• Title/Summary/Keyword: Fluid Management

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Microbiological and clinical effects of enamel matrix derivative and sustained-release micro-spherical minocycline application as an adjunct to non-surgical therapy in peri-implant mucosal inflammation

  • Faramarzi, Masumeh;Goharfar, Zahra;Pourabbas, Reza;Kashefimehr, Atabak;Shirmohmmadi, Adileh
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.41 no.4
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    • pp.181-189
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    • 2015
  • Objectives: The purpose of this study was to compare the microbial and clinical effects of mechanical debridement (MD) alone or in combination with the application of enamel matrix derivative (EMD) and sustained-release micro-spherical minocycline (MSM) for treatment of peri-implant mucosal inflammation (PIMI). Materials and Methods: Subjects with at least one implant with PIMI were included and divided into control and two different test groups. In all three groups, MD was performed. In the MSM group, following MD, MSM was placed subgingivally around the implants. In the EMD group, after MD, EMD was placed in the sulcus around the implants. Sampling of peri-implant crevicular fluid for microbial analysis with real-time polymerase chain reaction and recording of probing depth (PD) and bleeding on probing (BOP) were performed prior to as well as two weeks and three months after treatment. Median values and interquartile range were estimated for each variable during the various assessment intervals of the study. Results: In all groups, at two weeks and three months, the counts of Porphyromonas gingivalis decreased significantly compared to baseline. Levels of P. gingivalis were significantly reduced in MSM (P<0.001) and EMD (P=0.026) groups compared to the control group. Also, clinical parameters improved significantly at two weeks and three months. Reduction of PD was significant in MSM (P<0.001) and EMD (P<0.001) groups. The decrease in BOP in the MSM, EMD, and control groups was 60%, 50%, and 20%, respectively. Conclusion: The use of MSM and EMD can be an adjunctive treatment for management of PIMI and improves clinical parameters and reduces P. gingivalis burden three months after treatment.

Correlation of Dehydration with Body Mass Index and Blood Lipid Levels (탈수와 체질량지수 및 혈중지질 농도와의 관련성)

  • Kim, Sun-Hee;Yun, Mi-Eun;Yoo, Jae-Hyun;Chun, Sung-Soo
    • Journal of the Korean Dietetic Association
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    • v.23 no.1
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    • pp.27-38
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    • 2017
  • Maintaining adequate fluid balance is essential for all biological functions in the body. The purpose of this study was to evaluate vulnerability to dehydration by analyzing age, gender, body mass index (BMI), and blood lipid parameters in health checkup examinees who visited Sahmyook Seoul Hospital for comprehensive health checkups. In a binary logistic regression analysis stratified by age and body mass index the odd ratio for dehydration was as high as 3.317 (95% CI: 1.666~6.605) in the 50s age group, 4.224 (95% CI: 2.038~ 8.755) in the 60s age group, and 4.610 (95% CI: 1.943~10.940) in the above 70s age group compared to 20s reference age group. Aged females showed greater vulnerability to dehydration with significance levels of P<0.01 and P<0.001. Compared to a normal weight (BMI: 18.5~22.9) the odd ratio was higher in males with an under weight (BMI: less than 18.5) (5.130 [95% CI: 1.631~16.132]) and in females with an over weight (BMI: 23.0~24.9) (1.500 [95% CI: 1.065~2.114]). In conclusion, our results showed that vulnerability to dehydration increased with age and was higher in under weight males and over weight females than that in normal weight.

Wind profile management and blockage assessment for a new 12-fan Wall of Wind facility at FIU

  • Aly, Aly Mousaad;Chowdhury, Arindam Gan;Bitsuamlak, Girma
    • Wind and Structures
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    • v.14 no.4
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    • pp.285-300
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    • 2011
  • Researchers at the International Hurricane Research Center (IHRC), Florida International University (FIU), are working in stages on the construction of a large state-of-the-art Wall of Wind (WoW) facility to support research in the area of Wind Engineering. In this paper, the challenges of simulating hurricane winds for the WoW are presented and investigated based on a scale model study. Three wind profiles were simulated using airfoils, and/or adjustable planks mechanism with and without grids. Evaluations of flow characteristics were performed in order to enhance the WoW's flow simulation capabilities. Characteristics of the simulated wind fields are compared to the results obtained from a study using computational fluid dynamics (CFD) and also validated via pressure measurements on small-scale models of the Silsoe cube building. Optimal scale of the test model and its optimal distance from the WoW contraction exit are determined - which are two important aspects for testing using an open jet facility such as the WoW. The main objective of this study is to further the understanding of the WoW capabilities and the characteristics of its test section by means of intensive tests and validations at small scale in order to apply this knowledge to the design of the full-scale WoW and for future wind engineering testing.

