• Title/Summary/Keyword: Free Water

Search Result 3,579, Processing Time 0.032 seconds

The Inhibition of UVA-induced Matrix Metalloproteinase-1 in Human Dermal Fibroblasts and the Improvement of Skin Elasticity by Cirsium setidens Extract (고려엉겅퀴 추출물의 사람 섬유아세포에 있어서 자외선으로 유도된 MMP-1발현 저해와 피부 탄력 개선 효과)

  • Sim, Gwan-Sub;Kim, Jin-Hwa;Lee, Dong-Hwan;Lee, Bum-Chun;Lee, Geun-Soo;Pyo, Hyeong-Bae
    • Journal of the Society of Cosmetic Scientists of Korea
    • /
    • v.33 no.3
    • /
    • pp.181-187
    • /
    • 2007
  • In this study, we measured the anti-oxidative activity of Cirsium setidens and investigated its effect on UVA-induced MMP-1 expression in human dermal fibroblats. And then we examined possible improvement in skin elasticity by topical treatment with fomular including Cirsium setidens extract. The ethanol extract of C. setidens showed free anion radical scavenging effect(87.47 % at 1 mg/mL) and superoxide anion radical scavenging effect(61.71 % at 1 mg/mL) in the xanthine/xanthine oxidase system, respectively. At the concentration of 100 ${\mu}g/mL$, C. setidens extract showed 95.54% inhibition on lipid peroxidation of linoleic acid. UVA-induced MMP-1 expression in human dermal fibroblasts was reduced to 54.69 % by treatment with 100 ${\mu}g/mL$ of C. setidens extract. A human clinical study, in which oil-in-water emulsion with C. setidens extract was topically applied, showed significant increase in skin elasticity. These results suggest that the C. setidens extract can be effective anti-aging ingredient for cosmetics applications.

Development of a Method to Analyze Powering Performance of a Ship and its Application to Optimum Hull Form Design (선박(船舶)의 정수중(靜水中) 추진성능(推進性能) 해석(解析) 및 최적선형설계(最適船型設計)에의 응용(應用))

  • Seung-Il,Yang
    • Bulletin of the Society of Naval Architects of Korea
    • /
    • v.22 no.2
    • /
    • pp.35-48
    • /
    • 1985
  • The present work develops a method of evaluating thrust deduction and wake for different loads of the propeller using the concerted application of the theoretical tools and experimental techniques. It also shows the applicability of the new method to the design of optimum hull form. Firstly, the problem of hull-propeller interaction was analyzed in terms of inviscid as well as viscous components of the thrust deduction and wake. The wavemaking resistance of a hull and propeller were mathematically represented by sources on the hull surface and sink on the propeller plane, respectively. The strength of sink was determined by utilizing the radial distributions of propeller load and nominal wake. The resistance increment due to a propeller and the axial perturbation flow induced by the hull in the propeller plane were calculated. Especially, the inviscid component of the thrust deduction was calculated by subtraction the wavemaking resistance of a bare hull, the wavemaking resistance of a free-running propeller and the augmentation of propeller resistance due to hull action from the wavemaking resistance of the hull with a propeller. The viscous components of the thrust deduction and wake were estimated as functions of propeller load which were established by the propeller load varying test after deduction the calculated inviscid components. Secondly, an analysis method of powering performance was developed based on the potential theory and the propeller load varying test. The hybrid method estimates the thrust deduction, wake and propeller open-water efficiency for different propeller load. This method can be utilized in the analysis of powering performance for the propeller load variation such as the added resistance due to hull surface roughness, the added resistance due to wind, etc. Finally, the hybrid method was applied to the optimum design of hull form. A series of afterbody shapes was obtained by systematically varying the waterplane and section shapes of a parent afterbody without changing the principal dimensions, block coefficient and prismatic coefficient. From the comparison of the predicted results such as wavemaking resistance, thrust deduction, wake and delivered power, an optimum hull form was obtained. The delivered power of the optimized hull form was reduced by 5.7% which was confirmed by model tests. Also the predicted delivered power by the hybrid method shows fairly good agreement with the test result. It is therefore considered that the new analysis method of powering performance can be utilized as a practical tool for the design of optimum hull form as for the analysis of powering performance for the propeller load variation in the preliminary design stage.

