• The Journal of the Korea Contents Association
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• v.11 no.2
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• pp.367-375
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• 2011

This study conducts analysis on integrated care cases in Korea and other nations regarding health, medical, and welfare services that are segmented and fragmented in order to provide foundational data to establish an integrated care system appropriate for the situation of Korea. According to the result of the cases, integrated care provides various services in common through cooperation with organizations, collaborative participation of various professionals, provision of intervention and individualized protection, and experts for taking care of the cases. Based on those cases, this paper provides suggestions to establish an integrated care system of Korea. In fact, it is necessary to build integrated care general support centers, arrange service providing places in common, establish a care management system, develop resources and expand manpower, develop an integrated care case management system, and develop integrated care computer network.

• Journal of Astronomy and Space Sciences
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• v.3 no.1
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• pp.1-13
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• 1986

A long-term project(ten-year ; 1982-92) for the photoeletric observation in the UBV passbands of selected eclipsing binaries with P$\geq$10 days has initiated at Yonsei University Observatory using 40-cm and 61-cm reflectors. the instrumentatio used and the observation techniques and the reduction procedures applied to this investiagation are described. Out of 39 program stars, successful results have been obtained during our first two years for the 11 stars listed below, with the orbital period in days in the parenthesis, and the incomplete light curves of these stars are presented. SX Cas (36.57) AQ Cas (11.72) UU Cnc (96.71) RY Gem (9.30) V373 Cas (13.42) NY Cep (15.28) RX Cas (32.32) V396 Cas (15.28) ZZ Cnc (25.60) Zet Aur (982.2) Eps Aur (9885.) For the rest of the stars, the observations made in the first two years are not sufficient to attempt any meaning light curve construction ; some of the data are too fragmented and others show large scatter.

• Journal of Digital Convergence
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• v.11 no.3
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• pp.101-113
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• 2013

Although the methodological literature is replete with advice regarding the development and validation of multi-item scales based on reflective measures, the issue of index construction using formative measures has received little attention. The aim of this paper is to enhance researchers' understanding of formative measures of high-order factor and assist them in their index construction efforts. This article is also to provide some insights into the nature of formative indicators for researchers to reach an informed choice as to the appropriate high order formative measurement model for their needs. We first provide a brief background on formative indicators, drawing from the limited and fragmented literature on the topic. Next we give an example of constructing an index based on actual survey data and highlight the procedures used to assess its quality. We conclude the article with some thoughts about the use of indexes in empirical studies.

• The Journal of Korean Obstetrics and Gynecology
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• v.18 no.3
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• pp.77-91
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• 2005

Purpose : Trichosanthis Radix is traditional medical herb which has been shown to inhibit tumor cell proliferation. In this study, the effects of Trichosanthis Radix extract were investigated on inducing growth inhibition and apoptosis of human uterine cervical carcinoma cells. Methods : Human uterine cervical carcinoma cells line, ME-180, was used for the study. The cells were treated with varying concentrations of Trichosanthis Radix extract. Cell growth and inhibitory rate were measured by MTT assay. Apoptosis induction was detected by fluorescence microscopy, DNA ladder formation and flow cytometry. Results : Trichosanthis Radix extract inhibited the growth of human uterine cervical carcinoma cells in a dose-dependent manner. It induced ME-180 cells to undergo apoptosis including fragmented nuclei and nucleosome-sized DNA fragmentation. Flow cytometric analysis showed the increasing rate of apoptotic cells by Trichosanthis Radix extract. Reduction of mitochondrial membrane potential and increase in caspase-3 activity and were found in ME-180 cells treated with Trichosanthis Radix extract. Conclusion : Our data suggest that Trichosanthis Radix extract inhibit the growth and proliferation of ME-180 cells by apoptotic induction and facilitates its activity via caspase-3 activation initiated by depolarization of mitochondria.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• v.9 no.1
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• pp.590-593
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• 2005

In this paper, it is analyzed a transmission time of ACL Packet in bluetooth wireless link. In order for segment to improve the transfer capability in bluetooth system, it is fragmented in TCP total messages that are coming down from upper layer and then the packets are sent one at time in baseband. And it is studied that transmission time for bluetooth wireless link according to DM1, DM3 or DM5 packet type in bluetooth piconet environment. From the results, we were able to obtain ACL packet transmission time, optimal TCP packet size and DM packet size.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• v.9 no.2
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• pp.553-556
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• 2005

It is analyzed that WAP packet transmission time to improve performance of WAP using SAR algorithm in Bluetooth channel. The order for SAR algorithm to improve the transfer capability, it is fragmented in WTP total messages that are coming down from upper layer and then the packets are sent one at time in baseband. And it is studied that transmission time for WAP over bluetooth according to DM1, DM3 or DM5 packet type using SAR algorithm in Bluetooth piconet environment. This SAR algorithm decreases WAP packet transmission time of L2CAP baseband packets by sending packet which are spanning multiple slots.

