• Title/Summary/Keyword: First-onset

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Clinical Study of Stroke Type (뇌졸중(腦卒中) 환자(患者) 형태(形態)에 관(關)한 임상연구(臨床硏究))

  • Youn, Hyoun-min;Ahn, Chang-beohm;Song, Choon-ho;Son, In-seok;Jang, Kyung-jeon
    • Journal of Acupuncture Research
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    • v.20 no.2
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    • pp.29-41
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    • 2003
  • Clinical observation was made on 52 cases of Stroke that were confined through brain CT, MRI scan. The Stroke cases wee classified into the following kinds cerebral infarction, cerebral hemorrhage, cerebellar or brain stem infarction, cerebellar or brain stem hemorrhage. And among the 52 cases of Stroke cerebral infarction was noticed in 75.00%, cerebral hemorrhage in 11.54%, cerebellar or brain stem infarction in 9.52%, cerebellar or brain stem hemorrhage in 3.85%. The ratio between males and females was 1.74:1 in the whole groups of Stroke and most cases were over 60 of age. As the time of hospitalization, most patients hospitalized from 1 day after stroke to 7 days after stroke. And as the course of hospitalization, most patients hospitalized first. Among the preceding disease at the onset of Stroke hypertention was noted in 32.69%, and deabetes mellitus or heart problem was noted frequently(15.39%). Electrocardiography findings were as follows: The normal was noted in 53.85%, the abnormal in 46.15%. And as the abnormal, left ventricular hypertrophy was noted in 17.54%. The predisposing factors or conditions at the onset of brain infarction were usually initiated during the time of sleeping and those of brain hemorrhage chiefly during the time of exercising like overwork or walking etc. It was noted that smoking a pack of cigarette showed highest disease rate(33.33%) among the average of smoking amount of one day in case of man. Prior to attack, the most chiefly complain was dyspnea or discomfort on chest region. And 30.70% of patients had no previous sign. There were a large number of recurrent cases. The first attack was noted in 71.15%, the 2nd attack in 23.08%, the 3rd attack in 5.77%.

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Epilepsy in children with a history of febrile seizures

  • Lee, Sang Hyun;Byeon, Jung Hye;Kim, Gun Ha;Eun, Baik-Lin;Eun, So-Hee
    • Clinical and Experimental Pediatrics
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    • v.59 no.2
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    • pp.74-79
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    • 2016
  • Purpose: Febrile seizure, the most common type of pediatric convulsive disorder, is a benign seizure syndrome distinct from epilepsy. However, as epilepsy is also common during childhood, we aimed to identify the prognostic factors that can predict epilepsy in children with febrile seizures. Methods: The study comprised 249 children at the Korea University Ansan Hospital who presented with febrile seizures. The relationship between the subsequent occurrence of epilepsy and clinical factors including seizure and fever-related variables were analyzed by multivariate analysis. Results: Twenty-five patients (10.0%) had additional afebrile seizures later and were diagnosed with epilepsy. The subsequent occurrence of epilepsy in patients with a history of febrile seizures was associated with a seizure frequency of more than 10 times during the first 2 years after seizure onset (P<0.001). Factors that were associated with subsequent occurrence of epilepsy were developmental delay (P<0.001), preterm birth (P =0.001), multiple seizures during a febrile seizure attack (P =0.005), and epileptiform discharges on electroencephalography (EEG) (P =0.008). Other factors such as the age at onset of first seizure, seizure duration, and family history of epilepsy were not associated with subsequent occurrence of epilepsy in this study. Conclusion: Febrile seizures are common and mostly benign. However, careful observation is needed, particularly for prediction of subsequent epileptic episodes in patients with frequent febrile seizures with known risk factors, such as developmental delay, history of preterm birth, several attacks during a febrile episode, and epileptiform discharges on EEG.

A Fatal Case of Neonatal Onset Carbamoyl Phosphate Synthetase I Deficiency with Homozygous CPS1 Mutation (동종 접합자 CPS1 돌연 변이를 동반한 신생아 발병형 Carbamoyl Phosphate Synthetase 1 결핍증의 치명적 사례)

  • Yun, Jung Ha;Shin, Seung Han;Ko, Jung Min;Kim, Ee-Kyung;Kim, Han-Suk
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.18 no.1
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    • pp.18-22
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    • 2018
  • Carbamoyl phosphate synthetase I (CPS1) deficiency is a rare autosomal recessive urea cycle disorder that causes hyperammonemic crisis. CPS1 is the first enzyme encoded by the CPS1 gene, which catalyzes the first step of the urea cycle. In CPS1 deficiency, ammonia, the toxic metabolite produced by the interruption of the urea cycle, is accumulated in the blood and brain, leading to hyperammonemic encephalopathy and irreversible brain damage. Here, we report a fatal case of neonatal-onset CPS1 deficiency in a 4-day-old girl presenting with recurrent seizures, who was revealed to be homozygous for c.1529delG ($p.Gly510Alafs^*5$).

