• 제목/요약/키워드: Fixed-effect Model

Search Result 771, Processing Time 0.03 seconds

A Meta-analysis on the Association between Chronic Noise Exposure and Blood Pressure (만성적 소음노출과 혈압의 상관성에 관한 메타분석)

  • Kim, Chun-Bae;Kim, Jai-Young;Cha, Bong-Suk;Choi, Hong-Ryul;Lee, Jong-Tae;Nam, Chung-Mo;Lee, Sang-Yun;Wang, Seung-Jun;Park, Kee-Ho;Kim, Dae-Youl;Koh, Sang-Baek
    • Journal of Preventive Medicine and Public Health
    • /
    • v.33 no.3
    • /
    • pp.343-348
    • /
    • 2000
  • Objectives : This study was conducted to integrate the results of studies assessing the association between chronic noise exposure and blood pressure. Methods : Using a MEDLINE search with noise exposure, blood pressure and hypertension as key words, we retrieved articles from the literature that were published from 1980 to December 1999. The criteria for quality evaluation were as follows: 1) the study subjects must have been workers employed at a high noise level area 2) The paper should use average and cumulative noise exposure as method for exposure evaluation. 3) Blood pressure in each article should be reported in a continuous scale Among the 77 retrieved articles, six studies were selected for quantitative meta-analysis. Before the integration of the regression coefficients for the association between blood pressure and noise level, homogeneity tests were conducted. Results : All studies were a cross-sectional design and the study subjects were industrial workers. Five papers used a time-weighted average for noise exposure and only one paper calculated the cumulative noise exposure level. The measurement of blood pressure in the majority of studios were accomplished in a resting stale, and used an average of two or more readings. The homogeneity of studies was rejected in a fixed effect model, so we used the results in a random effect model. The results of the quantitative meta-analysis, the weighted regression coefficient of noise associated with systolic blood pressure and diastolic blood pressure were 0.05 (95% confidence interval [CI]: -0.03, 0.13) and 0.06 (95% CI: -0.01, 0.13), respectively. Conclusions : Our results suggested that chronic exposure to industrial noise does not cause elevated blood pressure.

  • PDF

A study on the effect of support structure of steel rib in partitioning excavation of tunnel (터널 상·하반 분할 굴착 시 강지보재 지지구조 효과에 대한 연구)

  • Kim, Ki-Hyun;Kim, Yeon-Deok;Hwang, Beoung-Hyeon;Choi, Yong-Kyu;Kim, Sang-Hwan
    • Journal of Korean Tunnelling and Underground Space Association
    • /
    • v.22 no.5
    • /
    • pp.543-561
    • /
    • 2020
  • This paper is the result of the study on the effect of the support structure of the tunnel steel rib. In tunnel excavation, the top and bottom half excavation methods result in subsidence of steel rib reinforcement due to insufficient support of steel rib reinforcement when the ground is poor after excavation. The foundation of the steel rib installed in the upper half excavates the bottom part of the base, causing the subsidence to occur due to various effects such as internal load and lateral pressure. As a result, the tunnel is difficult to maintain and its safety is problematic. To solve these problems, steel rib support structures have been developed. For the purpose of verification, the behavior of the supporting structure is verified by model experiments reduced to shotcrete and steel rib material similarity, the numerical analysis of ΔP and ΔP generated by bottom excavation by Terzaghi theoretical equation. As a result, it was found that the support structure of 20.100~198.423 kN is required for the 10~40 m section of the depth for each soil of weathered soil~soft rock. In addition, as a result of the reduced model experiment, a fixed level of 50% steel rib deposit of steel rib support structure was installed. The study shows that the installation of steel rib support structures will compensate for uncertainties and various problems during construction. It is also thought that the installation of steel rib support structure will have many effects such as stability, economy, and air reduction.

