• Title/Summary/Keyword: Fluids interference

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Development of Enzyme Immobilization Method to Remove Interference by Physiological Chemicals for Implantable Glucose Sensors (이식형 혈당 센서의 생리활성 물질에 의한 방해 효과를 제거하기 위한 새로운 효소고정법 개발)

  • Chung, T.D.;Kim, H.C.
    • Proceedings of the KOSOMBE Conference
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    • v.1998 no.11
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    • pp.72-73
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    • 1998
  • A new method for enzyme immobilization has been developed to remove interference by potential interferents in body fluids. Instead of using electron mediators, we chose direct hydrogen peroxide measurement route. Extremely hydrogen peroxide-selective polymer was coated as an inner membrane to exclude interferents and then glucose oxidase(GOx) was entrapped by electropolymerization of inert monomers. There was no solvent casting step throughout the whole fabrication procedure but all membranes on Pt-Ir electrode were formed by electropolymerization. Thus, membrane thickness, quantity of enzyme loaded and can be controlled by electrochemical parameters. As a result, reproducibility of biosensor characteristics becomes remarkably improved in terms of mass production.

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A numerical parametric study on hydrofoil interaction in tandem

  • Kinaci, Omer Kemal
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.7 no.1
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    • pp.25-40
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    • 2015
  • Understanding the effects of the parameters affecting the interaction of tandem hydrofoil system is a crucial subject in order to fully comprehend the aero/hydrodynamics of any vehicle moving inside a fluid. This study covers a parametric study on tandem hydrofoil interaction in both potential and viscous fluids using iterative Boundary Element Method (BEM) and RANSE. BEM allows a quick estimation of the flow around bodies and may be used for practical purposes to assess the interaction inside the fluid. The produced results are verified by conformal mapping and Finite Volume Method (FVM). RANSE is used for viscous flow conditions to assess the effects of viscosity compared to the inviscid solutions proposed by BEM. Six different parameters are investigated and they are the effects of distance, thickness, angle of attack, chord length, aspect ratio and tapered wings. A generalized 2-D code is developed implementing the iterative procedure and is adapted to generate results. Effects of free surface and cavitation are ignored. It is believed that the present work will provide insight into the parametric interference between hydrofoils inside the fluid.

Use of CFD for Aerodynamic Interference Modelling of Jet-Controlled Missile (측추력 제어 유도탄의 공력모델링시 CFD의 적용)

  • Sung W. J.;Hong S. K.;Ahn C. S.
    • 한국전산유체공학회:학술대회논문집
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    • 2003.08a
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    • pp.120-125
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    • 2003
  • Recently, lateral jet has been adopted as an effective control device for high maneuverable tactical missiles in supersonic regime. Aerodynamic interference caused by the lateral jet can be categorized into two phenomena : local interaction redistributing surface pressure near the jet exit region and downstream interaction affecting tail control effectiveness. As part of on-going research, this paper deals with the aerodynamic modeling to predict the variation of force and moment when lateral jet of is activated on the missile body. For this purpose, a series of numerical simulation has been performed and the results are presented. Using the information obtained by CFD, aerodynamic model of preliminary level has been constructed and is reviewed. Some relevant comparison with wind tunnel tests are presented.

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NUMERICAL STUDY OF MODEL AND WALL INTERFERENCE IN A SUPERSONIC WIND TUNNEL (초음속 풍동내에서의 모델과 벽면 간섭에 관한 수치적 연구)

  • Hong S. K.;Ahn H. K.
    • 한국전산유체공학회:학술대회논문집
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    • 1995.10a
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    • pp.213-218
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    • 1995
  • 마하수 4일때 초음속 풍동의 벽면과 모델지지부의 간섭에 관해 연구하였다. 특히 모델지지부 주위에서의 충격파 형성과 sting, strut 그리고 second throat에서의 반사 충격파의 상호 작용에 연구의 촛점을 두었다. 수치 기법은 내재적 플럭스 차분 분할기법 (implicit flux-difference splitting technique)을 사용하였다. 2차원과 3차원 유동해석 결과로부터 모델지지부 후류의 유동에 미치는 diffuser 출구 경계조건의 영향을 알아보았다.

