• Title/Summary/Keyword: Fn

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A Study on the Formation of Nitrate in Atmosphere(II) (환경 대기중에서 Nitrate의 생성에 관한 연구(II))

  • 천만영;이영재;김희강
    • Journal of Korean Society for Atmospheric Environment
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    • v.9 no.3
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    • pp.216-221
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    • 1993
  • This study was carried out to determine the concentration of gaseous nitrate$(HNO_3)$ particulate nitrate$(NO_3^-)$ and conversion rate of NOx to nitrate in atmosphere in Seoul from Oct 1991 to July 1992. The average concentration of gaseous nitrate in daytime(09:00 - 17:00) was 9.93, 3.37, 7.40 and 10.40$\mug/m^3$ and, in highttime was 6.21, 7.31, 4.79 and 3.86$\mug/m^3$ respectively. The concentratin of $HNO_3$ was greater in summer and daytime than winter and nighttime. But the concentration of $NO_3^-$ was greater in winter and nighttime than in summer and daytime. The average conversion rate of NOx to $HNO_3$(Fn) indaytime was 13.18, 3.78, 9.13 and 23.13% and, in nighttime was 3.06, 1.37, 1.70 and 8.72% during fall, winter, spring and summer respectively. But the average conversion rate of NOx to $NO_3^-$(Fn') in daytime was 5.79, 5.77, 2.63 and 3.90% and in nighttime was 5.95, 6.51, 3.25 and 4.84% respectively. The average conversion rate of NOx to total nitrate $(HNO_3 + NO_3^-)$(Fn') was 12.72, 7.81, 7.82 and 18.40% respectively. The average conversion rate of NOx to $HNO_3$(Fn) was greater than $NO_3^-$(Fn') about 1.6 times.

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Incidence, Risk Factors, and Outcomes of Febrile Neutropenia in Thai Hematologic Malignancy Patients Receiving Chemotherapy: A 6-year Retrospective Cohort Study

  • Limvorapitak, Wasithep;Khawcharoenporn, Thana
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.5945-5950
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    • 2015
  • A 6-year retrospective cohort study was conducted among Thai hematologic malignancy (HM) patients receiving intensive chemotherapy. Of the 145 eligible patients receiving 893 chemotherapy sessions, 46.9% were female, median age was 52 years, and the most common HM diagnosis was diffuse large B-cell lymphoma (46.2%). Febrile neutropenia (FN) occurred in 14.9% of chemotherapy sessions with an incidence of 24.8 per 1,000 chemotherapy cycles per year. Independent factors associated with FN were receiving the first chemotherapy cycle [adjusted hazard ratio (aHR) 4.1], having hemoglobin ${\leq}100g/L$ (aHR 3.7) and platelet ${\leq}140,000/{\mu}L$ (aHR 2.7) on chemotherapy day and receiving acute myeloid leukemia regimens (aHR 20.8). Granulocyte colony stimulating factor was significantly associated with reduced rate of FN when given in those receiving CHOP regimen. With the median follow-up time of 16 months, the overall survival time was significantly longer in patients without FN than those with FN (61.7 vs. 20.8 months; p<0.001).

Theoretical and Experimental 31P NMR and ESI-MS Study of Hg2+ Binding to Fenitrothion

  • Koo, In-Sun;Ali, Dildar;Yang, Ki-Yull;vanLoon, Gary W.;Buncel, Erwin
    • Bulletin of the Korean Chemical Society
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    • v.30 no.6
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    • pp.1257-1261
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    • 2009
  • We present the theoretical and experimental results of $^{31}P$ NMR and low energy CID MS/MS study of $Hg^{2+}$ binding to fenitrothion (FN). The calculated $^{31}P$ NMR chemical shifts order for FN with $Hg^{2+}$ complex is in good agreement with experimental $^{31}P$ NMR chemical shifts order. The experimental and theoretical $^{31}P$ NMR study of organophosphorus pesticide with $Hg^{2+}$ gives to important information for organophosphorus pesticide metal complexes. ESI-MS and low energy CID MS/MS experiments of $Hg^{2+}$-FN complexes combined with accurate mass measurements give insight into the metal localization and allow unambiguous identification of fragments and hydrolysis products.

Carboxy-terminus truncations of Bacillus licheniformis SK-1 CHI72 with distinct substrate specificity

  • Kudan, Sanya;Kuttiyawong, Kamontip;Pichyangkura, Rath
    • BMB Reports
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    • v.44 no.6
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    • pp.375-380
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    • 2011
  • Bacillus licheniformis SK-1 naturally produces chitinase 72 (CHI72) with two truncation derivatives at the C-terminus, one with deletion of the chitin binding domain (ChBD), and the other with deletions of both fibronectin type III domain (FnIIID) and ChBD. We constructed deletions mutants of CHI72 with deletion of ChBD (CHI72${\Delta}$ChBD) and deletions of both FnIIID and ChBD (CHI72${\Delta}$FnIIID${\Delta}$ChBD), and studied their activity on soluble, amorphous and crystalline substrates. Interestingly, when equivalent amount of specific activity of each enzyme on soluble substrate was used, the product yield from CHI72-${\Delta}$ChBD and CHI72${\Delta}$FnIIID${\Delta}$ChBD on colloidal chitin was 2.5 and 1.6 fold higher than CHI72, respectively. In contrast, the product yield from CHI72${\Delta}$ChBD and CHI72${\Delta}$FnIIID-${\Delta}$ChBD on ${\beta}$-chitin reduced to 0.7 and 0.5 fold of CHI72, respectively. These results suggest that CHI72 can modulate its substrate specificities through truncations of the functional domains at the C-terminus, producing a mixture of enzymes with elevated efficiency of hydrolysis.

