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A Clinical Trial of Dextranase-Containing Mouthwash on the Inhibition of Plaque Formation and Gingivitis (Dextranase 함유 구강 세정액의 치태 억제 및 치은염 예방 효과에 관한 임상적 연구)

  • Song, Woo-Sung;Son, Eun-Ju;Kim, Do-Man;Chung, Hyun-Ju
    • Journal of Periodontal and Implant Science
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    • v.31 no.2
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    • pp.371-388
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    • 2001
  • A novel glucanhydrolase(DXAMase) from a mutant of Lipomyces starkeyi(KSM 22) has been shown effective in hydrolysis of mutan, reduction of mutan formation by Streptococcus mutans and removal pre-formed sucrose-dependentadherent microbial film and DXAMase has been strongly bound to hydroxyapatitie. These in vitro properties of Lipomyces starkeyi DXAMase are desirable for its application as a dental plaque control agent. This study was performed to determine the adjunctive oral hygiene benefits and safety of dextranase(Lipomyces starkeyi KSM 22 DXAMase)-containing mouthwash when used alongside normal tooth-brushing. This 6-month clinical trial was placebo-controlled double-blind design evaluating 1U/ml dextranase mouthwash and 0.12% chlorhexidine mouthwash. A total 39 systemically healthy subjects, who had moderate levels of plaque and gingivitis were included. At baseline, 1, 3 and 6 months, subjects were scored for plaque accumulation(Turesky modification of Quingley-Hein's plaque index), gingivitis status($L\ddot{o}e$ and Silness gingival index), and tooth stain(Area and severity index system by Lang et al). Additionally, oral mucosal examinations were performed and subjects questioned for adverse symptoms. Two weeks after pre-experiment examinations and a professional prophylaxis, the subjects provided with allocated mousewash and instructed to use 20-ml volumes for 30s twice daily after toothbrushing. All the groups showed significant increase in plaque accumulation since 1 month of experiment. During 6 months' period, the Dextranase mouthwash group showed the least increase in plaque accumulation, compared to the Chlorhexidine mouthwash and placebo groups. As for gingival inflammation, all the groups showed significant increase during 6 months of experiment. The Experimental group(Dextranase mouthwash) also showed the least increase in gingival index score, compared to the Positive control(Chlorhexidine mouthwash)as well as the Negative control(placebo)groups. Whereas the tooth stain was increased significantly in the Positive control group, compared to the baseline score and the Negative controlgroup since 3 months of mouthrinsing. It was significantly increased after 6 months in the Experimental group, still less severe than the Positive control group. As for the oral side effect, the Experimental group showed less tongue accumulation, bad taste, compared to the Positive control group. From these results, mouthrinsing with Lipomyces starkeyi KSM 22 dextranase provided adjunctive benefits to toothbrushing, comparable to 0.12% chlorhexidine mouthwash in inhibition of plaque accumulation and gingival inflammation and local side effects were if anything less frequent and less intense than chlorhexidine, with long-term use of the mouthwash. All data had provided positive evidence for Lipomyces starkeyi KSM 22 dextranase as an antiplaque agent and suggested that further development of dextranase formulations for plaque control are warranted.

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Effect of Packaging Materials on the Quality of Radish Sprout during Storage (포장재가 무순의 저장 중 품질특성에 미치는 영향)

  • Lee, Hyeon-Jeong;Jang, Ji-Hyun;Kwon, Joong-Ho;Moon, Kwang-Deog
    • Food Science and Preservation
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    • v.16 no.2
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    • pp.147-154
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    • 2009
  • Radish sprout was packaged with different materials. PO and PC are both hard case PET(polyethylenterephthalate) and has 6 holes and no holes, respectively. LO, LM and LH are anti-fogging OPP(oriented polypropylene) film which have different oxygen transmission rates. The oxygen concentration and weight loss rate in PO packaged were higher than any other packages. The soluble solid contents of radish sprouts packaged with PO showed much increased during storage. The pH increased during storage but pH of the samples packaged with high oxygen transmission rate was relatively low. Radish sprouts in LO had lower b value as compared to other samples. The result of ${\Delta}E$ value was generally high during storage period, especially at 7 days storage. The contents of total polyphenolic compounds and free radical scavenging activity of radish sprout packaged with PC and LO were high. Total aerobic bacteria of sprouts in PC and LO was much higher than others. The result of organoleptic qualities showed that the radish sprouts packaged with LM had a good score in terms of overall acceptability until 7 days storage.

