radon, two test cells were constructed for a series of tests and are under measuring indoor and soil gas (underneath of floor slab)radon concentrations according to EPA's measurement protocol. In this paper, important theoretical studies are previewed and the following paper will explain the test results and confirm the theories reviewed to find out suitable coefficients. On the basis of test analysis, it will be described and evaluated various techniques that can be used to mitigate elevated indoor concentration of radon including the control of radon and its decay products.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.11 no.8
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• pp.646-651
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• 1998

In this present study, the luminescence characteristics and mechanism of energy $CaTiO_3$:Pr phosphor were studied using disk specimens sintered at various temperatures and envirenment. A single-phase $CaTiO_3$:Pr was synthesized by sintering above 140$0^{\circ}C$ and its crystal structure was found to be perovskite orthorhombic. A dominant peak around 360 nm and a broad peak around 395 nm were observed in the PLE(Photoluminescence Excitation) spectrum of $CaTiO_3$:Pr with fixed emission wavelength at 612 nm, the decay time of 360 nm excitation was found to be longer than that of 395 nm excitation. From this result, it is assumed that the free carrier excited to 360 nm is transferred to 395 nm energy level. Therefore, the decrease in 395 nm intensity observed in CaTiO$_3$:Pr specimens sintered in Ar gas environment induced shorter decay time and improved CL luminescence.

• Journal of the Korean Society of Industry Convergence
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• v.4 no.4
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• pp.387-393
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• 2001

The flow characteristics on the centerline in case of free jet, sudden expansion jet and impinging jet have been investigated. Centerline flow behaviors and similaritis with mean velocities, turbulent intensities, shear stresses, isotropic structures and turbulent kinetic energies on the streamwise direction were looked into and compared with three jets, The results show that mean velocities have represented potential core and decayed with similar gradients. The turbulent intensities and shear stresses were presented peak values in the self-preserving region, and then they were in decay. Aeolotropy in the initial region were possible returned to isotropy patterns with asymptotic approach in the downstream region. It has been found that the turbulent kinetic energies for the three cases of jet existed in the similarity and they coincided with Gaussian profile.

• Journal of the Korean Society of Marine Environment & Safety
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• v.21 no.5
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• pp.538-542
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• 2015

The transverse moment of inertia is an indispensable factor in analyzing the roll motion characteristics of ships and the calculating method needs to be based on the more reasonable theories when deciding the value as the results and reliability of analysis could be much affected by the correctness. However, the mass distribution and shape of hulls are quite complicated and give much difficulties in case of calculating the value directly from the ship design data, furthermore even acquiring the detailed design data for calculation is almost impossible. Therefore some simpler ways are practically adopted in the assumption that the gyradius of roll moment can be decided by a given ratio and hull width. It is well known that the responses of the free roll decay are varied according to the value of roll moment in view of roll period and amplitude decay ratio, so that the general formula to get the moment value can be derived also from the observation of roll decay responses. This study presents how the roll period and decay ratio are interrelated each other from the roll motion characteristics with suggesting a general formula to be able to calculate roll moment from it. Finally, the obtained general formula has been applied to a ship data to check the resultant characteristics through analyzing graphs and showed that the roll moment becomes more accurate when rolling period and decay ratio are considered together in calculation.

• Journal of Environmental Health Sciences
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• v.27 no.1
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• pp.27-35
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• 2001

This aim of the work presented in this paper is to investigate the factors that affcet chlorine decay and to develop functional relationships that can be used to enhance the durability of network models. predictive relationships were established that correlated the rate of chlorine decay to the various water conditions such as DOC, N $H_3$-N, initial chlorine, contact time, temperature and pH values. Free chlorine residual decreased with increasing temperature, DOC, N $H_3$-N, reaction time and chlorine dose. At 2$0^{\circ}C$, pH 7, The initial chlorine demand per mg as DOC/L and mg as N $H_3$-N/L was about 0.43, 2.69 mg/$\ell$ respectively at 180 minutes contact time. The Reaction between chlorine and humic acids was lasted intil 48hr, but the reaction between chlorine and N $H_3$-N was almost completed in 180 min. When the temperature is raised by 1$0^{\circ}C$, chlorine is more consumed about 0.25 mg/$\ell$ in the absence of organic substances and it is more consumed about 3.4 mg/$\ell$ in the presence of humic acid (5 mg/$\ell$) in water at pH 7 for 180 min. Regression Analysis created the resulting prediction equation for the chlorine decay in a SPSS package of the computer system. The model is as follows; $C_{t}$=1.239+0.707(Co)-0.000529(Time)-0.0112(Temp)+0.02227(pH)-0.42(DOC)-2.132(N $H_3$-N).).

