• KSBB Journal
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• v.25 no.2
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• pp.142-154
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• 2010

The protein-bound innerpolysaccharides (IPS) produced by suspended mycelial cultures of Inonotus obliquus have promising potentials as an effective antidiabetic as well as an immunostimulating agents. To enhance IPS production, intensive strain improvement process should be carried out using large amount of UV-mutated protoplasts. During the whole strain-screening process, the stage of solid growth-culture was found to be the most time-requiring step, thus preventing rapid screening of high-yielding producers. In order to reduce the cell growth period in the solid growth-stage, therefore, solid growth-medium was optimized using the statistical methods such as (i) Plackett-Burman and fractional factorial designs (FFD) for selecting positive medium components, and (ii) steepest ascent (SAM) and response surface (RSM) methods for determining optimum concentrations of the selected components. By adopting the medium composition recommended by the SAM experiment, significantly higher growth rate was obtained in the solid growth-cultures, as represented by about 41% larger diameter of the cell growth circle and higher mycelial density. Sequential optimization process performed using the RSM experiments finally recommended the medium composition as follows: glucose 25.61g/L, brown rice 12.53 g/L, soytone peptone 12.53 g/L, $MgSO_4$ 5.53 g/L, and agar 20 g/L. It should be noted that this composition was almost similar to the medium combinations determined by the SAM experiment, demonstrating that the SAM was very helpful in finding out the final optimum concentrations. Through the use of this optimized medium, the period for the solid growth-culture could be successfully reduced to about 8 days from the previous 15~20 days, thus enabling large and mass screening of high producers in a relatively short period.

• Radiation Oncology Journal
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• v.26 no.4
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• pp.280-288
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• 2008

Purpose: To identify the inter-fractional shift pattern and to assess an adequate treatment margin in the radiotherapy of a liver tumor using mega-voltage computed tomography (MVCT) of a tomotherapy unit. Materials and Methods: Twenty-six patients were treated for liver tumors by tomotherapy from April 2006 to August 2007. The MVCT images of each patient were analyzed from the $1^{st}$ to the $10^{th}$ fraction for the assessment of the daily liver shift by four groups based on Couinard's proposal. Daily setup errors were corrected by bony landmarks as a prerequisite. Subsequently, the anterior-, posterior-, right-, and left shifts of the liver edges were measured by maximum linear discrepancies between the kilo-voltage computed tomography (KVCT) image and MVCT image. All data were set in the 2-dimensional right angle coordinate system of the transverse section of each patient's body. Results: The liver boundary shift had different patterns for each group. In group II (segment 2, 3, and 4), the anterior mean shift was $2.80{\pm}1.73\;mm$ outwards, while the left mean shift was $2.23{\pm}1.37\;mm$ inwards. In group IV (segment 7 and 8), the anterior-, posterior-, right-, and left mean shifts were $0.15{\pm}3.93\;mm$ inwards, $3.15{\pm}6.58\;mm$ inwards, $0.60{\pm}3.58\;mm$ inwards, and $4.50{\pm}5.35\;mm$ inwards, respectively. The reduced volume in group II after MVCT reassessment might be a consequence of stomach toxicity. Conclusion: Inter-fractional liver shifts of each group based on Couinard's proposal were somewhat systematic despite certain variations observed in each patient. The geometrical deformation of the liver by respiratory movement can cause shrinkage in the left margins of liver. We recommend a more sophisticated approach in free-breathing mode when irradiating the left lobe of liver in order to avoid stomach toxicity.

• Korean Journal of Soil Science and Fertilizer
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• v.16 no.3
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• pp.266-273
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• 1983

In a series of studies on the chemical compositions and properties of organic matter from peats, volcanic ash soils and paddy rice soils, a comparative study on the composition and the fractional distribution of nitrogenous organic matters were undertaken for the elucidation on their characteristics. The results obtained are summerized as follows. 1. Gimpo and Peongtaeg peats showed higher content of organic matter, more than 60%, than Gimje and Yeongdong peats, and there is a great difference between the two groups in total-N, CEC and ash content. 2. The content of Lignin, Hollocellulose and Hemicellulose in organic matter was 12-25%, 15-31% and 7-14% respectively, and Gimpo peats were lots of Lignin content compared to others. 3. Sixty seven to eighty eight percent of the total-N in the soil was hydrolysable by 6 N-HCl and they were decreased in the order of volcanic ash soils (86.4%), mineral paddy soils (77.2%) and peats (72.3%). 4. The fractionations of acid hydrolysable organic-N were ${\alpha}$-amino acid-N(25-45%), unidentified-N (12-50%), amino sugar-N (1-7%) and ammonium-N (12-25%). 5. Almost same pattern in the amino acid composition of the acid hydrolysates of peat and soil organic matter was showed in the thin-layer chromatogram.

