• Title/Summary/Keyword: Forward model

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Effects of ${\beta}2-Adrenergic$ Receptor Polymorphism on Obesity (베타 2-아드레날린 수용체의 유전자 변이형이 비만도에 미치는 영향)

  • Kim, Kil-Soo;Oh, Hyun-Hee;Choi, Sun-Mi;Yang, Hyun-Sung;Bae, Jung-Hwan;Yoon, Yoo-Sik
    • Journal of Korean Medicine for Obesity Research
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    • v.3 no.1
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    • pp.7-16
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    • 2003
  • Objectives : The lipolytic effects of catecholamines in adipose tissue are mediated by members of adrenergic receptors. This study was conducted to examine the effects of ${\beta}2-AR$ Gln27Glu (Q27E) polymorphism on obesity indices and risk among obesity clinic patients. Methods : 532 subjects, 38 men and 494 women, who attended a weight loss program in a local obesity clinic were analyzed. Height, weight, BMI, WHR and obesity index were measured or calculated. Body composition was measured by bio-impedance analysis. Genotype of ${\beta}2-AR$ polymorphism in codon 27 was analyzed by PCR-RFLP method. Serum concentrations of fasting glucose, total and HDL cholesterol, and triglyceride were determined by autobiochemical analyzer. Results: The Genotype distributions of ${\beta}2-AR$ gene were QQ type 81.3%, QE type 17.9% and EE type 8%. Therefore, the frequency of E allele of ${\beta}2-AR$ gene was 0.170 in the total subjects. The frequency of the ${\beta}2-AR$ variant genotype(QE+EE) was significantly higher in obese group($BMI{\geqq}25$) compared with non-obese group(p=0.027). Weight was significantly higher in variant(QE+EE) type compared with normal(QQ) type in total subjects(p=0.001), male(p=0.022) and female(p=0.013). BMI, obesity index and WHR were also significantly higher in QE+EE type. Body fat man was significantly higher in QE+EE type in total subjects(p=0.005) and female(p=0.027). When forward stepwise regression analysis was used to create a model of risk predictors of obesity($BMI{\geqq}25$), QE+EE type of ${\beta}2-AR$ gene was found to be a significant risk factor for obesity (p=0.042, ORs 1.597). Conclusions: QE+EE genotype of ${\beta}2-AR$ was associated with increased obesity indices and might be a significant risk factor for obesity.

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Discussions on the Reconstruction of Visual Illusion in Dynamic Images - Take of Paul Sermon as an example (다이나믹 이미지 예술 중 착시의 재구성에 관한 연구 - 폴 셔먼의 을 중심으로)

  • GAO, XIAOYA;Paik, Joonki
    • Journal of the Korea Convergence Society
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    • v.12 no.10
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    • pp.189-201
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    • 2021
  • The art of dynamic images has experienced three development stages, including experimental films, recording art, and new media image. By introducing all kinds of new materials, new media to the art, and the art of dynamic images has created more freedom for art creation. With the development of digital information technology, dynamic image works have put forward an increasingly high requirement of visual art. The combination of dynamic images and visual illusion can give rise to different forms and expression methods, thus endowing artworks with more vigor. This paper provides an overview by sorting out the lineage and development of dynamic images in the background, as well as understanding the application and performance of contrasted visual illusion. Based on the understanding of the characteristics of visual illusion, we discuss the new characteristics of applying the theory of visual illusion to new media dynamic images in relation to the technical approach of dynamic images. Through the analysis of specific works of Telematic Vision, we search for its reasonable combination and find the appropriate technical means of implementation. We discuss how to use digital multimedia technology and spatial optical illusion to make the design more novel and impactful, and consider how the combination of digital dynamic image technology and visual illusion should be interpreted and applied.

Rotor Hub Vibration Reduction Analysis Applying Individual Blade Control (개별 블레이드 조종을 통한 로터 허브 진동 저감 해석)

  • Kim, Taejoo;Wie, Seong-Yong;Kim, Minwoo;Lee, Dong-geon
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.49 no.8
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    • pp.649-660
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    • 2021
  • Through analytical method based on S-76 model, the level of rotor hub vibration reduction was analyzed according to higher harmonic actuating by individual blade control. The higher harmonic actuating method for individual blades was divided into a method of generating an additional actuating force from the pitch-link in the rotating part and generating actuating force through the active trailing edge flap control of the blade. In the 100kts forward flight conditions, the hub load analysis was performed by changing the phase angle of 15 degree for the 2P/3P/4P/5P harmonic actuation for individual blades. Through the harmonic actuation results, the sensitivity of the rotor system according to the actuating conditions was analyzed, and the T-matrix representing the characteristics of the rotor system was derived based on this analysis result. And through this T-matrix, optimal higher harmonic actuating condition was derived to minimize hub vibration level for flight condition. In addition, the effect on the performance of the rotor system and the pitch-link load under minimum hub vibration condition, as well as the noise influence through the noise analysis were confirmed.

