• YAKHAK HOEJI
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• v.35 no.5
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• pp.353-359
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• 1991

Treatment of 1-ethyl-6-fluoro-1, 4-dihydro-4-oxo-7-(l-piperazinyl)-I, 8- naphthyridine-3-ca rboxylic acid (Enoxacin) with alkyl(or aryl) isothiocyanates which obtained from alkyl(or aryl) amines afforded six 1-ethyl-6-fluoro-1, 4-dihydro-4-oxo-7-(1-alkylthiocarbamylpiperazinyl)-1, 8- naphthyridine-3-carboxylic acids and five 1-ethyl-6-fluoro-1, 4-dihydro-4-oxo-7-(l-arylthiocarbamyl piperazinyl)-1, 8-naphthyridine-3-carboxylic acids. The compounds synthesized were evaluated for their antimicrobial activities, in vitro, against Escherichia coli 6-PE-4, Bacillus subtilis 74-51, Proteus vulgaris 78645, Klebsiella pneumoniae JYA-78314, Staphylococcus aureus 79110 and Pseudomonas aeruginosa 8765-1 P$_{2}$.

• The Korean Journal of Pesticide Science
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• v.12 no.2
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• pp.103-110
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• 2008

To develop the third generation herbicidal cyclic imide (Cyl) derivatives, the new 1-(4-chloro-2-fluoro-5-propargyloxyphenyl)-3-thiourea derivatives were synthesized and measured their herbicidal activities ($pI_{50}$) in vivo (preemergence) against rice plant (Orysa Sativa) and barnyard grass (Echinochlor crus-galli). The synthetic yields (%) of aryl derivatives (21-40) in general was higher than that of alkyl derivatives (1-20). In case of alkyl derivatives, the synthetic yield depended on the structural forms of alkyl amine groups. From the results of correlation analysis between herbicidal activities and substituents, the compound 8 and 24 showed the highest herbicidal activity against the shoot and root of barnyard grass. Especially, the compounds 11 and 6 showed the selective herbicidal activities between rice plant and barnyard grass.

• Journal of the Korean Ceramic Society
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• v.19 no.2
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• pp.109-114
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• 1982

Fluoro-phlogopite crystals (Mica) were synthesized by two different methods; firstly the crystal was crystallized from the melts, and secondly mica crystalline was obtained from the direct solid state reaction. Addition of $CaF_2$ in the mica batch revealed the lowering the solid state reaction temperature. SEM and XRD were employed to observe mica crystalline flakes and solid solution forms. As a starting raw material Pyrophyllite was used resulting in the formation of mica crystals.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2001.11a
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• pp.81-81
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• 2001

The photoinducible DNA cleaving activities of bromofluoroacetophenones as a novel photonuclease were investigated. The photolytic behavior and DNA cleaving acitivity of fluorine derivative were compared with those of non-fluorine substituted compound, 4'-bromoacetophenones. Although the DNA cleaving activities of fluorine analogs were similar with those of 4'-bromoacetophenones, ο-bromo-$\rho$-fluoro derivatives gave the better DNA cleaving activities than $\rho$-bromo-ο-fluoro derivatives did.

• 한국정보디스플레이학회:학술대회논문집
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• 2002.08a
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• pp.483-486
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• 2002

Tree-ring types liquid crystalline compounds having fluoro and isothiocyanate substituent[1] were synthesized and their physical properties were measured to evaluate the applications to TFT-LCD TV. All synthesized compounds were showed remarkably high Tni point. Birefringence(${\triangle}n$) and dielectric anisotropy(${\triangle}{\varepsilon}$) were higher than fluoro analogues and isothiocyanate substituted bicyclohexyl-phenyl compounds.

• Journal of the Korean Chemical Society
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• v.41 no.4
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• pp.214-218
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• 1997

• Archives of Pharmacal Research
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• v.19 no.3
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• pp.243-245
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• 1996

• Bulletin of the Korean Chemical Society
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• v.11 no.5
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• pp.376-379
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• 1990

To find out a correlation between antibacterial activity and physical properties of 7-substituted 1-ethyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, dipole moments, charge distributions, and hydrophobicities were calculated. The atomic charges and the dipole moments to not give any correlations with inhibition of DNA gyrase, but the calculated hydration free energies show some correlations.

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.366.2-366.2
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• 2002

In an effort to search for the chemically and enzymatically stable carbonucleoside. we designed ［1'-fluoro-2', 2'-bis-(hydroxymethyl) cyclopropyl methyl］ purines. The underlying concept for our design is to seek relatively conformationally-locked compound with minimal structural disturbance from acyclic carbonucleoside such as acyclovir or penciclovir. To meet such a requirement. we need to introduce cyclopropane and fluorine moiety. (omitted)

• Journal of the Korean Chemical Society
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• v.54 no.6
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• pp.711-716
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• 2010

New electroluminescent polymers with fluoro groups in vinylene units, poly(m-silylphenyl-p-phenylene-difluorovinylene) (m-SiP-PPDFV) have been synthesized by GILCH polymerization. These polymers have been used as the electroluminescent (EL) layers in single layer light-emitting diodes (LEDs) (ITO/PEDOT/polymer/Ca:Al). m-SiP-PPDFV shows PL around $\lambda_{max}$ = 452 nm and green EL around $\lambda_{max}$ = 497 nm. The current-voltage-luminance (I-V-L) characteristics of the polymers show turn-on voltages of 4.0 V approximately. Two fluoro groups were introduced on every vinylene units of m-SiP-PPV to give m-SiP-PPDFV in an attempt to increase the electron affinity of the parent polymer, and the devices show an increased color stability even with vinylene units. The color stability is attributed to the electron-withdrawing effect of the fluoro groups, which protect vinylene units from oxidation in PPV derivatives. We believe that fluoro groups can be introduced in vinylene units in order to attain excellent stability of PPV derivatives.