  • PDF

New Boron Compound, Silicon Boride Ceramics for Capturing Thermal Neutrons (Possibility of the material application for nuclear power generation)

  • Matsushita, Jun-ichi
    • Proceedings of the Materials Research Society of Korea Conference
    • /
    • 2011.05a
    • /
    • pp.15-15
    • /
    • 2011
  • As you know, boron compounds, borax ($Na_2B_4O_5(OH)_4{\cdot}8H_2O$) etc. were known thousands of years ago. As for natural boron, it has two naturally occurring and stable isotopes, boron 11 ($^{11}B$) and boron 10 ($^{10}B$). The neutron absorption $^{10}B$ is included about 19~20% with 80~81% $^{11}B$. Boron is similar to carbon in its capability to form stable covalently bonded molecular networks. The mass difference results in a wide range of ${\beta}$ values between the $^{11}B$ and $^{10}B$. The $^{10}B$ isotope, stable with 5 neutrons is excellent at capturing thermal neutrons. For example, it is possible to decrease a thermal neutron required for the nuclear reaction of uranium 235 ($^{235}U$). If $^{10}B$ absorbs a neutron ($^1n$), it will change to $^7Li+^1{\alpha}$ (${\alpha}$ ray, like $^4He$) with prompt ${\gamma}$ ray from $^{11}B$ $^{11}B$ (equation 1). $$^{10}B+^1n\;{\rightarrow}\;^{11}B\;{\rightarrow}\; prompt \;{\gamma}\;ray (478 keV), \;^7Li+4{\alpha}\;(4He)\;\;\;\;{\cdots}\; (1)$$ If about 1% boron is added to stainless steel, it is known that a neutron shielding effect will be 3 times the boron free steel. Enriched boron or $^{10}B$ is used in both radiation shielding and in boron neutron capture therapy. Then, $^{10}B$ is used for reactivity control and in emergency shutdown systems in nuclear reactors. Furthermore, boron carbide, $B_4C$, is used as the charge of a nuclear fission reaction control rod material and neutron cover material for nuclear reactors. The $B_4C$ powder of natural B composition is used as a charge of a control material of a boiling water reactor (BWR) which occupies commercial power reactors in nuclear power generation. The $B_4C$ sintered body which adjusted $^{10}B$ concentration is used as a charge of a control material of the fast breeder reactor (FBR) currently developed aiming at establishment of a nuclear fuel cycle. In this study for new boron compound, silicon boride ceramics for capturing thermal neutrons, preparation and characterization of both silicon tetraboride ($SiB_4$) and silicon hexaboride ($SiB_6$) and ceramics produced by sintering were investigated in order to determine the suitability of this material for nuclear power generation. The relative density increased with increasing sintering temperature. With a sintering temperature of 1,923 K, a sintered body having a relative density of more than 99% was obtained. The Vickers hardness increased with increasing sintering temperature. The best result was a Vickers hardness of 28 GPa for the $SiB_6$ sintered at 1,923K for 1 h. The high temperature Vickers hardness of the $SiB_6$ sintered body changed from 28 to 12 GPa in the temperature range of room temperature to 1,273 K. The thermal conductivity of the SiB6 sintered body changed from 9.1 to 2.4 W/mK in the range of room temperature to 1,273 K.

  • PDF

Effect of Freezing on the Physicochemical Properties of Semi-dried Red Pepper (냉동조건에 따른 반건조 홍고추의 물리.화학적 특성 변화)

  • Kim, Bo-Yeon;Lee, Kyoung-Hae
    • Food Science and Preservation
    • /
    • v.16 no.3
    • /
    • pp.362-370
    • /
    • 2009
  • Quality changes in semi-dried red pepper (SRP) treated with ozone water were observed upon storage (at $-18^{\circ}C$) after freezing at $-10^{\circ}C$, $-20^{\circ}C$, and $-40^{\circ}C$. Drip loss after treatment was greater than in control peppers, but no significant difference was evident between treatments (p<0.05). We observed that differences between samples decreased as storage time increased. Texture after treatment did not change significantly over a 3-month period. The redness (a-value) after treatment was greater than in the control, but no sample showed significant color alteration after the 3-month period. The capsaicinoid content decreasedas storage time increased, and was also affected by the freezing temperature. However, carotenoid content was not influenced by freezing or storage temperature. Ascorbic acid and free sugar contents showed decreases of 47% and 6.5%, respectively, after semi-drying. The results of sensory evaluation indicated no significant difference between samples in terms of color appearance.

