• 대한의용생체공학회:의공학회지
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• 제28권5호
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• pp.647-656
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• 2007

The purpose of this study was to analyze the effects of vibratory stimulus as somatosensory inputs on the postural control in human standing. To study these effects, the center of pressure(COP) was observed while subjects were standing on a stable and an unstable support with co-stimulated mechanical vibrations to flexor ankle muscles(tibialis anterior tendon, achilles tendon) and two plantar zones on both foot. The COP sway measurement was repeated twice in four conditions: (1) with visual cue and vibration, (2) without visual cue and vibration, (3) with visual cue and without vibration, (4) without visual cue and with vibration. The calculated parameters were the COP sway area and the distance, the median frequency and the spectral energy of COP sway in three intervals $0.1{\sim}0.3,\;0.3{\sim}1,\;1{\sim}3Hz$. The results showed that vibratory stimulus affect postural stability. The reduction rate of the COP sway with vibratory stimulus were higher on the unstable support because the effect of postural stability increases when afferent nervous flow is more activated by vibration on unstable support. If unclear visual or vibratory information is received, one type of information is compared with the other type of sensory information. Then the input balance between visual and vibratory information is corrected to maintain postural stability. These findings are important for the rehabilitation system of postural balance control and the use of vibratory information.

• 대한미생물학회지
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• 제35권2호
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• pp.117-127
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• 2000

The non-ELR-containing CXC chemokines Mig and IP-10 have been shown to function as chemotactic cytokines for activated T lymphocytes. In this study, we examined the potential involvement of Mig and IP-10 in antimycobacterial response of mice immunized or infected with M. bovis BCG. The accumulation of Mig and IP-10 mRNA in resident peritoneal monocytes ($RPM{\Phi}$) was slightly reduced by stimulation with vBCG, and the degree was greater for 24 hr culture even though IFN-${\gamma}$ was added. Expression of Mig, IP-10, and IFN-${\gamma}$ in 24 hr delayed-type hypersensitivity (DTH) response was stronger in vBCG-immune mice than in the non-immune. The increase of DTH measured by foot-pad thickness appears to be clearly related to the levels of chemokines Mig and IP10 messages and those of IFN-${\gamma}$ and IL-12. Stimulation with vBCG for 2 days decreased or completely dropped the levels of Mig message in non-immune or immune splenocytes, respectively, whereas IP-10 message was slightly decreased in 2 days culture. Moreover, messages for IL-12 (p40) showed similar kinetics for Mig. The levels of Mig and IP-10 mRNA during the course of infection with BCG were not readily changed in lungs, livers, and spleens from BCG-infected mice. Although there was no obvious changes of Mig and IP-10 messages in the target organs during infection process, we found that the infection progressed over the first 3 wk before being contained by the emerging immune response suggested from detectable amount of IFN-${\gamma}$ mRNA around this time. In view of selectivity of chemokines Mig and IP-10 for activated T cells, these data suggest that chemokine Mig and IP-10, especially in collaboration with IL-12 and IFN-${\gamma}$, may playa role as T cell recruiters in immune response against mycobacterial infection.

• 한방안이비인후피부과학회지
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• 제15권1호
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• pp.343-355
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• 2002

Background : Although Samsoeum has been used frequently on allergic rhinitis, but there isn't any experimental research for that. Objective : This study was performed to investigate the anti-allergic effects of Samsoeum and Samsoeumgamibang. Materials and Methods : Katayama's method was used to observe the vascular permeability response induced by serotonin and histamine. Muller's method was used to observe the contact dermatitis response induced by picryl chloride. Miller's method was used to observe the delayed type hypersensitivity response to SRC. Results : 1. In the vascular permeability response to intradermal injection of serotonin, 2,600mg/kg, p.o. group of Samsoeum(蔘蘇飮), 1,300 and 2,600mg/kg, p.o. group of Samsoeumgamibang(蔘蘇飮加味方) showed significant inhibitory effects on the leakage of Evan's blue solution. 2. In the vascular permeability response to intradermal injection of histamine, 1,300 and 2,600mg/kg, p.o. group of Samsoeum, also 1,300 and 2,600mg/kg, p.o. group Samsoeumgamibang showed significant inhibitory effects on the leakage of Evan's blue solution. 3. In the contact dermatitis response induced by picryl chloride, 1,300 and 2,600mg/kg, p.o. group of Samsoeum, 1,300 and 2,600mg/kg, p.o. group of Samsoeumgamibang showed significant inhibitory effects on ear swelling formation. 4. In the delayed type hypersensitivity response to SRC. 2,600mg/kg, p.o. group of Samsoeum and 2,600mg/kg, p.o. group of Samsoeumgamibang showed significant inhibitory effects on foot swelling. Conclusion : This study shows that Samsoeum and Samsoeumgamibang may have anti-allergic effects. So Samsoeum and Samsoeurngamibang can be helpful to treat allergic rhinitis.

