• Journal of the Korean Chemical Society
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• v.63 no.6
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• pp.427-434
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• 2019

The role of hydrophobic residues on protein folding reaction was studied by folding kinetics measurements in conjunction with protein engineering. The HubWA, which was derived from human ubiquitin by mutating the residues at 45 (Phe to Trp) and 26 (Val to Ala), was used as a mutational background. Fourteen hydrophobic residues were mutated to alanine. Among fourteen variants generated, only four variant proteins (V5A, I13A, V17A, and I36A) were suitable for folding study. The folding kinetics of these variants was measured by stopped-flow fluorescence spectroscopy. The folding kinetics of HubWA and V17A was observed to follow a three-state on-pathway mechanism. On the other hand, folding kinetics of V5A, I13A, and I36A was observed to follow a two-state mechanism. Based on these observations, transition of protein folding reaction from collision-diffusion mechanism to nucleation-condensation mechanism was discussed.

• Journal of Institute of Control, Robotics and Systems
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• v.22 no.3
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• pp.210-216
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• 2016

This paper presents a novel collision avoidance technique for mobile robots based on omni-directional vision simultaneous localization and mapping (SLAM). This method estimates the avoidance path and speed of a robot from the location of an obstacle, which can be detected using the Lucas-Kanade Optical Flow in images obtained through fish-eye cameras mounted on the robots. The conventional methods suggest avoidance paths by constructing an arbitrary force field around the obstacle found in the complete map obtained through the SLAM. Robots can also avoid obstacles by using the speed command based on the robot modeling and curved movement path of the robot. The recent research has been improved by optimizing the algorithm for the actual robot. However, research related to a robot using omni-directional vision SLAM to acquire around information at once has been comparatively less studied. The robot with the proposed algorithm avoids obstacles according to the estimated avoidance path based on the map obtained through an omni-directional vision SLAM using a fisheye image, and returns to the original path. In particular, it avoids the obstacles with various speed and direction using acceleration components based on motion information obtained by analyzing around the obstacles. The experimental results confirm the reliability of an avoidance algorithm through comparison between position obtained by the proposed algorithm and the real position collected while avoiding the obstacles.

• Journal of Korea Water Resources Association
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• v.54 no.6
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• pp.407-418
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• 2021

In this study, the two-dimensional flow model, Nays2DH, and driftwood dynamics model were combined to analyze the flow and driftwood behavior depending on the characteristics of the inflow of driftwood and the length of the driftwood stem. In particular, the Dashpot-spring model was added to the driftwood dynamics model to simulate the collision motion of the driftwood, and the wood jam characteristics by the collision of the driftwood were compared. As a result of the simulation, the pass rate of the obstacle section, the travel distance of wood jam, and the mean position of the wood pieces were respondent sensitively by the length of the driftwood stem, but the cohort size of the driftwood supply was insignificant excepting for the pass rate. Through this study, we could understand the interaction between hydraulic structures and driftwood, and through this, it is believed that it will be helpful in establishing a durable maintenance plan for hydraulic structures by predicting the transport and jam formation phenomena of driftwood in advance.

• Journal of Korean Society of Transportation
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• v.29 no.3
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• pp.73-82
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• 2011

Recent advancement in traffic surveillance systems has allowed the researchers to obtain more detailed vehicular movement such as individual vehicle trajectory data. Understanding the characteristics of interactions between leading and following vehicles in the traffic flow stream is a backbone for designing and evaluating more sophisticated traffic and vehicle control strategies. This study proposes a methodology for estimating rear-end crash potential, as a probabilistic measure, in real-time based on the analysis of vehicular movements. The methodology presented in this study consists of three components. The first predicts vehicle position and speed every second using a Kalman filtering technique. The second estimates the probability for the vehicle's trajectory to belong to either 'changing lane' or 'going straight'. A binary logistic regression (BLR) is used to model the lane-changing decision of the subject vehicle. The other component calculates crash probability by employing an exponential decay function that uses time-to-collision (TTC) between the subject vehicle and the front vehicle. The result of this study is expected to be adapted in developing traffic control and information systems, in particular, for crash prevention.

• 한국전산유체공학회:학술대회논문집
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• 2005.10a
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• pp.11-19
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• 2005

First, methods of numerical analysis of gas-particle flows is classified into micro, meso and macro scale approaches based on the concept of multi-scale mechanics. Next, the explanation moves on to discrete particle simulation where motion of individual particles is calculated numerically using the Newtonian equations of motion. The author focuses on the cases where particle-to-particle interaction has significant effects on the phenomena. Concerning the particle-to-particle interaction, two cases are considered: the one is collision-dominated flows and the other is the contact-dominated flows. To treat this interaction mathematically, techniques named DEM(Distinct Element Method) or DSMC (Direct Simulation Monte Carlo) have been developed DEM, which has been developed in the field of soil mechanics, is useful for the contact -dominated flows and DSMC method, developed in molecular gas flows, is for the collision-dominated flows. Combining DEM or DSMC with CFD (computer fluid dynamics), the discrete particle simulation becomes a more practical tool for industrial flows because not only the particle-particle interaction but particle-fluid interaction can be handled. As examples of simulations, various results are shown, such as hopper flows, particle segregation phenomena, particle mixing in a rotating drum, dense phase pneumatic conveying, spouted bed, dense phase fluidized bed, fast circulating fluidized bed and so on.

