• 제목/요약/키워드: Formulas

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Effect of Black Garlic and Herb Formulas on Lipid Profiles and Antioxidant Status in Rats by Interval Running Training (간헐적 운동부하에서 흑마늘과 생약재의 복합처방이 흰쥐의 체내 지질 성분 및 항산화에 미치는 영향)

  • Lee, Soo Jung;Kim, In Sung;Lee, Hye Jin;Oh, Soo Jeong;Shin, Jung Hye;Kim, Jeong Gyun;Sung, Nak Ju
    • Journal of Life Science
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    • v.23 no.12
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    • pp.1436-1444
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    • 2013
  • To improve the functionality of black garlic drinks, black garlic extract (5%) and five herb extracts (1%) were mixed in 70:30 (v/v) ratios as BHF1, and BHF2 was prepared using a 3X concentration of BHF1. After the black garlic and herb formulas (BHFs) were administered over the course of five weeks in rats by interval running training, the lipid profiles and the antioxidant enzyme activities were tested. The total phenolic content of the BHFs were significantly higher in BHF2 than they were in BHF1, and their antioxidant activities were dependent upon the total phenolic content. No significant difference was found in the total serum protein levels among the rats in the Ex-con group by interval running training and the rats in the BHFs-fed groups. However, the albumin level was significantly higher in the Ex-BHF2 to Ex-con group. AST and ALT activities significantly decreased in the BHFs-fed groups compared to the Ex-con group. In terms of changes in the serum lipid profiles, no significant difference was found between the specimens that underwent interval running training and those that did not undergo interval running training. Triglyceride levels, total cholesterol, LDL-C, and HTR levels in the serum were significantly decreased in the Ex-BHF2 to Ex-con group. No significant difference was found in the total lipid levels in the livers of the BHFs-fed groups and the Ex-con group. The triglyceride levels and total cholesterol levels in the Ex-BHF2 group were significantly lower compared to another group. Hepatic catalase activity was significantly increased in the Ex-BHF2 group, but SOD and GSH-px activities were significantly increased as the concentration of the BHF. The antioxidant enzyme activities by supplementation of BHFs increased; thus, three intakes of BHF each day could improve antioxidant status against different types of oxidative stress.

A Study on the Development of a Microbial Insecticide -(With special emphasis on formulation)- (미생물(微生物) 살충제(殺蟲劑)의 개발(開發)에 관(關)한 연구(硏究) -(제제화(製劑化)를 중심(中心)으로)-)

  • Lee, Jae-Koo;Kim, Ki-Cheol;Kim, Do-Young
    • Applied Biological Chemistry
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    • v.22 no.2
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    • pp.123-134
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    • 1979
  • For the purpose of developing a microbial insecticide utilizing Bacillus thuringiensis Berliner, research was done and the following results were obtained. 1) As the freeze-dried matter of the cocoon-cooked water discarded from the filature contains much crude protein(51.825%) and a lot of inorganic salts, it can make a good nutrition source for the culture cf B. thuringiensis Berliner. 2) Based on the suspensibility, formula F-5 turned out to be the most suitable for insecticidal use. Its composition includes 0.2 g of the cell-spore-crystal mixture, 25 g of 200-mesh kaolin, 2.5 g of New Kalgen-NX-150, and 2.5 g of glycerine admixed with 8 ml of distilled water and granulated in 80-mesh size. 3) All the components of F-5, F-6 and F-7 are identical except that the amounts of cell-spore-crystal mixture of F-5, F-6, and F-7 are 0.2 g, 0.4 g, and 0.6 g, respectively. Accordingly, their physical properties are almost all the same. 4) Formulas F-5, F-6, and F-7 exhibited an excellent toxicity to Anomis mesogona Walker, Dendrolimus spectabilis Butler, and Margaronia perspectalis Walker at the concentration of 5%. 5) Formulas F-8 and F-9 which contain $NaHCO_3$ as one of their components showed a remarkably reduced toxicity to Anomis mesogona Walker and Dendrolimus spectabilis Butler than F-6 which does not contain $NaHCO_3$. 6) A maximum of $2.97{\times}10^9$ spores per ml was obtained by incubating B. thuringiensis in M-3 which has a pH of 7.05 and comprises 0.2% of ammonium sulphate and 0.8% of glucose dissolved in the cocoon-cooked water, with aeration for 96 hours. 7) Formula F-6 exhibited a somewhat reduced toxicity to Anomis mesogona Walker and Dendrolimus spectabilis Butler, when stored at room temperature for 70 days after formulation and it is desirable to keep it in a dark and cold place. 8) In held applications, formula F-6 showed a good activity in controlling Monema flavescens Walker. Margaronia perspectalis Walker, and Macrosiphum ibarae Matsumura.

