• Title/Summary/Keyword: First-onset

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Clinical study on the improvement degree of Bell's palsy with DITI (DITI를 이용한 안면신경마비환자의 호전도에 대한 임상적 고찰)

  • Sung, Byung-Gon;Park, Min-Chul;Lim, Kyu-Sang
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.13 no.2
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    • pp.190-199
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    • 2000
  • We had studied the relationship between the difference of average temperature of Meridian points of left and right face taken by DITI on 1st hospital day and the improvement degree of facial mucles on the patients of Bell's palsy after 10 days treatment. The clinical data and thermographic imaging were analyzed on the 42 cases of Bell's palsy who were treated in the Chunju Oriental Medicine Hospital of Wonkwang University from May to November 1999, and we selected 29 cases within 10 day-onset and the following results were obtained. 1. Assuming the difference of the muscle scores' sums very attending day from after 10 days treatment is improvement degree, and presuming the improvement degree is y, and the mean difference of average temperature between normal and abnormal facial side is x, we can infer the equation of the first degree as following [ y = 2.62 + 2.16 x ]. 2. This means that the higher temperature of nerve falsy side than normal side, the better consequence of treatment we can obtain.

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A clinical study of atopic dermatitis patients as measured by Pulse diagnostic apparatus (맥진기(脈診器)를 이용한 아토피 피부염 환자의 임상적 고찰)

  • Shin, Yoon-Jin;Kim, Yoon-Bum;Yoon, Sang-Heub
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.21 no.2
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    • pp.112-119
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    • 2008
  • Objective : The quantification of pulse diagnosis is an important subject utilizing as a modernization of Oriental medical diagnosis and as a basic data for collaborative access between East and West Medicine. This study was to observe the tendency of pulse diagnosis in atopic dermatitis patients as measured by pulse diagnostic apparatus. Methods : We did pulse diagnostic test about 11 new outpatients who had visited the department of ophthalmology, otolaryngology, dermatology in Kyunghee oriental medical center from March 1, 2007 to October 31, 2007 and had atopic dermatitis. Results : The results were as follows. 1. Among the 11 outpatients, the total number of male patients were 5 and female patients were 6, and the age distribution, the most frequently visited age groups were 10-19 years old and 20-29 years old(each 4 patients). 2. The most common period of onset to first examination were 3 years${\leq}$ (7 patients). 3. There were 8 patients who had emphasized T-wave. 4. There were 7 patients who had repeated pulse wave pattern. Conclusion : In 11 cases who had atopic dermatitis, 8 patients had emphasized T-wave and 7 patients had repeated pulse wave pattern.

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A Study of English Consonants Identified by College Students (대학생들의 영어자음 인지 연구)

  • Yang, Byung-Gon
    • Speech Sciences
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    • v.12 no.3
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    • pp.139-151
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    • 2005
  • Previous studies have shown that Korean students have difficulty identifying some English consonants which are not in the Korean sound inventory. The aim of this study was to examine the accuracy rate of English consonants correctly identified by 130 college students in order to find out which English consonants were difficult for the students to perceive. The subject's task was to identify one of the minimal pairs played in a quiet laboratory classroom. 100 minimal pairs consisted of syllables with various onsets or codas: stops, fricatives, affricates, liquids and nasals. Results were as follows: First, the average score of the English major group was significantly higher than that of the non-English major group. Second, there was a similar distribution in the rank order of minimal pairs sorted by the accuracy rate between the two groups. Third, the accuracy rate systematically decreased as each score range decreased. Fourth, the students showed higher accuracy in the perception of liquids than that of the stop-fricative contrast. Fifth, the accuracy score in onset position was higher than in coda position. Finally, the students still had problem telling voiced consonants from voiceless ones, especially in coda position. It would be desirable to extend the present research to middle or high school students to fundamentally resolve those listening problems.

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How to forecast solar flares, solar proton events, and geomagnetic storms