A sectoral comparison of the influence of the intellectual property rights system on technological innovation and financial performance: Korean pharmaceutical, semiconductor and shipbuilding industries (지식재산권 강화가 기술혁신과 경영성과에 미치는 영향의 산업별 비교연구: 한국의 제약, 반도체, 조선 산업)

  • Cho, Kyung-Chul;Kim, Chang-Seok;Shin, June-Seuk
    • Journal of Technology Innovation
    • /
    • v.21 no.2
    • /
    • pp.169-197
    • /
    • 2013
  • Despite many theoretical and empirical studies, general causality between IPRs system, firm technological innovation and financial performance is not clear. This study notices that the core factor to create financial performance is different by each industry. The study analyzed the effect of IPRs system on innovation and economic growth targeting 3 industries; pharmaceutical industry to which the basic track of creating performance is applied (strengthening IPRs${\rightarrow}$increasing R&D input/output${\rightarrow}$increasing sales); semiconductor industry where the relationship between stronger IPRs and R&D input/output is weak; and shipbuilding industry which has weak correlation between R&D and sales. It used panel data for 15 years since TRIPs when the patent institution in Korea reached up to the level of advanced countries, and applied the dynamic regression model which estimates the fixed effect model with difference-GMM. As a result, stronger IPRs increased R&D input/output, and financial performance in pharmaceutical industry, but has no influence on semiconductor and shipbuilding industries. That is, it is necessary to customize the construction of system and policy for strengthening IPRs by each industry, and unitary strengthening or weakening may have no significant impact on financial performance improvement in specific sectors.

  • PDF

An Analysis of the Determinants of Foreign Direct Investment in the Western China, 1990-2007 (중국 서부지역 외국인직접투자(FDI)의 결정요인에 관한 분석: 1990-2007 기간을 중심으로)

  • Peng, Xian-Feng;Choi, Sung-Il
    • International Area Studies Review
    • /
    • v.15 no.3
    • /
    • pp.471-491
    • /
    • 2011
  • This study is to analyze the determinants of inflow FDI with panel data of 12 provinces in western region of China for the period, 1990-2007, from the perspective of market-oriented FDI and production-efficiency-oriented FDI. The empirical findings are following. First, the empirical results prior to the start of western development program show that the GRDP, the intense of industrialization and university graduates per 10,000 residents have positive coefficient signs at the significant level, while wage level has a negative and significant value. Second the empirical results using the data after the launching of the western development program show that the GRDP, the intense of industrialization have positive relations with FDI, while openness in terms of the ratio of international trade to GRDP and the wage level have negative coefficients. Finally, this thesis finds that the empirical results for both periods are very similar, which suggest that the economic structure in western region has not changed significantly even though almost a decade passed since the western development program launched.

Genetic Relationship of Productive Life, Production and Type Traits of Korean Holsteins at Early Lactations

  • Wasana, Nidarshani;Cho, GwangHyun;Park, SuBong;Kim, SiDong;Choi, JaeGwan;Park, ByungHo;Park, ChanHyuk;Do, ChangHee
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.28 no.9
    • /
    • pp.1259-1265
    • /
    • 2015
  • The present study was performed to study the genetic relationship of productive life with production and type traits of Korean Holsteins at first three lactations. The data for the analysis from 56,054, 28,997, and 11,816 animals of first, second and third parity cows which were born from 2006 to 2011 were collected by Dairy Cattle Improvement Center, National Agricultural Co-operative Federation. Milk, protein and fat yields adjusted for 305 days and average somatic cell score considered as production traits and analyzed type traits were stature, strength, body depth, dairy form, rump angle, rump width, rear leg side view, foot angle, front attachment placement, rear attachment height, rear attachment width, udder cleft, udder depth, front teat placement and front teat length. A multi trait genetic analysis was performed using Wombat program with restricted maximum likelihood animal model composed of fixed effect of birth year, farm and the random effect of animal and random residual effect according to the traits. Heritability estimates of productive life were between 0.06 and 0.13. Genetic and phenotypic correlations between production and productive life traits ranged from 0.35 to 0.04 for milk, 0.16 to 0.05 for protein and 0.18 to 0.02 f 15-0034 (2nd) 150520 or fat. Somatic cells score showed a negative genetic and phenotypic correlation with productive life and also udder type traits, indicating that the selection for higher udder traits will likely to improve resistance to mastitis and persistence in the herd. Among all dairy form type traits, udder characters such as udder cleft showed a significant relationship with productive life. However, a specific change of heritabilities or correlations were not observed with the change of parity. Moreover, further studies are needed to further confirm the significance of the above traits and the effect of parity on above relationships in order to minimize both voluntary and involuntary culling rates while improving herd health and maintaining high yielding dairy cows.

