• Asian-Australasian Journal of Animal Sciences
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• 제12권1호
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• pp.22-27
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• 1999

Bovine oocytes with compact and complete cumulus cells were cultured in 6 groups for up to 24h in TCM199 buffered with 25 mmol/1 HEPES and supplemented with 10% FCS, 1 mg/ml $17{\beta}$-estradiol, 20 IU/ml hCG. Half of the oocytes at each group cultured in the presence of $25{\mu}g/ml$ cycloheximide at different times during maturation (0, 6, 12, 18, 20, 22 h) were fixed at 24 h of maturation to examine the nuclear progression. The rests of them were inseminated with frozen-thawed spermatozoa in medium BO with 10 mg/ml BSA and 10 mg/ml heparin and fixed after additional 18-20 h culture to evaluate the sperm head transformation. When a protein synthesis inhibitor was added at the onset of the maturation, the oocytes were prevented to proceed GVBD. A few of the oocytes (16%) were able to be penetrated and sperm head decondensation was inhibited either. Addition of cycloheximide after 6-12 h of culture resulted in an increasing percentage of GVBCD (more than 80%), but the oocytes became arrested in M-I (69.2%). More than half of the oocytes was penetrated with a decondensing sperm head. Formation of male pronucleus was first obtained at 12 h of culture in the presence of cycloheximide. When cycloheximide was added from 18 h of culture onwards, nuclear progression to M-II was increasingly restored (80.4-85.5%). The proportion of male and female pronuclear formation increased from 17.9% to 46.2%. It is concluded that protein synthesis is necessary not only for GVBD and development from M-I to M-II, but also for sperm head decendensation and male pronuclear formation in bovine oocytes.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.144-145
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• 2002

Stereotactic radiotherapy is required to irradiate a small tumor accurately. The radiotherapy showing improves when making an accidental error little boundlessly. It is performed according to treatment planning that is established by the outside landmark of head. At present, when stereotactic radiotherapy for a head is done, the Leksell Flame is fixed on the head, and positioning based on the point and so on which it is in that fixed implement is performed. However, there are problems on the method done at present in the point such as reappearance when the fractionated irradiation method in which the Leksell Flame is removed and installed at every treatment is done because there are landmarks outside the head. Landmarks in the skull were decided, and that precision was examined for the purpose of the improvement of the radiation therapeutic gain. Linac-graphy with longitudinal and lateral view were taken with 6 MV photon beams. A distance to base point inside the skull, each film measured the angle from a center of the small irradiation field, and comparison was done. From the results, a large accidental error wasn't seen as a result of the measurement by every film. Stereotactic radiotherapy for a head treatment had an accidental error of about several millimeters when treatment positioning was done. Therefore, it was thought that there was no problem about an accidental error to arise by putting a landmark in the skull. And, because an accidental error was easy to discover, we thought that modification could be done easily. It was suggested that a landmark in the skull on thus study were useful for improvement of stereotactic radiotherapy.

• 대한인간공학회지
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• 제16권3호
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• pp.1-10
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• 1997

This paper is concerned with the development and evaluation of the camera calibration method for a real-time head tracking system. Tracking of head movements is important in the design of an eye-controlled human/computer interface and the area of virtual environment. We proposed a video-based head tracking system. A camera was mounted on the subject's head and it took the front view containing eight 3-dimensional reference points(passive retr0-reflecting markers) fixed at the known position(computer monitor). The reference points were captured by image processing board. These points were used to calculate the position (3-dimensional) and orientation of the camera. A suitable camera calibration method for providing accurate extrinsic camera parameters was proposed. The method has three steps. In the first step, the image center was calibrated using the method of varying focal length. In the second step, the focal length and the scale factor were calibrated from the Direct Linear Transformation (DLT) matrix obtained from the known position and orientation of the camera. In the third step, the position and orientation of the camera was calculated from the DLT matrix, using the calibrated intrinsic camera parameters. Experimental results showed that the average error of camera positions (3- dimensional) is about $0.53^{\circ}C$, the angular errors of camera orientations are less than $0.55^{\circ}C$and the data aquisition rate is about 10Hz. The results of this study can be applied to the tracking of head movements related to the eye-controlled human/computer interface and the virtual environment.