Studies on the Processing and Utilization of Seaweeds - Studies on the Processing of Sea Mustard Jam- (해조류의 가공 및 이용에 관한 연구 -미역쨈의 제조에 관한 연구-)

  • CHA Yong-Jun;LEE Eung-Ho;PARK Du-Cheon
    • Korean Journal of Fisheries and Aquatic Sciences
    • /
    • v.21 no.1
    • /
    • pp.42-49
    • /
    • 1988
  • In order to utilize sea mustard, Undaria pinnatifida, effectively. sea mustard jam was prepared by use of physical properties of polysaccharides, mainly alginic acid and then its chemical composition, nutritive qualifies and the stability of pigments were examined. Suitable processing condition for sea mustard jam was as fellows : as the first stage, fresh sea mustard was scalded for 20 sec at $85^{\circ}C$ and dried sea mustard was dipped for 20 min in cold water for rehydration, then both sea mustards were treated by draining and chopping. Next, after adding 4 fold of $0.5\%\;K_2HPO_4$ solution to weight of chopped sea mustards, the mixed solutions were agitated for 15 min at $95^{\circ}C$, and gelated sea mustards were filterated by pressing. Flow characteristics of those sea mustard jam were regarded mixed type having pseudoplastic type and yield stress. Judging from sensory evaluation, adding $0.375\%$ of saccharin, $2\%$ of sorbitol, $0.25\%$ of citric acid and $0.5\%$ of powder of roasted soybean to sea mustard jam were suitable for enhancing taste and flavor of product. Chemical composition of products were scarcely changed throughtout processing. Jam processed by fresh sea mustard was better than dried one in contents of chlorophyll and total carotenoid pigments. In fatty acid composition, polyenoic acids of $C_{18:3},\;C_{20:4},\;C_{20:5},\;C_{22:6}$ were held high contents as known to have lowering function of cholesterol contents. It was presumed that dominant contents in free amino acids such as lysine, alanine, glutamic acid and organic acids such as citric acid, oxalic acid, $\alpha-ketoglutaric$ acid, lactic acid and succinic acid held important role for the flavor of sea mustard jam.

  • PDF

Skin-Friction Drag Reduction in Wake Region by Suction Control on Horseshoe Vortex in front of Hemisphere (반구 전방에 생성된 말굽와류 흡입제어에 의한 후류영역 마찰저항 감소에 관한 연구)

  • Koo, Bonguk;Kang, Yong-Duck
    • Journal of the Korean Society of Marine Environment & Safety
    • /
    • v.25 no.6
    • /
    • pp.795-801
    • /
    • 2019
  • The aim of this study was to investigate the possibility of the skin-friction reduction by vortex control. A vortical system such as a horseshoe vortex, a hairpin vortex, and a wake region was induced around a hemisphere attached on a Perspex flat plate in the circulating water channel. Hairpin vortices were developed from the wake region and horseshoe vortices were formed by an adverse pressure gradient in front of the hemisphere. The horseshoe vortices located on the flank of the hemisphere induced a high momentum flow in the wake region by the direction of their vorticity. This process increased the frequency of the hairpin vortices as well as the frictional drag on the surface of the wake region. To reduce the skin-friction drag, suction control in front of the hemisphere was applied through a hole. Flow visualization was performed to optimize the free-stream velocity, size of the hemisphere, and size of the suction hole. Once the wall suction control mitigated the strength of the horseshoe vortex, the energy supplied to the wake region was reduced, causing the frequency of the hairpin vortex generation to decrease by 36.4 %. In addition, the change in the skin-friction drag, which was measured with a dynamometer connected to a plate in the wake region, also decreased by 2.3 %.

Effects of Roasting Conditions on Components of Safflower(Carthamus tinctorius L.) Seed (홍화(紅花) 종실(種實)의 볶음 조건에 따른 성분(成分)의 변화(變化))

  • Park, Jun-Hong;Kim, Ki-Jae;Kim, Jae-Chul;Kim, Se-Jong;Park, So-Deuk
    • Korean Journal of Medicinal Crop Science
    • /
    • v.8 no.3
    • /
    • pp.194-200
    • /
    • 2000
  • The main objective of this study was to characterize physico-chemical properties, sensory property and oxidative stability of safflower seed obtained by various roasting temperature and time. The contents of water soluble solids decreased in the higher roasting temperature and time. Sensory evaluation of safflower seed roasted in various conditions showed significant differences in taste, color, flavor and palatability. The safflower seed roasted at $190^{\circ}C$ for 20min had the best palatability. At the change of Hunter's values, L values were decreased, and a, b and ${\Delta}E$ values were increased in the higher roasting temperature and time. The content of free sugars such as sucrose and raffinose were reduced significantly in higher roasting time of $190^{\circ}C$ and $210^{\circ}C$. During the storage period after roasting treatment, peroxide values (POV) were highly increased after eight months at the all treatment except for $150^{\circ}C$. Therefore, it is inadequate over eight months after roasting treatment.