• 대한임상전기생리학회지
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• 제8권2호
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• pp.33-37
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• 2010

Purpose : We investigated the effects of the insole types on lower leg muscle activation during treadmill walking. The three insole types investigated for this study were normal insole, medial wedge insole, and viscoheel. Methods : Participants were assigned into three groups. People with foot transformation were excluded from this study. Each participant walked for ten minutes. The first day we applied a normal insole. On the second day, a medial wedge insole was applied. Finally, on the last day a viscoheel was applied. After walking on a treadmill for ten minutes, we measured muscle activation in lower leg muscles (gastrocnemius and tibialis anterior). Surface electromyography (EMG) was used to measure muscle activity. The data were analyzed using one-way analysis of variance (ANOVA) with repeated measures to determine the statistical significance. Results : The results of this study were summarized as follows. While walking on the treadmill, root mean square (RMS) values of the gastrocnemius when the viscoheel was applied were significantly lower than the other insole types. There was no significant difference for the RMS values for the tibialis anterior using viscoheel. The normal insole and viscoheel insole were significantly different in a post hoc analysis. However, there was no significant difference for normal insole and medial wedge insole. Conclusion : Using a viscoheel insole decreases muscle activity of the lower leg. Therefore, in conclusion, the viscoheel insole type reduces the load on the lower leg during walking.

• 한국의류산업학회지
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• 제22권4호
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• pp.407-412
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• 2020

This study investigated the technological development of Korean functional product design for posture correction. We analyzed registered and disclosed Korean patents (n=289) of KIPRIS. They were posture correction technology patents filed from 1999 to 2018. Keywords used in patent selection were posture correction, posture correction clothing, posture correction band, rehabilitation clothing, joint protection, protective equipment, and compression wear. These were then analyzed by patent application year, product type, effect pursued, and posture correction body part. The results showed that patent applications related to posture correction technology have increased since 2014. Products subject to patents for posture correction technology were device/brace (59.5%), footwear (22.5%), and clothing (18.0%). Patents for posture correction pursued various wearing effects. The effects pursued were dependent on the product type. The device/brace focused on joint protection (76.7%) and muscle reinforcement (40.7%). Footwear was focused on joint protection (90.8%). The clothes were focused on muscle reinforcement (50.0%) and body shaping (36.5%). The clothing and device/brace for posture correction were worn on various body parts of the upper limbs to feet. The posture correction product design patent was to correct various body parts. Patents pursuing upper body correction focused on spine posture correction (n=99). Patents for foot posture correction have steadily increased (n=102). Patents for posture correction of the pelvis and hip joints were relatively few (n=46). The results of this study implied the necessity to develop technology to correct posture by combining the functions of device/brace and clothing.

• Journal of Acupuncture Research
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• 제22권2호
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• pp.19-32
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• 2005

Objectives : to evaluate the analgesic effect of bee venom acupuncture on Choksamni (ST36) in the collagen-induced arthritis rats and investigate the role played by serotonergic receptor subtypes (5-HT1a, 5-HT2a) in the antinociceptive effect of bee venom acupuncture in a thermal hyperalgesia test Methods : Experiments were performed on 5 week-aged 60 male Sprague-Dawley rats according to National Institute of Health guidelines and the ethical guidelines of the International Association for the Study of Pain (IASP). Arthritis was induced with arthrogenic collagen emulsion (Bovine type II collagen ${\mu}g$ with incomplete Freund's adjuvant $100\;{\mu}g$). The onset of arthritis was considered to be present when erythema and swelling were detected in at least one joint. The thermal hyperalgesia was evaluated weekly with tail flick test in the rats of severity grade 3 without any injury at tail and foot (including inflammation, ulceration, snap). In the fourth week after first immunization, the analgesic effect of bee venom acupuncture (Choksamni, ST36) was measured with consecutive tail flick latency after intraperitoneal injection of spiroxatrine (1mg/kg) and spiperone (1mg/kg). Results : Chronic inflammatory pain was induced as time elapsed after the immunization of arthrogenic collagen and the maximum value was reached from third to fifth week. Chronic inflammatory pain induced by CIA was inhibited by bee venom acupuncture on the left ST36. The analgesic effect of bee venom acupuncture was inhibited by intraperitoneal injection of 5-HT1a antagonist spiroxatrine and 5-HT2a antagonist spiperone. Conclusions : Therefore, a conclusion. that the analgesic effect of bee venom acupuncture in the chronic inflammatory pain is partially mediated by 5-HT1a and 5-HT2a receptors can be made.