  • Moon, Yong Jae
    • The Bulletin of The Korean Astronomical Society
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    • v.38 no.2
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    • pp.33-33
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    • 2013
  • We are developing empirical space weather (solar flare, solar proton event, and geomagnetic storm) forecast models based on solar data. In this talk we will review our main results and recent progress. First, we have examined solar flare (R) occurrence probability depending on sunspot McIntosh classification, its area, and its area change. We find that sunspot area and its increase (a proxy of flux emergence) greatly enhance solar flare occurrence rates for several sunspot classes. Second, a solar proton event (S) forecast model depending on flare parameters (flare strength, duration, and longitude) as well as CME parameters (speed and angular width) has been developed. We find that solar proton event probability strongly depends on these parameters and CME speed is well correlated with solar proton flux for disk events. Third, we have developed an empirical storm (G) forecast model to predict probability and strength of a storm using halo CME - Dst storm data. For this we use storm probability maps depending on CME parameters such as speed, location, and earthward direction. We are also looking for geoeffective CME parameters such as cone model parameters and magnetic field orientation. We find that all superstorms (less than -200 nT) occurred in the western hemisphere with southward field orientations. We have a plan to set up a storm forecast method with a three-stage approach, which will make a prediction within four hours after the solar coronagraph data become available. We expect that this study will enable us to forecast the onset and strength of a geomagnetic storm a few days in advance using only CME parameters and the WSA-ENLIL model. Finally, we discuss several ongoing works for space weather applications.

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Co-Infection with Cytomegalovirus and Helicobacter pylori in a Child with $M\acute{e}n\acute{e}$trier's Disease

  • Yoo, Yangho;Lee, Yoon;Lee, Yoo Min;Choe, Yon Ho
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.16 no.2
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    • pp.123-126
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    • 2013
  • $M\acute{e}n\acute{e}$trier's disease is a rare protein-losing gastropathy characterized by hypertrophic gastric fold, foveolar hyperplasia, and hypoproteinemia with resulting peripheral edema. It is clinically evident as nonspecific gastrointestinal symptoms, including abdominal discomfort, nausea and vomiting, abdominal pain, weight loss, diarrhea, and edema. Pediatric $M\acute{e}n\acute{e}$trier's disease usually has an insidious onset and progressive, chronic clinical course and it spontaneously resolves in weeks or months. The pathogenesis of $M\acute{e}n\acute{e}$trier's disease is not clearly understood. $M\acute{e}n\acute{e}$trier's disease is thought to be associated with some gastric infections. But the cause of $M\acute{e}n\acute{e}$trier's disease is unknown, an association with cytomegalovirus (CMV) and Helicobacter pylori has been suggested. In Korea, We present the first a case of pediatric $M\acute{e}n\acute{e}$trier's disease with positive evidence of CMV and H. pylori.

Thermal Analysis of Nickel-Base Superalloys by Differential Scanning Calorimetry (시차주사열량측정법에 의한 니켈기 초내열 합금의 열분석)

  • Yun, Jihyeon;Oh, Junhyeob;Kim, Hongkyu;Yun, Jondo
    • Korean Journal of Materials Research
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    • v.26 no.5
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    • pp.235-240
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    • 2016
  • Appropriate thermo-mechanical properties of nickel-based superalloys are achieved by heat treatment, which induces precipitation and solid solution hardening; thus, information on the temperature ranges of precipitation and dissolution of the precipitates is essential for the determination of the heat treatment condition. In this study, thermal analyses of nickel-based superalloys were performed by differential scanning calorimetry method under conditions of various heating rates of 5, 10, 20, or 40K/min in a temperature range of 298~1573K. Precipitation and dissolution temperatures were determined by measuring peak temperatures, constructing trend lines, and extrapolating those lines to the zero heating rate to find the exact temperature under isothermal condition. Determined temperatures for the precipitation reactions were 813, 952, and 1062K. Determined onset, peak, and offset temperatures of the first dissolution reaction were 1302, 1388, and 1406K, respectively, and those values of the second dissolution reaction were 1405, 1414, and 1462K. Determined solvus temperature was 1462K. The study showed that it was possible to use a simple method to obtain accurate phase transition temperatures under isothermal condition.

Inhibition of Myoblast Differentiation by Polyamine Depletion with Methylglyoxal Bis(guanylhydrazone)

  • Cho, Hwa-Jeong;Kim, Byeong-Gee;Kim, Han-Do;Kang, Ho-Sung;Kim, Chong-Rak
    • BMB Reports
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    • v.28 no.3
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    • pp.191-196
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    • 1995
  • The role of polyamines in skeletal myoblast differentiation was investigated using the polyamine metabolic inhibitor methylglyoxal bis(guanylhydrazone)(MGBG). Concentrations of intracellular free spermidine and spermine increased 2 to 2.5-fold at the onset of myoblast fusion. The systhesis of actin, and creatine kinase activity both dramatically increased during myotube formation. However, MGBG at a concentration of 0.5 mM not only abolished the increase of intracellular free polyamines, but also reduced cell fusion to almost half the level of untreated cells, without noticeable morphological alteration. The production of actin, and creatine kinase activity were almost completely abolished by MGBG. The inhibition of myoblast fusion by MGBG was partially recovered with 0.1 mM of spermidine or spermine added externally. Results indicate that polyamines are necessary for normal myoblast differentiation. Since the first indication of myoblast differentiation is alignment of muscle cells and membrane fusion of adjacent cells, and since polyamine depletion completely inhibited the synthesis of actin, which might be associted with membranes, polyamine might be involved in myoblast differentiation through membrane reorganization events.