• Wind and Structures
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• v.23 no.6
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• pp.523-542
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• 2016

Snowdrift formation on roofs should be considered in snowy and windy areas to ensure the safety of buildings. Presently, the prediction of snowdrifts on roofs relies heavily on field measurements, wind tunnel tests and numerical simulations. In this paper, a new snowdrift modeling method by using CFD (Computational Fluid Dynamics) coupled with DEM (Discrete Element Method) is presented, including material parameters and particle size, collision parameters, particle numbers and input modes, boundary conditions of CFD, simulation time and inlet velocity, and coupling calculation process. Not only is the two-way coupling between wind and snow particles which includes the transient changes in snow surface topography, but also the cohesion and collision between snow particles are taken into account. The numerical method is applied to simulate the snowdrift on a typical stepped flat roof. The feasibility of using coupled CFD with DEM to study snowdrift is verified by comparing the simulation results with field measurement results on the snow depth distribution of the lower roof.

• Journal of the Society of Naval Architects of Korea
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• v.54 no.1
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• pp.26-33
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• 2017

In this study, the surface marker method, one of the particle tracking methods, used to track the free surface is extended to cover the more general cases easily including the collision and separation of the free surface. In surface particle method to redistribute particles effectively using the grid system, the free surface is composed of the sum of quadrilaterals having four curves where fixed markers are placed at ends of each curve. Fixed markers are used to know how curves are connected to each other. The position of fixed markers can move as the free surface deforms but all fixed markers cannot be deleted during all time of simulation to keep informations of curve connection. In the case of the collision or separtion of the free surface where several curves can be intersected disorderly, severe difficulties can occur to define newly states of curve connection. In this study, the adaptable surface parTicle method without fixed markers is introduced. Intersection markers instead of the fixed markers are used to define quadrilaterals. The position of the intersection markers is defined to be the intersection point between the free surface and the edge of the grid and it can be added or deleted during the time of simulation to allow more flexibilities. To verify numerical schemes, two flow cases are simulated and the numerical results are compared with other's one and shown to be valid.

• Transactions of the Korean Society of Automotive Engineers
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• v.19 no.6
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• pp.61-67
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• 2011

The cooling module needs enough space (or distance) from hood to absorb the energy from any pedestrian collision. Downsized cooling module for pedestrian protection is important to reduce the severity of pedestrian injury. When a vehicle collision happens, the downsized cooling module is required to reduce the risk of injury to the upper legs of adults and the heads of children. In this study, the performance of cooling module to cool the engine was investigated under 25% height reduction. The heat dissipation and pressure drop characteristics have been experimentally studied with the variation of coolant flow rate, air inlet velocity and A/C operation ON/OFF for the downsized cooling module. The results indicated that the cooling performance was about 94% level compared to that of the conventional cooling module. Therefore, we checked that the cooling module had good performance, and expected that the cooling module could meet the same cooling performance as conventional cooling module through optimization of components efficiency.

• Journal of Korean Society of Water and Wastewater
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• v.18 no.2
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• pp.235-241
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• 2004

The dissolved air flotation (DAF) process has been widely used for removing suspended solids with low density in water. It has been known as measuring the size of microbubbles precisely which move upward rapidly in contact zone is difficult. In this study particle counter monitoring (PCM) method is used to measure the rising microbubble after injection from a nozzle. Size and distribution curve of microbubbles are evaluated at different conditions such as pressure drop at intermediate valve, length of pipeline between saturation tank and nozzle and low pressure. And the efficiency is also checked when it collides with different size floc. The experimental results show the following fact. As the final pressure drop occurred closer to a nozzle, the bubble size became smaller. And small bubble collides with large floc as well as small one because of its physical characteristic. However large bubble collides well with large floc rather than small one since hydrodynamic flow in streamline interferes to collide between two. With performing computational process by mathematical model we have analyzed and verified the size effect between bubble and floc. Collision efficiency is the highest when P/B ratio shows in the range of 0.75 < P/B ratio ($R_{particle/Rbubble}$) < 2.0.

• Journal of the Korean Institute of Intelligent Systems
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• v.24 no.6
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• pp.603-608
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• 2014

In the maritime traffic environment, the near-miss between vessels is the situation approaching on collision course but collision accident is not occurred. In this study, in order to calculate the near-miss between navigating vessels, the discriminating equation using ship bumper theory and vessel position clustering methods are proposed. Applying proposed module to the vessel trajectories of the WANDO waterway, we assessment navigational risk factors of vessel type, navigational speed, meeting situation.