• Journal of Environmental Impact Assessment
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• v.12 no.1
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• pp.1-8
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• 2003

The Master Plan of Natural Environment Conservation in Korea by Ministry of Environment has been carried out since 1986. The 2nd 10-year survey started in 1997, and there are three major parts in the Master Plan : First, the basic natural environment survey, second, sites in special features of ecological characteristics such as uninhabitable islands, wetlands, etc, and third, biological species featuring status of habitat, and population dynamics. However the information in the Master Plan is very fragmented and collected data are not so abundant due to insufficient man-power and unsynchronized survey time/season. In this regard this paper examined the similar National Biological Survey in USA and compared the differences with the Master Plan in Korea. The Master Plan in Korea should separate the management zone based on hydrological characteristics, and in each zone we should set a management goal in the long term basis. Secondly the species list is not so meaningful that we must concentrate more on research activities. In each taxonomical group we set up hypotheses and research goals. Thirdly local residents and communities should be involved in research so that enhanced biological diversity should benefit people in areas. Lastly legislation and laws should be reexamined and rectified to provide information to the managers that deals with natural resources, expecially when conflicting with economic matters.

• Journal of Information Processing Systems
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• v.16 no.3
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• pp.718-732
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• 2020

Conducting sentiment analysis and opinion mining are challenging tasks in natural language processing. Many of the sentiment analysis and opinion mining applications focus on product reviews, social media reviews, forums and microblogs whose reviews are topic-similar and opinion-rich. In this paper, we try to analyze the sentiments of sentences from online webcast reviews that scroll across the screen, which we call live barrages. Contrary to social media comments or product reviews, the topics in live barrages are more fragmented, and there are plenty of invalid comments that we must remove in the preprocessing phase. To extract evaluative sentiment sentences, we proposed a novel approach that clusters the barrages from the same commenter to solve the problem of scattering the information for each barrage. The method developed in this paper contains two subtasks: in the data preprocessing phase, we cluster the sentences from the same commenter and remove unavailable sentences; and we use a semi-supervised machine learning approach, the naïve Bayes algorithm, to analyze the sentiment of the barrage. According to our experimental results, this method shows that it performs well in analyzing the sentiment of online webcast barrages.

• BMB Reports
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• v.53 no.12
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• pp.658-663
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• 2020

The N-myc downstream regulated gene (NDRG) family members are dysregulated in several tumors. Functionally, NDRGs play an important role in the malignant progression of cancer cells. However, little is known about the potential implications of NDRG4 in pancreatic ductal adenocarcinoma (PDAC). The aim of the current study was to elucidate the expression pattern of NDRG4 in PDAC and evaluate its potential cellular biological effects. Here, we firstly report that epigenetic-mediated silencing of NDRG4 promotes PDAC by regulating mitochondrial function. Data mining demonstrated that NDRG4 was significantly down-regulated in PDAC tissues and cells. PDAC patients with low NDRG4 expression showed poor prognosis. Epigenetic regulation by DNA methylation was closely associated with NDRG4 down-regulation. NDRG4 overexpression dramatically suppressed PDAC cell growth and metastasis. Further functional analysis demonstrated that up-regulated NDRG4 in SW1990 and Canpan1 cells resulted in attenuated mitochondrial function, including reduced ATP production, decreased mitochondrial membrane potential, and increased fragmented mitochondria. However, opposite results were obtained for HPNE cells with NDRG4 knockdown. These results indicate that hypermethylation-driven silencing of NDRG4 can promote PDAC by regulating mitochondrial function and that NDRG4 could be as a potential biomarker for PDAC patients.

• Journal of Technology Innovation
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• v.29 no.2
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• pp.31-57
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• 2021

So far, several researchers have studied the relationship between research and development investment and firm performance; however, most have focused on linear relationships. Thus, previous studies remain fragmented and show mixed results. This study examined the moderating effect of political ties in the relationship between R&D investment and firm performance. We tested the hypotheses based on extensive 20-year data on enterprises, from 1998 through 2017, as the research period. The study is expected to contribute to explaining the mixed results of the research between research and development investment and firm performance.