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Recent Advances in Intranasal Drug Delivery (경비 약물전달체계의 최근의 진보)

  • Park, Gee-Bae;Lee, Yong-Suk;Lee, Kwang-Pyo
    • Journal of Pharmaceutical Investigation
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    • v.22 no.2
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    • pp.77-96
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    • 1992
  • In recent years intranasal administration of drugs has received great attention as a convenient and efficent method of drug delivery because of its potential to improve the systemic effect of substances with a poor oral bioavailability. In addition to offering advantages such as rapid absorption, fast onset of action and avoiding the first -pass effect, it provides for delivery of drugs from very lipophilic drugs such as steroids to polar and hydrophilic drugs such as peptides and proteins. However, little is still known about the nature of various barriers existing in the nasal mucosae as well as mechanism by which these molecules are absorbed. This review article therefore intends to discuss nasal physiology, experimental methods and evaluation of absorption from the nasal cavity, factors influencing nasal absorption, mechanism of nasal absorption, approaches to improve the residence time and to obtain the sustained-release effect of intranasally administered drugs, promoters and mechanism for the enhancement of nasal absorption, Several examples for intranasal delivery of various systemically effective drugs will be reviewed and illustrated. Drug metabolism in the nasal mucosae and problems associated with intranasal administration of drugs will be also discussed.

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Analysis of Fifty-five Patients with Gasserian Ganglion Block (삼차신경절 차단을 받은 55예의 분석)

  • Lee, Sun-Hak;Kim, Yong-Ik;Kim, Jin-Soo;Cho, Wook-Yeon;Park, Wook
    • The Korean Journal of Pain
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    • v.10 no.1
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    • pp.11-15
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    • 1997
  • Background : There are several treatment of trigeminal neuralgia including Gasserian Ganglion Block. This paper retrospectively analyze the efficacy of Gasserian Ganglion Block as main treatment of trigeminal neuralgia. Methods : We studied 55 patients for followings; sex, age, duration from onset to visit, consulted mediator, causes, characteristics of pain, affected area, types of block, kinds and volume of used neurolytic agents, duration from first block to repeat block, types of repeat block, complications, if surgery was necessary after block. Results : Characteristic items of trigeminal neuralgia are similar with other studies. Mean duration of pain relief was 23 months. The duration was shortened in the repeat block. There were no significant complication. Conclusion : Considering Gasserian Ganglion Block as main treatment of trigeminal neuralgia is an effective and safe method. Therefore we would like to recommend the need to increase public awareness of trigeminal neuralgia and its possible treatment in pain clinics through mass commanication.

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Effects of Air Void at the Steel-Concrete Interface on the Corrosion Initiation of Reinforcing Steel in Concrete under Chloride Exposure

  • Nam Jin-Gak;Hartt William H.;Kim Kijoon
    • Journal of the Korea Concrete Institute
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    • v.17 no.5 s.89
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    • pp.829-834
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    • 2005
  • A series of reinforced G109 type specimens was fabricated and pended with a 15 weight percent NaCl solution. Mix design variables included 1) two cement alkalinities (equivalent alkalinities of 0.32 and 1.08), 2) w/c 0.50 and 3) two rebar surface conditions (as-received and wire-brushed). Potential and macro-cell current between top and bottom bars were monitored to determine corrosion initiation time. Once corrosion was initiated, the specimen was ultimately autopsied to perform visual inspection, and the procedure included determination of the number and size of air voids along the top half of the upper steel surface. This size determination was based upon a diameter measurement assuming the air voids to be half spheres or ellipse. The followings were reached based upon the visual inspection of G109 specimens that were autopsied to date. First, voids at the steel-concrete interface facilitated passive film breakdown and onset of localized corrosion. Based upon this, the initiation mechanism probably involved a concentration cell with contiguous concrete coated and bare steel serving as cathodes and anodes, respectively. Second, the corrosion tended to initiate at relatively large voids. Third, specimens with wire-brushed steel had a lower number of voids at the interface for both cement alkalinities, suggesting that air voids preferentially formed on the rough as-received surface compared to the smooth wire brushed one.