• Title/Summary/Keyword: Fish Drug

검색결과 178건 처리시간 0.025초

어류 약물정보시스템의 구현 및 응용 (Implementation and Application of Fish Drug Information System)

  • 김해란;박계화;조혁현;정희택
    • 한국전자통신학회논문지
    • /
    • 제2권2호
    • /
    • pp.92-98
    • /
    • 2007
  • 수산용 의약품의 목록을 데이터베이스 화 한 어류약물정보시스템엔 상품명, 대상어종, 유효성분, 제조회사명, 적응증(질병) 등 약물에 대한 다양한 자료와 제조회사정보, 식품의 기준 및 규격에 관한 자료가 들어있다. 또한 추후에는 어류 질병에 대한 상세 자료를 데이터베이스 화 한 어류질병정보시스템을 구축할 것이다. 따라서 약물정보시스템과 질병정보시스템을 근간으로 한 어류질병판별시스템에서 질병 판정 후 치료에 필요한 처방전 발행과 약품 주문 등에 응용 활용할 것을 제안한다.

  • PDF

시맨틱 웹기반 수산용 의약품 정보시스템 설계 (A Design of semantic web-based fish drug information system)

  • 정희택;김해란;한순희
    • 한국정보통신학회논문지
    • /
    • 제14권1호
    • /
    • pp.145-155
    • /
    • 2010
  • 본 연구는 키워드 기반의 단순 검색이 아닌 개념의 관계와 추론을 통해 연관정보 및 계층 정보를 함께 보여 줄 수 있는 수산용의약품 도메인 온톨로지 구축 방안을 제안한다. 이를 위해 수산분야 종사자들로부터 적합성질문 목록을 조사하여 개념 및 용어를 도출하는 선행과정을 수행한다. 다음으로 온톨로지 언어인 OWL을 지원하는 Protege-OWL 편집기를 이용하여 온톨로지 모델링 과정을 기술한다. 그리고 마지막으로 구축된 온톨로지를 통해 사용자들이 수산용의약품에 대한 관련 정보를 쉽게 찾아갈 수 있는 사용자 인터페이스를 제안한다. 이는 수산용의약품과 연관된 질병, 어종, 약품평가 내역을 다른 위치로 이동하지 않고 한 화면 내에서 확인 할 수 있게 됨으로써 관련 전공학생, 수산질병관리사, 양식어민들에게 필요한 정보에 대한 효과적인 검색 방법을 제공한다.

Mercury and Methylmercury Levels in Marine Fish Species from Korean Retail Markets

  • Oh, Keum-Soon;Suh, Jung-Hyuck;Park, Seong-Soo;Paek, Ock-Jin;Yoon, Hae-Jung;Kim, Hee-Yeon;Lee, Jong-Ok
    • Food Science and Biotechnology
    • /
    • 제17권4호
    • /
    • pp.819-823
    • /
    • 2008
  • Mercury and methylmercury concentrations were measured in 225 marine fish samples purchased from retail markets in 5 major Korean cities in 2005. The results showed that the concentrations of mercury and methylmercury ranged from 0.006-0.455 (mean=$0.054{\pm}0.025$) mg/kg and 0.004-0.120 (mean=$0.021{\pm}0.008$) mg/kg, respectively, in fish caught from the coastal waters of the Korean Peninsula. The concentrations in deep-sea fish including tuna ranged from 0.066-2.315 (mean=$0.095{\pm}0.640$) mg/kg for mercury and 0.027-0.897 (mean=$0.281{\pm}0.182$) mg/kg for methylmercury. The estimated weekly intakes (EWIs) of mercury and methylmercury reached 3.92 and 4.70% of the provisional tolerable weekly intakes (PTWI), respectively. Consequently, the levels of mercury and methylmercury in marine fish from current retail markets do not pose any significant health risks for Koreans.

