• 한국생물공학회:학술대회논문집
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• 2000.04a
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• pp.141-144
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• 2000

Highly open porous polymer matrices are required for high density cell seeding, efficient nutrient, and oxygen supply to the cells cultured in the three dimensional matrices. However, there are severe problems of mass transfer limitations within the cell/scaffolds culture system. Thus we hypothesize that continuos-flow culture conditioning of cells with the scaffolds may improve the cell viability and the differentiated function. In this study, we fabricated porous PLGA scaffolds by using gas-foaming/salt-leaching method as previous described. Viscous PLGA gel paste contains ammonium bicarbonate particulates, acting as a gas-foaming agent as well as a salt-leaching porogen, were cast into Teflon mold and dried. Ammonium bicarbonate salt upon contact to an acidic aqueous solution evloves gaseous ammonia and carbon dioxide by itself. And we conjugated galactose moiety [AGA; $N-(aminobuty1)-O-{\beta}-D-galactopyranosyl-(1{\rightarrow}4)-D-glucoamide]$ to the terminal end group of a PLGA to increase the cell adhesion and matain the differentiated function of hepatocytes. Cell-seeded scaffolds were secured in a flow bioreactor chamber and exposed to continuous flow at 5 ml/min. As a result of our study, the high yield of hepatocytes attachment was accomplished by increasing the concentration of PLGA-AGA conjugate in polymer scaffolds and cells in the scaffolds under continuos flow condition maintained a high level of viability and albumin secretion rate of cultured hepatocytes showed a higher level that of control groups.

• Journal of the Korean Ceramic Society
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• v.50 no.2
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• pp.93-102
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• 2013

Macro porous ceramics possessing controlled microstructures and chemical compositions have increasingly proven useful in the industrial sphere. Their sintered structures have found application in both established and emerging, areas such as thermal insulation in buildings, filtration of liquids and molten materials, refractory insulation, bone scaffolds and tissue engineering. Stable ceramic foams can be formed by wet chemical methods using inorganic particles(e.g., $Al_2O_3$ or $SiO_2$). The wet foams are dried and sintered with improved porosity and mechanical properties. This review examines the different techniques used to prepare porous ceramics from ceramic foams, focusing on the explanation of this versatile method of direct foaming from the past to the present. Comparisons of the processes and the processing parameters are explained with the produced microstructures.

• Proceedings of the KSME Conference
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• 2004.11a
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• pp.991-996
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• 2004

Plastics are widely used in industry, because they are light, easily manufactured, and have high specific strength. And many researches to increase the strengths and to reduce the price are being conducted at now. One of these researches is concerning to additives. Foaming techniques are used to endow insulation properties, to improve specific strength, or reduce the material cost. Due to their unique properties, foamed plastics are applied to refrigerator, pipe, and insulators. Micro-cellular foaming is the latest foaming technique that was invented at 1980 in MIT. It is known that many tiny small cells are generated in the polymer matrices and micro-cellular foamed plastics show relatively high specific strength. We investigated the role of CaCO3 which is one of the most widely used additives in plastics industry as an additive for nucleation in view of cell morphology. CaCO3 used in this paper was treated to increase the dispersibility and to lower the density, so it has many pores at his body. Two experiments were conducted, in order to check the role of an additive for nucleation. One is compound-ability and the other one is role of nucleation agents.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.06a
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• pp.1630-1635
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• 2005

The microstructure of the parts made by the microcellular injection molding process influence properties, including impact strength, tensile strength and density of material. Microstructure of microcellular plastics is divided into core foaming region and solid skin region. Core foaming region is influenced by pressure drop rate, viscosity and cell coalescence. However, actual mechanism of the skin layers is not known despite its importance. The study on the skin layer is getting important because foaming rate of the plastics is determined by the thickness ratio of the skin layer. Especially in case of large molded part, control of the skin layer is needed because skin layer thickness is changed largely. Therefore it is necessary to study variation in skin layer thickness with processing parameters. In this paper, the influence of temperatures in the mold cavity on the skin layer s thickness was also addressed. In addition, the relationship between the temperature distributions across cavity of the mold with impact strength on parts made with the microcellular injection molding process was addressed. In addition, the method to predict the variation in skin layer thickness with mold temperature is discussed.