  • PDF

The Effect of Porous Support and Intermediate Layer on the Silica-zirconia Membranes for Gas Permeation Performance (실리카-지르코니아 분리막 성능에 대한 다공성 지지체와 중간층의 영향)

  • Lee, Hye Ryeon;Seo, Bongkuk
    • Membrane Journal
    • /
    • v.25 no.1
    • /
    • pp.15-26
    • /
    • 2015
  • In this study, porous metal (O.D. = 10 mm, length = 10 mm, 316 L SUS, Mott Corp.) and ${\alpha}$-alumina tube (O.D. = 10 mm, length = 50 mm, Pall, German) support was modified with suspension sols, which were consisted of $3{\sim}4{\mu}m$ and 150 nm size of ${\alpha}$-alumina particle in the water or silica-zirconia colloidal sol. The porous support was fabricated by dip coating method for 5 seconds with suspension of alumina particles. After drying at $100^{\circ}C$ for 1 h, it was calcined at $550^{\circ}C$ for 30 min. It was repeated several times in order to decrease big pore on support. The surface roughness and largest pore size on the porous support was decreased by increasing coating times with $3{\sim}4{\mu}m$ size of ${\alpha}$-alumina particle and alumina coating with 150 nm size of ${\alpha}$-alumina particle served as further smoothening the surface and decreasing the pore size of the substrate. And the silica-zirconia membranes were successfully prepared on the modified porous metal and ${\alpha}$-alumina supports, and showed hydrogen permeance in the range of $1.8-8.4{\times}10^{-4}mol{\cdot}m^{-2}{\cdot}s^{-1}{\cdot}Pa^{-1}$ and $3.3-5.0{\times}10^{-5}mol{\cdot}m^{-2}{\cdot}s^{-1}{\cdot}Pa^{-1}$, respectively.

Upregulation of Mir-34a in AGS Gastric Cancer Cells by a PLGA-PEG-PLGA Chrysin Nano Formulation

  • Mohammadian, Farideh;Abhari, Alireza;Dariushnejad, Hassan;Zarghami, Faraz;Nikanfar, Alireza;Pilehvar-Soltanahmadi, Yones;Zarghami, Nosratollah
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.16 no.18
    • /
    • pp.8259-8263
    • /
    • 2016
  • Background: Nano-therapy has the potential to revolutionize cancer therapy. Chrysin, a natural flavonoid, was recently recognized as having important biological roles in chemical defenses and nitrogen fixation, with anti-inflammatory and anti-oxidant effects but the poor water solubility of flavonoids limitstheir bioavailability and biomedical applications. Objective: Chrysin loaded PLGA-PEG-PLGA was assessed for improvement of solubility, drug tolerance and adverse effects and accumulation in a gastric cancer cell line (AGS). Materials and Methods: Chrysin loaded PLGA-PEG copolymers were prepared using the double emulsion method (W/O/W). The morphology and size distributions of the prepared PLGA-PEG nanospheres were investigated by 1H NMR, FT-IR and SEM. The in vitro cytotoxicity of pure and nano-chrysin was tested by MTT assay and miR-34a was measured by real-time PCR. Results: 1H NMR, FT-IR and SEM confirmed the PLGA-PEG structure and chrysin loaded on nanoparticles. The MTT results for different concentrations of chrysin at different times for the treatment of AGS cell line showed IC50 values of 68.2, 56.2 and $42.3{\mu}M$ and 58.2, 44.2, $36.8{\mu}M$ after 24, 48, and 72 hours of treatment, respectively for chrysin itslef and chrysin-loaded nanoparticles. The results of real time PCR showed that expression of miR-34a was upregulated to a greater extent via nano chrysin rather than free chrysin. Conclusions: Our study demonstrates chrysin loaded PLGA-PEG promises a natural and efficient system for anticancer drug delivery to fight gastric cancer.

[ $CO_2$ ] Content in Golf Green Rhizosphere (골프장 putting green 근권(根圈)에서의 이산화탄소 $(CO_2)$ 함유량)

  • Chong S. K.;Boniak Richard;Indorante S.;Ok C. H.;Buschschulte D.
    • Asian Journal of Turfgrass Science
    • /
    • v.18 no.2
    • /
    • pp.97-104
    • /
    • 2004
  • Anaerobic soils limit the amount of free oxygen available in the rhizosphere and therefore will impede grass root development and restrain nutrient availability for turf growth. An in-situ study was conducted on existing greens to investigate the relationship between $CO_2$ content in the rhizosphere and turf quality. Nine greens were selected in the study. On each green, five 1-m diameter circular plots were randomly selected for conducting the experiment. The greens were sampled 7 times from August, 1998 to August, 1999. Data collected from each plot included turf quality index, $CO_2$ content, and physical properties of the rooting mixtures. Turf quality declined drastically when $CO_2$ content in rhizosphere increased to $5\;to\;6{\mu}LL^{-1}$ during the late summer season. The $CO_2$ content increased as water content in the root zone increased, but was inversely related to infiltration rate. Cultivation of a golf green may reduce $CO_2$ content in the rhizosphere, but the benefit of cultivation decreased with time.