수입산 담수관상어 및 양식 해산어의 장내세균에서 나타나는 내성균 위험성 비교 (Comparative risks of resistant microorganisms in the intestinal track of imported freshwater ornamental fish and cultured marine fish)

  • 윤소혜;전려진;김영진;진지웅;정현도
    • 한국어병학회지
    • /
    • 제25권2호
    • /
    • pp.77-84
    • /
    • 2012
  • Various antibiotics, that could induce the appearance of resistant microorganisms, have been used for treatment or prevention of bacterial diseases in marine and ornamental fish. We determined and characterized the level of antibiotic-resistant bacteria and proportion of multi-drug resistant bacteria in intestinal microflora of both marine fish cultured in Korea and imported ornamental freshwater fish. For this the bacterial species and resistance to antibiotics were investigated in intestine of rock bream Oplegnathus fasciatus cultured in Korea and pearl gourami Trichogaster leeri imported from Singapore to characterise. Although the bacterial species were different, proportions of resistant bacteria to single antibiotics or multi-drug were higher in intestinal microflora of pearl gourami Trichogaster leeri imported from Singapore than in rock bream Oplegnathus fasciatus cultured in Korea. These results indicate that various antibiotics have been being used before trading without measures in the market of asian ornamental fishes, providing high risks for the emergence of multi-drug resistant bacteria.

천연산 및 양식산 뱀장어, 복어, 가물치의 맛 성분에 대한 연구 (Comparison of The Taste Compounds of Wild and Cultured Eel, Puffer and Snake head)

  • 김희연;신재욱;심규창;박희옥;김현숙;김상무;조재선;장영미
    • 한국식품과학회지
    • /
    • 제32권5호
    • /
    • pp.1058-1067
    • /
    • 2000
  • In this study, eel, puffer and snake head fish, which are widely taken and highly valued for processing into baked fish, soup or fish juice were studied by classifying them into wild fish and cultured fish, and evaluated in terms of taste. The samples were gathered in the area including Kimhae, Samchonpo and Haman in Kyungsangnam-do, Kangsu-Gu in Pusan and Bukcheju-Gun in Cheju-do. Proximate compositions, the content of nucleotides and their related compounds, total and free amino acids, organic acids and fatty acids of the fishes were analysed. Generally, as for the compositions, wild fish had a higher crude fat content and a lower moisture content as compared with cultured fish, while there was no great difference between them in terms of crude protein and ash contents. Nucleotides and their related compounds including ATP, ADP, AMP, IMP, HxR, Hx were detected, and the amounts of which were nearly the same with respect to the growth conditions. IMP content was high in all of the samples, while ATP content was extremely low. Total 17 amino acids were detected from the samples, and most of the samples had high contents of glutamic acid, aspartic acid, lysine, leucine, glycine, alanine and arginine, and low contents of cystein, isoleucine and methionine. As for the other amino acids, generally same level of contents were detected for each samples. In cases of eel and snake head fish, the wild fish had higher total amino acid contents in comparison with cultured fish. And the result to the contrary was obtained for the case of puffer. Sample fishes had nearly the same compose distribution of free amino acid though the contents of which were a little different according to the samples. Each sample had high contents of taurine, hydroxyproline, glutamic acid, glycine, cystathionine, ${\beta}-aminoisobutyric$ acid and lysine. Total organic acid contents of cultured fish was higher than that of wild fish. All fishes commonly had high contents of lactic acid, iso-valeric acid, oxalic acid and fumaric acid. High levels of $C_{16:0},\;C_{16:1},\;C_{18:1(cis)},\;C_{18:3},\;and\;C_{22:6}$ were shown in all of the samples and ${\omega}-3$ polyunsaturated fatty acid content of cultured fish was higher than that of wild fish, and as for the essential fatty acid, wild fish has higher content in comparison with cultured fish.