• Journal of IKEEE
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• v.12 no.4
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• pp.225-233
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• 2008

This paper presents a compact, low insertion loss, sharp rejection and wide band microstrip band pass filter that is composed rectangular loop resonator and step-impedance-open-stub(SIOS) for wireless data communication. The SIOS can be reduce length about 30% more than general 0.25${\lambda}$ stub. And stubs can have the advantage of tuning impedance magnitude. In order to demonstrate agrement of this paper prove, the optimized wide band pass filters are realized and experimented. A transmission line model used to calculate the frequency response of the new filters shows good agreement with measurements. The filter with perturbation stubs has four poles at rejection band, the poles are excited 3.610GHz, 4.265GHz at low frequency band, 8.494GHz, 9.056GHz at high frequency band. And the filter has 3dB fractional bandwidth of 57%(3.695GHz), an insertion loss of better than 0.37dB from 4.549GHz to 8.244GHz, and two rejection of greater than 30dB within 237MHz(4.312GHz${\sim}$ 4.549GHz) at low frequency band, 234MHz(8.244GHz-8.491GHz) at high frequency band.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.20 no.2
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• pp.200-207
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• 2009

This paper presents a compact, low insertion loss, sharp rejection and wide band microstrip band pass filter that is composed rectangular loop resonator and Step-Impedance-Open-Stub(SIOS). The SIOS can be reduce length about 30 % more than general 0.25 $\lambda$ open stub. And the stub can the advantage of tuning impedance magnitude. In order to demonstrate agrement of this paper prove, the optimized wide band pass filters are realized and experimented. A transmission line model used to calculate the frequency response of the new filters shows good agreement with measurements. The filter has 3 dB fractional bandwidth of 51.75 %(3.206 GHz), an insertion loss of better than 0.44 dB from 4.587 GHz to 7.793 GHz, and two rejection of greater than 30 dB within 221 MHz($4.326{\sim}4.587\;GHz$) at low frequency band, 181 MHz($7.739{\sim}7.954\;GHz$) at high frequency band. Maximum rejection characteristics of the filter are -61.8 dB at low frequency and -76.3 dB at high frequency.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.21 no.1
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• pp.28-35
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• 2010

In this paper, we designed and fabricated a ultra-wideband(UWB) bandpass filter with a good performance of a stopband, and a notched band in passband. The transformed equivalent circuit of the highpass filter was realized by distributed element. A wide-passband with 3-dB fractional bandwidth of more than 100 % was achieved by using optimum response of the HPF. For improving lower and upper stopband characteristic, a cross coupling between feed lines was employed, which was analyzed by desegmentation technique. In order to reject interference of Wireless LAN and Hyper LAN(5.15~5.825 GHz), the narrow notched(rejection) band was realized by a spurline. The fabricated BPF indicated the passband from 3.1 to 10.55 GHz and the flat group delay of less than 0.94 ns over the entire passband except the rejection band. The filter shown sharp attenuation both inside and outside the band and notched band from 5.2 to 6.12 GHz.

• Journal of Society of Preventive Korean Medicine
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• v.17 no.2
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• pp.47-68
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• 2013

Objectives : This research aimed to develop a new etiologic classification for traditional Korean Medicine in order to respond to the social and environmental change. Methods : We reviewed the existing theories on etiological classification for East Asian Medicine thoroughly and discussed the problems and limitations. Based on the experts' consensus, we abstracted disease factors and etiologic items. Results : The disease factors are classified into three parts: the human body, the environment, and the interaction between the human body and the environment. We defined them as the inner factor, the external factor, and the interaction between the inner and the external factors. The inner factor is free from the influence of the environment, and it causes diseases solely from the components of the human body. It is divided into genetic factors. The external factor is defined as a case when a disease occurs due to a factor outside the human body and includes external injuries, environmental pollution, and natural disasters. The interaction between the inner and the external factors is a disease factor that causes diseases by the interaction of the human body and the environment and includes emotions, habits, and social environment. As a result of the analysis, it was possible to see the meanings at a single glance as the scattered and fractional meanings were integrated with focus on medicinal herbs, but the increasing number of analyzed medicinal herbs tended to more and more complicate their relationships, thus, requiring additional work like filtering. Conclusions : The new etiologic classification of Korean Medicine fully reflects the perspectives on life in Korean Medicine while embracing the changes in modem society. Also, by avoiding the usage of ambivalent terms and wrong classification methods, the new classification system constructs intuitive and concise etiology and improves usability in clinical medicine.