The Optimal Project Combination for Urban Regeneration New Deal Projects (도시재생 뉴딜사업의 최적 사업지구 선정조합에 관한 연구)

  • Park, Jae Ho;Geem, Zong Woo;Yu, Jung Suk
    • Korea Real Estate Review
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    • v.28 no.1
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    • pp.23-37
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    • 2018
  • The genetic algorithm (GA) and branch and bound (B&B) methods are the useful methods of searching the optimal project combination (combinatorial optimization) to maximize the project effect considering the budget constraint and the balance of regional development with regard to the Urban Regeneration New Deal policy, the core real estate policy of the Moon Jae-in government. The Ministry of Land, Infrastructure, and Transport (MOLIT) will choose 13 central-city-area-type projects, 2 economic-base-type projects, and 10 public-company-proposal-type projects among the numerous projects from 16 local governments while each government can apply only 4 projects, respectively, for the 2017 Urban Regeneration New Deal project. If MOLIT selects only those projects with a project effect maximization purpose, there will be unselected regions, which will harm the balance of regional development. For this reason, an optimization model is proposed herein, and a combinatorial optimization method using the GA and B&B methods should be sought to satisfy the various constraints with the object function. Going forward, it is expected that both these methods will present rational decision-making criteria if the central government allocates a special-purpose-limited budget to many local governments.

Validation of the Measure of Health Literacy for the Elderly (고령자의 건강정보이해능력(Health Literacy) 측정도구 타당화)

  • Chun, Heeran;Cho, Sung-il;Kim, Il-Ho
    • Korean Public Health Research
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    • v.44 no.4
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    • pp.99-109
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    • 2018
  • Objective : Health literacy (HL) is, defined as "the degree to which individuals have the capacity to obtain, process, and understand basic health information and services needed to make appropriate health decisions." Being old is one of the main risk factors with limited health literacy. This study aims to adapt Chew's health literacy scale into the Korean language and validate the scale for the use of the elderly. Methods : Data were drawn from the '2016 Seoul Survey on Elderly Health and Functional Assessment, which includes a total of 725 people aged 60 to 79. The sample was randomly divided into two groups for reliability and validity tests of the modified Chew's scale of 8 items. The Korean version of the questionnaire was developed by group translation, expert reviews, and forward-backward translation. Exploratory and confirmatory factor analyses were conducted to assess and validate the factor structure of the scale. Results : Results suggest the two-factor structure ("Understanding" and "Applying" of HL) with 8 items. Exploratory factor analyses of the first sample (n=400) revealed that the internal reliability of the scale was high (Cronbach's ${\alpha}=.904$). Principal axis factoring extracted two factors ("Understanding" and "Applying" of HL) and explained 78.3% of total variance (KMO=.872, Bartlett's ${\chi}^2=2431.3$, df=28, p<.001). Confirmatory factor analysis of the second sample (n=325) was performed and the two-factor model was supported (GFI=.960, CFI=.979, TLI=.969, RMSEA=0.075). Conclusions : This study provides evidence for adequate criterion and validity of the health literacy scale for the community dwelling elderly in Korea.

Korea Service Insensity and Economic Growth in Korea Economy (한국 경제의 서비스화와 생산성: 중간재 생산자 서비스와 비생산자 서비스의 비교를 중심으로)

  • Seok, Jun-Ho;Kim, Soo-Eun;Kim, Chul
    • International Area Studies Review
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    • v.15 no.2
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    • pp.125-150
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    • 2011
  • As the economy grows, there is a concern that the economic development causes a productivity reduction because of the service intensive growth. However, the economy of developed countries encounter with the productivity growth as their economy grows, which phenomenon called Baumol's paradox. Oulton (1999, 2001) find out the reason of Baumol's paradox in a forward and backward chain effects. So, this paper is aimed at verifying the theory of Oulton (1999, 2001). Moreover, we test the difference effect between a consumer service and producer service input using a dummy variable. We use the Input-Output Table (1990, 1995, 2000, 2005) that is offered by the Bank of Korea to accomplish the purpose of our research that is represented above. We find out that the Korea's intermediate producer service inputs cause a multifactor productivity growth. That result is matched with the Oulton (1999, 2001)'s theory. But, the intermediate consumer service inputs don't have a significant effect on a multifactor productivity. The result of verifying the effect of intermediate producer service inputs among industries shows that the effects on manufacture industries are less than other industries.

A Phenomenological Study on Psychological Experiences and Resilience of Incest Sexual Victims in Adolescence (아동·청소년기 근친 성폭력 피해자의 심리경험과 적응에 관한 현상학 연구)