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Studies on the Various Utilization of Microbial Formulation for the Production of Vegetable Crops (원예작물(園藝作物) 생산성(生産性)에 미치는 미생물(微生物) 제제(製劑)의 복합적(複合的) 이용연구(利用硏究))

  • Kim, Kwang-Sik;Kim, Young-Woong;Choi, Young-Soo
    • Korean Journal of Soil Science and Fertilizer
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    • v.28 no.2
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    • pp.191-205
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    • 1995
  • The carrier materials used for the development of bacterial inoculants to be effective in field were made with various carrier materials of two major forms, alginate bead and powder inoculants. Inoculants were prepared after mixing those carrier materials with Pseudomonas fluorescens SSL3 and Bacillus subtilis B5, and the treatment effects of each inoculants was investigated on cucumber, tomato, pepper and potato. Survival density of SSL3 and B5 in various carrier materials for duration of storage and the bead inoculants were better than the powder. In the powders, survival rate increased in carrier materials treated 5% skimilk. The growth condition of microorganisms in carrier materials is good at powder. When they were preserved in the long period, contamination is problem. Scanning(200 to 600nm) of the P. fluorescens SSL3 supernatant in centrifuged MKB broth incubated for 48h had two main peaks, pyochelin(300nm) and pyoverdin(400nm). The potato yield in field experiments of spring, treated with bead formulas showed increase of 22~29% in whole potato breeds as compared with control, because the bead formulas degraded, and released the antibiotic microorganisms in slow and constant rate. In the pot experiment, there were significant difference in soil, wheatbran, and bead formed wheatbran.

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Growth Curve Estimation of Stand Volume by Major Species and Forest Type on Actual Forest in Korea (주요 수종 및 임상별 현실림의 재적생장량 곡선 추정)

  • Yoon, Jun-Hyuck;Bae, Eun-Ji;Son, Yeong-Mo
    • Journal of Korean Society of Forest Science
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    • v.110 no.4
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    • pp.648-657
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    • 2021
  • This study was conducted to estimate the volume growth by forest type and major species using the national forest resource inventory and to predict the final age of maturity by deriving the mean annual increment (MAI) and the current annual increment (CAI). We estimated the volume growth using the Chapman-Richards model. In the volume estimation equations by forest type, coniferous forests exhibited the highest growth. According to the estimation formula for each major species, Larix kaempferi will grow the highest among coniferous tree species and Quercus mongolica among broad-leaved tree species. And these estimation formulas showed that the fitness index was generally low, such as 0.32 for L. kaempferi and 0.21 for Quercus variabilis. In the analysis of residual amount, which indicates the applicability of the volume estimation formula, the estimates of the estimation formula tended to be underestimated in about 30 years or more, but most of the residuals were evenly distributed around zero. Therefore, these estimation formulas have no difficulty estimating the volume of actual forest species in Korea. The maximum age attained by calculating MAI was 34 years for P. densiflora, 35 years for L. kaempferi, and 31 years for P. rigida among coniferous tree species. In broad-leaved tree species, we discovered that the maximum age was 32 years for Q. variabilis, 30 years for Q. acutissima, and 29 years for Q. mongolica. We calculated MAI and CAI to detect the point at which these two curves intersected. This point was defined by the maximum volume harvesting age. These results revealed no significant difference between the current standard cutting age in public and private forests recommended by the Korea Forest Service, supporting the reliability of forestry policy data.

Studies on the Durability of Mortars (모르타르의 내구성에 관한 연구)

