• 제목/요약/키워드: Flavonoid glycoside

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Antioxidative Properties of Ginseng Leaf Flavonoids on Cellular Membranes

  • Park, Soo-Nam;San
    • 대한화장품학회지
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    • 제16권1호
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    • pp.1-17
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    • 1990
  • The major flavonoid component of Ginseng leaf is trifolin, a glycoside of kaempferol. To evaluate the antioxidative properties of trifolin and kaempferol on cellular membranes, we compared them with the other flavonoids through the 102-Induced photohemolysis of rabbit erythrocytes. All the flavonoid aglycones including kaempferol, quercetin and baicalein protected effectively the cells from the 102-caused damage in a dose- dependent manner, by scavenging 102 and free radicals in the cellular membranes. The solubilization of the flavonoid aglycones into micelles or erythrocyte membranes was deduced from spectro-photometric and microscopic observations. The flavonoid glycosides were not protective or less protective than their corresponding aglycones, and trifolin was the only glycoside that exhibited a solubilization into the membranes and a significant protection against the photohemolysis. We also tested some phenolic compounds contained in Ginseng, and found that they did not prevent the photohemolysis so effectively as kaempferol or trifolin.

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한국산 닭의덩굴속 호장근절(마디풀과)의 화학분류학적 연구 (Flavonoid chemistry of Fallopia sect. Reynoutria (Polygonaceae) in Korea)

  • 박진희;문혜경;박종욱
    • 식물분류학회지
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    • 제41권1호
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    • pp.10-15
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    • 2011
  • 본 연구에서는 한국산 닭의덩굴속 호장근절 분류군들을 대상으로 개체군 수준에서 flavonoid 분석을 수행하여, 본 절 분류군에서 나타나는 형태변이 양상을 화학적 측면에서 파악하고, 이를 토대로 한반도에 분포하는 본 절 분류군들의 실체 및 한계를 정확히 파악하고자 하였다. 그 결과, 한국산 본 절 3분류군 15개체군의 잎으로부터 19종류의 서로 다른 flavonoid compound가 분리, 동정되었으며, 이들은 flavonol인 quercetin 및 kaempferol 3-O-glycoside들과 flavone인 apigenin및 luteolin C-glycoside들이었다. 이들 compound들 중 한국산 본 절 식물에 분포하는 주요 flavonoid compound는 quercetin 3-O-galactoside 와 quercetin 3-O-glucoside이었다. 본 절 한국산 분류군들은 그 flavonoid 조성에 의해 뚜렷이 구분되는 것으로 밝혀졌으며, 이러한 결과는 기존의 외부 형태학적 연구 결과와 전반적으로 일치하였다. 한편, 잡종으로 추정되는 논산 개체군의 flavonoid 조성은 F. japonica var. japonica, F. forbesii 및 F. sachalinensis와 일부 compound를 공유하는 것으로 나타났다. Fallopia japonica var. japonica의 경우, 염색체수 배수화에 따른 flavonoid 조성의 정성적 차이는 발견할 수 없었으나, 지리적 변이가 일부 나타나는 것으로 밝혀졌다.

금강제비꽃 잎의 Flavonoid 배당체(II) (Studies on Flavonoid Glycoside of the leaves of Viola diamantica)

  • 육창수;이우철;문창규
    • 약학회지
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    • 제33권2호
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    • pp.124-128
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    • 1989
  • The drug consists of the dried entire plant of Viola diamantica (family Violaceae). It is used for the treatment of acute pyogenic diseases such as boil and carbuncles; also as tumor, high fever, tuberculosis and astringent hemostatic. Two flavonol glycosides have been isolated from the aerial parts of Viola diamantica and could be identifed as kaempferol 7-rhamnoside and kaempferol 3,7-dirhamnoside (bright yellow needle crystal, mp $225^{\circ}$, $C_{27}\;H_{30}\;O_4\;4H_2O$). Kaempferol 7-rhamnoside and kaempferol 3,7-dirhamnoside were first isolated from Viola diamantica.

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Flavanone Glycoside from the Fruits of Chaenomeles sinensis

  • Kim, Ho-Kyoung;Jeon, Won-Kyung;Ko, Byoung-Seob
    • Natural Product Sciences
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    • 제6권2호
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    • pp.79-81
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    • 2000
  • Investigation of the fruits of Chaenomeles sinensis (Rosaceae) resulted in the isolation of a minor flavonoid. The structure of flavanone glycoside was determined to be as $2-hydroxynaringenin-7-O-{\beta}-glucoside$ on the basis of FAB-MS and spectral evidence, especially by 2D-NMR $(^1H-^1H\;COSY,\;HMQC,\;HMBC\;and\;NOESY)$.

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지실의 생리활성성분 (Biological Active Components of Fruits of Poncirus trifoliata)

  • 윤황금;김동현;김남재;홍남두
    • 약학회지
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    • 제36권6호
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    • pp.548-555
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    • 1992
  • The biological activities of fruits of Poncirus trifoliata have been studied. 70% Ethanol extract of Ponciri Fructus was fractionated with ether, ethyl acetate and n-butanol by turns. The ether fraction showed antibacterial activity on Staphylococcus aureus and inhibited the contractability of the isolated mice ileum. The ethyl acetate and n-butanol fractions showed the anti-edematous effect on the carrageenin-induced edema of rat hindpaw. From the n-butanol fraction, one of the flavonoid glycoside was isolated and identified as poncirin. Ponciri Fructus contained about 6% poncirin which was 5,7-dihydroxy-4´-methoxy flavanone rhamnoglucoside and poncirin showed antiinflammatory activities. Poncirin was considered as the major effective component of Ponciri Fructus.

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Flavonoid Glycosides from Melandrium firmum

  • Woo, Eun-Hee;Woo, Won-Sick
    • Archives of Pharmacal Research
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    • 제12권3호
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    • pp.223-225
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    • 1989
  • Linarin and schaftoside were isolated from Melandrium firmum (Caryophyllaceae) and characterized by spectral data.

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Flavonoids from Leaves and Exocarps of the Grape Kyoho

  • Park, Hye-Jeong;Cha, Hyeon-Cheol
    • Animal cells and systems
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    • 제7권4호
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    • pp.327-330
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    • 2003
  • We analyzed and compared profiles of flavonols extracted from leaves and exocarps of the grape Kyoho by TLC, HPLC and UV spectrophotometry. In the exocarps, quercetin 3-O-glucoside was the main compound while isorhamnetin 3-O-glycoside (I) was present in minor amounts. In leaves, on the other hand, quercetin 3-O-glucoside and quercetin 3-O-glucoside-7-O-glucronide were the major compounds while isorhamnetin 3-O-glycoside (II) and kaempferol 3, 7-O-diglycoside were present in minor amounts.