• Korean Journal of Food Science and Technology
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• v.23 no.1
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• pp.88-92
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• 1991

To analyze the effects of the system parameters on the target parameters, which include the amount of water evaporation, water solubility index(WSI) and water absorption index(WAI), test trials of fractional factorial design of the three process variables at three levels were carried out for corn grit with a laboratory twin-screw extruder with three different screw configurations. The system parameters collected from the trials, such as extrusion temperature, specific mechanical energy input(SME) and mean residence time(RT), were showed the ranges of $129{\sim}182^{\circ}C$, $67{\sim}163\;kwh/ton$ and $12{\sim}34\;sec$, respectively. Within these ranges of the system parameters, the target parameters were able to be quantified by using multiple regression equations. The correlation of results with the system parameters blocked by the screw configuration as dependent variables, yield correlation coefficients above 0.90, and the correlation using the system parameters obtained from whole experiment system as the dependent variables yield correlation coefficients around 0.80. The functional relationship, which can be quantified by second order polynomial regression equation with only two system parameters within necessary degree of accuracy, can he graped in three dimensional surface response and contour diagrams.

• Journal of Korean Society for Atmospheric Environment
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• v.33 no.5
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• pp.497-514
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• 2017

This study quantitatively analyzes the effects of emission inventory choices on the simulated particulate matter (PM) concentrations and the domestic/foreign contributions in the Seoul Metropolitan Area (SMA) with an air quality forecasting system. The forecasting system is composed of Weather Research and Forecasting (WRF)-Sparse Matrix Operator Kernel Emissions (SMOKE)-Community Multi-Scale Air Quality (CMAQ). Different domestic and foreign emission inventories were selectively adopted to set up four sets of emissions inputs for air quality simulations in this study. All modeling cases showed that model performance statistics satisfied the criteria levels (correlation coefficient >0.7, fractional error <50%) suggested by previous studies. Notwithstanding the apparently good model performance of total PM concentrations by all emission cases, annual average concentrations of simulated total PM concentrations varied up to $20{\mu}g/m^3$ (160%) depending on the combination of emission inventories. In detail, the difference in simulated annual average concentrations of the primary PM coarse (PMC) was up to $25.2{\mu}g/m^3$ (6.5 times) compared with other cases. Furthermore, model performance analyses on PM species showed that the difference in the simulated primary PMC led to gross model overestimation in general, which indicates that the primary PMC emissions need to be improved. The contribution analysis using model direct outputs indicated that the domestic contributions to the annual average PM concentrations in the SMA vary from 44% to 67%. To account for the uncertainty of the simulated concentration, the contribution correction factor method proposed by Bae et al. (2017) was applied, which resulted in converged contributions(from 48% to 57%). We believe this study shows that it is necessary to improve the simulated concentrations of PM components in order to enhance the accuracy of the forecasting model. It is deemed that these improvements will provide more accurate contribution results.

• Journal of the Korean earth science society
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• v.18 no.6
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• pp.480-492
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• 1997

In order to understand the processes involved in the petrogenesis and the differentiation of the primary magma spectrum, a petrological and geochemical properties were investigated for the Chonju and the Sunchang foliated granites, which are located in the southwestern part of the Okchon zone and extends up to the northwestern boundary of the Ryongnam massif as two subparallel batholiths. Major element analyses show that the Chonju and Sunchang foliated granites are classified petrologically into a weakly to strongly peraluminous or calc-alkaline, but do not fit neatly into either of the I/S-type or magnetite/ilmenite-series classification schemes for granites, although the I-type and magnetite-series characteristics seem to be predominant based on the major element chemistry. In normative compositions, the Chonju granite is petrographically evolved from granodiorite to granite, whereas the Sunchang granite is from granodiorite to quartz monzodiorite. It seems to suggest a difference of the magmatic evolution processes such as crustal assimilation and/or fractional crystallization in magma. The REE patterns of both batholiths show high similarity and strongly fractionated REE distributions which show high $(Ce/Yb)_N$ ratios and little or no Eu anomalies. These REE patterns correspond broadly to those seen in the pre-Cretaceous granitoids of Korea. Apparently, the evidences obtained from the bulk compositions strongly suggest that the two foliated granitoids were formed by partial meltings of a relatively restricted and similar, may be common, source material which contains a continental crust component having an igneous composition, and have undergone a similar magmatic differentiation processes.