  • 고재군
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.11 no.1
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    • pp.1604-1615
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    • 1969
  • This experiment was carried out as one of the basic studies to improve the acid resistance of concrete and it was conducted to investigate some relations among physical properties such as basorption, ratio of water to cement, compressive strength, density and ratio of mix to weight losses of mortar when exposed to 0.1 N solution of hydrochrolic acid. The results obtained from the limited data secured so far in this experiment are summarized as follows: 1. The specimens used in the experiment were made of 5 cubic centimeters of mortar having such various ratios of mix by weight as 1 : 1, 1 : 3, 1 : 5, 1 : 7, 1 : 10. 2. Physical tests included compressive strengths at 7 days, 28 days, 3 months, and 6 month, and 5 hour boiling absorption test. 3. In acid test, every specimen was immersed into 0.1 N solution of hydrochrolic acid. The specimens exposed to the acid solution were weighed to determine the weight losses of the acid-corroded at one week interval for 7 weeks exposure, and the old acid solutions were also changed to fresh one when weighed the weight losses by acid attack at one week interval. 4. The correlative relations were found among physical properties and they are expressed by certain formulas as follows; i) Relation between ratio of mix and absorption Y = 1.036x + 13.53 where Y: absorption(%) X: ratio of mix ii) Relation between ratio of mix and ratio of water-cement Y = 0.204x + 0.214 where Y: ratio of water-cement. X: ratio of mix iii) Relation between ratio of water-cement and absorption Y = 5.01x + 12.53 where Y: absorption(%). X: ratio of water-cement iv) Relation between density and absorption Y = 50.6 - 0.0176X where Y: absorption(%). X: density($kg/m^3$) v) Relation between density and ratio of water cement Y = 7.2183 - 0.0033X where Y: ratio of water-cement . X: density($kg/m^3$) 5. After completing the acid exposure test the specimens were corroded and , the per cent ranges of weight losses varies from a minimum of 20.4 per cent at a 1 : 1 mix to a maximum of 92.0 per cent at a 1:10 mix 6. The correlative relations of physical properties of mortar to weight losses by acid attak were found and they are also expressed by certain formulas as follows: i) Relation between weight losses and ratio of mix Y = 8.59X + 8.63 where Y: weight losses(%), X: ratio of mix ii) Relation between wieght losses and absorption Y = 0.121x + 12.43 where Y: absorption(%). X: weight losses(%) iii) Relation between weight losses and ratio of w/c Y = 0.0226X + 0.07 where Y: ratio of w/c X: weight losses(%) iv) Relation between weight losses and compressive strength LogY = 3.6097 - 0.05058X + 0.00022$X^2$ where Y: compressive strength ($kg/cm^3$) X: weight losses(%) v) Relation between weight losses and density Y = 2153.1 - 6.62X where Y: density($kg/m^3$) X: weigh losses(%) 7. In order to make better acid resistant mortar, it could be concluded that a 1 : 3 mix or richer mixes, adequate mixing water to minnimize the ratio of water-cement considering the workability, 16 per cent or less absorption by 5 hour boiling water, 1,800 kilogram per cubic meter or denser density by absolute weight base and 200 kilogram per square meter or compressive strength at 20 day, etc are required so as to obtain acid-resistant mortar. In addition to the above, it might be recommonded to select the fine aggregate and to use better equipments such as a mechanical vibrator, a mechanical mixer etc. in concrete manufacturing works.

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Comparative analysis of Glomerular Filtration Rate measurement and estimated glomerular filtration rate using 99mTc-DTPA in kidney transplant donors. (신장이식 공여자에서 99mTc-DTPA를 이용한 Glomerular Filtration Rate 측정과 추정사구체여과율의 비교분석)

  • Cheon, Jun Hong;Yoo, Nam Ho;Lee, Sun Ho
    • The Korean Journal of Nuclear Medicine Technology
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    • v.25 no.2
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    • pp.35-40
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    • 2021
  • Purpose Glomerular filtration rate(GFR) is an important indicator for the diagnosis, treatment, and follow-up of kidney disease and is also used by healthy individuals for drug use and evaluating kidney function in donors. The gold standard method of the GFR test is to measure by continuously injecting the inulin which is extrinsic marker, but it takes a long time and the test method is complicated. so, the method of measuring the serum concentration of creatinine is used. Estimated glomerular filtration rate (eGFR) is used instead. However, creatinine is known to be affected by age, gender, muscle mass, etc. eGFR formulas that are currently used include the Cockroft-Gault formula, the modification of diet in renal disease (MDRD) formula, and the chronic kidney disease epidemilogy collaboration (CKD-EPI) formula for adults. For children, the Schwartz formula is used. Measurement of GFR using 51Cr-EDTA (diethylenetriamine tetraacetic acid), 99mTc-DTPA (diethylenetriamine pentaacetic acid) can replace inulin and is currently in use. Therefore, We compared the GFR measured using 99mTc-DTPA with the eGFR using CKD-EPI formula. Materials and Methods For 200 kidney transplant donors who visited Asan medical center.(96 males, 104 females, 47.3 years ± 12.7 years old) GFR was measured using plasma(Two-plasma-sample-method, TPSM) obtained by intravenous administration of 99mTc-DTPA(0.5mCi, 18.5 MBq). eGFR was derived using CKD-EPI formula based on serum creatinine concentration. Results GFR average measured using 99mTc-DTPA for 200 kidney transplant donors is 97.27±19.46(ml/min/1.73m2), and the eGFR average value using the CKD-EPI formula is 96.84±17.74(ml/min/1.73m2), The concentration of serum creatinine is 0.84±0.39(mg/dL). Regression formula of 99mTc-DTPA GFR for serum creatinine-based eGFR was Y = 0.5073X + 48.186, and the correlation coefficient was 0.698 (P<0.01). Difference (%) was 1.52±18.28. Conclusion The correlation coefficient between the 99mTc-DTPA and the eGFR derived on serum creatinine concentration was confirmed to be moderate. This is estimated that eGFR is affected by external factors such as age, gender, and muscle mass and use of formulas made for kidney disease patients. By using 99mTc-DTPA, we can provide reliable GFR results, which is used for diagnosis, treatment and observation of kidney disease, and kidney evaluation of kidney transplant patients.