Application of EFDC and WASP7 in Series for Water Quality Modeling of the Yongdam Lake, Korea

  • Seo, Dong-Il;Kim, Min-Ae
    • Journal of Korea Water Resources Association
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    • v.44 no.6
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    • pp.439-447
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    • 2011
  • This study aims to test the feasibility of combined use of EFDC (Environmental Fluid Dynamics Code) hydrodynamic model and WASP7.3 (Water Quality Analysis Program) model to improve accuracy of water quality predictions of the Yongdam Lake, Korea. The orthogonal curvilinear grid system was used for EFDC model to represent riverine shape of the study area. Relationship between volume, surface and elevation results were checked to verify if the grid system represents morphology of the lake properly. Monthly average boundary water quality conditions were estimated using the monthly monitored water quality data from Korean Ministry of Environment DB system. Monthly tributary flow rates were back-routed using dam discharge data and allocated in proportion to each basin area as direct measurements were not available. The optimum number of grid system was determined to be 372 horizontal cells and 10 vertical layers of the site for 1 year simulation of hydrodynamics and water quality out of iterative trials. Monthly observed BOD, TN, TP and Chl-a concentrations inside the lake were used for calibration of WASP7.3 model. This study shows that EFDC and WASP can be used in series successfully to improve accuracy in water quality modeling. However, it was observed that the amount of data to develop inflow water quality and flow rate boundary conditions and water quality data inside lake for calibration were not enough for accurate modeling. It is suggested that object-oriented data collection systems would be necessary to ensure accuracy of EFDC-WASP model application and thus for efficient lake water quality management strategy development.

Literary investigation on the origin of poppy and other narcotics Research Articles (아편 유래 약물에 대한 문헌적 고찰)

  • Lim, Chung-San;Han, Young-Ju;Kang, Kye-Sung;Lee, Kwang-Ho;Kim, Doo-Young;Kwon, Ki-Rok
    • Journal of Pharmacopuncture
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    • v.12 no.2
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    • pp.67-75
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    • 2009
  • Objectives : This study was performed to developing orally administered analgesics and locally injected pharmacopuncture analgesics like opioids. Methods : Literary investigation on the origin of poppy (Papaver somniferum L) and other narcotics was conducted to examine the potential of developing orally administered analgesics and locally injected pharmacopuncture analgesics. Opium is a gum-like mass derived from air-dried white fluid of immature fruit of the poppy. Opium contains approximately 20 types of alkaloids including morphine, codeine, thebaine, papaverine and others. Natural opioids and synthetic alkaloid derivatives are the constituents of opioid analgesics and their effects and side-effects depend on the peculiarities of receptors. An extreme caution is required in the selection of proper dosage, proper analgesic types, and indications for successful pain management. Results and Discussion : With the enactment of "Narcotic control protocol", herbs such as cannibis and poppy are no longer available for use by Korean medicine doctors, and these doctors are faced with difficulty in managing severe pain in the clinical environment. A systematic consideration is inevitable for overcoming the limitation on these analgesics.

A Numerical Study on Performance Improvement of Canopy Hood in Melting Process (용해공정의 캐노피 후드 성능 개선에 관한 수치 해석적 연구)

  • Jung, Yu-Jin;Shon, Byung-Hyun;Lee, Sang-Man;Jung, Jong-Hyeon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.3
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    • pp.1519-1526
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    • 2013
  • This study reviewed the capturing performance of a canopy hood used in some melting processes of a casting manufacturing factory through a site survey. In addition, this study compared and evaluated the flow field and pressure field for the plans to enhance the hazardous air pollutants collection capacity by using CFD model. The case-2(flange attached + double hood) can be improved in terms of collection performance, but is expected to increase in hood static pressure by about 70% more than the existing structure, so it was shown that its site applicability is not good. It is judged that the shape of case-3(flange attached + double cone attached) is most suitable to improve the suction efficiency. This is because a double cone is installed at the center of the opening to concentrate the flow rate on the edge of the hood and control the hume rising to the center of the hood without a static pressure rise via the slope of the cone.

Heat Exchanger Ranking Program Using Genetic Algorithm and ε-NTU Method for Optimal Design (유전알고리즘과 ε-NTU 모델을 이용한 다양한 열교환기의 최적설계 및 성능해석)

  • Lee, Soon Ho;Kim, Minsung;Ha, Man Yeong;Park, Sang-Hu;Min, June Kee
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.38 no.11
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    • pp.925-933
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    • 2014
  • Today, computational fluid dynamics (CFD) is widely used in industry because of the availability of high-performance computers. However, full-scale analysis poses problems owing to the limited resources and time. In this study, the performance and optimal size of a heat exchanger were calculated using the effectiveness-number of transfer units (${\varepsilon}-NTU$) method and a database of characteristics heat exchanger. Information about the geometry and performance of various heat exchangers is collected, and the performance of the heat exchanger is calculated under the given operating conditions. To determine the optimal size of the heat exchanger, a Genetic Algorithm (GA) is used, and MATLAB and REFPROP are used for the calculation.

