• Title/Summary/Keyword: Formation of Site

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A study on characteristics of composition method of inner foundation in stone stupa (석탑 기단부 적심구성방법에 대한 특성 고찰 - $7{\sim}8$세기 석탑 중 해체 수리한 석탑을 중심으로 -)

  • Chung, Hae-Doo;Jang, Suk-Ha
    • Journal of architectural history
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    • v.16 no.5
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    • pp.55-66
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    • 2007
  • Through analysing on construction cases of stupa built in A.D. 7,8th, I have researched about these : constructive methods of inner soil of stupa, spatial compositions, characteristics of structures, arrangements of inner soil and etc. And cases analysed are six ; Mireuksajiseoktap(stone pagoda of Mireuksa Temple site), Gameunsajisamcheumgseoktap(three storied stone pagoda of Gameunsa Temple site), Goseonsajisamcheungseoktap(three storied stone pagoda of Goseonsa Temple site), Wolseong nawolliocheungseoktap(five storied stone pagoda in Nawonri, Wolseong), Guksagokseoktap(three storied stone pagoda in Guksa valley), Giamgokseoktap(three storied stone pagoda in Giam valley). Additionally we researched about inner soil of Sacheonwangsaji tapji(basement of stone stupa site in Sacheonwang Temple site) to speculate on composition of Synthetically, the foundation could be divided as core space and outer space. ; the former as structural function and the latter as ornamental function. And the core area could be divided again as center column space and buffer space. The relationship between core spaces and its formation are as belows; First, according to the area of foundation and scale of stone pagoda, formations of core are differed. As the scale of stone pagoda goes bigger, and the area of foundation goes larger, the structure of stone pagoda comprised by center column type and layered-core which endure upper load independently. On the contrary, as the scale of stone pagoda goes smaller, and the area of foundation goes lesser, the structure of stone pagoda tend to use only center column to endure upper part. Second, spatial composition of core area is comprised as two spaces, one which endure upper load and buffer space which absorb side pressure and upper pressure. The buffer space tend to be used in case of those structures which could not endure side pressure or have lots of joint. In some cases, it was located below the cover stone of foundation and gained upper load. And in case that have not gained pressure from side stone, the buffer space are comprised by smalle stone or roof tile to get structural supplement.

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Suppression of AP-1 Activity by Tanshinone and Cancer Cell Growth Inhibition

  • 박세연;송지성;이덕근;양철학
    • Bulletin of the Korean Chemical Society
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    • v.20 no.8
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    • pp.925-928
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    • 1999
  • The process of transcription is the major point at which gene expression is regulated. The jun and fos families of eukaryotic transcription factor heterodimerize to form complexes capable of binding 5'-TGAGTCA-3'DNA elements (AP-1 binding site). To search for the inhibitors of the jun-fos-DNA complex formation, several natural products extracts were screened and methanol extract of tanshen (the dried roots of Salvia miltiorrhiza Bunge) showed remarkable inhibitory activity. The active compounds of the extracts were purified using re-peated column chromatography and recrystallization. Their structures were identified as tanshinone I and tanshinone IIA. Through the electrophoresis mobility shift assay and cell cytotoxicity test, tanshinone I and tanshinone IIA were identified as inhibitors that suppress not only AP-1 function but also the cell proliferation. Tanshinone I also suppressed the jun-fos-DNA complex formation in TPA-induced NIH 3T3 cells.