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Comparison of Reproductive Parameters of Sow at the Rural Areas of Rangamati District of Bangladesh

  • Chakma, Sumen;Roy, Pantu Kumar;Paul, Ashit Kumar;Alam, M. Golam Shahi;Juyena, Nasrin Sultana
    • Journal of Embryo Transfer
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    • v.29 no.3
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    • pp.305-311
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    • 2014
  • It is imperative to know the reproductive parameters of the existing swine breed for profitable farming in Bangladesh. This study was designed to determine the reproductive parameters of sows at hilly areas. A total of 245 pigs with 47 breedable sows were included. The data on age at puberty, oestrous cycle length, oestrus duration, gestation length, interval between furrowing and onset of oestrus, first service pregnancy rate, service per pregnancy and number of piglets born per sow in local and cross bred sows were determined. The present study revealed that age at puberty of local and cross breed sows was $232.5{\pm}8.4$, $221.3{\pm}6.9$ days, respectively. Oestrous duration was $41.1{\pm}3.1$ hours. The interval between furrowing and onset of oestrus was shorter in cross bred sows. There was no variation in values of oestrus cycle length and gestation length. The first service pregnancy rate was higher in both the local and cross bred sow. Number of piglets per sow per farrowing was $6.1{\pm}2.2$ and 60.9% local sows gave birth of 3 to 5 piglets per farrowing whereas 75.0% cross bred sows gave birth of 6 to 9 piglets. These results suggest that reproductive parameters of local sow need to be improved for better production, and cross bred sows should be reared for obtaining expected productivity.

Case Report: Improvement of 3 Stroke Patients Through Integrative Medicine Based on Scalp Acupuncture (두침치료를 위주로 한 의한협진을 통해 호전된 뇌졸중 환자 3례의 증례보고)

  • Siyoung Song;Esther Jang;Joonyong Noh;Soomin Jo;Eunseo Kim;Geunjeong Kim;Kyungok Kim;Jaeuk Sul;Changsu Na
    • Korean Journal of Acupuncture
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    • v.41 no.3
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    • pp.118-126
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    • 2024
  • A stroke is a condition where an ischemic injury occurs in the brain tissue due to blockage or rupture of cerebral blood vessels. The damage to the brain nerve cells caused by a stroke is irreversible. Significant recovery is generally observed within the first six months after the onset, but the natural recovery rate decreases after six months. Therefore, intensive rehabilitation therapy is necessary within the first six months of the onset. This case report presents three cases of patients in the sequelae phase of stroke, where treatments based on integrative medicine system between traditional Korean medicine and Western medicine were applied. The treatments included scalp acupuncture from traditional Korean medicine and rehabilitation exercises and electrical therapy from Western medicine. In this case report, we evaluated the Manual Muscle Test (MMT), Modified Barthel Index (MBI), and the patients' subjective symptom interviews before and after the implementation of the integrative treatment. As a result, significant improvements in MMT and MBI were observed in acute stroke cases, whereas the improvement was minimal in cases with chronic progression. However, in all cases, the patients expressed high satisfaction with the treatment during the interviews.

Epilepsy syndromes during the first year of life and the usefulness of an epilepsy gene panel

  • Lee, Eun Hye
    • Clinical and Experimental Pediatrics
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    • v.61 no.4
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    • pp.101-107
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    • 2018
  • Recent advances in genetics have determined that a number of epilepsy syndromes that occur in the first year of life are associated with genetic etiologies. These syndromes range from benign familial epilepsy syndromes to early-onset epileptic encephalopathies that lead to poor prognoses and severe psychomotor retardation. An early genetic diagnosis can save time and overall cost by reducing the amount of time and resources expended to reach a diagnosis. Furthermore, a genetic diagnosis can provide accurate prognostic information and, in certain cases, enable targeted therapy. Here, several early infantile epilepsy syndromes with strong genetic associations are briefly reviewed, and their genotype-phenotype correlations are summarized. Because the clinical presentations of these disorders frequently overlap and have heterogeneous genetic causes, next-generation sequencing (NGS)-based gene panel testing represents a more powerful diagnostic tool than single gene testing. As genetic information accumulates, genetic testing will likely play an increasingly important role in diagnosing pediatric epilepsy. However, the efforts of clinicians to classify phenotypes in nondiagnosed patients and improve their ability to interpret genetic variants remain important in the NGS era.