Luteinizing hormone beta gene polymorphism and its effect on semen quality traits and luteinizing hormone concentrations in Murrah buffalo bulls

  • Reen, Jagish Kour;Kerekoppa, Ramesha;Deginal, Revanasiddu;Ahirwar, Maneesh Kumar;Kannegundla, Uday;Chandra, Satish;Palat, Divya;Das, Dayal Nitai;Kataktalware, Mukund Amritrao;Jeyakumar, Sakthivel;Isloor, Shri krishna
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.31 no.8
    • /
    • pp.1119-1126
    • /
    • 2018
  • Objective: Present investigation was aimed to study the Single Nucleotide Variants of the luteinizing hormone beta ($LH{\beta}$) gene and to analyze their association with the semen quality (fresh and post-thawed frozen semen) and luteinizing hormone (LH) concentrations in Murrah buffalo bulls. Methods: Polymerase chain reaction-single stranded conformational polymorphism (PCR-SSCP) and Sanger sequencing method is used to study genetic variability in $LH{\beta}$ gene. LH assay was carried out using enzyme-linked immunosorbent assay method. A fixed general linear model was used to analyze association of single nucleotide polymorphism (SNP) of $LH{\beta}$ gene with semen quality in 109 and LH concentrations in 80 Murrah bulls. Results: $LH{\beta}$ gene was found to be polymorphic. Total six SNPs were identified in $LH{\beta}$ gene g C356090A, g C356113T, g A356701G, g G355869A, g G356330C, and g G356606T. Single Stranded Conformational Polymorphism variants of pattern 2 of exon 1+pattern 2 of exon 2+pattern 1 of exon 3 had highly significant (p<0.01) effect on sperm concentration (million/mL), percent mass motility, acrosome integrity and membrane integrity in fresh and frozen semen whereas significant (p<0.05) effect was observed on percent live spermatozoa. SSCP variants of pattern 2 of exon 1+pattern 2 of exon 2+pattern 1 of exon 3 had highly significant (p<0.01) effect on luteinizing hormone concentrations too. Conclusion: The observed association between SSCP variants of $LH{\beta}$ gene with semen quality parameters and LH concentrations indicated the possibilities of using $LH{\beta}$ as a candidate gene for identification of markers for semen quality traits and LH concentrations in Murrah buffaloes.

Effect of the Number and Location of Implants on the Stress Distribution in Three-unit Fixed Partial Denture: A Three-Dimensional Finite Element Analysis (임플란트 고정성 보철물에서 수와 식립위치 변화에 따른 골과 임플란트에서의 응력분포에 관한 3차원 유한요소법적 연구)

  • Lee, Woo-Hyun;Lim, Jong-Hwa;Cho, In-Ho
    • Journal of Dental Rehabilitation and Applied Science
    • /
    • v.26 no.3
    • /
    • pp.221-239
    • /
    • 2010
  • Bone loss may occur depending on the loading conditions. careful treatment planning and prosthetic procedures are very important factors for the proper distribution of stress. Evaluate the stress distributions according to numbers and location of implants in three-unit fixed partial dentures. A mandible missing the right second premolar, first molar and second molar was modeled. Using the CT data. we modeled a mandible with a width of 15mm, a height of 20mm and a length of 30mm, 2mm-thickness cortical bone covering cancellous bone mallow. An internal type implant and A solid type abutment was used. A model with 3 implants placed in a straight line, offset 1.5 mm buccally, offset 1.5 mm lingually and another model with 3 implants offset in the opposite way were prepared. And models with 2 implants were both end support models, a mesial cantilever model and a distal cantilever model. Three types of loading was applied; a case where 155 N was applied solely on the second premolar, a case where 206 N was applied solely on the second molar and a case where 155 N was applied on the first premolar and 206 N was applied on the first and second molar. For all the cases, inclined loads of 30 degrees were applied on the buccal cusps and vertical loads were applied on the central fossas of the teeth. Finite element analysis was carried out for each case to find out the stress distribution on bones and implants. This study has shown that prostheses with more implants caused lower stress on bones and implants, no matter what kind of load was applied. Furthermore, it was found out that inclined loads applied on implants had worse effects than vertical loads. Therefore, it is believed that these results should be considered when placing implants in the future.