The Composting Techniques for On-site Recycling of Wood Waste (임목폐기물의 현장 재활용을 위한 퇴비화기술)

  • Hur, Young-Jin;Koh, Jeung-Hyun;Joo, Paik;Ahn, Tae-Young
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.12 no.4
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    • pp.72-80
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    • 2009
  • The main purpose of this study is as follows : Finding a solution for fresh wood chips to be used as an alternative growing-media through a study of the formation method of a compost base that is applicable on both construction site and composting factory to ferment fresh wood chips produced from construction site as well as a study on adjuvant or secondary materials. The result from the experiment plot using wood chips sized 50mm or less, manure and fertilizer mixed manure as a source of nitrogen to compost fresh wood chips has shown that the temperatures 9days and 3days after the beginning of the experiment reached to $49.0^{\circ}C$ and $40.4^{\circ}C$ respectively, the heating duration was 7days and 4days respectively, and the C/N ratio was 26.5 and 25.3, each satisfying the standard for composted manure (25.0~40.0). Also, the other result from another experiment plot using mixture of sandy soil and microorganism as an inoculation source of microorganism has shown that the temperature 10days after the beginning of the experiment reached to $67.6^{\circ}C$ and lasted 16days. The experiment plot using sandy soil has shown the highest figure of $5.3{\sim}108$ CFU/g in terms of number of microorganism. The result from the experiment plots for on-site composting of fresh wood chips have shown that the experiment plot that used sandy soil with fertilizer due to supply restriction of manure as a nitrogen source in construction site reached the high temperature of $54.7^{\circ}C$ after 3days of experiment beginning and maintained heating state for 17days and reached 30.6 of C/N ratio, satisfying the standard for composted manure.

Hybrid Biomaterial of PLGA Microspheres and Hyaluronic Acid as a Potential Injectable Bulking Agent for Urologic and Dermatologic Applications

  • Cho, Eui-Ri;Kang, Sun-Woong;Kim, Byung-Soo
    • 한국생물공학회:학술대회논문집
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    • 2003.10a
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    • pp.644-647
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    • 2003
  • Materials currently used as an injectable bulking agent in the dermatologic and urologic fields revealed several drawbacks such as particles migration, inflammatory reaction, allergic reaction, rapid volume shrinkage, and necessity of a donor site. In this study, we have developed injectable biomaterial comprising poly (DL- lactide-co-glycolide)(PLGA) and hyaluronic acid gel to overcome these problems. PLGA is a biocompatible synthetic material and hyaluronic acid is a common substance found in living organisms. We examined the feasibility of injection through needle and tested biocompatibility in animal model. After transplantation, injected sites and distant organs were examined histologically to verify a new tissue formation, inflammation, and particles migrations. Injected volume was maintained approximately 80 percent for 2 months. Results demonstrated that the developed material was injectable through various gauges of needles and induced a new bulking tissue formation without serious inflammatory reaction.

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Swapping of interaction partners with ATG5 for autophagosome maturation

  • Kim, Jun Hoe;Song, Hyun Kyu
    • BMB Reports
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    • v.48 no.3
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    • pp.129-130
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    • 2015
  • Autophagy is a tightly regulated lysosome-mediated catabolic process in eukaryotes that maintains cellular homeostasis. A distinguishable feature of autophagy is the formation of double- membrane structures, autophagosome, which envelopes the intracellular cargoes and finally degrades them by fusion with lysosomes. So far, many structures of Atg proteins working on the autophagosome formation have been reported, however those involved in autophagosome maturation, a fusion with lysosome, are relatively unknown. One of the molecules in autophagosome maturation, TECPR1, has been identified and recently, structural studies on both ATG5-TECPR1 and ATG5-ATG16L1 complexes revealed that TECPR1 and ATG16L1 share the same binding site on ATG5. These results, in combination with supporting biochemical and cellular biological data, provide an insight into a model for swapping ATG5 partners for autophagosome maturation.