Effect on Conception for Insemination Method of Frozen Semen in Cheju Native Cattle. II. Effect of time and site of insemination (제주한우에 있어서 동결정액 수정방법이 수태에 미치는 영향 제II보 동결정액의 수정시기와 주입부위가 수태에 미치는 영향)

  • 김중규;장덕지
    • Korean Journal of Animal Reproduction
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    • v.8 no.2
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    • pp.87-91
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    • 1984
  • This study was conducted to determine the optimum time and the insemination site of frozen in Cheju native cows, and 660 cows first service inseminated with rectovaginal methods by 3 skillful technicians as 3 districts near Cheju City and Sogwipo City areas obtained the following results. Optimum time for insemination was 16-20 hours after the onset of estrus and 80.6% of 67 conceived to first insemination. In the rectovaginal technique used widely at present conception rate for the palpation of ovaries showed 6.6% (index) higher than that of non-palpation. Conception rate of the insemination site; the intra-uterine horn, intra-uterus, just inside the cervix and depositing in mid-cervix were 62.5, 78.4, 74.6, and 80.9% respectively, however, there was no difference in conception rate between cervical and uterine deposition of forzon semen except for the intra-uterine horn.

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The H1*-H2* Measure

  • Ahn, Hyun-Kee
    • Speech Sciences
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    • v.7 no.2
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    • pp.85-95
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    • 2000
  • In this paper, the H1*-H2* measure is introduced and exact procedures for obtaining the H1*-H2* value are fully specified, The H1*-H2* measure (a corrected difference in dB between the first and second harmonics) has been devised to provide an acoustic correlate of the phonation mode of a vowel following a consonant. With this measure, we can investigate the phonation mode of a vowel that is free from the F1 amplitude perturbation effect caused by the preceding consonant, which is especially salient at the voicing onset position of the vowel. For identical research purposes, on the other hand, the H1-H2 measure (the observed difference in dB between the first and second harmonic) has been employed in many previous studies. This paper compares these two measures by illustrating experimental results of exploring post-release phonation modes of vowels following the different manner classes of stop consonants in Korean $\square$i.e., the tense, lenis, and aspirated stops.

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ENHANCEMENT OF NORMAL AND NEOPLASTIC MAMMARY GROWTH BY CROSSBREEDING BETWEEN STRAINS OF FEMALE AND MALE MICE WITH HIGH MAMMARY GROWTH POTENTIALS

  • Nagasawa, Hiroshi;Koshimizu, U.;Yamamoto, K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.1 no.1
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    • pp.43-46
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    • 1988
  • Based on our previous results that among 4 strains of mice SHN and GR/A showed the highest mammary growth potentials in females and males, respectively. Effects of crossbreeding on normal and neoplastic mammary growth were studied in $(SHN\;{\times}\;GR/A)F_1$ virgin female mice. $F_1$ mice were higher than the parental strains in the end-bud formation and the ductal growth of mammary glands at 60 days of age and at tumorous age, respectively. While there was little difference between $F_1$ and both parental strains in the onset age of the first mammary tumors, mammary tumorigenic potential was apparently higher in the former than in the latters. This would be the first report that demonstrated directly the contribution of mammary growth potential of males to that of female offspring.

Binary Nature Revealed in Circumstellar Spiral-Shell Patterns

  • Kim, Hyosun;Hsieh, I-Ta;Liu, Sheng-Yuan;Taam, Ronald E.
    • The Bulletin of The Korean Astronomical Society
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    • v.39 no.1
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    • pp.56.1-56.1
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    • 2014
  • With the advent of high-resolution high-sensitivity observations, spiral patterns have been revealed around several asymptotic giant branch (AGB) stars. Such patterns can provide possible evidence for the existence of central binary stars embedded in outflowing circumstellar envelopes. It is, however, not generally recognized that the binary induced pattern, vertically extended from the orbital plane, exhibits a ring-like pattern with an inclined viewing angle. I will first review the binary-induced spiral-shell patterns on the AGB circumstellar envelopes with the effect of inclination angle with respect to the orbital plane, of which large inclination cases reveal incomplete ring-like patterns. I will describe a method of extracting such spiral-shell from the gas kinematics of an incomplete ring-like pattern to place constraints on the characteristics of the (unknown) central binary stars. This first success may open the possibility of connecting the ring-like patterns commonly found in the AGB circumstellar envelopes and in the outer parts of (pre-)planetary nebulae and pointing to the conceivable presence of central binary systems, which may give a clue for the onset of asymmetrical planetary nebulae.

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