• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.47 no.12
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• pp.831-840
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• 2019

Flush Air Data Sensing system (FADS) estimates air data states using pressure data measured at the surface of flight vehicles. The FADS system does not require intrusive probes, so it is suitable for high performance aircrafts, stealth vehicles, and hypersonic flight vehicles. In this study, calibration procedures and solution algorithms of the FADS for a sphere-cone shape vehicle are presented for the prediction of air data from subsonic to supersonic flights. Five flush pressure ports are arranged on the surface of nose section in order to measure surface pressure data. The algorithm selects the concept of separation for the prediction of flow angles and the prediction of pressure related variables, and it uses the pressure model which combines the potential flow solution for a subsonic flow with the modified Newtonian flow theory for a hypersonic flow. The CFD code which solves Euler equations is developed and used for the construction of calibration pressure data in the Mach number range of 0.5~3.0. Tests are conducted with various flight conditions for flight Mach numbers in the range of 0.6~3.0 and flow angles in the range of -10°~+10°. Air data such as angle of attack, angle of sideslip, Mach number, and freestream static pressure are predicted and their accuracies are analyzed by comparing predicted data with reference data.

• 한국지구물리탐사학회:학술대회논문집
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• 2008.10a
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• pp.107-112
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• 2008

In the case of the deep reservoirs like the gas reservoirs in the East-sea, it is often difficult to observe AVO responses in CMP gathers. Because the reservoir becomes more consolidated as its depth deepens, P-wave velocity does not decrease significantly when the pore fluid is replaced by the gas. In this study, we analyzed the effects of Poisson's ratio difference on AVO response with a variety of Poisson's ratios for the upper and lower layers. The results show that, as the difference in Poisson's ratio between the upper and lower layers decreases, the change in the reflection amplitude with incidence angle decreases. To consider the limitation of AVO responses shown in the gas reservoir in East-sea, the velocity model was made by simulation Gorae V structure with seismic data and well logs. The results of comparing AVO responses observed from the synthetic data with theoretical AVO responses calculated by using material properties show that the amount of the change in reflection amplitude with increasing incident angle is very small when the difference in Poisson's ratio between the upper and lower layers is small. In addition, the characteristics of AVO responses were concealed by noise or amplitude distortion arisen during preprocessing. To overcome such limitations of AVO analysis of the data from deep reservoirs, we need to acquire precisely reflection amplitudes in data acquisition stage and use processing tools which preserve reflection amplitude in data processing stage.

• Archives of Pharmacal Research
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• v.28 no.5
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• pp.604-611
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• 2005

Polyethylene glycol (PEG) 6000-based solid dispersions (SDs), by incorporating various pharmaceutical excipients or microemulsion systems, were prepared using a fusion method, t o compare the dissolution rates and bioavailabilities in rats. The amorphous structure of the drug in SDs was also characterized by powder X-ray diffractometry (XRD) and differential scanning calorimetry (DSC). The ketoconazole (KT), as an antifungal agent, was selected as a model drug. The dissolution rate of KT increased when solubilizing excipients were incorporated into the PEG-based SDs. When hydrophilic and lipophilic excipients were combined and incorporated into PEG-based SDs, a remarkable enhancement of the dissolution rate was observed. The PEG-based SDs, incorporating a self microemulsifying drug delivery system (SMEDDS) or microemulsion (ME), were also useful at improving the dissolution rate by forming a microemulsion or dispersible particles within the aqueous medium. However, due to the limited solubilization capacity, these PEG-based SDs showed dissolution rates, below 50% in this study, under sink conditions. The PEG-based SD, with no pharmaceutical excipients incorporated, increased the maximum plasma concentration (C$_{max}$) and area under the plasma concentration curve (AUC$_{0-6h}$) two-fold compared to the drug only. The bioavailability was more pronounced in the cases of solubilizing and microemulsifying PEG-based SDs. The thermograms of the PEG-based SDs showed the characteristic peak of the carrier matrix around 60$^{\circ}C$, without a drug peak, indicating that the drug had changed into an amorphous structure. The diffraction pattern of the pure drug showed the drug to be highly crystalline in nature, as indicated by numerous distinctive peaks. The lack of the numerous distinctive peaks of the drug in the PEG-based SDs demonstrated that a high concentration of the drug molecules was dissolved in the solid-state carrier matrix of the amorphous structure. The utilization of oils, fatty acid and surfactant, or their mixtures, in PEG-based SD could be a useful tool to enhance the dissolution and bioavailability of poorly water-soluble drugs by forming solubilizing and microemulsifying systems when exposed to gastrointestinal fluid.