Managing Soil Organic Matter and Salinity by Crop Cultivation in Saemangeum Reclaimed Tidal Land

  • Bae, Hui Su;Jang, Hyeonsoo;Hwang, Jae Bok;Park, Tae Seon;Lee, Kyo Suk;Lee, Dong Sung;Chung, Doug Young
    • Korean Journal of Soil Science and Fertilizer
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    • v.51 no.1
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    • pp.50-60
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    • 2018
  • This study was to evaluate the effect of organic amendments incorporation on soil properties and plant growth under two different soil salinity levels and various cultivated crops at Saemangeum reclaimed tidal land for three years from 2012 to 2014. The soil texture of the experimental site was sandy loam. Four different crops, sesbania (Sesbania grandiflora), sorghum-sudangrass hybrid (Sorghum bicolor-Sorghum sudanense), rice (Oryza sativa L.) and barley (Hordeum vulgare) were cultivated at low (< $1dS\;m^{-1}$) and high (> $4dS\;m^{-1}$) soil salinity levels. The soil salinity was significantly lowered at the rice cultivation site compared to continuous upland crops cultivation site in high soil salinity level. But the soil salinity was increased as cultivating sesbania coutinuously in low soil salinity level. The soil organic matter content was increased with the incorporation of straw at the continuous site of rice and barley, and the average of soil organic matter was increased by $0.9g\;kg^{-1}$ per year which was effective in soil aggregate formation. The highest biomass yield plot was found in barley (high salinity level) and sesbania (low salinity level) cultivation site, respectively. Our research indicates that rice cultivation in paddy field with high salinity level was effective in lowering soil salinity and sesbania cultivation was useful to biomass production at upland with low salinity. In conclusion, soil salinity and organic matter content should be considered for multiple land use in newly reclaimed tidal land.

Crystal Structure of Fully Dehydrated Partially Cs+-Exchanged Zeolite X, Cs52Na40-X (The Highest Cs+-Exchanged Level Achieved by Conventional Method and Confirmation of Special Site Selectivity)

  • Bae, Myung-Nam
    • Bulletin of the Korean Chemical Society
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    • v.28 no.2
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    • pp.251-256
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    • 2007
  • The crystal structure of fully dehydrated partially Cs+-exchanged zeolite X, [Cs52Na40Si100Al92O384], a = 24.9765(10) A, has been determined by single-crystal X-ray diffraction techniques in the cubic space group Fd3 at 21 °C. The crystal was prepared by flow method for 5 days using exchange solution in which mole ratio of CsOH and CsNO3 was 1 : 1 with total concentration of 0.05 M. The crystal was then dehydrated at 400 °C and 2 × 10-6 Torr for 2 days. The structure was refined to the final error indices, R1 = 0.051 and wR2 (based on F2) = 0.094 with 247 reflections for which Fo > 4σ (Fo). In this structure, about fifty-two Cs+ ions per unit cell are located at six different crystallographic sites with special selectivity; about one Cs+ ion is located at site I, at the centers of double oxygen-rings (D6Rs), two Cs+ ions are located at site I', and six Cs+ ions are found at site II'. This is contrary to common view that Cs+ ions cannot pass sodalite cavities nor D6Rs because six-ring entrances are too small. Ring-opening by the formation of ?OH groups and ring-flexing make Cs+ ions at sites I, I', and II' enter six-oxygen rings. The defects of zeolite frameworks also give enough mobility to Cs+ ions to enter sodalite cavities and D6Rs. Another six Cs+ ions are found at site II, thirty-six are located at site III, and one is located at site III' in the supercage, respectively. Forty Na+ ions per unit cell are located at two different crystallographic sites; about fourteen are located at site I, the centers of D6Rs and twenty-six are also located at site II in the supercage. Cs+ ions and Na+ ions at site II are recessed ca. 0.34(1) A and 1.91(1) A into the supercage, respectively. In this work, the highest exchange level of Cs+ ions per unit cell was achieved in zeolite X by conventional aqueous solution methods and it was also shown that Cs+ ion could pass through the sixoxygen rings.