• BMB Reports
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• v.40 no.4
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• pp.453-458
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• 2007

Bacterial luciferase is a heterodimeric enzyme, which catalyzes the light emission reaction, utilizing reduced FMN (FMNH2), a long chain aliphatic aldehyde and $O_2$, to produce green-blue light. This enzyme can be readily classed as slow or fast decay based on their rate of luminescence decay in a single turnover. Mutation of Glu175 in $\alpha$ subunit to Gly converted slow decay Xenorhabdus Luminescence luciferase to fast decay one. The following studies revealed that changing the luciferase flexibility and lake of Glu-flavin interactions are responsible for the unusual kinetic properties of mutant enzyme. Optical and thermodynamics studies have caused a decrease in free energy and anisotropy of mutant enzyme. Moreover, the role of Glu175 in transition state of folding pathway by use of stopped-flow fluorescence technique has been studied which suggesting that Glu175 is not involved in transition state of folding and appears as surface residue of the nucleus or as a member of one of a few alternative folding nuclei. These results suggest that mutation of Glu175 to Gly extended the structure of Xenorhabdus Luminescence luciferase, locally.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.15 no.2
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• pp.209-218
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• 2002

The Vector Random Decrement technique has been developed as an efficient method for transforming ambient responses into free decays of linear structures. It is shown that the VRD functions nay contain as much information about the modes as the really measured free decay responses. In this paper, the theory of the VRD technique is extended by applying the concept of the mode shape ratio into the Ibrahim Time Domain modal parameter identification algorithm. The VRD function is not shifted in the correction procedures for constant time shifts of the proposed VRD technique. Thus, a number of points equal to the largest of the time shifts used in the vector triggering condition are not deleted. In the VRD functions, any influence of the input to the system is averaged out. The proposed technique is compared with the traditional VRD technique by assessment of the modal parameters. The applicability of the VRD technique has been justified through a simulation study and a study of the response of a laboratory beam model subject to ambient loads.

• Journal of Ocean Engineering and Technology
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• v.33 no.2
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• pp.131-138
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• 2019

This study focused on the roll motion characteristics of a two-dimensional (2D) rectangular floating structure under regular beam sea conditions. An experiment was conducted in a 2D wave tank for a roll free decay test in calm water and the roll motion in a range of regular waves with and without heave motion to investigate the motion response and heave influence on the roll motion. A numerical study was carried out using Reynolds-averaged Navier Stokes (RANS)-based CFD simulations. A grid convergence test was conducted to accurately capture the wave condition on the free surface based on the overset mesh and wave forcing method. It was found in the roll free decay test that the numerical results agreed well with the experimental results for the natural roll period and roll damping coefficient. It was also observed that the heave motion had an impact on the roll motion, and the responses of the heave and roll motion from the CFD simulations were in reasonable agreement with those from the experiment.

• Geophysics and Geophysical Exploration
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• v.11 no.2
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• pp.116-126
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• 2008

In gas hydrate survey, seismic amplitude and frequency characteristics play a very important role in determining whether gas hydrate exists. According to the variation of source frequency and scatterer size, we study seismic amplitude characteristics using elastic modeling applied at staggered grids. Generally speaking, scattering occurs in proportion to the square of source frequency and the scatterer volume, which has an effect on seismic amplitude. The higher source frequency is, the more scattering occurs in gas hydrate bearing zone. Therefore, BSR is hardly observed in high frequencies. On the other side, amplitude blanking zone and BSR is clearly observed in lower frequencies although the resolution is poor as a whole. Seismic reflections traveling through free-gas layer below gas hydrate bearing zone decay so severely a high frequency component that a low frequency term is dominant. Amplitude anomaly of BSR result from high acoustic impedance contrast due to free-gas, which is a very crucial factor to estimate gas hydrate bearing zone. Seismic frequency analysis is carried out using wavelet transform method that frequency component could be decomposed with time variation. In application of wavelet transform to the seismic physical experiments data, we can observe that reflections traveling through air layer, which corresponds to the free-gas layer, decay a high frequency component.