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Effect of Partition within Opening on Helium-Air Exchange Flow (개구부에 삽입한 수직평판이 헬륨.공기치환류에 미치는 영향)

  • Tae-il Kang
    • Journal of Advanced Marine Engineering and Technology
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    • v.27 no.6
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    • pp.797-805
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    • 2003
  • This paper describes experimental investigations of helium-air exchange flow through single opening and partitioned opening. Such exchange flows may occur following rupture accident of stand pipe in high temperature gas cooled reactor. A test vessel with a small opening on top of test cylinder is used for experiments. An estimation method of mass increment is developed and applied to measure the exchange flow rate. A technique of flow visualization by Mach-Zehnder interferometer is provided to recognize the exchange flows. Flow measurements are made with the opening, for partition ratios H_p/H$_1$$ in the range 0 to 1. where H_p$ and H$_1$ are partition length and height of the opening. respectively. In the case of H_p/H$_1$$ of 0, flow passages of upward flow of the helium and downward flow of the air within the opening are unseparated (bidirectional), and the two flows interfere within the opening. The unseparated flow increases strength of flow resistance and therefore, the exchange flow rate is minimum through range of the partition ratios. Two flow zones, i.e., separated (unidirectional) flow zone and unseparated (bidirectional) flow zone, exist with increasing the partition length. The exchange flow rate increases with increasing the separated flow zone. It is found that a maximum exchange flow rate exists at H_p/H$_1$$ of 1. As a result of comparison of the exchange flow rates by changing the partition ratio, the fluids Interference in the unseparated zone is found to be an important factor on the helium-air exchange flow rate.

ANALYSIS OF VORTEX SHEDDING PHENOMENA AROUND PANTOGRAPH PANHEAD FOR TRAIN USING LARGE EDDY SIMULATION (LES를 이용한 판토그라프 팬헤드의 와 흘림 현상 해석)

  • Jang, Yong-Jun
    • Journal of computational fluids engineering
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    • v.16 no.2
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    • pp.17-23
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    • 2011
  • The turbulent flow and vortex shedding phenomena around pantograph panhead of high speed train were investigated and compared with available experimental data and other simulations. The pantograph head was simplified to be a square-cross-section pillar and assumed to be no interference with other bodies. The Reynolds number (Re) was 22,000. The LES(large eddy simulation) of FDS code was applied to solve the momentum equations and the Wener-Wengle wall model was employed to solve the near wall turbulent flow. Smagorinsky model($C_s$=0.2) was used as SGS(subgrid scale) model. The total grid numbers were about 9 millions and the analyzed domain was divided into 12 multi blocks which were communicated with each other by MPI. The time-averaged mainstream flows were calculated and well compared with experimental data. The phased-averaged quantities had also a good agreement with experimental data. The near-wall turbulence should be carefully treated by wall function or direct resolution to get successful application of LES methods.

CONTROL OF SQUARE CYLINDER FLOW USING PLASMA SYNTHETIC JETS (플라즈마 합성제트를 이용한 사각 실린더 유동의 제어)

  • Kim, Dong-Joo;Kim, Kyoung-Jin
    • Journal of computational fluids engineering
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    • v.17 no.2
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    • pp.85-92
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    • 2012
  • Flows over a square cylinder with and without plasma actuation are numerically investigated to see whether plasma actuation can effectively modify vortex shedding from the cylinder and reduce the drag and lift fluctuations. In this study, a plasma synthetic jet actuator is mounted on the rear side of cylinder as a means of direct-wake control. The effect of plasma actuation is considered by adding a momentum forcing term in the Navier-Stokes equations. Results show that the reduction of mean drag and lift fluctuations is obtained for both steady and unsteady actuation. However, the steady actuation is better than the unsteady one in terms of mean drag as well as drag fluctuations. With the strong steady actuation considered, the interaction of two separating shear layers from rear corners is effectively weakened due to the interference of synthetic jets. It results in a merging of synthetic-jet and shear-layer vortices and the increase of vortex shedding frequency. On the other hand, the unsteady actuation generates pulsating synthetic jets in the near wake, but it does not change the vortex shedding frequency for the actuation frequencies considered in this study.

