• Journal of Korea Water Resources Association
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• v.41 no.1
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• pp.75-85
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• 2008

The pale chub (Zacco platypus) is a dominant species that migrates locally and inhabits in rivers in Korea. The fish movement at confluences or hydraulic connections is very important especially for the life of small fish as pale chub. If main stream and off-channel habitats are connected with culverts, they would restrict the fish movement due to the high flow velocities and low depths. In foreign conturies, design flow conditions of fish friendly culvert, including flood flow capacity and fish-passage flow capacity, were assigned. Installation of culvert fishways is one way to improve the fish-passing capacity of culverts. On the contrary, in Korea, the design flow of culvert contains only the flood flow capacity. The effect of the fish passage with offset baffles was tested with the fixed velocity method in an experimental flume. As a result, An occasion velocity 1.2m/s, proportional success of pale chubs pass is maximum 20% improve than without baffle flume for energy dissipate. Offset baffle fishway(baffle height 5cm) provides that resting areas and/or a continuous channel of low velocity water in culverts. Especially, short baffle areas are domain where the pale chubs pass. And, FLOW-3D, a three dimentional numerical model, was used in order to evaluate detailed hydraulic characteristics and application possibility in a culvert fishway design.

• Journal of Biomedical Engineering Research
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• v.19 no.6
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• pp.551-562
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• 1998

Amultiresolution filtering algorithm based on the physical SPECT lesion detachability provides and optimal solution for SPECT reconstruction problem. Related to the previous study, we estimated the SPECT lesion detection capability by m minimum detectable lesion sizes (MDLSs), and generated m reconstruction filters which are designed to maximize the smoothing effect at a fixed MDLS-dependent resolution level $\frac{MDLS}{4\sqrt{2In2}}$. The proposed multiresolution filtering algorithm used a coarse-to-fine approach for the m-level resolution filter images obtained from these m filters for a given projection image. First, the local homogeneity is determined for every pixel of the filter images, by comparing the local variance value computed in a window centered at the pixel and the mode determined from the distribution of the local variances. Based on the local homogeneity, the pixels declared as homogeneous are chosen from the filter image of the lowest resolution, and for the other pixels the same process is repeated for the higher resolution filter images. For the non-homogeneous pixels after this pixels after this repetition process ends, the pixel values of the highest resolution filter image are substituted. From the results of the simulated experiments, the proposed multiresolution filtering algorithm showed a strong smoothing effect in the homogeneous regions and a significant resolution improvement near the edge regions of the projection images, and so produced good adaptability effects in the reconstructed images.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.1
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• pp.714-721
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• 2018

In this study, we investigate a design technology intended to radically increase the buckling strength of vertically curved panels. Recent studies proposed a buckling strength formula which properly reflects the effect on the local plate buckling strength of flat plates when they are stiffened by closed section ribs. Herein, we attempted to quantitatively evaluate this effect on curved panels and to reveal the correlations with the design parameters. The commercial finite element software, ABAQUS, was used to build a three dimensional numerical model and numerical parametric studies were conducted to evaluate the variation of the buckling strength. In the case of flat panels, the local buckling strength of stiffened curved panels increases proportionally with increasing rotational stiffness of the closed-section ribs. After attaining a limiting value, an obvious tendency was found that the local buckling strength of the stiffened curved panel would converge towards a fixed value when the panels are supported along both sides. The parametric studies performed using the influential design parameters confirmed that the estimated partially-restrained curved panel strength is well correlated with the proposed formula.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.7
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• pp.2953-2958
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• 2015

Although associations between thioredoxin interacting protein (TXNIP) and cancers have been recognized, the effects of TXNIP on non-small cell lung cancer (NSCLC) prognosis remained to be determined in detail. In addition, while hypoxia is a key characteristic of tumor cell growth microenvironment, the effect of hypoxia on TXNIP expression is controversial. In this study, formaldehyde fixed and paraffin embedded (FFPE) samples of 70 NSCLC patients who underwent resection between January 2010 and December 2011 were obtained. Evaluation of TXNIP and hypoxia inducible factor-$1{\alpha}$ ($HIF-1{\alpha}$) protein expression in FFPE samples was made by immunohistochemistry. By Kaplan-Meier method, patients with high TXNIP expression demonstrated a significantly shorter progression free survival (PFS) compared with those with low TXNIP expression (18.0 months, 95%CI: 11.7, 24.3 versus 23.0 months, 95%CI: 17.6, 28.4, P=0.02). High TXNIP expression level was also identified as an independent prognostic factor by Cox regression analysis (adjusted hazard ratio: 2.46; 95%CI: 1.08, 5.56; P=0.03). Furthermore, TXNIP expression was found to be significantly correlated with $HIF-1{\alpha}$ expression (Spearman correlation=0.67, P=0.000). To further confirm correlations, we established a tumor cell hypoxic culture model. Expression of TXNIP was up-regulated in all three NSCLC cell lines (A549, SPC-A1, and H1299) under hypoxic conditions. This study suggests that hypoxia induces increased TXNIP expression in NSCLC and high TXNIP expression could be a poor prognostic marker.