  • PDF

일반 프라이머를 이용한 PCR의 식품원료 진위 판별에 적용 (Application for Identification of Food Raw Materials by PCR using Universal Primer)

  • 박용춘;진상욱;임지영;김규헌;이재황;조태용;이화정;한상배;이상재;이광호;윤혜성
    • 한국식품위생안전성학회지
    • /
    • 제27권3호
    • /
    • pp.317-324
    • /
    • 2012
  • 본 연구는 식품원료의 진위여부를 판별하기 위한 시험법으로 일반 프라이머를 이용한 DNA barcode 기법을 도입하였다. 동물성식품원료의 경우 미토콘드리아 DNA 중 cytochrome oxidase subunit I(COI) 부위 검출을 위하여 디자인된 프라이머(LCO1490/HCO2198 및 VF2/FISH R2)와 cytochrome b(cyt b) 부위 검출을 위하여 디자인된 프라이머(L14724/H15915)를 사용하였다. 상기 3 종류의 프라이머를 사용하여 가축류 6종(소, 돼지, 염소, 양, 말 및 사슴), 가금류 4종(닭, 오리, 칠면조 및 타조), 어류 7종(명태, 대구, 청대구, 청어, 송어, 다랑어 및 우럭)을 대상으로 PCR 후 전기영동하여 예상되는 PCR 산물의 생성 유무를 확인하였다. 가축류 6종에 대하여는 LCO1490/HCO2198, VF2/FISH R2 및 L14724/H15915 프라이머를 사용한 경우 COI 및 cyt b가 모두 검출되었으며, 가금류 4종은 LCO1490/HCO2198 및 VF2/FISH R2 프라이머를 사용한 경우만 COI이 검출되었다. 또한 어류 7종은 VF2/FISH R2 프라이머를 사용한 경우에만 COI 부위가 검출됨을 확인하였다. 식물의 경우 엽록체 DNA 부위를 이용하여 디자인된 3 종류의 프라이머(trnH/psbA, rpoB 1F/4R 및 rbcL 1F/724R)를 사용하였다. 각각의 프라이머를 이용하여 식물 5종(마늘, 양파, 무, 녹차 및 시금치)에 대하여 실험한 결과 3종류의 프라이머에서 PCR의 산물을 모두 확인하였으며 trnH/psbA 프라이머의 경우 식물 종마다 PCR 산물의 크기는 다르게 검출되었다. 본 연구에서는 17종의 식품원료별 일반 프라이머 및 PCR 조건을 확립하였으며, 생산된 PCR 산물을 대상으로 염기서열을 결정하고 유전자은행에 있는 염기서열과 DB 비교 분석을 통하여 식품에 사용된 원료의 진위여부 판별에 적용이 가능할 것으로 기대된다.

서해안 수산생물에서 분리한 대장균(Escherichia coli)의 항생제 내성 및 다제 내성 양상 비교 (Comparison of Antimicrobial Resistance and Multi-Drug Resistance Patterns of Escherichia coli Isolated from Aquatic Organisms Off the West Coast of South Korea)

  • 정연겸;박보미;김민주;박진일;정연중;오은경
    • 한국수산과학회지
    • /
    • 제54권4호
    • /
    • pp.388-396
    • /
    • 2021
  • Antimicrobial resistance patterns of Escherichia coli were investigated. Strains were isolated from 310 shellfish, 36 crustaceans, and 12 fish collected off the West Coast of Korea from April 2019 to October 2020. Two hundred and ninety-five E. coli strains were isolated from shellfish, 100 from crustaceans, and 54 from fish. Strains isolated from shellfish showed the highest resistance to ampicillin (27.5%), whereas those from crustaceans were resistant to sulfisoxazole (30.0%) and those from fish were resistant to ampicillin (59.3%) and sulfisoxazole (59.3%). Ceftazidime resistance was observed in strains isolated from short neck and hard clams, whereas gentamicin resistance was observed in strains from fish. Multi-drug resistance was observed in 56 strains (48.7%) isolated from shellfish, 11 (28.2%) from crustaceans and 27 (73.0%) from fish. Depending on the source of isolation, the strains showed specific antimicrobial resistance tendency. Strains isolated from shellfish showed 12 different multi-drug resistance patterns, whereas those from crustaceans showed high resistance (59%) to a single antimicrobial agent and those from fish showed a broad trend of multi-drug resistance to more than eight antimicrobials.