Quality and Shelf-Life of Vacuum Packed RTE (Ready-To-Eat) Hamburg Steak Depending on the Oxygen Permeability of Packaging Material and the Storage Temperature (포장재의 산소투과도와 저장온도에 따른 즉석섭취형 햄버그스테이크의 품질 및 저장성)

  • Lim, Ji Hoon;Lee, Sung Ki;Chung, Seung Hee;Lee, Keun Taik
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.22 no.3
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    • pp.95-102
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    • 2016
  • This study investigated the effects of the oxygen permeability of vacuum packaging film and the storage temperature on the quality and shelf life of Hamburg steaks during storage for 14 days. Control samples (C) were packaged in a polyamide/polyethylene (PA/PE) film and stored at $5^{\circ}C$. Treatment samples were either packaged in an ethylene vinyl alcohol/polyethylene (EVOH/PE) copolymer film and stored at $5^{\circ}C$ (T1), and in a PA/PE film and stored at $-18^{\circ}C$ (T2). The initial total plate count (TPC) was 3.6 log cfu/g. In T1 samples, TPC and Brochothrix thermosphacta counts were increased, similar to those in C samples, whereas Pseudomonas spp. counts were significantly lower than those in C samples during storage. Over the storage period, the volatile basic nitrogen values increased most rapidly in C samples, followed by T1 and then T2 samples. The values of thiobarbituric acid reactive substances steadily increased in all samples during storage. The colour parameters were not significantly different among the samples during storage. T1 samples maintained sensory qualities in flavour and off-odour parameters for two days longer than C samples did. At day 12, T2 samples were evaluated as being below the marketability score of 5.0 for texture. In conclusion, using high oxygen barrier films like EVOH/PE copolymer for packaging Hamburg steaks could extend the sensory qualities in view of flavour and off-odour during chilled storage. However, frozen storage at $-18^{\circ}C$ is recommended when the storage period is extended beyond 14 days at $5^{\circ}C$.

Effect of Sizes of Boiled-Dired Anchovies on the Storage Stability (건멸치의 크기가 저장성에 미치는 영향)

  • Jo, Kil-Suk;Kim, Hyun-Ku;Kim, Young-Myoung;Kang, Tong-Sam
    • Korean Journal of Food Science and Technology
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    • v.20 no.1
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    • pp.1-5
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    • 1988
  • Changes in the quality characteristics of three sizes of boiled-dried anchovies packaged in kraft paper laminated with 0.03 mm PE film during storage for six months at $5^{\circ}C$ were studied. In case of Dae-myul (78-80mm), the reaction of thiobarbituric acid, browning rate of lipid oxidation and Hunter-Scale color values. L, a, and b, were higher than those in Joong-myul (45-49 mm) or So-myul (30-34 mm). Organoleptic evaluation suggests that boiled-dried anchovy be good in sequence as So-myul, Joong-myul and Dae-myul. Shelf life of Dae-myul was half times lower than that of Joong-myul or So-myul. Regression equation for the sensory score prediction with lipid oxidative browning was determined.

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Movie Box-office Analysis using Social Big Data (소셜 빅데이터를 이용한 영화 흥행 요인 분석)

  • Lee, O-Joun;Park, Seung-Bo;Chung, Daul;You, Eun-Soon
    • The Journal of the Korea Contents Association
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    • v.14 no.10
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    • pp.527-538
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    • 2014
  • The demand prediction is a critical issue for the film industry. As the social media, such as Twitter and Facebook, gains momentum of late, considerable efforts are being dedicated to prediction and analysis of hit movies based on unstructured text data. For prediction of trends found in commercially successful films, the correlations between the amount of data and hit movies may be analyzed by estimating the data variation by period while opinion mining that assigns sentiment polarity score to data may be employed. However, it is not possible to understand why the audience chooses a certain movie or which attribute of a movie is preferred by using such a quantitative approach. This has limited the efforts to identify factors driving a movie's commercial success. In this regard, this study aims to investigate a movie's attributes that reflect the interests of the audience. This would be done by extracting topic keywords that represent the contents of Twits through frequency measurement based on the collected Twitter data while analyzing responses displayed by the audience. The objective is to propose factors driving a movie's commercial success.

Clinical and Radiologic Results of Arthroscopic Treatment for Osteochondral Lesion with Subchondral Cyst on Talus (연골하 낭종을 동반한 거골의 골연골 병변의 관절경적 치료 후 임상적 결과 및 방사선학적 변화)

  • Lee, Jin-Woo;Park, Kwan-Kyu;Kim, Sung-Jae;Hahn, Soo-Bong;Kang, Eung-Shick
    • Journal of Korean Foot and Ankle Society
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    • v.7 no.1
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    • pp.21-29
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    • 2003
  • Purpose: The purpose of this study is to review clinical and radiologic changes after arthroscopic operation without bone graft for osteochondral lesion with subchondral cyst on the talus. And we compared the results with those without cyst. Radiologic changes were also observed. Materials and Methods: Arthroscopic microfrature or abrasion arthroplasty was performed on 10 caeses of osteochondral lesions with subchondral cyst and 20 cases without cysts. Preoperative and postoperative symptoms were evaluated by Ankle-Hind foot scale of AOFAS and the score of two groups were compared(t-Test : Paired Two Test for Means). Radiologic evaluation was performed after operation on patients with osteochondral lesion with cyst. Results: On patients of osteochondral lesion with subchondral cyst on talus, there was clinical improvement compared to the preoperative status and compared to patients without cysts(P=0.01) after arthroscopic operation. We could get increase of density and decrease of size of cystic lesion on plain film with time passage. Conclusion: We report 10 cases with osteochondral lesion with subchondral cyst on talus which resulted in clinical and radiological improvement after arthroscopic microfracture or abrasion arthroplasty without bone graft.

