• 한국철도학회:학술대회논문집
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• 한국철도학회 2011년도 춘계학술대회 논문집
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• pp.326-331
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• 2011

Aluminum extruded panel used in a high speed train shows high stiffness, however, its sound insulation performance is remarkably decreased by local resonance phenomena. In this paper, improvement strategy of the sound insulation performance is proposed for the floor extruded panel used in HEMU-400x, 400km/h class next generation high speed train under development, and the improvement effect is verified by experiment. Aluminum extruded panel specimen for the floor is manufactured and urethane foam is installed in the core of the panel. Based on ASTM E2249-02, intensity transmission loss is measured and the improvement effect in local resonance frequency band is verified. Finally, improvement effect of the sound insulation performance is estimated on the layered floor structure including the foamed aluminum panel.

• Biomolecules & Therapeutics
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• 제26권2호
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• pp.121-129
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• 2018

Oxidized low-density lipoprotein (ox-LDL)-induced macrophage foam cell formation and apoptosis play critical roles in the pathogenesis of atherosclerosis. Thioredoxin-1 (Trx) is an antioxidant that potently protects various cells from oxidative stress-induced cell death. However, the protective effect of Trx on ox-LDL-induced macrophage foam cell formation and apoptosis has not been studied. This study aims to investigate the effect of recombinant human Trx (rhTrx) on ox-LDL-stimulated RAW264.7 macrophages and elucidate the possible mechanisms. RhTrx significantly inhibited ox-LDL-induced cholesterol accumulation and apoptosis in RAW264.7 macrophages. RhTrx also suppressed the ox-LDL-induced overproduction of lectin-like oxidized LDL receptor (LOX-1), Bax and activated caspase-3, but it increased the expression of Bcl-2. In addition, rhTrx markedly inhibited the ox-LDL-induced production of intracellular reactive oxygen species (ROS) and phosphorylation of p38 mitogen-activated protein kinases (MAPK). Furthermore, anisomycin (a p38 MAPK activator) abolished the protective effect of rhTrx on ox-LDL-stimulated RAW264.7 cells, and SB203580 (a p38 MAPK inhibitor) exerted a similar effect as rhTrx. Collectively, these findings indicate that rhTrx suppresses ox-LDL-stimulated foam cell formation and macrophage apoptosis by inhibiting ROS generation, p38 MAPK activation and LOX-1 expression. Therefore, we propose that rhTrx has therapeutic potential in the prevention and treatment of atherosclerosis.

• 한국해양환경ㆍ에너지학회지
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• 제20권2호
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• pp.63-75
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• 2017

해양환경에서 파랑-구조물 상호작용의 정확한 예측은 극한 환경조건에 노출 된 고정식 및 부유식 해양구조물의 안전성과 설계비용 효율성에 있어서 중요하다. 본 연구에서는 규칙파 와 원형 기둥의 파랑-구조물 상호작용을 해석하였다. 3차원 이상유동(two-phase flow)을 해석하기 위해 오픈소스 전산유체역학 라이브러리인 OpenFOAM을 사용하였다. 수치파랑수조에서 파를 생성 및 흡수하기 위해 소스항을 이용한 relaxation method를 적용하였다. 수치기법을 검증하기 위해 심해조건에서 생성된 2차 stokes 파형은 이론적인 해와 비교하였다. 검증과정을 통해 파장과 진폭에 대한 길이 및 높이 방향의 격자크기를 정하였다. 원형 기둥에 작용하는 파랑 하중과 wave run-up을 계산하고 기존의 실험 데이터와 비교하였다.

• 한국복합재료학회:학술대회논문집
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• 한국복합재료학회 2005년도 추계학술발표대회 논문집
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• pp.179-184
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• 2005