• Transactions of the Korean Society of Mechanical Engineers
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• v.16 no.4
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• pp.737-752
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• 1992

Analysis of elasto-dynamic deformation of flexible linkage mechanism is conducted using the finite element method. The equations of motion of the system are derived from the static structural problem in which dynamic inertia, gravitational and driving forces are treated as external loads. Linear spring model is included in the formulation of equation of motions to represent the effects of deformation of elastic bearings of revolute joints on the system behavior. A computer program is constructed and applied to analyze a specific crank-lever 4-bar mechanism. The algorithm of the program is as follows. First, the natural frequencies and the mode shapes of the system are calculated by solving the eigenproblem of the mechanism system which can be considered as a static structure by assuming the input shaft (crank shaft) to be fixed at any given configuration of mechanism. And finally, the elasto-dynamic deformation of the whole system is obtained using mode superposition method for the case of constant input speed. The effect of geometric stiffness on the mechamism is included in the program with the axial forces of links obtained through the quasi-static displacement analysis. It is found that the geometric stiffness exerts an important effect upon the elasto-dynamic behavior of the flexible linkage mechanism. Elastic deformation of bearing lowers the natural frequencies of the system, resulting smaller elastic displacement at the mid-point of the links and bigger elestic displacement at the ends of the links than rigid bearing. The above investigation of flexible linkage mechanism shows that the effects of the elastic deformation of bearing on the mechanism should be considered to design the mechanism which satisfies more preciously the purpose and the condition of design.

• Journal of Periodontal and Implant Science
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• v.46 no.6
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• pp.382-395
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• 2016

Purpose: Alendronate has been proposed as a local and systemic drug treatment used as an adjunct to scaling and root planing (SRP) for the treatment of periodontitis. However, its effectiveness has yet to be conclusively established. The purpose of the present meta-analysis was to assess the effectiveness of SRP with alendronate on periodontitis compared to SRP alone. Methods: Five electronic databases were used by 2 independent reviewers to identify relevant articles from the earliest records up to September 2016. Randomized controlled trials (RCTs) comparing SRP with alendronate to SRP with placebo in the treatment of periodontitis were included. The outcome measures were changes in bone defect fill, probing depth (PD), and clinical attachment level (CAL) from baseline to 6 months. A fixed-effect or random-effect model was used to pool the extracted data, as appropriate. Mean differences (MDs) with 95% confidence intervals (CIs) were calculated. Heterogeneity was assessed using the Cochrane ${\chi}^2$ and $I^2$ tests. Results: After the selection process, 8 articles were included in the meta-analysis. Compared with SRP alone, the adjunctive mean benefits of locally delivered alendronate were 38.25% for bone defect fill increase (95% CI=33.05%-43.45%; P<0.001; $I^2=94.0%$), 2.29 mm for PD reduction (95% CI=2.07-2.52 mm; P<0.001; $I^2=0.0%$) and 1.92 mm for CAL gain (95% CI=1.55-2.30 mm; P<0.001; $I^2=66.0%$). In addition, systemically administered alendronate with SRP significantly reduced PD by 0.36 mm (95% CI=0.18-0.55 mm; P<0.001; $I^2=0.0%$) and increased CAL by 0.39 mm (95% CI=0.11-0.68 mm; P=0.006; $I^2=6.0%$). Conclusions: The collective evidence regarding the adjunctive use of alendronate locally and systemically with SRP indicates that the combined treatment can improve the efficacy of non-surgical periodontal therapy on increasing CAL and bone defect fill and reducing PD. However, precautions must be exercised in interpreting these results, and multicenter studies evaluating this specific application should be carried out.

• Asian-Australasian Journal of Animal Sciences
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• v.23 no.6
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• pp.814-824
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• 2010