• Nuclear Engineering and Technology
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• v.27 no.3
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• pp.301-316
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• 1995

experimental and computational studies ore carried out to investigate the natural convection of the single phase flow in a tank with a heated horizontal plate facing downward. This is a simplified model for investigations of the influence of a core melt at the bottom of a reactor vessel on the thermal hydraulic behavior in a oater filled cavity surrounding the vessel. In this case the vessel is simulated by a hexahedron insulated box with a heated plate Horizontally mounted at the bottom of the box. The box with the heated plate is installed in a water filled hexahedron tank. Coolers are immersed in the U-type water volume between the box and the tank. Although the multicomponent flows exist more probably below the heated plate in reality, present study concentrates on the single phase flow in a first step prior to investigating the complicated multicomponent thermal hydraulic phenomena. In the present study, in order to get a better understanding for the natural convection characteristics below the heated plate, the velocity and temperature are measured by LDA(Laser Doppler Anemometry) and thermocouples, respectively. And How fields are visualized by taking pictures of the How region with suspended particles. The results show the occurrence of a very effective circulation of the fluid in the whole How area as the heater and coolers are put into operation. In the remote region below the heated plate the new is nearly stagnant, and a remarkable temperature stratification can be observed with very thin thermal boundary. Analytical predictions using the FLUTAN code show a reasonable matching of the measured velocity fields.

• Korean Journal of Food Science and Technology
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• v.36 no.5
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• pp.779-783
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• 2004

New food ingredient was developed to eradicate and protect against re-infection of Helicobacter pylori in fermentation broth of lactic acid bacteria (LAB) showing antimicrobial activity against pathogenic microorganisms such as H. pylori and Listeria monocytogenes. LAB strain CBT SL4 was identified as Pediococcus pentosaceus by 16S rDNA sequencing and its culture broth showed antimicrobial activity of 800 AU/mL against H. pylori in optimized fermentation process. Using thin layer concentration system and spray-typed fluid bed drier system, concentrated powder product showing activity of 12,800 AU/g was harvested. Product showed eradication and protection activities against H. pylori infection on feeding test (50 AU/day) using Mongolian gerbil infection model. After 4 weeks therapy of 8,000 AU/day, ${\Delta}13CO_2$ level (DOB30) decreased about 40% in urea breath test on patient with H. pylori infection. Result show concentrated culture product of P. pentosaceus CBT SL4 has eradicating and protecting activities against H. pylori infection and can be used as food-active ingredient for prevention of gastric and duodenum ulcer caused by H. pylori.

• Journal of Advanced Marine Engineering and Technology
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• v.37 no.5
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• pp.500-509
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• 2013

This study reports a numerical analysis of the internal flow characteristics of the integrated urea-SCR muffler system with the various geometries of the multi-perforated tube which is set up between the muffler inlet and in front of SCR catalysts. The multi-perforated tube is generally used to disperse uniformly the urea-water solution spray and to make better use of the SCR catalyst, resulting in the increased $NO_x$ reduction and decreased ammonia slip. The effects of the multi-perforated tube orifice area ratios on the velocity distributions in front of the SCR catalyst, which is ultimately quantified as the uniformity index, were investigated for the optimal muffler system design. The steady flow model was applied by using a general-purpose commercial software package. The air at the room temperature was used as a working fluid, instead of the exhaust gas and urea-water solution spray mixture. From the analysis results, it was clarified that the multi-perforated tube geometry sensitively affected to the formation of the bulk swirling motion inside the plenum chamber set in front of the SCR catalyst and to the uniformity index of the velocity distribution produced at the inlet of the catalyst.

• Transactions of the KSME C: Technology and Education
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• v.3 no.1
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• pp.23-28
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• 2015

In this paper, we performed the design optimization dual-shell and tube heat exchanger on exhaust waste heat recovery for gas heat pump using CFD and RSM. CFD analysis is useful to design the complex structure such as double shell and tube heat exchanger. By computer simulation, engineers can assess the feasibility of the given design factors and change them to get a better design. But if one wishes to perform complex analysis on the simulation, such dual-shell and tube heat exchanger for GHP, the computational time can become overwhelming. CFD is powerful but it takes a lot of time for complex structure. Therefore, the CFD analysis is minimized by the optimization using the RSM method. As a result, the number of baffle and tube are optimized by 6 baffles and 25 tubes for heat transfer and flow friction. And then pressure drop and heat transfer is improved about 12.2%. We confirm the design optimization using CFD and RSM is useful on complex structure of heat exchanger.