In the present study, conceptual design of the main wing for 20 seats WIG{wing in Ground Effect) flight vehicle, which will be a high speed maritime transportation system for the next generation, was performed. The high stiffness and strength Carbon-Epoxy material was used for the major structure and the skin-spar with a foam sandwich structural type was adopted for improvement of lightness and structural stability. As a design procedure for this study, firstly the design load was estimated with maximum flight load, and then flanges of the front and the rear spar from major bending load and the skin structure and the webs of the spars were preliminarily sized using the netting rules and the rule of mixture. In order to investigate the structural safety and stability, stress analysis was performed by Finite Element Codes such as NASTRAN/PA TRAN[6] and NISA II [7]. From the stress analysis results, it was confirmed that the upper skin structure between the front spar and rear spar was very unstable for the buckling. Therefore in order to solve this problem, a middle spar and the foam sandwich structure at the upper skin and the web were added. After design modification, even thought the designed wing weight was a little bit heavier than the target wing weight, the structural safety and stability of the final design feature was confirmed. Moreover, in order to fix the wing structure at the fuselage, the insert bolt type structure with six high strength bolts was adopted for easy assembly and removal.

• 대한원격탐사학회지
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• 제27권4호
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• pp.403-410
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• 2011

연안 환경에 대한 효과적인 관측을 위해서는 높은 주기 및 공간 해상도의 지속적인 관측이 필요하다. 지상에 설치한 기기로부터 이루어지는 원격 관측은 소수의 현장 기기 개수로는 관측할 수 없는 넓은 범위의 해역을 통시에 관측할 수 있고 또한 높은 빈도의 지속적인 관측이 가능하다. 본 연구에서는 연안 환경에 대한 대표적인 지상 원격 관측 기기인 마린 레이다와 카메라 시스템의 활용에 대하여 고찰해본다. 마린 레이다는 시간적으로 연속된 레이다 영상으로부터 파수 스펙트럼을 계산하고 이를 통합 적분하고 조정 전달함수를 적용하여 시간에 따른 주파수 스펙트럼을 산출할 수 있다. 또한 시간에 따른 파랑 레이다 영상을 평균함으로서 쇄파대와 이안류 그리고 연안사주의 위치 등에 대한 분석도 기능하다. 카메라 시스템은 해안선의 변화뿐만 아니라 오염 등으로 인하여 해안에서 발생하는 거품 발생량의 변화에 대한 분석을 할 수 있다. 빗각 촬영된 거품 영상을 기하 보정 후 거품부분을 따로 추출함으로서 거품량에 대한 정량적인 분석이 가능하다. 위의 두 기기는 각기 그 특성이 다른 센서로서 이를 동시에 활용하면 연안환경 관측에 있어 시너지 효과를 얻을 수 있다.

• 한국식품영양과학회:학술대회논문집
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• 한국식품영양과학회 2004년도 Annual Meeting and International Symposium
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• pp.265-270
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• 2004

Coronary heart disease (CHD) has been the number one killer in western society for a long time, and CHD in most instances is due to atherosclerosis. One of the earliest events in atherogenesis is the intracellular accumulation of lipids, particularly cholesterol esters, in the aortic intima. The lipids presumably came from the uptake of plasma lipoproteins, particularly from LDL. These foam cells were identified as being predominantly as macrophages. Currently, it is believed that oxidation of low density lipoprotein (LDL) might contribute to the generation of foam cells. An outcome of the oxidation hypothesis is that the consumption of antioxidants would be beneficial. In this study, Boldine, an alkaloid of Peumus boldus was tested for their antioxidant potency both in, in vitro oxidation system and in mouse models. Boldine decreased the ex-vivo oxidation of Low-density lipoprotein (LDL). In vivo studies were performed to study the effect of these compounds on the atherosclerotic lesion formation in LDL r-/- mice. Three groups of LDL r-/- mice (N=12 each) were fed an atherogenic diet. Group 1 was given vehicle and group 2 and 3 were given 1 and 5 mg of Boldine/day in addition to the atherogenic diet. The results indicated that there was a decrease in lesion formation reaching a 40% reduction due to Boldine compared to controls. The in vivo tolerance of Boldine in humans (has been used as an herbal medicine in other diseases) should make it an attractive alternative to vitamin E.