Development of Power Distribution Control Strategy for Plug-in Hybrid Electric Vehicle using Neural Network (인공신경망을 이용한 플러그인 하이브리드 차량의 동력분배제어전략 개발)

  • Sim, K.H.;Lee, S.J.;Lee, J.S.;Namkoong, C.;Han, K.S.;Hwang, S.H.
    • Journal of Drive and Control
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    • v.12 no.3
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    • pp.18-24
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    • 2015
  • The plug-in hybrid electric vehicle has a high fuel economy and can be driven long distances. Its different modes include the electric vehicle, hybrid electric vehicle, and only engine operating mode. A power management strategy is important to determine which mode should be selected. The strategy makes the vehicle more efficient using appropriate power sources for driving. However, the strategy usually needs a driving speed profile which is future driving cycle. If the profile is known, the strategy easily determines which mode is driven efficiently. However, it is difficult to estimate the speed profile for a real system. To address this problem, this paper proposes a new power distribution strategy using a neural network. The average speed and driving range are used as input parameters to train the neural network system. The strategy determines a limit for the use of the battery and the desired power is distributed between the engine and the motor simultaneously. Its fuel economy can increase by improving the basic strategy.

A Case Study of Taeeumin Patient with Edema Treated with Gunyuljejo-tang (태음인 부종 환자의 건율제조탕 치험 1례)

  • Han, Suzy;Yu, Jun-Sang
    • Journal of Sasang Constitutional Medicine
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    • v.33 no.3
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    • pp.138-145
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    • 2021
  • Objectives Edema occurs in various disorders, such as heart failure, nephrotic syndrome, renal failure, liver cirrhosis, and cancer. The excessive accumulation of interstitial fluid in limb tissue will often manifest with ankle and knee swelling and lowers patient's quality of life. But the conventional treatment includes restricting dietary sodium and using diuretics. The purpose of this study is about significant improvement of a patient with edema who had suffered from dependent gait accompanied by mild pain, after treatment by herbal medicine based on SCM(Sasang constitutional medicine). Methods The pattern identification of the patient was diagnosed with a superficial disease of Taeeumin. So after the admission, Gunyuljejo-tang was used, almost two times per day during 2 weeks. Also, we applied acupuncture routinely every day and western medicine as needed. We measured the circumferences of Lt. thigh and followed up the bioelectrical impedance analysis and checked the appearance of lower limb. Results and Conclusions The therapy was effective, and the circumferences, which was 59.69cm at onset time, decreased to 52.07cm almost same to the healthy side of her thigh. There was no more edematous sign on the body, either. This case showed that management of Taeeumin's healthy energy(呼散之氣, the energy of exhalation) could be effective in treating edema.

A Study on the Buddhist Contents in the Bencaoshengyabanji (『본초승아반게(本草乘雅半偈)』의 불교(佛敎) 관련 설명에 대한 고찰)

  • Ahn, Jinhee;Yun, Ki-ryoung;Nan, Jie
    • Journal of Korean Medical classics
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    • v.34 no.4
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    • pp.27-64
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    • 2021
  • Objectives : This paper examined the Buddhist contents within the text, Bencaoshengyabanji(本草乘雅半偈). Methods : Medicinals that were searched through Buddhist vocabulary were examined. Results & Conclusions : Medicinals that quoted the Lengyanjing were related to the Water-Fire interaction, food and medicine, and karma, while those that quoted the Shidian were related to 無上道, 去惡殺蟲, 樞機滑利, and 生生之氣. Those related to the Great Earth of the Four Elements corrected the body's form based on Metal Qi, while those related to the Great Water were connected to the circulation of water dampness. Those related to the Great Fire were deeply related to Yang Qi, and those related to the Great Wind were connected to Wind control. Of the Four Origins, medicinals that were viviparous lowered Qi, while those that were oviparous were related to communicating Shen, treating diseases of the Conception Vessel, and the closing and opening of day and night. Medicinals originating from dampness were related to urination and fluid management, while those of metamorphosis were related to the process of Qi. Those related to emptiness were related to the communication of the Qi system, while those related to 六根六塵 were connected to calming the Shen and strengthening the will, and smoothing the nine orifices. Medicinals related to 圓通 were used for improving eyesight and hearing and controlling the closing and opening. Lu Zhi-yi's analysis of medicinals through the Lengyanjing is original in that it suggested a new perspective other than previous theories on pharmacology which were based on the Yin-Yang and Five Phases and Rising/Lowering/Floating/Sinking theories, but also pedantic and exaggerated. The Bencaoshengyabanji is a unique text on medicinals which analyzed each medicinal under Buddhist influence. However, it also followed the contexts of other previous texts on medicinals, and influenced Zou shu.