The objective of this research was to assess the effect of experience, education, record keeping, labor, and decision making on monthly milk yield per farm (MYF), monthly milk yield per cow (MYC), monthly milk revenue per farm (MRF), and monthly revenue per cow (MRC) of dairy farms supported by a private organization in Central Thailand. The dataset contained 34,082 monthly milk yield and revenue records collected from January 2004 to December 2008 on 497 farms, and information on individual farmer experience and education, record keeping, and decision making obtained with a questionnaire. Farmer experience categories were i) no experience, ii) one year, iii) two to five years, iv) six to ten years, v) eleven to fifteen years, vi) sixteen to twenty years, and vii) more than twenty years. Farmer education categories were i) no education or primary school, ii) high school, and iii) bachelor or higher degree. Record keeping categories were: i) no records and ii) kept records. Labor categories were: i) family, ii) hired people, and iii) family and hired people. Decision making categories were: i) decisions made by farmers themselves, ii) decisions made with help from government officials, and iii) decisions made with help from organization staff. The mixed linear model contained the fixed effects of year-season, farm location-farm size subclass, experience, education, record keeping, labor, and decision making on sire selection, and the random effects of farm and residual. Results showed that longer experience increased (p<0.05) monthly milk yield (MYF and MYC) and revenue (MRF and MRC). Farms that hired people produced the highest (p<0.05) monthly milk yield (MYF and MYC) and revenue (MRF and MRC), followed by farms that used family, and the lowest values were for farms that used both family and hired people. Better educated farmers produced more MYC and MRC (p<0.05) than lower educated farmers. Farms that kept records had higher MYF and MRF (p<0.05) than those without records. Although differences among farms were non-significant, farms that received help from the organization staff had higher monthly milk yield (MYF and MYC) and revenue (MRF and MRC) than those that decided by themselves or with help from government officials. These findings suggested that dairy farmers needed systematic training and continuous support to improve farm milk production and revenues in a sustainable manner.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.9
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• pp.69-76
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• 2018

The present study analyzed the effect of film hole position of 45 degree ribbed cooling channel on film cooling performance of gas turbine blades. We also investigated the influence of the ribs under the fixed blowing ratio. Three-dimensional numerical model was constructed and extensive simulation was conducted using the commercial code (Fluent ver. 17.0) under steady-state condition. Base on the simulation results, We investigated the cooling effectiveness, flow velocity, streamline, and pressure coefficient. Moreover, We analyzed the effect of cooling hole position on ejection of the secondary flow caused by the rib structure. From the results, It was found that internal flow of the cooling channel forms a vortex pair in the counterclockwise from the top side, and clockwise from the bottom side. For the channels with ribs, the vortex flow generated by the ribs caused a higher pressure difference near the hole outlet, resulting in at least 12% higher cooling effectiveness than the channel without ribs. Additionally, when the hole is located on the left side of the ribbed channel (Rib-Left), it can be found that the secondary flow generated by the ribs hits against wall surface near the hole to form a flow in the direction of the hole inclination angle. Therefore, It is considered that the region where the cooling gas discharged to the blade surface stays in the main flow boundary layer is wider than the other cases. In this case, The largest pressure coefficient difference was observed near the outlet of the hole, and as a result, the discharge of the cooling gas was accelerated and the cooling efficiency was slightly increased.

• Journal of Astronomy and Space Sciences
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• v.22 no.4
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• pp.441-450
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• 2005

The organic material is one of the most popular material for the satellites and the spacecrafts in order to perform the thermal management, and to protect direct exposure from the space environment. The present paper observes material property changes of organic material under the space environment by using ground facilities. One of the representative organic thermal management material of satellites, 2 mil ITO(Indium Tin Oxide) coated aluminized KAPTON was selected for experiments. In order to investigate the single parametric effect of protons in space environment, MC-50 cyclotron system in KIRAMS(Korea Institute of Radiological and Medical Science) was utilized for the ion beam irradiation of protons and ion beam dose was set to the Very Large August 1972 EVENT model, the highest protons occurrence near the earth orbit in history. The energy of ion beam is fixed to 30MeV(mesa electron volt), observed average energy, and the equivalent irradiance time conditions were set to 1-year, 3-year, 5-year and 10-year exposure in space. The procedure of analyses includes the measurement of the ultimate tensile strength for the assessment of quantitative degradation in material properties, and the imaging analyses of crystalline transformation and damages on the exposed surface by FE-SEM(Field Emission Scanning Electron Spectroscopy) etc.

• Journal of the Korean Society for Marine Environment & Energy
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• v.17 no.3
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• pp.182-188
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• 2014

In an oscillating water column (OWC)-type wave energy conversion system, the performance of the OWC chamber depends on the chamber shape, as well as the incident wave direction and pressure drop produced by the turbine. Although the previous studies on OWC chambers have focused on wave absorbing performance in ideal operating conditions, incident waves do not always arrive normally to the OWC chamber in real sea conditions, especially in fixed devices. The present study deals with experiments and numerical calculations to investigate the effects of wave direction on the performance of the OWC chamber. The experiments were carried out in a three-dimensional wave basin for five different wave directions, including the effect of turbine using the corresponding orifice. The wave elevation inside the chamber was measured at the center point under various incident wave conditions. The numerical study was conducted by using a numerical wave tank-based volume-of-fluid model to compare the results with experimental data and to reveal the detailed flows around the chamber.