A STUDY ON THE AERODYNAMIC DRAG REDUCTION OF HIGH-SPEED TRAIN USING BOGIE SIDE FAIRING (고속열차 대차 측면 페어링 적용을 통한 공기저항 저감 연구)

  • Moon, J.S.;Kim, S.W.;Kwon, H.B.
    • Journal of computational fluids engineering
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    • v.19 no.1
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    • pp.41-46
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    • 2014
  • The aerodynamic drag of high-speed train has been calculated and the effect of bogie side fairing on the aerodynamic drag has been investigated. Computational Fluid Dynamics (CFD) simulation based on steady-state 3 dimensional Navier-Stokes equation has been conducted employing FLUENT 12 and the aerodynamic model of HEMU-430x, the Korean next generation high-speed train under development has been built using GAMBIT 2.4.6. Three types of bogie side fairing configuration, the proto-type without fairing, half-covered fairing to avoid the interference with the bogie frame and full-covered fairing have been adopted to the train model to compare the drag reduction effects of the bogie side fairing configurations and the numerical results yields that the bogie side fairing can reduce the aerodynamic drag of the 6-car trainset up to 7.8%. The aerodynamic drag coefficient of each vehicle as well as the flow structures around the bogie system have also been examined to analyze the reason and mechanism of the drag reduction by bogie side fairing.

Analysis of DA-6034, a New Flavonoid Derivative in Biological Fluids by HPLC (HPLC를 이용한 생체 시료중의 새로운 플라보노이드 유도체인 DA-6034의 분석)

  • Lee, Jong-Jin;Son, Mi-Won;Yoo, Moo-Hi;Jang, Min-Sun;Kim, Won-Bae;Lee, Kang-Chun
    • YAKHAK HOEJI
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    • v.42 no.2
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    • pp.149-152
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    • 1998
  • A high performance liquid chromatographic method was developed for the determination of DA-6034 in biological fluids using internal standard. Plasma containing DA-6034 and inter nal standard was extracted by liquid-liquid extraction at an acidic pH. After evaporation of the organic layer, the drug and internal standard were reconstituted with mobile phase and injected into the column. They were separated by high performance liquid chromatography on inertsil ODS II column at 334 nm. The detection limit of DA-6034 in plasma was 0.02 ${\mu}$g/ml. In this method, the range of recovery and coefficients of variation were 96-110% and 0.40-3.78%, respectively. There was no interference from endogenous substances. Urine and bile were analysed using the deproteinization method and the detection limit of DA-6034 was 1${\mu}$g/l.

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Aerodynamic Analysis on Wing-Nacelle of Tiltrotor UAV (틸트로터 무인기의 날개-나셀 공력해석)

  • Choi Seong Wook;Kim Cheol Wan;Kim Jai Moo
    • 한국전산유체공학회:학술대회논문집
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    • 2004.03a
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    • pp.27-34
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    • 2004
  • In the Smart UAV Development Program, one of the 21c Frontier R&D Program, the tiltrotor has been studied as the concept of vehicle. The tiltrortor aircraft take-off and land in rotary wing mode like conventional helicopter, and cruise in fixed wing mode like conventional propeller airplane. For the conversion of the flight mode from helicopter to airplane, the nacelle located at wing tip has to be tilted from about 90 degrees of helicopter mode to about 0 degree of airplane mode. In this study, the aerodynamic characteristics of the wing with tilted nacelle is investigated using computation fluid dynamics technique. In order to feature out aerodynamic interferences between wing and nacelle, the flow calculations are conducted for the wing and the nacelle separately and for the combined geometry of wing and nacelle, respectively. Through this computations, not only the aerodynamic data-base for the wing-nacelle is constructed but also its contribution to the configuration design of the wing-nacelle is anticipated.

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