Formation of Cross-Linked Products of The Reaction Center D1 Protein in Photosystem II under Light Stress

  • Uchida, Suguru;Kato, Yoji;Yamamoto, Yasusi
    • Journal of Photoscience
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    • v.9 no.2
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    • pp.382-384
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    • 2002
  • When illuminated with strong visible light, the reaction center Dl protein of photo system II is photodamage and degraded. Reactive oxygen species and endogenous cationic radicals generated by photochemical reactions are the cause of the damage to the Dl protein. Recently we found that the photodamaged Dl protein cross-links with the surrounding polypeptides such as D2 and CP43 in photosystem II. As the cross-linking reaction is dependent on the presence of oxygen, reactive oxygen species are suggested to be involved. Among the reactive oxygen species examined, ? OH was most effective in the formation of the cross-linked products. These results indicate that the cross-linking is mostly due to ? OH generated at photosystem II. The cross-linking site of the Dl protein is not known. As several tyrosine residues exist at the D­E loop of the Dl protein, there is a possibility that di-Tyr is formed between the D­E loop of the Dl protein and surrounding polypeptides during the strong illumination. Therefore, we examined the formation of di-Tyr using the monoclonal antibody against di-Tyr under excess illumination of the photosystem II membranes. The results obtained here suggest that no di-Tyr is formed during the excess illumination of photosystem II.

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Periodontal healing following non-surgical repair of an old perforation with pocket formation and oral communication

  • Asgary, Saeed;Verma, Prashant;Nosrat, Ali
    • Restorative Dentistry and Endodontics
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    • v.43 no.2
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    • pp.17.1-17.7
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    • 2018
  • Iatrogenic perforations negatively impact the outcome of endodontic treatments. Studies on prognostic factors showed that perforations in the coronal third of the root with periodontal pocket formation have an unfavorable prognosis. A 36-year-old female was referred for endodontic evaluation of tooth #13 with a history of an iatrogenic perforation, happened 3 years ago. There was a sinus tract associated with perforation, 10 mm probing on the mesial and mesio-palatal, bleeding on probing, radiolucent lesion adjacent to the perforation and complete resorption of the interdental bone between teeth #13 and #12. After the treatment options were discussed, she chose to save the tooth. The tooth was accessed under rubber dam isolation, the perforation site was cleaned and disinfected using 0.5% sodium hypochlorite and sealed with calcium-enriched mixture cement. Eighteen months after treatment the tooth was functional and asymptomatic. The probing depths were normal without bleeding on probing. Radiographically, the interdental crestal bone formed between teeth #13 and #12. Despite all negative prognostic factors in this case (i.e., perforations in the coronal third, pocket formation, and radiolucent lesion), healing was unexpectedly achieved via non-surgical repair of the perforation. Further research on biological aspects of healing in the periodontium following iatrogenic perforations are recommended.

Electrostatic Charging and Substrate Seeding in Gas Phase Synthesis of Nanocrystalline Diamond Powder

  • Cho, Jung-Min;Lee, Hak-Joo;Choi, Heon-Jin;Lee, Wook-Seong
    • Proceedings of the Korean Vacuum Society Conference
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    • 2012.08a
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    • pp.418-418
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    • 2012
  • Synthesis of nanocrystalline diamond powder was investigated via a gas-to-particle scheme using the hot filament chemical vapor deposition. Effect of substrate surface seeding by nano diamond powder, and that of the electrical conductance of the substrate were studied. The substrate temperature, methane content in the precursor gas, filament-substrate distance and filament temperature were $670^{\circ}C$, 5% methane in hydrogen, 10 mm and $2400^{\circ}C$, respectively. The powder formation by gas-to-particle mechanism were greatly enhanced by the substrate seeding by the nano diamond powder. It was attributed to the removal of the electrostatic force between the substrate and the seeded nano diamond particle by the thermal electron shower from the hot filament, via the depolarization of the substrate surface or the attached diamond powder and subsequent levitation into the gas phase to serve as the gas-phase nucleation site. The powder formation was greatly favoured by the conducting substrate relative to the insulating substrate, which proved the actual effect of the electric static force in the powder formation.

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