Longitudinal Changes in Calcium and Phosphorus Concentrations of Korean Human Milk (수유기간의 경과에 따른 한국인 인유의 칼슘 및 인 함량의 변화)

  • 윤태헌;태원찬;이정선
    • Journal of Nutrition and Health
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    • v.24 no.3
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    • pp.206-218
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    • 1991
  • The influence of stage of lactation on the moisture. total soilds, ash, calcium, phosphorus and Ca/P ratio of human milk was studied. A total number of 32 lactating mothers provided 101 samples collected at 4 consecutive stages of lactation : days o to 5 postpartum(colostrum); days 6 to 10 postpartum(transitional): days 25-35 postpartum(mature). and days 55-70 postpartum(mature). Moisture and total solids concentrations showed a little but significant difference at the 25-35 day stage as compared with those of colostrum and then remained stable, but ash levels decreased significantly with the elapse of lactation period. Calcium levels increased significantly from colostrum to transitional milk stage with a further less significant increase at mature stages. Between colostrum and transitional stages, phosphorus concentration showed a significant increase $(9.9\pm2.4$ vs $15.5\pm4.9$ mg/100 ml, p<0.001)but between the 25-35 day and the 55-70 day stage phosphorus values did not change significantly. Ca/P ratios for colostrum. transitional, the 25-35 day and the 55-70 day stages were 2.28, 1.76, 1.68 and 1.95, respectively. No significant relationship was found between ash. calcium, phosphorus or Ca/P ratio of milk and maternal parity. When modified milk formulas were reconstituted using the total solids of human mature milk as amount of the modified milk formula in 100 ml of infant feeding solution. ash, and Ca/P ratio were similar to those of human milk. However considerably higher concentrations of calcium and phosphorus exist in the reconstitution fluid than those observed in human milk.

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A Comparative Study for Effects of Chongmyungtang and Chocolate Mixed Chongmyungtang on Learning and Memory Impairment (총명탕과 초콜릿 첨가 총명탕의 학습 및 기억장애에 대한 효능 비교연구)

  • Kim, Seong-Joon;Park, Won-Sang;Choi, Hyeon;Kim, Bum-Hoi;Shin, Jung-Won;Sohn, Young-Joo;Sohn, Nak-Won;Jung, Hyuk-Sang
    • Herbal Formula Science
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    • v.16 no.1
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    • pp.131-145
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    • 2008
  • With tablets and powder, decoction has been a widely-used method of medicine formula. However, for these formulas have unique bitter tastes and flavors of herbal component materials as it is, the compliance of herbal medicine is severly decreased especially for female and younger patients. Consequently, expected treatment effects can't be acquired completely. If loathsome tastes and flavors of decoction were effectively reduced while pharmacological activity were kept intact, the compliance could be promoted Chong-Myung-Tang has been widely prescribed for student patients with memory This study shows that Chong-Myung-Tang+chocolate have no difference from Chong-Myung-Tang in terms of pharmacological activity. Sensory difference with net chocolate was also surved. In order to observe the difference of Chong-Myung-Tang+chocolate and Chong-Myung-Tang, memory impairment was induced by intraventricular injection of $A{\beta}_{25-35}$ peptides on mice and Chong-Myung-Tang and Chong-Myung-Tang+chocolate were administered orally for 14 days. In water maze task, improvement of learning ability during acquisition period and significant increase of memory score during retention period resulted from the treatment of Chong-Myung-Tang and Chong-Myung-Tang+chocolate with respect to the $A{\beta}-injected$ control animals. Furthermore, the $A{\beta}_{25-35}$ toxicity on the hippocampus was assessed with immunohistochemistry (Bax, TUNEL), and differences in antioxidant activity was observed through TBARS and DPPH test. We employed sensory tests using chocolate flavor, herb flavor, and bitter taste & hardness as standards to show sensory differences with net chocolate. In this study, it is demonstrated that Chong-Myung-Tang+chocolate do not disturb the pharmacological activity of Chong-Myung-Tang, and have no sensory difference with net chocolate. Chong-Myung-Tang+chocolate can be used to enhance the compliance remarkably and thought of as an effective, functional formula to maximize expected treatment.