축산물과 수산물에서 분리된 장구균의 항생제 감수성 및 유전형 분석 (Monitoring of Antimicrobial Resistance and Genetic Analysis of Enterococcus spp. Isolated from Beef, Pork, Chicken and Fish in Korea)

  • 김윤정;오미현;김용훈;김순한;박건상;주인선
    • 한국식품위생안전성학회지
    • /
    • 제29권3호
    • /
    • pp.228-233
    • /
    • 2014
  • This study was performed to examine antimicrobial resistance of Enterococcus spp. strains from retail raw meat and fish products purchased in 2012. 43 Enterococcus spp. strains were isolated from a total of 207 samples (beef, pork, chicken, fish) with contamination rate of 20.8%. The isolated strains were identified as E. faecalis (22 strains), E. gallinarum, E. hirae (5 strains), E. avium (4 strains), E. faecium (3 strains), E. duram, E. casseliflavus (2 strains). Susceptibility to 10 antibiotics was tested, and the highest resistance was observed to tetracycline. And antimicrobial resistance rates were presented below 20% with most of the other antimicrobial agents. The isolated Enterococci from chicken showed higher resistance also to ciprofloxacin and erythromycin, not only to tetracycline, compared to the isolated Enterococci from beef, pork and fish. Sixteen isolates (37.2%) were sensitive to all antibiotics. Four isolates (9.3%) were resistant to 3 or more antibiotics. Vancomycin-resistant enterococci (VRE) was not identified. According to the results of genetic similarity pattern analysis via PFGE and rep-PCR, Enterococci strains showed different patterns from these collected in 2011. This indicates that there is no genetic similarity among all the strains.

LC-MS/MS를 이용한 수산물 중 콜리스틴 분석법 개발 (Development of Analytical Method for Colistin in Fish and Shrimp using Liquid Chromatography Mass Spectrometry)

  • 신다솜;강희승;이수빈;조윤제;천소영;정지윤;이규식
    • 한국식품위생안전성학회지
    • /
    • 제31권5호
    • /
    • pp.319-326
    • /
    • 2016
  • LC-MS/MS를 이용하여 폴리펩타이드계 동물용의약품인 콜리스틴에 대한 시험법을 확립하여 정량성 및 정밀성을 확보하였으며, 확립된 시험법의 적용성 검증을 위해 국제식품규격위원회 기준에 따라 특이성, 정확성, 직선성, 정밀성, 검출한계, 정량한계 등을 검증하였다. 콜리스틴 표준용액을 잔류허용기준의 농도에 따라 검량선을 작성한 결과 0.99 이상의 직선성을 확인 할 수 있었으며, 본 실험에서의 평균 회수율은 85.9~107%이었다. 또한, 분석오차는 11.8% 이하로 정확성 및 재현성이 우수하였으며, 검출한계는 0.02 mg/kg, 정량한계는 0.05 mg/kg이었다. 또한, 실험실간 교차검증을 통하여 신뢰성을 확보하였다. 확립된 분석법은 양식 수산물 중 잔류할 수 있는 동물용의약품인 콜리스틴에 대한 안전관리에 활용 할 수 있을 것으로 판단된다.

양식어류에 있어서 생약제제(바이오감마믹스)의 경구투여에 의한 효능 및 안전성에 관한 연구 (A study on efficacy and safety of Bio-Gammamix by oral administratiion to cultured fish)

  • 허강준;김병기;예제길;김정호
    • 대한수의학회지
    • /
    • 제34권3호
    • /
    • pp.627-633
    • /
    • 1994
  • A study on efficacy and safety of Bio-Gammamix was performed to use for the preventive drug against bacterial diseases to mirror carp(Cyprinus carpio), rainbow trout(Salmo gairdneri), eel(Anguilla japonica) and flounder(Paralichthys olivaceus). The main ingredients of Bio-Gammamix were ferrous fumarate and mixed extrated powders of licorice root, ox bile and garlic. The test drug was proved to improve feeding habit and feed efficiency and decrease cumulative mortality remarkably. After administration, no side effects and histopathological changes were observed. We can prevent outbreaks of bacterial diseases of fish by the dosage of 1kg/ton of fish body weight perorally once or two times in a day for 7 days and Bio-Gammamix is thought to be used effectively an widely against most bacterial fish pathogens.

  • PDF