• 한국식생활문화학회지
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• 제28권6호
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• pp.553-561
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• 2013

This study examined the food purchasing behavior of rural housewives in Bibong-myeon, Hwaseong. The survey targeted grocery shopping for the home, in particular by housewives. The type of grocery store frequented, age, socioeconomic factors, and ease of purchase were compared with interests in health foods. One super supermarket (SSM), three supermarkets (SM), and four convenience stores were examined in the research area, whereas a large-scale discount store and grocery stores were also examined outside the research area. The grocery store visiting rate was 61.5% in the research area and 38.5% in the other area. The SSM (62.7%) and SM (29.9%) in the research area and LDS (57.1%) and SSM (16.7%) in the other area were most frequently visited. Major purchasing products greatly differed according to the grocery store type. Major foods purchased in the SSM were grain, meat, and fish. Major foods purchased in the LDS and SM were processed products and vegetables, respectively. The LDS visiting frequency was 41.7% for 2-3 times per month and 41.7% for <1 time per month. The means of transport were mostly by private car (87.5%), whereas the SSM was visited 1-2 times per week 53.1% of the time by foot. In addition, various grocery stores are absent in rural areas and it is therefore important to find other methods to assess the food environment of rural areas. In future research, it will be necessary to design various ways to perform food environment research.

• 한국자동차공학회논문집
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• 제24권5호
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• pp.527-537
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• 2016

Recent automakers are trying to be more precise with the dimension check and moving parts to guarantee high quality and satisfy customer requirements. The aim of this paper is to investigate the design tolerance suitability of door operating mechanism linked arms, lever, and cam-shaft in a mobile air handling unit. These parts are complicated because doors, arms, lever and cam-shaft are connected nonlinearly in 3D. The current tolerance analysis method poses problems in design analysis because the moving doors are reasonably suitable for the AHU function. The 3-DCS analysis method provided useful results not only in establishing the inspection criteria for the quality control of products but also in enabling economical production. As a result, the vent door had $1.62^{\circ}{\sim}1.72^{\circ}$ and the defrost door had $0.84^{\circ}{\sim}0.9^{\circ}$ for the directly connected arms operating-type. For the lever connected arm operating-type, the foot door had $2.0^{\circ}{\sim}2.24^{\circ}$ tolerance, while the tolerance values satisfied the air flow volume distribution rate criteria in the AHU. Finally, the results have confirmed the design's tolerance suitability by using 3-DCS analysis at the early design stages. Reliability can be achieved by analyzing accumulated tolerance during the sub-parts assembly process and the moving mechanism linked especially by arms, lever, and cam-shaft.

• 한국정보통신학회논문지
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• 제12권6호
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• pp.1095-1100
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• 2008

이 논문에서는 곤충 발자국의 패턴을 인식하기 위해, 인식의 기본 단위인 세그먼트를 자동 추출하는 기법과 Trace transform을 이용하여 발자국 인식에 필요한 특징을 추출하는 기법을 제안하였다. Trace transform 방법을 이용하면 패턴의 이동, 회전, 반사에 불변하는 특징 값을 얻을 수 있다. 이러한 특징 값들은 곤충 발자국과 같이 다양한 변형이 존재하는 패턴을 인식하는 데에 적합하다. 특징 값을 도출하기 위한 첫 번째 단계로는 추출된 세그먼트에 대한 Trace transform을 통해 새로운 Trace 이미지를 생성시킨다. 그런 다음, 병렬로 표현되는 trace-line을 따라 특성 함수에 의해 특징들이 일차적으로 도출되고, 또 다시 도출된 특징들은 diametric, circus 단계의 함수를 거치면서 새로운 특징값으로 재구성된다. 2가지 서로 다른 곤충의 발자국 패턴을 이용하여 실험한 결과 곤충 발자국의 이동, 회전, 반사에 관계없이 인식에 적합한 특징 값들이 추출됨을 확인할 수 있었다.

• PNF and Movement
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• 제19권2호
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• pp.279-285
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• 2021

Purpose: This study aimed to develop new digital navicular drop test (ND-NDT) equipment and to determine its validity and reliability. Methods: A total of 24 healthy male and female adults, who fully understood the purpose of the study and gave consent to participate in the study, were selected as participants. The NDT and ND-NDT were conducted in the dominant foot of the participants in a random order. For the NDT, the position of the navicular bone was marked with a pen first; then, the height of the navicular bone from the ground was measured in both sitting and standing positions. For the ND-NDT, after the sticker-type reflection markers were attached to the position of the navicular bone, the height of the navicular bone from the ground was measured in both sitting and standing positions. To assess the validity of the diagnostic tests, the same examiner measured the height of the medial longitudinal arch (MLA) three times in both the sitting and standing positions. To assess the inter-rater reliability of the ND-NDT, three examiners, in a random order, attached the sticker-type reflection markers to the position of the navicular bone and then measured the height of the MLA in both positions. Results: In the sitting position, the Pearson correlation coefficient (r) between the two diagnostic tests was very high (r = 0.97) and statistically significant. In the standing position, the Pearson correlation coefficient (r) between the two tests was 0.95, which was also statistically significant. The ICC_2,1 values in the sitting and standing positions were 0.93 and 0.95, respectively, indicating significantly high inter-rater reliability. Conclusion: The ND-NDT equipment showed very high diagnostic validity, as well as excellent inter-rater reliability, indicating the clinical usefulness of the equipment as a diagnostic system for confirming pes planus.