• The Journal of the Acoustical Society of Korea
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• v.34 no.1
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• pp.36-45
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• 2015

Recently, a lot of studies have been made about the methods used to generate turbulent velocity fields stochastically in order to effectively predict broadband flow noise. Among them, the FRPM (Fast Random Particle Mesh) method which generates turbulence with specific statistical properties using turbulence kinetic energy and dissipation obtained from the steady solution of the RANS (Reynolds Averaged Navier-Stokes) equations has been successfully applied. However, the FRPM method cannot be applied to the flow noise problems involving intrinsic unsteady characteristics such as centrifugal fan. In this paper, to effectively predict the broadband noise generated by centrifugal fan, U-FRPM (unsteady FRPM) method is developed by extending the FRPM method to be combined with the unsteady numerical solutions of the unsteady RANS equations to generate the turbulence considered as broadband noise sources. Firstly, an unsteady flow field is obtained from the unsteady RANS equations through CFD (Computational Fluid Dynamics). Then, noise sources are generated using the U-FRPM method combined with acoustic analogy. Finally, the linear propagation model which is realized through BEM (Boundary Element Method) is combined with the generated sources to predict broadband noise at the listeners' position. The proposed technique is validated to compare its prediction result with the measured data.

• Restorative Dentistry and Endodontics
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• v.24 no.2
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• pp.330-336
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• 1999

In biological systems, the mineral that forms hard tissue is of an apatitic nature, and hydroxyapatite($Ca_5OH(PO_4)_3$: HA) is generally considered as the prototype for such a mineral. Thus, the precipitation of HA, having biological implications, has been the subject of several investigations. Crystal growth studies using HA seeds in supersaturated solutions have enhanced our understanding of the process and mechanism involved in seeded crystal growth. From these studies, it has become apparent that the precipitation rate of HA onto the seed crystals depends on the various conditions, especially on the additives. The relation between the supersaturated solution containing fluoride and the process of HA crystal growth enhances the understanding of mechanism of HA crystal growth. Until recently, the studies have been on the crystal growth of enamel minerals and synthetic HA seeds in the supersaturated solution containing 1~2 ppm fluoride. The purpose of the present investigation is to study the effect that fluoride of high concentration has on the crystal growth kinetics of HA. In order to produce the composition found in the secretory enamel fluid, experimental solutions of 1mM Ca, 3mM P, and 100mM Tris as background electrolyte were used. Then this experimental solutions were added to 0, 2, 4, 6, 8, 10 ppm fluoride. The effect of fluoride at high concentrations on the precipitation was examined in a bench-top crystal growth model adopting a miniaturized reaction column. Chemical analysis was employed for characterization of working solutions before and after the experimentation. Remarkable findings were : 1) the amount of crystal growth was gradually accelerated as the fluoride concentration increased until 6 ppm, but decreased in 8 and 10 ppm fluoride; 2) the amount of fluoride ion consumed in crystal formation was constant despite the increase in fluoride concentration.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.29 no.2
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• pp.92-108
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• 2017

Present work shows a numerical method to analysis of interaction analysis between solitary wave and onshore bridge. Numerical simulation is carried out by TWOPM-3D (three-dimensional one-field model for immiscible two-phase flows), which is based on Navier-Stokes solver. To do this, the solitary wave is generated numerically in numerical wave channel, and numerical results and experimental results were compared and analyzed in order to verify the applicability of force acting on an onshore bridge. From this, we discussed precisely the characteristics of horizontal and vertical forces (uplift and downward forces) changes including water level and velocity changes due to the variation of solitary wave height, water depth, onshore bridge's location and type, and number of girder. Furthermore, It is revealed that the maximum horizontal and vertical forces acting on the girder bridge show different varying properties according to the number of girder, although each maximum force acting on the girder bridge is proportional to the increasement of incident solitary wave height, and the entrained air in the fluid flow affects the vertical force highly.