Batch Processing Algorithm for Moving k-Farthest Neighbor Queries in Road Networks (도로망에서 움직이는 k-최원접 이웃 질의를 위한 일괄 처리 알고리즘)

  • Cho, Hyung-Ju
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2021.07a
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    • pp.223-224
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    • 2021
  • Recently, k-farthest neighbor (kFN) queries have not as much attention as k-nearest neighbor (kNN) queries. Therefore, this study considers moving k-farthest neighbor (MkFN) queries for spatial network databases. Given a positive integer k, a moving query point q, and a set of data points P, MkFN queries can constantly retrieve k data points that are farthest from the query point q. The challenge with processing MkFN queries in spatial networks is to avoid unnecessary or superfluous distance calculations between the query and associated data points. This study proposes a batch processing algorithm, called MOFA, to enable efficient processing of MkFN queries in spatial networks. MOFA aims to avoid dispensable distance computations based on the clustering of both query and data points. Moreover, a time complexity analysis is presented to clarify the effect of the clustering method on the query processing time. Extensive experiments using real-world roadmaps demonstrated the efficiency and scalability of the MOFA when compared with a conventional solution.

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Production of the recombinant fibronectin-binding protein of Staphylococcus aureus (Staphylococcus aureus의 재조합 fibronectin-binding protein의 생산)

  • kim, Doo;Cheong, Cha-ryong;Park, Hee-myong;Han, Hong-ryul
    • Korean Journal of Veterinary Research
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    • v.37 no.4
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    • pp.875-882
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    • 1997
  • To produce the recombinant fibronectin-binding protein(FnBP) for development of subunit vaccine against Staphylococcus aureus. The fnbp gene was amplified from the chromosomal DNA of S aureus KNU 196 strain using the polymerase chain reaction, and cloned into pGEX-4T-2. Then, the recombinant FnBP fused with glutathione-S-transferase was produced in E coli, purified by affinity chromatography, and identified its antigenicity and immunogenicity by Western blot. The recombinant FnBP produced in this study is considered to have the same property of native FnBP purified from S aureus, and is expected to be useful as a candidate for S aureus subunit vaccine.

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A Study on the Risk Assessment for Oil Immersed Transformer of Subway with FN curve (지하철 유입 변압기의 FN 선도를 이용한 위험도 평가 연구)

  • Choi, Seung Hyeok;Lee, Jong Woo
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.63 no.8
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    • pp.1152-1158
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    • 2014
  • In Modern society, various important systems is operated such as nuclear plant, chemistry industry, railway system and so on. But these systems can cause high risky accidents. Hence, these systems are required to ensure the individual and societal risk criteria. In this paper, we reviewed EU risk criteria which is already operated in UK and Netherlands, then we proposed acceptable risk criteria and estimated risk of oil immersed transformer for subway with FN curve.

A Functional Role of Fibronectin Receptors in the Monocyte Differentiation (단핵구 분화에 있어서 Fibronectin 수용체의 역할)

  • 방옥선;강희갑박의균이영섭
    • The Korean Journal of Zoology
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    • v.37 no.4
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    • pp.592-596
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    • 1994
  • The interaction between fibronectin (FN) and its receptors controls cell attachment and migration, two crucial events during monocyte development and differentiation. To investigate the functional role of FN and its receptor, we have studied adhesion of monocyte to two different regions of FN (38- and 85-kDa domain), as well as the expression of the integrin during monocle differentiation. Anti-integrin Rl subunit antibody completely blocked the attachment of FN-coated latex beads to macrophage, but the effect of anti-integrin u4 antibody was much less significant. Rat monocyte expressed integrin $u4\beta1$ predominantly, while macrophage expressed $\alpha5\beta1$ as analyzed tv flow cvtometer and western blot. From these results, it can be suggested that these two integrins plan different roles during monocyte differentiation.

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A Possible Role of Fibronectin on the Differentiation of Monocyte to Macrophase (단핵구 분화에 대한 Fibronectin 및 그 단편의 역할)

  • Ok Sun Bang;You
    • The Korean Journal of Zoology
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    • v.36 no.4
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    • pp.514-521
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    • 1993
  • Monocyte interaction with fibronectin (FN) mediates specific cell surface receptors and results in cell attachment and differentiation. Several cell-mediated activities for various fragments of FN have been documented. To investigate the regulatory mechanisms of monocyte differentiation by cell binding domains of FN and their receptors, cell attachment-, cell migration-, and its respective inhibition assay were carried out. Monocyte recognizes 38-kDa domain distinctively from its recognition of 85-kDa domain, and the heparin-binding site of the 38-kDa fragment is not involved in monocyte adhesion. Based on these experimental results, it can be suggested that monocvte/macrophase interacts with at least two different sites in FN, which is critical step in cell adhesion and (or) migration.

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Performance improvement of heuristic algorithm to assign job in parallel line inspection process (병렬라인 검사공정의 작업배분을 위한 휴리스틱 알고리즘의 성능 개선)

  • Park, Seung-Hun;Lee, Seog-Hwan
    • Journal of the Korea Safety Management & Science
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    • v.14 no.1
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    • pp.167-177
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    • 2012
  • In this paper, we raised the performance of heuristic algorithm to assign job to workers in parallel line inspection process without sequence. In previous research, we developed the heuristic algorithm. But the heuristic algorithm can't find optimal solution perfectly. In order to solve this problem, we proposed new method to make initial solution called FN(First Next) method and combined the new FN method and old FE method using previous heuristic algorithm. Experiments of assigning job are performed to evaluate performance of this FE+FN heuristic algorithm. The result shows that the FE+FN heuristic algorithm can find the optimal solution to assign job to workers evenly in many type of cases. Especially, in case there are optimal solutions, this heuristic algorithm can find the optimal solution perfectly.