• Journal of Advanced Research in Ocean Engineering
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• 제4권2호
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• pp.78-85
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• 2018

This paper presents a study of the effects of the free surface to marine propeller including the mesh effect of the models. In the present study, we conduct the numerical simulation for propeller performance employing the openwater test. The numerical simulations compare the meshing strategies for the propeller and show the effects on both thrust and torque. OpenFOAM is applied to solve the propeller problem and then open water performances of KCS propeller (KP505) are estimated using a Reynold-averaged Navier-Stokes equations (RANS) solver and the turbulence of the $K-{\omega}$ SST model. Unstructured meshes are used in the numerical simulation employing hexahedral meshing for mesh generation. The arbitrary mesh interfacing (AMI) and multiple rotating frame (MRF) are compared to define the best meshing strategy. The meshing strategies are evaluated through 3 classifications, i.e., coarse, medium, and fine mesh. Thus, the propeller can be performed utilizing the best mesh strategy. The computational results are validated by comparison with the experimental results. The $K_T$, $K_Q$, and efficiency of the propeller are compared to an experimental result and for all of the meshing strategies. Thus, the simulations show the influence of meshing in order to perform the propeller performances.

• 한국주조공학회지
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• 제36권6호
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• pp.208-214
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• 2016

Casting defects, which are closely related to entrapped air bubbles and metallic oxides, occur very frequently in the casting process. Many researchers have shown that these defects can be reduced by adopting an appropriate gating system design. But, it is difficult for field engineers to identify a specific gating system that is more appropriate for their products. In this study, we tried to draw a comparison of gating system designs with and without ceramic foam filters. A ceramic foam filter was added to the horizontal runner just after the sprue to prevent air bubble generation and to reduce turbulence without change of the gating system design. To verify the effects of initial pouring velocity, the experiment was conducted with four different amounts of water volume in the reservoir. Results of the water modeling experiment applying the filter showed remarkably changed flow characteristics. Although the study confirmed that use of the filter may change the flow characteristics, it needs to be noted that only filter use alone cannot solve all the problems caused by a poorly designed gating system.

• 대한물리의학회지
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• 제15권4호
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• pp.1-9
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• 2020

PURPOSE: The current generation has shortened hamstrings due to a sedentary lifestyle, resulting in reduced flexibility of the hamstring and dysfunction. This study was undertaken to compare effects of three different release exercises on hamstring flexibility, in participants with short hamstrings. METHODS: Totally, 20 subjects having short hamstrings were involved in this study. The inclusion criterion for study participation was active knee extension test (AKET) less than 60°. All participants were subjected to 3 methods: hamstring foam roller release (HFRR), sitting self myofascial release (sitting SMR), and standing self myofascial release (Standing SMR). All participants randomly performed all three methods to avoid bias caused by learning or fatigue. Passive knee extension test (PKET), AKET, finger to floor distance test (FTFT), and pelvic tilting angle test (PTAT) were measured pre- and post-exercises. RESULTS: The PKET, AKET and FTFT were significantly increased after HFRR, sitting SMR, and standing SMR exercise (p < .05). However, PTAT was not significantly increased after the three exercises (p > .05). Furthermore, no significant differences were observed between PKET, AKET, FTFT and PTAT subsequent to HFRR, sitting SMR, and standing SMR (p > .05). CONCLUSION: Our results indicate that HFRR, sitting SMR and standing SMR were immediately effective in improving hamstring flexibility in participants with short hamstrings.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2020년도 봄 학술논문 발표대회
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• pp.77-78
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• 2020

In Korea, more than 30,000 tons of waste Styrofoam are produced every year. Styrofoam is spent more than 500 years decomposing during the reclamation process, so it needs to be recycled. The recycling rate of waste styrofoam continues to be the third highest in the world, but it is lower than that of Germany and Japan. Therefore, measures are needed to increase the recycling rate of waste Styropol. Another problem is that cement is mainly used in existing lightweight foam concrete. However, large amounts of CO2 from cement-producing processes cause environmental pollution. Currently, Korea is increasing its greenhouse gas reduction targets to cope with energy depletion and climate change, and accelerating efforts to identify and implement reduction measures for each sector. In 2013 alone, about 600 million tons of carbon dioxide was generated in the cement industry. Therefore, this study replaces CO2 generation cement with furnace slag fine powder, uses crude steel cement for initial strength development of bubble concrete, and manufactures hardening materials to study its properties using waste styrofoam. As a result of the experiment, the hardening agent replaced by micro powder of furnace slag was less intense and more prone to absorption than cement using ordinary cement. Further experiments on the segmentation and strength replenishment of furnace slag are believed to contribute to the manufacture of environmentally friendly lightweight foam concrete.