Throughput Performance of Slotted ALOHA Communication System with Guard Time and Capture Effect (신호점유 현상과 보호시간을 고려한 슬롯형 알로아 통신 시스템의 성능분석)

  • 이현구;곽경섭
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.18 no.7
    • /
    • pp.989-998
    • /
    • 1993
  • In a bursty user traffic mode, ALOHA random multiple access protocol achieves higher performance than any conventional fixed assignment technique. One of central problems in slotted ALOHA is synchronization. Because of the long propagation delay in satellite mobile communication, packet may be spilt over into adjacent slots and thus guard time may be included between packet intervals. In conventional ALOHA channels, simultaneous transmission by two or more users results in a collision : the unsuccessful packets have to be retransmitted according to some retransmission algorithm. However, in a radio environment, users are often at different distances from the receiver : therefore, their received signals have substantially different power levels. The packet arriving with the highest energy now has a good chance of being detected accurately. Similarly, in some spread-spectrum random access systems, the earliest arriving packet dominates later arriving packets and thus captures the channel. In this paper slotted ALOHA channel with non zero guard time and capture probability is studied. Using the Markovian model, the performance of slotted ALOHA with guard time and capture effects is derived and compared with that of the conventional ALOHA via numerical analysis.

  • PDF

A Study on Longitudinal Flight Dynamics of a QTW UAV (QTW 무인항공기의 종축 비행동역학에 관한 연구)

  • Jung, Ji In;Hong, Sung Tae;Kim, Seungkeun;Suk, Jinyoung
    • Journal of the Korean Society for Aeronautical & Space Sciences
    • /
    • v.41 no.1
    • /
    • pp.31-39
    • /
    • 2013
  • A Quad Tilt Wing UAV is a new concept hybrid UAV having the advantages of both fixed-wing and rotary-wing aircraft. This paper presents longitudinal flight dynamic characteristics of a Quad Tilt Wing UAV. The designed Quad Tilt Wing UAV is a configuration of a tandem wing type aircraft with an actuating motor and propeller mounted at each wing. Momentum theory is used to calculate the thrust, and nonlinear modeling is performed considering lift and drag generated by slip stream effect of propellers. Also, Force and moment variation at each tilting angle is considered. Static trim on longitudinal axis is analyzed via numerical simulation. Componentwise force contribution was analyzed at each trim mode. Dynamic characteristics were evaluated through eigenvalue analysis for a linear model at each flight mode. It is verified that longitudinal dynamic characteristics are changing from unstable to stable state by continuous transition of dominant poles.

Parametric Sensitivity Analyses of Linear System relative to the Characteristic Ratios of Coefficient (I) : A General Case (계수의 특성비에 대한 선형계의 파라미터적 감도해석(I): 일반적인 경우)

  • 김영철;김근식
    • Journal of Institute of Control, Robotics and Systems
    • /
    • v.10 no.3
    • /
    • pp.205-215
    • /
    • 2004
  • The characteristic ratio assignment (CRA) method〔1〕 is new polynomial approach which allows to directly address the transient responses such as overshoot and speed of response time in time domain specifications. The method is based on the relationships between time response and characteristic ratios($\alpha_i$ ) and generalized time constant (T), which are defined in terms of coefficients of characteristic polynomial. However, even though the CRA can apply to developing a linear controller that meets good transient responses, there are still some fundamental questions to be explored. For the purpose of this, we have analyzed several sensitivities of a linear system with respect to the changes of coefficients itself and $\alpha_i$ of denominator polynomial. They are (i) the unnormalized root sensitivity : to determine how the poles change as $\alpha_i$ changes, and (ii) the function sensitivity to determine the sensitivity of step response to the change of o, and to analyze the sensitivity of frequency response as o, changes. As an other important result, it is shown that, under any fixed T and coefficient of the lowest order of s in denominator, the step response is dominantly affected merely by $\alpha_1, alpha_2 and alpha_3$ regardless of the order of denominator higher than 4. This means that the rest of the$\alpha_i$ s have little effect on the step response. These results provide some useful insight and background theory when we select $\alpha_i$ and T to compose a reference model, and in particular when we design a low order controllers such as PID controller.