  • Chun, Hae-Lee;Shin, Dong-yeol
    • Industry Promotion Research
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    • v.6 no.2
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    • pp.37-46
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    • 2021
  • The purpose of this study is to examine the necessity of providing new perspectives by conveying the various psychological changes and realities experienced by victims of incest sexual violence after the incident, And it is meaningful to understand and record it through. The results of the analysis through the phenomenological methodology are as follows: First, participants were disturbed by the emotional neglect of their parents and forced violence, threats, and silence by their family members, resulting in disbelief in interpersonal relationships and low self-esteem and suffered constant difficulties in daily life. Second, the suffering and aftereffects of sexual violence experienced the conflict of roles by repeating the real maladjustment and social activity avoidance as the fear of being informed about the event, the negative thought about oneself, and the difficulty of interpersonal relationship. Third, the aftereffects of incest sexual violence in childhood·adolescence were found to be extreme with regard to PTSD. The PTSD experience has become a factor that forces participants to rely on substances, such as psychiatric medications and alcohol, and further avoids external activities with hallucinations and delusions. Fourth, the change through the adaptation process is a new perspective on life, facing and separating the events. During the adaptation program, they tried to express their words and feelings that they could not express because of the past hurts, to set goals for living their life, and to move forward. The experience of overcoming reality has enhanced participants' confidence in self-esteem, self-efficacy, and healthy self-control ability. In this study, it is meaningful to suggest a model in which the incest sexual violence trauma is reexperienced through the new daily crisis and the new adaptation process is repeated for each process.

Arts Organization's Business Diversification Strategies: Case of Sanwoollim Theater Company (예술단체의 사업다각화 연구 - 산울림 소극장의 사례를 중심으로 -)

  • Song, JuYoung;Chang, WoongJo
    • Korean Association of Arts Management
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    • no.53
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    • pp.153-177
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    • 2020
  • Arts organizations commonly face a range of operational challenges, from a lack of skilled workers to limited financial resources and thus are dependent on subsidies from the government. Yet, to fully realize their mission arts organizations must both develop strategies to effectively utilize government support and seek a way forward that does not depend on public subsidies. Business diversification, a strategy from corporate management, entails the expansion of products and services, and entry into new industries, enabling companies to disperse risks and increase profits. We propose that business diversification can be effectively applied to arts organization to address the myriad operational difficulties they face. To understand how an arts organization might deploy business diversification we conducted a case study of an organization that is actively pursuing the strategy: Sanwoollim Theater. We interviewed staff members of Sanwoollim including the executive director, as well as selected audiences, to understand how the business diversification model was being applied at Sanwoollim. Our findings indicate that, in a complex arts and cultural space, business diversification is a fresh and flexible new strategy that can enable private cultural arts organizations to thrive sustainably. It is also evident that government support in the initial stages of the process encourages diversification and that successful private arts organizations will leverage government subsidies into a sustainable business plan.

Estimation of the Source Adult Population for Agrotis ipsilon (Lepidoptera: Noctuidae) Appearing in Early Spring in Korea: An Approach with Phenology Modeling (국내에서 이른 봄 출현하는 검거세미밤나방 성충집단의 기원 추정: 페놀로지 모형을 통한 접근)

  • Sori Choi;Jinwoo Heo;Subin Kim;Myeongeun Jwa;Yonggyun Shin;Dong-Soon Kim
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.25 no.1
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    • pp.37-47
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    • 2023
  • The black cutworm, Agrotis ipsilon (Hufnagel), is an important crop pest worldwide that feeds more than 80 plant species including cabbage, potato, maize, wheat and bean, and this moth is a typical pest attacking underground parts of crops. It has been known in farm booklets that the larvae of A. ipsilon overwinter in the soil in Korea, but no definitive data exist yet. This study was conducted to evaluate that the specific appearance time of A. ipsilon observed actually in the field could be explained when we assumed that this pest overwinters in a form of larvae or pupae. Degree day-based phenology models were applied for tracking forward or backward to find the predicted developmental stage which developed at a specific stage found in the field. As a result of the analysis, it was confirmed that an initial population could be established in a group that does not overwinter as larvae or pupae in Korea. In other words, the appearance of adults in early March to April could not be explained by the presence of domestic overwintering populations. Populations that overwinter as larvae or pupae in Korea were able to emerge as adults in June to July at the earliest. Therefore, the group of adults appearing in early spring is highly likely to be a population that migrated from outside Korea. Taken together, it was estimated that the colony of A. ipsilon in Korea would be formed by a mixture of a migrant population through long-distance migration and a overwintering population.

The Impact of The User's Social Characteristics of 5G Services on The Intention of Use (중국 5G 서비스의 사용자 사회적 특성이 사용의도에 미치는 영향)

  • Nie, Xin-Yu;Qing, Cheng-lin
    • Journal of Digital Convergence
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    • v.20 no.3
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    • pp.63-68
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    • 2022
  • This After the debut of 5G, our lives have changed a lot. In particular, the proliferation of wireless network services through smartphones and LTE has completely changed the existing mobile communication services that are limited to voice/text communication between individuals and individuals, and new innovative services have emerged in all aspects of personal and corporate activities. This study verified the relationship between the social characteristics of 5G services and users' willingness to use 5G services. It analyzed the influence relationship between independent variables (social reality, subjective norms), media variables (perceived usefulness) and dependent variables (use intention), set hypotheses, and identified the media effects of perceived usefulness. The measurement items of variables are defined, and the research model of 5G service usage intention is designed. A questionnaire survey was conducted on the measurement items for users who have experience in using 5G services. Based on this result, among the social factors of users of 5G services, social reality and subjective norms are suitable factors to improve users' intentions. And through this research we put forward the enlightenment, discussed the limitations of the research and future research directions.