• Journal of Korean Neurosurgical Society
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• 제45권5호
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• pp.306-308
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• 2009

The Mayfield head clamp is the most frequently used head clamp system in the field of neurosurgery. In many cases, surgery is performed with complete reliance on the safety of the MHC. However, we experienced an extremely rare case in which the MHC accidentally broke while installing this system for immobilization of the head and neck. This is a case report with a brief review of the literature. The patient was a 58-year-old female who was scheduled to undergo cervical laminoplasty under the diagnosis of degenerative spondylotic cervical stenosis. In an attempt to install an MHC, we fixed three pins in the scalp; however, the arm of the MHC system broke when force was applied from both directions. Fortunately, the patient remained in a stable position and did not sustain an injury to the head or neck. Fixation was performed using another MHC, and the surgery was performed successfully. The patient was discharged after surgery with no specific complications related to the MHC system. The authors experienced an extremely rare case of MHC breakage during application and report the importance of properly managing and maintaining the instruments in order to prevent fatal injury.

• 대한두경부종양학회지
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• 제33권1호
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• pp.39-41
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• 2017

Salivary gland tumors comprise almost 5% of head and neck malignancies, and minor salivary gland tumor which account for 10-15% of all salivary gland neoplasm are infrequently malignant. The mucoepidermoid carcinoma (MEC) is second most common tumor in minor salivary gland. It usually presents as a painless, rubbery-hard or soft mass, which may be fixed or mobile into the underlying structure. The predilection sites of intraoral MEC are palate, cheek, mandible, lip, and tongue, etc. There are very few published reports of MEC occurred in retromolar trigone. Only one case has been reported so far. Recently, we experienced a-70-year old man with a mass in retromolar trigone, which was finally diagnosed as MEC. We report the unique case with literature review.

• 신재생에너지
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• 제20권1호
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• pp.116-125
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• 2024

Ultra-low-head is an unexplored classification among the sites in which hydroelectric power can be produced. This is typically owing to the low power output and the economic value of the turbines available in this segment. A turbine capable of operating in an ultra-low-head condition without the need of a dam to produce electricity is developed in this study. A gate structure installed at a shallow water channel acting as a weir generates artificial head for the turbine mounted on the gate to produce power. The turbine and generator are designed to be compact and submersible for an efficient and silent operation. The gate angle is adjustable to operate the turbine at varying flow rates. The turbine is designed and tested using computational fluid dynamics tools prior to manufacturing and experimental studies. A parametric study of the runner blade parameters is conducted to obtain the most efficient blade design with minimal hydraulic losses. These parameters include the runner stagger and runner leading edge flow angles. The selected runner design showed improved hydraulic characteristics of the turbine to operate in an ultra-low-head site with minimal losses.

• 한국초전도ㆍ저온공학회논문지
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• 제14권4호
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• pp.50-53
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• 2012

This paper describes experimental study on GM-type pulse tube refrigerator (PTR). In a PTR, the pulse tube is only filled with working gas and there exists secondary flow due to a large temperature difference between cold-end and warm-end. The stability of secondary flow is affected by orientation of cold-head and thus, the cooling performance is deteriorated by gas mixing due to secondary flow. In this study, a single stage GM-type pulse tube refrigerator is fabricated and tested. The cooing performance of the fabricated PTR is measured as varying cold-head orientation angle and the results are used as reference data. Then, we divided interior space of pulse tube into three segments, and fixed the various size of screen mesh at interface of each segment to suppress the performance degradation due to secondary flow. For various configuration of pulse tube, no-load test and heat load test are carried out with the fixed experimental condition of charging pressure, operating frequency and orifice valve turns. From experimental results, the fine screen mesh shows the effective suppression of performance degradation for the large orientation angle, but the use of screen mesh cause the loss of cooling capacity rather than the case of no insertion into pulse tube. It should be compromised whether the use of screen mesh in consideration of the installation limitation of a GM-type pulse tube refrigerator.