• Polymer(Korea)
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• v.25 no.5
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• pp.707-718
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• 2001

Polypropylene (PP) exhibits many beneficial properties such as low density high thermal stability, chemical resistance, good processability and recyclability. However, only limited research has been done on expanded polypropylene (EPP). In this study, we were trying to prepare EPP with chemical blowing agent. Ethylene-octene copolymer (mPE) was melt blended with PP to enhance melt fluidity of PP at processing temperature and to make more flexible foamed material. Prior to foaming, phase morphology of PP/mPE blends were investigated to examine the effect of phase morphology on the foaming ratio and cell structure of foams. Phase morphology of PP/mPE blends were affected by the content of mPE and mixing torque ratio. At the same composition, it was affected by mixing rpm. High blowing ratio and stable cell structure were obtained in the blend which has the continuous PP matrix with dispersed droplets of mPE.

• Polymer(Korea)
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• v.24 no.4
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• pp.538-544
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• 2000

The characteristics of cell growth and foamed cell structures of PP were investigated by a continuous foaming process. The operating parameters were the contents of blowing agent and nucleating agent, nucleating agent contents, die temperatures and die dimensions. The foaming cells grew without collapse at less than 14.5 wt% of blowing agent, isopentane. But the cells were collapsed when the blowing agent content was more than 14.5 wt%. The foam density dramatically decreased when a very small amount of the nucleating agent, 1 wt%, was added. After the nucleating agent was added, the cell's weight plummeted to one-seventh of its previous weight. Stable foam cell structures were formed at the die temperature of 17$0^{\circ}C$. However, the effects of the pressure drop rate on the cell morphology were not serious.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2005.05a
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• pp.5-8
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• 2005

Sound absorbing performance is affected by porosity and continuity of void, therefore it is important to maintain stabilization of foam and to analyze properties of void pore in hardened state. The purpose of this study is to analyze the sound absorption properties and void characteristic of foamed concrete according to dilution ratio of foaming agent. The results of this experiment were as follows. It is determined that an increase in total and continuous void ratio is achieved by increasing of dilution ratio, and a shorter absorbing time was exhibited at a higher continuous void ratio. When the average void size of foamed concrete was below 1.5mm, the tendency of sound absorption coefficient compared with general sound absorber was appeared similarly.

• The Journal of the Acoustical Society of Korea
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• v.19 no.2
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• pp.3-7
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• 2000

This paper is on the sensitivity characteristics of a concentric composite mandrel type fiber optic acoustic sensor with inclusion of an air cavity With the finite element method, we have analyzed sensitivity variation of the sensor in relation to its geometrical factors such as thickness of the air cavity, thickness of the foaming layer, and the ratio of inner diameter/outer diameter of the mandrel. Results of the analysis suggest a thicker air cavity, a thinner foaming layer, and a smaller ratio of the inner diameter/outer diameter of the mandrel to be desirable for higher sensitivity. The sensor structure designed with the above rules provides the sensitivity of about 0.8dB higher than that of a normal concentric composite mandrel sensor without the inherent air cavity.

• Journal of Korea Foundry Society
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• v.30 no.6
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• pp.241-246
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• 2010

The viscosity of foam metal is necessary to get the pores, but it is difficult to manufacture net-shape foam, because the fluidity decreases by increasing viscosity. In this study, the A356 alloy which has good fluidity and less defect was selected and fabricated to foam metal. To understand about effect of thickening agent on foaming and mechanical properties, quantity of thickening agent was changed. The pore size, porosity and distribution of foam metal were measured by i-solution program. And compression test were performed by UTM. In case of 3.0wt% Ca in thickening agent, it is found that most of foam consist of homogeneous shape, and the growth height had the highest value of 204 mm in the all fabricated foams. The porosity was 93% and compressive strength was 3.1 MPa. In the microstructure, the $Al_2Si_2Ca$ intermetallic compound and Ti were observed. The vickers hardness value rose with increasing viscosity value.

• Polymer(Korea)
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• v.26 no.4
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• pp.508-515
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• 2002

The effects of the crosslinking caused by irradiation dose, molecular weights of the foaming materials, and various foaming processes on the foam structure of the polypropylene (PP) were investigated. The maximum gel content of the PP was 48% when the sheet was irradiated with 3.2 Mrad. This high gel content improved the cell structures by providing high thermal stability. The increase of both the gel content and structural development were stopped at the irradiation dose exceeding 3.2 Mrad. The increase of the molecular weights served to help produce a foam with particularly fine and even cell structures, along with improved thermal stability as well.