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A Comparative Evaluation about Force and Fatigue on Thumb according to Input Type for Repetitive Use of Mobile Phone (모바일 폰의 반복 사용 시 압력방식에 따라 엄지손가락에 발생하는 힘과 피로에 대한 비교평가)

  • Kim, K.M;Park, J.H.;Kim, G.H.;Son, K.
    • Journal of Biomedical Engineering Research
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    • v.32 no.4
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    • pp.312-318
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    • 2011
  • The purpose of study was to evaluate effects for repetitive use of thumb according to two different input types (button and touch) of mobile phones. A total of eight young and healthy subjects (6 males and 2 females: $24.63{\pm}8.04$ years) volunteered, and force measurement on thumb using film type pressure sensor was carried out for an hour. Before the experiment De Quervain's syndrome test were performed to check the left and right muscles related with thumb motion and after measuring the pressing force fatigue feeling survey achieved. For a statistical analysis, 1-to-5 ranking scale was used to score the fatigue feeling. From the result of pressure measurement, forces acting on thumb in button type were 3.36 times (the right thumb) and 3.16 times (the left thumb) for the touch type. And the result of survey, fatigue by using the button type of mobile phone was largely triggered than by using touch type. The abductor pollicis brevis and the flexor pollicis brevis were found as common part of fatigue for repetitively using thumb during texting messages. In the further study, some quantitative fatigue comparisons for various input motions are required to analyze repetitive strain injury syndrome.

Variable Heart Rate Variability Measurements Induced by Wearing Color Glasses and Their Relationship with Hanyeol or Joseup Patterns of Korean Medicine Diagnostics, a Preliminary Observation (색채자극에 따른 심박변이도 변화와 한열조습변증의 상관성)

  • Yin, Chang-Shik;Kim, Sun-Hyun;Lee, Neung-Gi;Lee, Woo-Cheol;Koh, Hyeong-Gyun;Park, Young-Bae;Chun, Sae-Il
    • The Journal of the Society of Korean Medicine Diagnostics
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    • v.10 no.2
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    • pp.79-87
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    • 2006
  • Objective : Biologic responses to color stimulation was observed and analyzed in relation with Korean medicine diagnostics. Methods : Twelve volunteers participated and completed the questionnaire on Hanyeol or Joseup patterns of Korean medicine diagnostics. Standard deviation of RR intervals (SDNN), an overall indicator of heart rate variability, was measured while wearing partially transparent acetate film glasses of various colors: (1) transparency or black, (2) red, green, or blue, or (3) cyan, or yellow. Results : Different responses to the color environmental stimulation were observed. Yeol pattern score was inversely related with the SDNN value under red color stimulation. Conclusion : This line of observations may serve as a basis of clinical application of color therapy, in particular, in relation with pattern diagnosis of Korean medicine, and may be applied in combination with existing electrodermal meridian measurement systems for better evaluation of Gi (life energy) phenomenon.

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Soil Quality Assessment Method of Paddy and Upland (논과 밭토양의 질 평가 방법)

  • Yoon, Jung-Hui;Jung, Beung-Gan;Jun, Hee-Joong;Kwak, Han-Kang
    • Korean Journal of Soil Science and Fertilizer
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    • v.37 no.6
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    • pp.357-364
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    • 2004
  • Modern agriculture depending on chemicals such as fertilizers and pesticides gave rise to questions about long-term sustainability of agriculture in relation to degradation of soil quality. Improving soil quality is prerequisite to sustain biological productivity, maintain environmental quality, and promote plant and animal health. Assessment and monitoring of the health and quality of soil is necessary to provide opportunity to evaluate and redesign soil management system for sustainability. To develop the soil quality assessment method, we collected national data on soil properties of paddy and upland and attempted to evaluate the data in aspect of soil quality by the process of selecting a minimum data set (MDS), scoring the soil properties and calculating soil quality index (SQI) integrating the score of each soil property. This approximation indicated that soil quality index was in the order of paddy soil, upland soil and plastic film house soil.

A Study on the Effectiveness of Media Based Cultural Studies - Center of creativity education of university students (미디어 기반 교양교과 효과 검증 연구 - 대학생의 창의성 교육 중심으로)

  • Kim, Seong-Won;Youn, Jeong-Jin
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.7 no.7
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    • pp.193-201
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    • 2017
  • The purpose of this study is to examine the effect of creativity education on creativity of college students through educational medium such as film, animation, documentary, cartoon, advertisement, etc. Therefore, D university in Busan Metropolitan City held a 15-week creativity program for team college students in the second semester of 2016 "creative convergence". In this study, the data collected by the pre - test and post - test using the creativity questionnaire were analyzed by SPSS 18.0 program. The results of this study are as follows. First, the creativity of college students showed a significant difference in problem solving ability scores in the curriculum for media literacy. Second, the creativity of university students showed a significant difference in creative tendency score in media literacy curriculum. The fact that various media such as movies, animations, documentaries, cartoons, advertisements, etc. are educational media that can be easily accessed in everyday life, suggests that the improvement of creativity suggests educational effects to college students and future students.