• International Journal of Fluid Machinery and Systems
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• 제2권4호
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• pp.392-399
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• 2009

The paper concerns the description of the step by step development process of the new fixed blade runner called "Mixer" suitable for the uprating of the Francis turbines units installed at the older low head hydropower plants. In the paper the details of hydraulic and mechanical design are presented. Since the rotational speed of the new runner is significantly higher then the rotational speed of the original Francis one, the direct coupling of the turbine to the generator can be applied. The maximum efficiency at prescribed operational point was reached by the geometry optimization of two most important components. In the first step the optimization of the draft tube geometry was carried out. The condition for the draft tube geometry optimization was to design the new geometry of the draft tube within the original bad draft tube shape without any extensive civil works. The runner blade geometry optimization was carried out on the runner coupled with the draft tube domain. The blade geometry of the runner was optimized using automatic direct search optimization procedure. The method used for the objective function minimum search is a kind of the Nelder-Mead simplex method. The objective function concerns efficiency, required net head and cavitation features. After successful hydraulic design the modal and stress analysis was carried out on the prototype scale runner. The static pressure distribution from flow simulation was used as a load condition. The modal analysis in air and in water was carried out and the results were compared. The final runner was manufactured in model scale and it is going to be tested in hydraulic laboratory. Since the turbine with the fixed blade runner does not allow double regulation like in case of full Kaplan turbine, it can be profitably used mainly at power plants with smaller changes of operational conditions or in case with more units installed. The advantages are simple manufacturing, installation and therefore lower expenses and short delivery time for turbine uprating.

• 대한두경부종양학회지
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• 제16권1호
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• pp.3-8
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• 2000

Background and Objectives: Adenoid cystic carcinoma of salivary glands is characterized by insidious growth over many years, local recurrences, and distant metastasis and classified to three distinct histologic subtypes: tubular, cribriform, and solid. The solid type is known to have the worst prognosis. However, histopathologic heterogeneity is observed in tumors from the same patient. We have attempted to elucidate the genotypic differences, characterized by polysomies of chromosome 17, in adenoid cystic carcinoma according to the phenotypic histopathologic heterogeneity. Materials and Methods: Fluorescence in situ hybridization was performed on formalin-fixed paraffin blocks from seven patients with head and neck adenoid cystic carcinoma, using the centromeric $\alpha$-satellite probe of chromosome 17 to detect nuclei exhibiting polysomy. The difference in polysomeric chromosome expression in cribriform, tubular, solid type and type I, II, III according to the Szanto classification was analyzed. Results: Polysomy of chromosome 17 was found in 15.28% of the cribriform type, in 15.68% of the tubular type, and in 18.87% of the solid type. The proportion of polysomy was statistically higher in the solid type than in the cribriform type(p<0.05), and the proportion of polysomy increased progressively from type 1 to type 3, but this trend was statistically insignificant(p>0.05). Conclusion: We suggest that there may be genetic variations in tumor from the same patient depending on the histopathologic heterogenetiy in adenoid cystic carcinomas.

• 한국자동차공학회논문집
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• 제19권2호
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• pp.92-97
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• 2011

Vehicle lightings are very important for safe driving during night time. Since the eye recovery time after an exposure to oncoming headlights would take after several seconds, the aiming point of vehicle head lamps have to pass safety requirements. Despite the fact that vehicle inclination is variable with vehicle load conditions, the head lamps aiming point is usually fixed at a constant position which is set by car manufacturer. Consequently, vehicle head lamps under varying load conditions often make people in the opposing vehicle uncomfortable, and even worse, can cause an accident. This paper presents an active vehicle lighting mechanism to automatically adjust its aiming point, or cut-off line, in order to compensate the change in vehicle inclination resulting from load variations. The effectiveness of the proposed method is demonstrated through a set of simulations and experiments with a real vehicle.