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Study of Nonstoichiometry and Physical Properties of the Mixed Valency $Sr_xEu_{1-x}FeO_{3-y}$ ($0.00{\leq}x{\leq}$1.00) System (혼합원자가 $Sr_xEu_{1-x}FeO_{3-y}$ ($0.00{\leq}x{\leq}$1.00)계의 비화학량론과 물성 연구)

  • Ji Young Min;Kwon Sun Roh;Chul Hyun Yo
    • Journal of the Korean Chemical Society
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    • v.38 no.12
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    • pp.873-879
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    • 1994
  • A series of samples of solid solutions in the $Sr_xEu_{1-x}FeO_{3-y}(0.00{\leq}x{\leq}1.00)$ system has been prepared at $1200^{\circ}C$ under an atmospheric air pressure. The structures of solid solutions are studied by X-ray diffraction, thermal, Mohr salt, and Mossbauer spectroscopic analyses. Their physical properties are also discussed with the electrical conductivities. X-ray diffraction data for the compositions of x = 0.00, 0.25, and 1.00 are assigned to the orthorhombic and the compositions of x = 0.50 and 0.75 to the cubic systems. The lattice volume reduced to cubic cell increases with the x value. The mole ratio of $Fe^{4+}$ iometric chemical formulas of the system are formulated from the x, $\tau$, and y values. The mixed valency state of Fe ions, the oxygen coordination, and covalent bond character are discussed with the Mossbauer spectroscopic data. The activation enegy of the electrical conductivities depends on the $\tau$ value in the temperature range of -$100^{\circ}C$ to $600\circC$ under the air pressure. The Mossbauer spectrum and electrical conductivity of the solid solutions are discussed with nonstoichiometric chemical compositions.

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Analysis of the Correlation between Geological Characteristics and Water Withdrawals in the Laterals of Radial Collector Well (방사형집수정의 수평집수관에서 지질특성과 취수량의 상관관계 분석)

  • Kim, Tae-Hyung;Jeong, Jae-Hoon;Kim, Min;OH, Se-Hyoung;Lee, Jae-Sung
    • The Journal of Engineering Geology
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    • v.24 no.2
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    • pp.201-215
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    • 2014
  • This study was performed to investigate the correlation between hydraulic conductivity and the flow rate of an aquifer, with the flow rate calculated from the laterals of the radial collector well using data obtained by the development project of riverbank filtration (Second Phase) in Changwon City. The hydraulic conductivity was empirically calculated from unconsolidated sediments collected from a sandy gravel layer along the middle-to-downstream sections of the Nakdong River. The Beyer equation produced the most suitable hydraulic conductivity from the various empirical formulas employed. The calculated hydraulic conductivity ranged from 0.083 to 0.264 cm/s, with an average value of 0.159 cm/s, suggesting that the aquifer in the study area possesses a high permeability with a good distribution of sandy gravel. The relationship between the calculated hydraulic conductivity in the aquifer and the entrance velocity into the screen, the flow rate was analyzed through the linear regression analysis. From the result of regression analysis, it showed that the hydraulic conductivity and the entrance velocity into the screen and the flow rate have a linear regression equation having about 72% of the high correlation. The result of verification in the measured data between each variable showed a high suitability from being consistent with the approximately 72% in the linear regression analysis. This study demonstrates that the groundwater flow rate can be estimated within the laterals of the radial collector well using a linear regression equation, if the hydraulic conductivity of the aquifer is known. This methodology could thus be applicable to other aquifers with hydraulic conductivity and permeability parameters similar to those in the present study area.