• Archives of Pharmacal Research
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• v.22 no.6
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• pp.624-628
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• 1999

A formal asymmetric synthesis of Mugineic acid was accomplished from cis-2-butene-1,4-diol throughcatalytic Sharpless epoxidation oxidations and doupling reaction.

• YAKHAK HOEJI
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• v.57 no.5
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• pp.357-361
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• 2013

A formal synthesis of Lespedezol $A_1$ has been accomplished. The key feature of this synthesis involves an efficient and powerful palladium-catalyzed cross coupling reaction of diazocarbonyl compound with bis(benzyloxy)phenylboronic acid for the key 3-aryl-chromen-4-one intermediate, which was difficult to be prepared by Suzuki coupling reaction in the previous study. The versatile and efficient synthetic procedure would facilitate synthesis of pterocarpenes and their derivatives.

• Archives of Pharmacal Research
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• v.19 no.6
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• pp.581-585
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• 1996

A new formal total synthesis of (+)-6-oxo-3, 4, 4a, 5-tetrahydro-3-hydroxy-2, 2-dimenthylnaphtho-1, 2-pyran (1) which has been known to have bactericidal, bacteriostatic, fungicidal, fungistatic activities against Staphylococcus aureus and other microorganism, is described. The key reaction involves enantioselective prenylation of .alpha.-tetralone via chiral lithioenamine.

• Bulletin of the Korean Chemical Society
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• v.32 no.spc8
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• pp.3141-3144
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• 2011

• Bulletin of the Korean Chemical Society
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• v.32 no.1
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• pp.315-318
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• 2011

• Bulletin of the Korean Chemical Society
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• v.9 no.3
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• pp.135-136
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• 1988

Cleavage of exo-7-substituted-6,8-dioxabicyclo[3.2.1]octanes with acetyl iodide in the predominance of the trans alkene product. This bicyclic ketal fragmentation methodology is utilized to a formal synthesis of sirenin.

• Journal of the Korea Institute of Military Science and Technology
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• v.5 no.4
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• pp.49-56
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• 2002

For the purpose of the increase in the performance and thermal stability of PBX's, the mixed formal consisting of BDNPF, DNPBF and BDNBF were synthesized. In order to find out the optimal condition for the synthesis of energetic plasticizer, BDNPF, DNPBF and BDNBF, the synthetic procedures have been investigated. We synthesized DNP-OH and DNB-OH through oxidative nitration and controlled various composition of mixed formal by $H_{2}SO_{4}$ and s-trioxane to investigate optimal composition, and then characterized its thermo-physical properties.

• Bulletin of the Korean Chemical Society
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• v.34 no.12
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• pp.3777-3781
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• 2013

A formal total synthesis of aliskiren was accomplished. A key in our synthesis was to use the symmetric ciscisoid-cis-bis-lactone 3' as a precursor, which was prepared from D-tartrate diester. Appending the end groups and functional group transformations completed the synthesis.

• Bulletin of the Korean Chemical Society
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• v.34 no.1
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• pp.303-305
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• 2013

• Journal of the Korean Chemical Society
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• v.68 no.3
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• pp.131-134
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• 2024

A simple strategy for the formal synthesis of the sex pheromone of gypsy moth (+)-disparlure from L-(+)-tartaric acid is described herein. The key steps include the mono-esterification and regioselective ring-opening of an epoxide using a Grignard reagent. The strategy of conferring asymmetry using 2-butanone enables mono-esterification in high yield and reduces the number of steps. Subsequently, (+)-disparlure is synthesized via the regioselective ring opening of the epoxide.